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The map label for this gene is ndhA

Identifier: 86605455

GI number: 86605455

Start: 753577

End: 754698

Strand: Reverse

Name: ndhA

Synonym: CYA_0745

Alternate gene names: 86605455

Gene position: 754698-753577 (Counterclockwise)

Preceding gene: 86605456

Following gene: 86605454

Centisome position: 25.73

GC content: 58.38

Gene sequence:

>1122_bases
ATGACAACCGCCGGCATTGACCTACAGCTTGGTTTTGAAACAGCCCTGCAAAACTTGGGCCTGAGCCCAGGCGCTGCCCA
CGCTTTGTGGGTACCTTTGCCCATGTTGCTCATGGTCATCGCCGCCACCTTAGGAGTGATGGTCATGACCTGGCTAGAGC
GGAAGATCTCGGCGGCGGCCCAGCAGCGGATTGGCCCCAACATGGCCGGGCCACAGGGGGTACTGATCCCGATTGCCGAT
GGCATCAAGCTCTTGACGAAGGAAGATGTGCTGCCCAGCTTGGCCGACCCAGTTTTGTTCACGCTGGGGCCGATCCTGGT
TTTCCTGCCGGTCTTTTTGTGTTATCTGGTGGTTCCCTTCGGCCAGAACCTATTGATCTCCAACATCGCCATCGGGGTGT
TTTTCTTGATCGCCACCTCCAGCGTGCAGCCCATCGGCCTGTTGATGTCGGGCTACGGCTCCAACAACAAGTATTCTCTG
CTGGGGGGGCTGCGGGCGGCGGCCCAGTCAATTAGCTACGAACTGCCCTTGGCCTTGTCGGTGCTGGCGGTGGTGCTGAT
GAGCAACGGCCTGGACACCGTGGGGATCGTGGAGCAGCAGAGTGGGCTGGGGATCCTCAGTTGGAACGTGTGGCGGCAGC
CGATTGGCTTTGTCATTTTCCTGATCTCGGCGCTGGCGGAAACCGAACGGATCCCCTTTGATTTGCCGGAAGCCGAAGAG
GAGCTGGTGGCCGGCTACCAGACGGAGTACTCCGGCATGAAATTTGCCCTGTTTTACCTGGGATCCTACGCCAACTTGCT
GCTGGCCTCTCTCATTGCGGCGGTGTTGTACTTGGGCGGCTGGTCGTTTGTGGTGCCGGTGGAAACAATTGCCGCCTGGC
TCGGGATCCCGTTGGACAACCCCTTTTTGCAGATCGGCGCGGCGGTGTTGGGCATTCTCATGACGATGGTCAAGGCTTTT
ATCTTTGTGTTTTTGGCCATCCTCTTGCGCTGGACCCTGCCGCGGGTGCGCATTGACCAGCTGTTGGATTTGGGGTGGAA
ATTTCTGCTGCCCGTCTCGTTTGTGAATTTGCTGTTGACGGCGGCTTTGAAGCTGGCCTTCCCAACCTTTTTCGGGGGTT
AA

Upstream 100 bases:

>100_bases
CACCGTCCCCCTCAGTCGGATCCCAACGGCAAAGCCTAGTTAGATCCACAGACTCCAGTGCCTTTTTTGACTCACCGTCT
CTAGGGAGCCACTCAACCCC

Downstream 100 bases:

>100_bases
TGAAAGTAGAAGCAGCAAGGGAGAGGAAATAGGTCATGACTTTTCTAAAGCGCGTTGGCGAATACGTAAGCGATGCCTTC
AAGGCTGCTAAGTACATTGG

Product: NADH dehydrogenase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit 1; NDH-1 subunit 1; NDH-A

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTTAGIDLQLGFETALQNLGLSPGAAHALWVPLPMLLMVIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIAD
GIKLLTKEDVLPSLADPVLFTLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIATSSVQPIGLLMSGYGSNNKYSL
LGGLRAAAQSISYELPLALSVLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEE
ELVAGYQTEYSGMKFALFYLGSYANLLLASLIAAVLYLGGWSFVVPVETIAAWLGIPLDNPFLQIGAAVLGILMTMVKAF
IFVFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG

Sequences:

>Translated_373_residues
MTTAGIDLQLGFETALQNLGLSPGAAHALWVPLPMLLMVIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIAD
GIKLLTKEDVLPSLADPVLFTLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIATSSVQPIGLLMSGYGSNNKYSL
LGGLRAAAQSISYELPLALSVLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEE
ELVAGYQTEYSGMKFALFYLGSYANLLLASLIAAVLYLGGWSFVVPVETIAAWLGIPLDNPFLQIGAAVLGILMTMVKAF
IFVFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG
>Mature_372_residues
TTAGIDLQLGFETALQNLGLSPGAAHALWVPLPMLLMVIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIADG
IKLLTKEDVLPSLADPVLFTLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIATSSVQPIGLLMSGYGSNNKYSLL
GGLRAAAQSISYELPLALSVLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEEE
LVAGYQTEYSGMKFALFYLGSYANLLLASLIAAVLYLGGWSFVVPVETIAAWLGIPLDNPFLQIGAAVLGILMTMVKAFI
FVFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

Organism=Homo sapiens, GI251831107, Length=301, Percent_Identity=34.21926910299, Blast_Score=165, Evalue=7e-41,
Organism=Escherichia coli, GI1788618, Length=331, Percent_Identity=37.4622356495468, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU1C_SYNJA (Q2JWB3)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474218.1
- STRING:   Q2JWB3
- GeneID:   3897082
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0745
- TIGR:   CYA_0745
- eggNOG:   COG1005
- HOGENOM:   HBG727670
- OMA:   IFWICAL
- ProtClustDB:   PRK06076
- BioCyc:   SSP321327:CYA_0745-MONOMER
- HAMAP:   MF_01350
- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: 1.6.5.3

Molecular weight: Translated: 40153; Mature: 40021

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00667 COMPLEX1_ND1_1; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x134f887c)-; HASH(0x13ec73f4)-; HASH(0x13525af0)-; HASH(0x13ec72e0)-; HASH(0x13ea8ba0)-; HASH(0x13ea34e0)-; HASH(0x120f1f24)-; HASH(0x13ed3ea8)-; HASH(0x13ea8a2c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAGIDLQLGFETALQNLGLSPGAAHALWVPLPMLLMVIAATLGVMVMTWLERKISAAA
CCCCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRIGPNMAGPQGVLIPIADGIKLLTKEDVLPSLADPVLFTLGPILVFLPVFLCYLVVPF
HHHCCCCCCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQNLLISNIAIGVFFLIATSSVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALS
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHH
VLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEE
HHHHHHHHCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ELVAGYQTEYSGMKFALFYLGSYANLLLASLIAAVLYLGGWSFVVPVETIAAWLGIPLDN
HHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCC
PFLQIGAAVLGILMTMVKAFIFVFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
AALKLAFPTFFGG
HHHHHHHHHHCCH
>Mature Secondary Structure 
TTAGIDLQLGFETALQNLGLSPGAAHALWVPLPMLLMVIAATLGVMVMTWLERKISAAA
CCCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRIGPNMAGPQGVLIPIADGIKLLTKEDVLPSLADPVLFTLGPILVFLPVFLCYLVVPF
HHHCCCCCCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQNLLISNIAIGVFFLIATSSVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALS
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHH
VLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEE
HHHHHHHHCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ELVAGYQTEYSGMKFALFYLGSYANLLLASLIAAVLYLGGWSFVVPVETIAAWLGIPLDN
HHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCC
PFLQIGAAVLGILMTMVKAFIFVFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
AALKLAFPTFFGG
HHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA