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The map label for this gene is coaE

Identifier: 86605281

GI number: 86605281

Start: 578722

End: 579414

Strand: Reverse

Name: coaE

Synonym: CYA_0565

Alternate gene names: 86605281

Gene position: 579414-578722 (Counterclockwise)

Preceding gene: 86605282

Following gene: 86605280

Centisome position: 19.76

GC content: 65.95

Gene sequence:

>693_bases
ATGAGAATCATCGGCCTGACGGGCGGCATAGCCACAGGCAAATCCACGGTGGCCCGCATCTTGGAACGGCACGGGATCCC
GGTGGCCGATGCAGATCAGATGGCGCGGCAAGCCCTAGCGGTGGGATCCCCCATCCGCGAGCGGGTGCTGCAGCGCTACG
GCCGGGCCATCCAGGATCCCTCTGGAGCGCTGGATCGCCGCCAGTTGGGGCGGATTGTCTTTGCCGATGCCGCCGAGCGG
GCCTGGCTGGAAGCCCAGATCCATCCTTTTGTCAAAGCGCGGCTGCGGGAGTTTCTCGAGGCCCACGGGGCATCTGCGCC
GCCTGAGGAAGCGACTGAGGCTCGACCCAGTTGCCAATGTCCTCACGGGGAAGGCCATCCCACCGTTTGCCTGATGATCC
CGCTCCTGTTTGAGGCCCACATGGAAAACTGGGCCAGCGAGATCTGGGTGGTGACCTGTACCCCGGAGCAGCAGCGGCAG
CGGCTGGCGCAGCGGGATCTGCTGACGGCGGCAGAAATCGAGGCGCGCCTGGCCAGCCAGTGGCCCCTAGAAGAAAAGGC
CCGTCGCGCCCATGTAGTGCTGGACAATTCCGGATCCCTGGCGCAGCTGGAAGCCCAGGTTAGGCAAGCCCTGGGGGCTC
ACCCCAGAGAAGGAGGGGCCATTTGCCCCACCCCGCCGAGCCGGATAGAGTGA

Upstream 100 bases:

>100_bases
AAGGGGATCTCCCCTCTCCCTCTGGGAGAGGGGCTGGGGGTGAGGGCCGGCGCGGAGCGCTTGGGCCTGTCTCCAACTCA
TTTGAAATCACCCAGCTCCC

Downstream 100 bases:

>100_bases
CGGGGGAGGGATCCCTTTCTTTGCAGCTATGTCTGGATGGATCGAGAAAGAGGCGATGCAGGAAGCACTTTGTGGCAGCG
GGAGAGAGTCTTTGTGGACC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRIIGLTGGIATGKSTVARILERHGIPVADADQMARQALAVGSPIRERVLQRYGRAIQDPSGALDRRQLGRIVFADAAER
AWLEAQIHPFVKARLREFLEAHGASAPPEEATEARPSCQCPHGEGHPTVCLMIPLLFEAHMENWASEIWVVTCTPEQQRQ
RLAQRDLLTAAEIEARLASQWPLEEKARRAHVVLDNSGSLAQLEAQVRQALGAHPREGGAICPTPPSRIE

Sequences:

>Translated_230_residues
MRIIGLTGGIATGKSTVARILERHGIPVADADQMARQALAVGSPIRERVLQRYGRAIQDPSGALDRRQLGRIVFADAAER
AWLEAQIHPFVKARLREFLEAHGASAPPEEATEARPSCQCPHGEGHPTVCLMIPLLFEAHMENWASEIWVVTCTPEQQRQ
RLAQRDLLTAAEIEARLASQWPLEEKARRAHVVLDNSGSLAQLEAQVRQALGAHPREGGAICPTPPSRIE
>Mature_230_residues
MRIIGLTGGIATGKSTVARILERHGIPVADADQMARQALAVGSPIRERVLQRYGRAIQDPSGALDRRQLGRIVFADAAER
AWLEAQIHPFVKARLREFLEAHGASAPPEEATEARPSCQCPHGEGHPTVCLMIPLLFEAHMENWASEIWVVTCTPEQQRQ
RLAQRDLLTAAEIEARLASQWPLEEKARRAHVVLDNSGSLAQLEAQVRQALGAHPREGGAICPTPPSRIE

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=213, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI191252795, Length=213, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI205277394, Length=196, Percent_Identity=27.0408163265306, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI110227605, Length=196, Percent_Identity=27.0408163265306, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI110227603, Length=196, Percent_Identity=27.0408163265306, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI110227601, Length=196, Percent_Identity=27.0408163265306, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI110227607, Length=196, Percent_Identity=27.0408163265306, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1786292, Length=197, Percent_Identity=33.502538071066, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17554944, Length=214, Percent_Identity=31.7757009345794, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI25143409, Length=210, Percent_Identity=27.6190476190476, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=212, Percent_Identity=29.2452830188679, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644728, Length=206, Percent_Identity=33.9805825242718, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24658602, Length=192, Percent_Identity=31.25, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_SYNJA (Q2JWS5)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474044.1
- ProteinModelPortal:   Q2JWS5
- SMR:   Q2JWS5
- STRING:   Q2JWS5
- GeneID:   3897401
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0565
- TIGR:   CYA_0565
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   ERIWLEN
- ProtClustDB:   PRK14730
- BioCyc:   SSP321327:CYA_0565-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 25267; Mature: 25267

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIGLTGGIATGKSTVARILERHGIPVADADQMARQALAVGSPIRERVLQRYGRAIQDP
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
SGALDRRQLGRIVFADAAERAWLEAQIHPFVKARLREFLEAHGASAPPEEATEARPSCQC
CCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC
PHGEGHPTVCLMIPLLFEAHMENWASEIWVVTCTPEQQRQRLAQRDLLTAAEIEARLASQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
WPLEEKARRAHVVLDNSGSLAQLEAQVRQALGAHPREGGAICPTPPSRIE
CCHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIIGLTGGIATGKSTVARILERHGIPVADADQMARQALAVGSPIRERVLQRYGRAIQDP
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
SGALDRRQLGRIVFADAAERAWLEAQIHPFVKARLREFLEAHGASAPPEEATEARPSCQC
CCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCC
PHGEGHPTVCLMIPLLFEAHMENWASEIWVVTCTPEQQRQRLAQRDLLTAAEIEARLASQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
WPLEEKARRAHVVLDNSGSLAQLEAQVRQALGAHPREGGAICPTPPSRIE
CCHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA