Click here to switch to the map view.

The map label for this gene is clpX

Identifier: 86605508

GI number: 86605508

Start: 812563

End: 813909

Strand: Reverse

Name: clpX

Synonym: CYA_0802

Alternate gene names: 86605508

Gene position: 813909-812563 (Counterclockwise)

Preceding gene: 86605509

Following gene: 86605507

Centisome position: 27.75

GC content: 58.28

Gene sequence:

>1347_bases
ATGGCCAAGCATGACTCCCACCTGAGATGCTCCTTCTGTAATAAGTCCCAGGATCAAGTGCGTAAGTTGATTGCGGGGCC
GGGGGTCTACATCTGCGACGAGTGTGTGGAGCTGTGCAACGAGATTTTGGAGGAGGAACTCTACGACGGCAATACCCCAC
CTGCCACAGCCCCTGCTGCCAGCCGTCGCGAAACTCCTAGAAAATCCTCTCGCAGCTTGCCTTCTCTGGCACAGTTGCCT
AAGCCGCGCGAGATCATGCGCTACCTTGACCAGTACGTGATTGGCCAAGAGAAGGCCAAGAAGGTTCTGTCGGTGGCGGT
TTACAACCACTACAAGCGGCTGGCTGCTAAGGCCAACCCCAACAGCCTCGGAGCTGCGGAGCTGGATGAGGTGGAACTGC
AAAAGTCCAACATTTTGGTCATTGGCCCCACCGGCTCCGGCAAAACCCTGCTGGCCGAAACCCTGGCCCGCATGTTGGAT
GTGCCCTTTGCCGTTGCCGATGCCACTACCCTCACCGAAGCCGGCTACGTCGGCGAAGATGTGGAAAACATCCTGTTGCG
CCTGCTGCAGGTGGCGGACATGGATGTGGAAGAAGCCCAGCGCGGCATCATCTACATCGACGAAATCGACAAAATTGCCC
GCAAGAGCGAAAACCCTTCCATTACCCGCGACGTTTCCGGCGAAGGGGTGCAGCAGGCTTTGTTGAAGATGCTGGAGGGA
ACTATTGCCAACGTGCCTCCGCAGGGAGGGCGCAAGCACCCCTACCAAGACTGCATTCAAATCGACACTTCCAACATTCT
CTTCATCTGTGGGGGCGCTTTTGTCGGCCTGGAGAAGGTGATCGAGCAGCGCATTGGCAAAAAGTCGATGGGCTTTATCA
AGCCAGGGGAGCAGCTAGCAGTTACCCGTGAGCAACGCCTGGCCGATGCCCTCAAGGCGCTGGAGCCGGAGGATTTGATC
AAGTACGGCATGATCCCAGAATTCATAGGGCGGCTGCCGGTGGTGGCTACCCTGGATCCCCTGGACGAGAAGGCCCTCGA
GGCCATCTTGACGCAGCCTAAAAATGCCATCCTCAAGCAGGCCCAGAAGCTGTTGCGCATGGACGGGGTGGAGCTAGAGT
TCGAGCCGGCTGCCATTTCTGCCATTGCCAAGGAAGCCTACCGTCGCAAAACGGGGGCGCGGGCGCTGCGGGCCATTGTG
GAAGAGCTAATGCTGGACGTGATGTACGAGGTTCCCTCTCGCCGGGATATCAAATACGTGCGCATCACGGCCGAGATGGT
GGAGCGCCGTTCCACGCACGAGCTGATCCCTCACCCTTCCACCCTGCCTAAACCTGAGTCTGCCTAG

Upstream 100 bases:

>100_bases
CTCTGCGGCCGCGCCCCACGTTTAAGCAGCACCAGAGCGTCCTGTCTTTCCTGGAATTCGCCGAACACAATAGCCAAGAG
CAAACAGCAACGAGGATCCC

Downstream 100 bases:

>100_bases
GGTCACAGCCCTGCTGGATCCCGCTGCGTCGGCATATGATCAGTGTTTGGTCTTGCAAGGAAGGGCAAGGGGGCGCATGG
GGCGGGCGGATCGCGAGTAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MAKHDSHLRCSFCNKSQDQVRKLIAGPGVYICDECVELCNEILEEELYDGNTPPATAPAASRRETPRKSSRSLPSLAQLP
KPREIMRYLDQYVIGQEKAKKVLSVAVYNHYKRLAAKANPNSLGAAELDEVELQKSNILVIGPTGSGKTLLAETLARMLD
VPFAVADATTLTEAGYVGEDVENILLRLLQVADMDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
TIANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVIEQRIGKKSMGFIKPGEQLAVTREQRLADALKALEPEDLI
KYGMIPEFIGRLPVVATLDPLDEKALEAILTQPKNAILKQAQKLLRMDGVELEFEPAAISAIAKEAYRRKTGARALRAIV
EELMLDVMYEVPSRRDIKYVRITAEMVERRSTHELIPHPSTLPKPESA

