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The map label for this gene is tas

Identifier: 86605676

GI number: 86605676

Start: 989224

End: 990264

Strand: Reverse

Name: tas

Synonym: CYA_0976

Alternate gene names: 86605676

Gene position: 990264-989224 (Counterclockwise)

Preceding gene: 86605677

Following gene: 86605675

Centisome position: 33.77

GC content: 63.3

Gene sequence:

>1041_bases
ATGCGCTACCGCCAGCTTGGCCACAGTCCTCTGCAGGTTTCGGAGATCTGCCTCGGCACCATGACGTTTGGTGAGCAGAA
TACCCAGACTGAGGCTTGGGAACAGCTCGATTACGCAGTAGAACACGGGATCAACTTCATCGATACGGCGGAGATGTACC
CGGTGCCGGCGCGGGCGGAAACCCAGGGAGCCACAGAACGCTACATCGGCGAGTGGCTGCAGCACCAGCCGCGGGAGCGC
CTTGTCATCGCCACCAAGATCACCGGCCCGGGGCGGCCCTGGCACTGGATCCGCGGCGGGTCTCTCTCGATTAGCCGCAA
CAACCTCAAACAGGCGGTGGCCGGCAGCCTCAAGCGCCTGAAAACCGACTACATCGACCTCTACCAAATCCACTGGCCGG
ATCGCTATGTGCCCCTGTTTGGGGGTGTGGCCTACGATCCCTCTCAAGAGCGGCCCACGGTTCCCATTGCCGAGCAACTG
CAGGGTCTGGCGGAACTGGTGCAGGAGGGCCTGGTGCGCTACATCGGCCTGAGCAACGAAACCCCTTGGGGAGTCTGCGA
GTTCTGCCACGTGGCCGAGCAGTTGGGCTTGCCCAGGGTAGTCTCGATTCAAAACGCCTATAGCCTCCTCAACCGCACCT
TTGAGATGGGGCTGGCGGAGGTCTGTCGCCACGAACAGGTAGGGCTGCTGGCCTACAGCCCCCTGGCCTTTGGGCTGCTG
ACGGGCAAATACCTGGGGGGCGCCAAGCCGCCGGGATCCCGTTTGGCCCTGTTCGAGGGCTTTGGCCAGCGCTACCGCAA
GCCCAATGTGGAAGAGGCCGTGGCTGCCTACGTGCGCATTGCCCGCCAGCACGGCCTGACCCCTGCCCAGTTGGCTTTGG
CCTTTGTGCGCAGCCGTTGGTTTGTCACCAGCACCATCATCGGGGCCACCAACCTGGCCCAGCTCAAGGAAAACCTCAGT
TGCCTCGAGGTGGAGCTGTCGCCTGCGATCCTGGCAGAAATTGAGGCGGTGCACCAGCGCTACCCCAATCCCGCCCCGTG
A

Upstream 100 bases:

>100_bases
TGTGCTGCAGCAAGAGTAGGGGCAGGGATCCCAGGGGCTGGCAAGTTTTGGGCACAATGGGGACTGGTGTGCTGTTTAGG
GTTGGAGACGGCAAGTTCCC

Downstream 100 bases:

>100_bases
AACTTCGGAAACCGATAGAACTTTTCAGGAGATTTTTTCGTTTAGGGTTACGGAGTGGGTAACTCCATCCGGCTCTTCTT
CGATTGTTGATTGTTTGGGC

Product: aldo/keto reductase Tas

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRYRQLGHSPLQVSEICLGTMTFGEQNTQTEAWEQLDYAVEHGINFIDTAEMYPVPARAETQGATERYIGEWLQHQPRER
LVIATKITGPGRPWHWIRGGSLSISRNNLKQAVAGSLKRLKTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQL
QGLAELVQEGLVRYIGLSNETPWGVCEFCHVAEQLGLPRVVSIQNAYSLLNRTFEMGLAEVCRHEQVGLLAYSPLAFGLL
TGKYLGGAKPPGSRLALFEGFGQRYRKPNVEEAVAAYVRIARQHGLTPAQLALAFVRSRWFVTSTIIGATNLAQLKENLS
CLEVELSPAILAEIEAVHQRYPNPAP

Sequences:

>Translated_346_residues
MRYRQLGHSPLQVSEICLGTMTFGEQNTQTEAWEQLDYAVEHGINFIDTAEMYPVPARAETQGATERYIGEWLQHQPRER
LVIATKITGPGRPWHWIRGGSLSISRNNLKQAVAGSLKRLKTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQL
QGLAELVQEGLVRYIGLSNETPWGVCEFCHVAEQLGLPRVVSIQNAYSLLNRTFEMGLAEVCRHEQVGLLAYSPLAFGLL
TGKYLGGAKPPGSRLALFEGFGQRYRKPNVEEAVAAYVRIARQHGLTPAQLALAFVRSRWFVTSTIIGATNLAQLKENLS
CLEVELSPAILAEIEAVHQRYPNPAP
>Mature_346_residues
MRYRQLGHSPLQVSEICLGTMTFGEQNTQTEAWEQLDYAVEHGINFIDTAEMYPVPARAETQGATERYIGEWLQHQPRER
LVIATKITGPGRPWHWIRGGSLSISRNNLKQAVAGSLKRLKTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQL
QGLAELVQEGLVRYIGLSNETPWGVCEFCHVAEQLGLPRVVSIQNAYSLLNRTFEMGLAEVCRHEQVGLLAYSPLAFGLL
TGKYLGGAKPPGSRLALFEGFGQRYRKPNVEEAVAAYVRIARQHGLTPAQLALAFVRSRWFVTSTIIGATNLAQLKENLS
CLEVELSPAILAEIEAVHQRYPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=354, Percent_Identity=31.638418079096, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI4504825, Length=352, Percent_Identity=31.5340909090909, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI27436971, Length=358, Percent_Identity=31.8435754189944, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI27436964, Length=355, Percent_Identity=29.5774647887324, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436962, Length=355, Percent_Identity=29.5774647887324, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI27436966, Length=355, Percent_Identity=29.2957746478873, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI41327764, Length=339, Percent_Identity=27.7286135693215, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI223718702, Length=348, Percent_Identity=27.2988505747126, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41152114, Length=246, Percent_Identity=28.8617886178862, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=55.9077809798271, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI87081735, Length=356, Percent_Identity=31.1797752808989, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1788070, Length=346, Percent_Identity=31.5028901734104, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=31.5028901734104, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788081, Length=331, Percent_Identity=29.9093655589124, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787674, Length=335, Percent_Identity=25.6716417910448, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786400, Length=289, Percent_Identity=28.3737024221453, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323998, Length=351, Percent_Identity=29.0598290598291, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319958, Length=322, Percent_Identity=28.8819875776398, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319951, Length=343, Percent_Identity=26.8221574344023, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325169, Length=345, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=266, Percent_Identity=27.0676691729323, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321052, Length=145, Percent_Identity=34.4827586206897, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640980, Length=378, Percent_Identity=26.4550264550265, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45549126, Length=374, Percent_Identity=26.2032085561497, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646159, Length=236, Percent_Identity=30.9322033898305, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=27.3273273273273, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38679; Mature: 38679

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRQLGHSPLQVSEICLGTMTFGEQNTQTEAWEQLDYAVEHGINFIDTAEMYPVPARAE
CCCHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCC
TQGATERYIGEWLQHQPRERLVIATKITGPGRPWHWIRGGSLSISRNNLKQAVAGSLKRL
CCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEECCCEEEECHHHHHHHHHHHHHHH
KTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQLQGLAELVQEGLVRYIGLSNE
HHHHEEEEEEECCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
TPWGVCEFCHVAEQLGLPRVVSIQNAYSLLNRTFEMGLAEVCRHEQVGLLAYSPLAFGLL
CCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHH
TGKYLGGAKPPGSRLALFEGFGQRYRKPNVEEAVAAYVRIARQHGLTPAQLALAFVRSRW
HHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FVTSTIIGATNLAQLKENLSCLEVELSPAILAEIEAVHQRYPNPAP
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRYRQLGHSPLQVSEICLGTMTFGEQNTQTEAWEQLDYAVEHGINFIDTAEMYPVPARAE
CCCHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCC
TQGATERYIGEWLQHQPRERLVIATKITGPGRPWHWIRGGSLSISRNNLKQAVAGSLKRL
CCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEECCCEEEECHHHHHHHHHHHHHHH
KTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQLQGLAELVQEGLVRYIGLSNE
HHHHEEEEEEECCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
TPWGVCEFCHVAEQLGLPRVVSIQNAYSLLNRTFEMGLAEVCRHEQVGLLAYSPLAFGLL
CCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHH
TGKYLGGAKPPGSRLALFEGFGQRYRKPNVEEAVAAYVRIARQHGLTPAQLALAFVRSRW
HHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FVTSTIIGATNLAQLKENLSCLEVELSPAILAEIEAVHQRYPNPAP
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]