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The map label for this gene is lytB [H]

Identifier: 86605905

GI number: 86605905

Start: 1233034

End: 1234773

Strand: Reverse

Name: lytB [H]

Synonym: CYA_1221

Alternate gene names: 86605905

Gene position: 1234773-1233034 (Counterclockwise)

Preceding gene: 86605906

Following gene: 86605904

Centisome position: 42.1

GC content: 63.16

Gene sequence:

>1740_bases
ATGGCCAGTTGTCAGTCTCCTACTGCCCAACCTCGCCGGTTTTTAAGGACTCCGCTCCGCTGGCGCAAACAGAGCAGCCT
CATTTCCGGCTTGGGCCTGTTGCTGACAGCCTTGGTGCTCCGTGCCGCTGACGCGACCGGGGTTCGCAAAGAGGCCGAAG
ATCCTGTCTTGCCAGCGCAATTGTCTGCAGCGGCCACCCCCGAAAACCCGATCCTGCACGTGGGCATTGTGCAACGCTTT
GGCCGTTCTGAGCAAGATCAGGTGGAGCTGGCAGCGCCGCTGGGGTCTTTCCTCACCCTGGAATTTGCCCAGGCAGACGG
CAGCACCCAGAGGCAGCGGCTCCCACAAGTTACGGTTGGGATCGTCAACCGCGCCCTGGCCAGCCCGGAAACCGTGTACC
GCCTCATCCTCAGCAGCCACAAAAGCTTCGAGAGCGCCGAGGCCAGCGCCAACTCCTGGGAATCTCTGGGCATCCGCACC
GAGATCGCCCAACCGCAGGAATGGCAGGTGTGGGCCAGCCGCGCCTACACTCCCCAACAACTAATCCAGATTCAGCAGTA
TGCCCAGAAAGAAGGGATCCCTCAGGTGCGGCTGGAGGTGCAGGAGCGGCGCGAACGGGCGGAGCTGAGCTGGGTACATG
AGCATTTTCGCTACCATCGCACCCGCCTGAGGGTAACCTCCGATGCCGGCTATCTGCGGGTGAACGACCGCTACTATGCC
GGATCCATTACCATTCAGCCCAATGCCTACGGCAGCTATACGGTGGTCAACGCCGTGCCCCTGGAAACCTATTTACGGGG
GGTGGTGCCCCATGAGGTGGGGCCAGGGGCCCCCTTTGCCGCCATGGCCGCCCAGGCAATTTTGGCGCGCACCTACGCCC
TCAAGAACCTGCACCGCTTTCAGATCGACGACTACCACCTCTGTGCCAATACCCACTGCCAGGTTTACAAGGGGCTGAGC
GGCACCCATCCGCGGGCCGACGAAGCGATTCGCCAGACCAGCGGCCTGGTGCTCACCTACAAGGGCGAGCTGGTGGATGC
CGTTTATTCTTCCACCAACGGCGGCATCTCGGCAGGCTTTGAAGAGGTTTGGGACGGAGAGCCGCGCCCCTACCTGCGCC
CGCAGGTGGATATCGCCCACCAGCCCGATCAGCCCTTCGATTTGCGGCAGGAGAGCGACTTCAAGGCCTTTCTGGCCCGG
CGGGAGGGTTTCAACGAAGCAGGGGTATCGCGCCTCTTCCGCTGGGAGTTTTCTCAGTCGCTGGAGGAGCTAAACGCCCA
ACTGCGGGCCGCTCAAGAGTACCTCGGGATCCCTCTCCCCGAGTGGATGACCATCCAGGGGCTGCACGTCCTGGAGCGCT
CGGTCAGTGGTCGGGTGCAGGCGCTGCACGTGGACTTGCAGACGCCCCAAGGGCTCCACTCGATTCTTTTGCGCAAGGAT
CAGGTGCGCCTGGCTTTTCCCCGCCTGTACAGCACTCTGTTTCGCGTGGAACCCCTGAAACAGAGCGGGCGGCTGACAGG
CTACCGCTTTATCGGCGGCGGCTTTGGCCACGGGGTGGGGCTGAGCCAGTACGGCGCCTACACCCTGGCGCGGCGGGGGT
TGAACGCGGCGCAAATCCTCGCCTTTTACTACCCCGGCACCACCCTGGCCGAGCTGGGATCCCTCTCCCTGCAGTTGCCT
GAGGTTTCCCTGGCCTTTGACAGTAGCCAGGCGCAGTCCTGGTCCGGCTACCAGAGATAG

Upstream 100 bases:

>100_bases
AAAGCAGGGAGGTAGAGGGGAGAGGAGCATCCATCGCTGCGGCTAGGCCAGAAAAGATGCGGGTACAATCGACAGGGTGT
GTTGTCAGGATAAAGCGGCC

Downstream 100 bases:

>100_bases
GGGGCACGATGGAAGAAGAGCGACGGGAACGCGGCCATCCCCCTCTTCGGGATCCCGCTCCAGAGGAAGGGTGGCAGGAA
GGGGCGGCCCAAGCGCCGCC

Product: SpoIID/LytB domain-containing protein

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP76; CWBP76; Modifier protein of major autolysin [H]

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MASCQSPTAQPRRFLRTPLRWRKQSSLISGLGLLLTALVLRAADATGVRKEAEDPVLPAQLSAAATPENPILHVGIVQRF
GRSEQDQVELAAPLGSFLTLEFAQADGSTQRQRLPQVTVGIVNRALASPETVYRLILSSHKSFESAEASANSWESLGIRT
EIAQPQEWQVWASRAYTPQQLIQIQQYAQKEGIPQVRLEVQERRERAELSWVHEHFRYHRTRLRVTSDAGYLRVNDRYYA
GSITIQPNAYGSYTVVNAVPLETYLRGVVPHEVGPGAPFAAMAAQAILARTYALKNLHRFQIDDYHLCANTHCQVYKGLS
GTHPRADEAIRQTSGLVLTYKGELVDAVYSSTNGGISAGFEEVWDGEPRPYLRPQVDIAHQPDQPFDLRQESDFKAFLAR
REGFNEAGVSRLFRWEFSQSLEELNAQLRAAQEYLGIPLPEWMTIQGLHVLERSVSGRVQALHVDLQTPQGLHSILLRKD
QVRLAFPRLYSTLFRVEPLKQSGRLTGYRFIGGGFGHGVGLSQYGAYTLARRGLNAAQILAFYYPGTTLAELGSLSLQLP
EVSLAFDSSQAQSWSGYQR

Sequences:

>Translated_579_residues
MASCQSPTAQPRRFLRTPLRWRKQSSLISGLGLLLTALVLRAADATGVRKEAEDPVLPAQLSAAATPENPILHVGIVQRF
GRSEQDQVELAAPLGSFLTLEFAQADGSTQRQRLPQVTVGIVNRALASPETVYRLILSSHKSFESAEASANSWESLGIRT
EIAQPQEWQVWASRAYTPQQLIQIQQYAQKEGIPQVRLEVQERRERAELSWVHEHFRYHRTRLRVTSDAGYLRVNDRYYA
GSITIQPNAYGSYTVVNAVPLETYLRGVVPHEVGPGAPFAAMAAQAILARTYALKNLHRFQIDDYHLCANTHCQVYKGLS
GTHPRADEAIRQTSGLVLTYKGELVDAVYSSTNGGISAGFEEVWDGEPRPYLRPQVDIAHQPDQPFDLRQESDFKAFLAR
REGFNEAGVSRLFRWEFSQSLEELNAQLRAAQEYLGIPLPEWMTIQGLHVLERSVSGRVQALHVDLQTPQGLHSILLRKD
QVRLAFPRLYSTLFRVEPLKQSGRLTGYRFIGGGFGHGVGLSQYGAYTLARRGLNAAQILAFYYPGTTLAELGSLSLQLP
EVSLAFDSSQAQSWSGYQR
>Mature_578_residues
ASCQSPTAQPRRFLRTPLRWRKQSSLISGLGLLLTALVLRAADATGVRKEAEDPVLPAQLSAAATPENPILHVGIVQRFG
RSEQDQVELAAPLGSFLTLEFAQADGSTQRQRLPQVTVGIVNRALASPETVYRLILSSHKSFESAEASANSWESLGIRTE
IAQPQEWQVWASRAYTPQQLIQIQQYAQKEGIPQVRLEVQERRERAELSWVHEHFRYHRTRLRVTSDAGYLRVNDRYYAG
SITIQPNAYGSYTVVNAVPLETYLRGVVPHEVGPGAPFAAMAAQAILARTYALKNLHRFQIDDYHLCANTHCQVYKGLSG
THPRADEAIRQTSGLVLTYKGELVDAVYSSTNGGISAGFEEVWDGEPRPYLRPQVDIAHQPDQPFDLRQESDFKAFLARR
EGFNEAGVSRLFRWEFSQSLEELNAQLRAAQEYLGIPLPEWMTIQGLHVLERSVSGRVQALHVDLQTPQGLHSILLRKDQ
VRLAFPRLYSTLFRVEPLKQSGRLTGYRFIGGGFGHGVGLSQYGAYTLARRGLNAAQILAFYYPGTTLAELGSLSLQLPE
VSLAFDSSQAQSWSGYQR

Specific function: Possibly involved in cell wall metabolism during spore formation. Enhances the amidase activity approximately threefold [H]

COG id: COG2385

COG function: function code D; Sporulation protein and related proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein. Secreted, cell wall. Note=Cell wall localization shown in PubMed:11987133 [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR013486
- InterPro:   IPR013693 [H]

Pfam domain/function: PF04122 CW_binding_2; PF08486 SpoIID [H]

EC number: NA

Molecular weight: Translated: 64669; Mature: 64538

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASCQSPTAQPRRFLRTPLRWRKQSSLISGLGLLLTALVLRAADATGVRKEAEDPVLPAQ
CCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
LSAAATPENPILHVGIVQRFGRSEQDQVELAAPLGSFLTLEFAQADGSTQRQRLPQVTVG
HHCCCCCCCCEEEEHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHCCHHHHH
IVNRALASPETVYRLILSSHKSFESAEASANSWESLGIRTEIAQPQEWQVWASRAYTPQQ
HHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCHHHCCCEEECCCCCHHHHHHHCCCCHHH
LIQIQQYAQKEGIPQVRLEVQERRERAELSWVHEHFRYHRTRLRVTSDAGYLRVNDRYYA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCEEEE
GSITIQPNAYGSYTVVNAVPLETYLRGVVPHEVGPGAPFAAMAAQAILARTYALKNLHRF
EEEEECCCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
QIDDYHLCANTHCQVYKGLSGTHPRADEAIRQTSGLVLTYKGELVDAVYSSTNGGISAGF
CCCCEEEECCCCHHHCCCCCCCCCCHHHHHHHHCCEEEEECCHHHHHHHHCCCCCCCCCH
EEVWDGEPRPYLRPQVDIAHQPDQPFDLRQESDFKAFLARREGFNEAGVSRLFRWEFSQS
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LEELNAQLRAAQEYLGIPLPEWMTIQGLHVLERSVSGRVQALHVDLQTPQGLHSILLRKD
HHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCC
QVRLAFPRLYSTLFRVEPLKQSGRLTGYRFIGGGFGHGVGLSQYGAYTLARRGLNAAQIL
CHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHEE
AFYYPGTTLAELGSLSLQLPEVSLAFDSSQAQSWSGYQR
EEECCCCHHHHHCCCEEECCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
ASCQSPTAQPRRFLRTPLRWRKQSSLISGLGLLLTALVLRAADATGVRKEAEDPVLPAQ
CCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
LSAAATPENPILHVGIVQRFGRSEQDQVELAAPLGSFLTLEFAQADGSTQRQRLPQVTVG
HHCCCCCCCCEEEEHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHCCHHHHH
IVNRALASPETVYRLILSSHKSFESAEASANSWESLGIRTEIAQPQEWQVWASRAYTPQQ
HHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCHHHCCCEEECCCCCHHHHHHHCCCCHHH
LIQIQQYAQKEGIPQVRLEVQERRERAELSWVHEHFRYHRTRLRVTSDAGYLRVNDRYYA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCEEEE
GSITIQPNAYGSYTVVNAVPLETYLRGVVPHEVGPGAPFAAMAAQAILARTYALKNLHRF
EEEEECCCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
QIDDYHLCANTHCQVYKGLSGTHPRADEAIRQTSGLVLTYKGELVDAVYSSTNGGISAGF
CCCCEEEECCCCHHHCCCCCCCCCCHHHHHHHHCCEEEEECCHHHHHHHHCCCCCCCCCH
EEVWDGEPRPYLRPQVDIAHQPDQPFDLRQESDFKAFLARREGFNEAGVSRLFRWEFSQS
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LEELNAQLRAAQEYLGIPLPEWMTIQGLHVLERSVSGRVQALHVDLQTPQGLHSILLRKD
HHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCC
QVRLAFPRLYSTLFRVEPLKQSGRLTGYRFIGGGFGHGVGLSQYGAYTLARRGLNAAQIL
CHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHEE
AFYYPGTTLAELGSLSLQLPEVSLAFDSSQAQSWSGYQR
EEECCCCHHHHHCCCEEECCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1357079; 1356138; 9384377 [H]