Sequences:

>Translated_448_residues
MAKHDSHLRCSFCNKSQDQVRKLIAGPGVYICDECVELCNEILEEELYDGNTPPATAPAASRRETPRKSSRSLPSLAQLP
KPREIMRYLDQYVIGQEKAKKVLSVAVYNHYKRLAAKANPNSLGAAELDEVELQKSNILVIGPTGSGKTLLAETLARMLD
VPFAVADATTLTEAGYVGEDVENILLRLLQVADMDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
TIANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVIEQRIGKKSMGFIKPGEQLAVTREQRLADALKALEPEDLI
KYGMIPEFIGRLPVVATLDPLDEKALEAILTQPKNAILKQAQKLLRMDGVELEFEPAAISAIAKEAYRRKTGARALRAIV
EELMLDVMYEVPSRRDIKYVRITAEMVERRSTHELIPHPSTLPKPESA
>Mature_447_residues
AKHDSHLRCSFCNKSQDQVRKLIAGPGVYICDECVELCNEILEEELYDGNTPPATAPAASRRETPRKSSRSLPSLAQLPK
PREIMRYLDQYVIGQEKAKKVLSVAVYNHYKRLAAKANPNSLGAAELDEVELQKSNILVIGPTGSGKTLLAETLARMLDV
PFAVADATTLTEAGYVGEDVENILLRLLQVADMDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGT
IANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVIEQRIGKKSMGFIKPGEQLAVTREQRLADALKALEPEDLIK
YGMIPEFIGRLPVVATLDPLDEKALEAILTQPKNAILKQAQKLLRMDGVELEFEPAAISAIAKEAYRRKTGARALRAIVE
ELMLDVMYEVPSRRDIKYVRITAEMVERRSTHELIPHPSTLPKPESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=441, Percent_Identity=43.0839002267574, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI1786642, Length=431, Percent_Identity=60.7888631090487, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1790366, Length=114, Percent_Identity=39.4736842105263, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71988663, Length=410, Percent_Identity=39.5121951219512, Blast_Score=267, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI71982908, Length=305, Percent_Identity=43.2786885245902, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=305, Percent_Identity=43.2786885245902, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=39.4422310756972, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=430, Percent_Identity=39.5348837209302, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24648291, Length=332, Percent_Identity=45.7831325301205, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24648289, Length=332, Percent_Identity=45.7831325301205, Blast_Score=286, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_SYNJA (Q2JW64)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474271.1
- ProteinModelPortal:   Q2JW64
- STRING:   Q2JW64
- GeneID:   3898185
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0802
- TIGR:   CYA_0802
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   SSP321327:CYA_0802-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 49588; Mature: 49457

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHDSHLRCSFCNKSQDQVRKLIAGPGVYICDECVELCNEILEEELYDGNTPPATAPAA
CCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SRRETPRKSSRSLPSLAQLPKPREIMRYLDQYVIGQEKAKKVLSVAVYNHYKRLAAKANP
HHCCCCCHHHCCCCHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCC
NSLGAAELDEVELQKSNILVIGPTGSGKTLLAETLARMLDVPFAVADATTLTEAGYVGED
CCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHH
VENILLRLLQVADMDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
HHHHHHHHHHHHCCCHHHHHCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
TIANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVIEQRIGKKSMGFIKPGEQLA
HHHCCCCCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
VTREQRLADALKALEPEDLIKYGMIPEFIGRLPVVATLDPLDEKALEAILTQPKNAILKQ
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCCCEEECCCCHHHHHHHHHHCCHHHHHHH
AQKLLRMDGVELEFEPAAISAIAKEAYRRKTGARALRAIVEELMLDVMYEVPSRRDIKYV
HHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
RITAEMVERRSTHELIPHPSTLPKPESA
EEEHHHHHCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKHDSHLRCSFCNKSQDQVRKLIAGPGVYICDECVELCNEILEEELYDGNTPPATAPAA
CCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SRRETPRKSSRSLPSLAQLPKPREIMRYLDQYVIGQEKAKKVLSVAVYNHYKRLAAKANP
HHCCCCCHHHCCCCHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCC
NSLGAAELDEVELQKSNILVIGPTGSGKTLLAETLARMLDVPFAVADATTLTEAGYVGED
CCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHH
VENILLRLLQVADMDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
HHHHHHHHHHHHCCCHHHHHCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
TIANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVIEQRIGKKSMGFIKPGEQLA
HHHCCCCCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
VTREQRLADALKALEPEDLIKYGMIPEFIGRLPVVATLDPLDEKALEAILTQPKNAILKQ
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCCCEEECCCCHHHHHHHHHHCCHHHHHHH
AQKLLRMDGVELEFEPAAISAIAKEAYRRKTGARALRAIVEELMLDVMYEVPSRRDIKYV
HHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
RITAEMVERRSTHELIPHPSTLPKPESA
EEEHHHHHCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA