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The map label for this gene is ndhI

Identifier: 86605454

GI number: 86605454

Start: 752909

End: 753541

Strand: Reverse

Name: ndhI

Synonym: CYA_0744

Alternate gene names: 86605454

Gene position: 753541-752909 (Counterclockwise)

Preceding gene: 86605455

Following gene: 86605450

Centisome position: 25.69

GC content: 54.03

Gene sequence:

>633_bases
ATGACTTTTCTAAAGCGCGTTGGCGAATACGTAAGCGATGCCTTCAAGGCTGCTAAGTACATTGGCCAGGGGATGGGGGT
CGTCTTCGACCACATGAACCGCCGGCCCGTGACTGTTCAGTACCCCTTTGAGAAGCTGATCCCTTCCGAGCGCTTTCGGG
GACGCATTCACTTTGAGTTCGATAAGTGCATTGCCTGCGAGATCTGTGTTCGGGTTTGCCCCATCGACCTGCCCGTGGTG
GACTGGGTCTACAACACCGAGCTGAAGAAAAAAGAGCTCTACAGCTACAGCATCGATTTTGGAGTATGCATTTTCTGCGC
CAACTGCGTAGAGTTTTGCCCCACCAATTGCCTCTCGGTTACCGAAGATTATGAGCTAGCCACCTACGACCGCCACGAGC
TGAACTACCATCAGGTGGCGCTAGGTCGCCTGCCTTCCAAAGTAACAGAGGATCCAATGGTGACACCTCTACGGGAGTTT
GCCTACCTGCCCAAGGGGGTGATCGATCCCCACGACCTGCCTACCGGATCCCAGCGAGCTGGGAAGCGACCCGAAGAGAT
TTTGGCAGAGATGAGAGCGGCTAAAGCAGCAGAAGCAAAAGAGGACAAAACTGCTGCAGAGCAGTCTAACTAA

Upstream 100 bases:

>100_bases
CGTTTGTGAATTTGCTGTTGACGGCGGCTTTGAAGCTGGCCTTCCCAACCTTTTTCGGGGGTTAATGAAAGTAGAAGCAG
CAAGGGAGAGGAAATAGGTC

Downstream 100 bases:

>100_bases
TAGGCATAGGCAGCTCTCTTGAGTAGTTGACAAGACGCCTTCTTCACTCCAAGAGGTTTGGGCCCAGGCTAATTCCCTCT
CTTTGTTGCCGTTCTTGTTT

Product: NADH dehydrogenase subunit I

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit I; NDH-1 subunit I; NDH-I

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTFLKRVGEYVSDAFKAAKYIGQGMGVVFDHMNRRPVTVQYPFEKLIPSERFRGRIHFEFDKCIACEICVRVCPIDLPVV
DWVYNTELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSVTEDYELATYDRHELNYHQVALGRLPSKVTEDPMVTPLREF
AYLPKGVIDPHDLPTGSQRAGKRPEEILAEMRAAKAAEAKEDKTAAEQSN

Sequences:

>Translated_210_residues
MTFLKRVGEYVSDAFKAAKYIGQGMGVVFDHMNRRPVTVQYPFEKLIPSERFRGRIHFEFDKCIACEICVRVCPIDLPVV
DWVYNTELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSVTEDYELATYDRHELNYHQVALGRLPSKVTEDPMVTPLREF
AYLPKGVIDPHDLPTGSQRAGKRPEEILAEMRAAKAAEAKEDKTAAEQSN
>Mature_209_residues
TFLKRVGEYVSDAFKAAKYIGQGMGVVFDHMNRRPVTVQYPFEKLIPSERFRGRIHFEFDKCIACEICVRVCPIDLPVVD
WVYNTELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSVTEDYELATYDRHELNYHQVALGRLPSKVTEDPMVTPLREFA
YLPKGVIDPHDLPTGSQRAGKRPEEILAEMRAAKAAEAKEDKTAAEQSN

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Homo sapiens, GI4505371, Length=124, Percent_Identity=31.4516129032258, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788617, Length=111, Percent_Identity=34.2342342342342, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789075, Length=98, Percent_Identity=33.6734693877551, Blast_Score=66, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555194, Length=124, Percent_Identity=32.258064516129, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864306, Length=139, Percent_Identity=29.4964028776978, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NDHI_SYNJA (Q2JWB4)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474217.1
- ProteinModelPortal:   Q2JWB4
- SMR:   Q2JWB4
- STRING:   Q2JWB4
- GeneID:   3897081
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0744
- TIGR:   CYA_0744
- eggNOG:   COG1143
- HOGENOM:   HBG724359
- OMA:   HYSIDFG
- ProtClustDB:   PRK05888
- BioCyc:   SSP321327:CYA_0744-MONOMER
- HAMAP:   MF_01351
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR004497
- InterPro:   IPR010226
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR00403
- TIGRFAMs:   TIGR01971

Pfam domain/function: NA

EC number: 1.6.5.3

Molecular weight: Translated: 23959; Mature: 23828

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLKRVGEYVSDAFKAAKYIGQGMGVVFDHMNRRPVTVQYPFEKLIPSERFRGRIHFEF
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEECCHHHCCCCHHHCCEEEEEH
DKCIACEICVRVCPIDLPVVDWVYNTELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSV
HHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
TEDYELATYDRHELNYHQVALGRLPSKVTEDPMVTPLREFAYLPKGVIDPHDLPTGSQRA
CCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHC
GKRPEEILAEMRAAKAAEAKEDKTAAEQSN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TFLKRVGEYVSDAFKAAKYIGQGMGVVFDHMNRRPVTVQYPFEKLIPSERFRGRIHFEF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEECCHHHCCCCHHHCCEEEEEH
DKCIACEICVRVCPIDLPVVDWVYNTELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSV
HHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
TEDYELATYDRHELNYHQVALGRLPSKVTEDPMVTPLREFAYLPKGVIDPHDLPTGSQRA
CCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHC
GKRPEEILAEMRAAKAAEAKEDKTAAEQSN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA