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The map label for this gene is ahpC [C]

Identifier: 86605254

GI number: 86605254

Start: 552727

End: 553335

Strand: Reverse

Name: ahpC [C]

Synonym: CYA_0537

Alternate gene names: 86605254

Gene position: 553335-552727 (Counterclockwise)

Preceding gene: 86605257

Following gene: 86605252

Centisome position: 18.87

GC content: 60.26

Gene sequence:

>609_bases
ATGTCTCAGGAAGGATGTCTGCGGGTGGGGCAGCCCGCTCCCGATTTTTCGGCCACTGCCGTTTACGACATGGAATTTAA
GACGGTGAGGCTCTCCGACTACCGGGGCAAGAAGTACGTGGTGCTGTTCTTCTACCCCTTGGACTTCACCTTCGTCTGCC
CGACGGAGATCACGGCTTTCAGCGATCGCTACGACGAGTTTGCCAAGCTGGACACGGAGATCCTCGGCGTCTCGGTGGAT
AGCGAGTACTCTCACCTGGCCTGGATTCAGACCGACCGCAAAGCCGGAGGGGTGGGCGAGCTGAGGTATCCGCTGGTCTC
CGACCTGAAAAAGGAGATCAGCGCCGCCTACAATGTCCTGGATCCGGCGGCAGGGGTGGCTTTGCGCGGCCTGTTCATCA
TCGACAAGGAAGGGATCATCCAGCACGCCACCATCAACAACCTGGCCTTTGGCCGCAGCGTGGATGAAACCCTGCGCACC
CTGCAGGCCATCCAGTACGTGCAAGCTCACCCCGATGAAGTTTGCCCGGCCAACTGGCAGCCCGGCCAGAGAACCCTGAA
CCCCGACCCGGTGAAATCCAAGGAGTTCTTCGCGGCGGTTGCCAAGTAG

Upstream 100 bases:

>100_bases
GCGGCGCTCCAGCTTAGCCAGCCAGTAAGACAAAGTCATTATGAGTATGGTATGTTAGGTTTAGTTTACATTTGTACTTT
ACCGTAAGGAGCGTCGACTG

Downstream 100 bases:

>100_bases
GCTTGTCCAGGCCCTGTCAGGGATCCCGGGTTTTGACACTCCCCCGCCTGAAGGCGGGGGATTCTCACGTAGTCCATAAA
CGGACTCGTAAAGGCGCTGT

Product: anti-oxidant AhpCTSA family protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSQEGCLRVGQPAPDFSATAVYDMEFKTVRLSDYRGKKYVVLFFYPLDFTFVCPTEITAFSDRYDEFAKLDTEILGVSVD
SEYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVLDPAAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRT
LQAIQYVQAHPDEVCPANWQPGQRTLNPDPVKSKEFFAAVAK

Sequences:

>Translated_202_residues
MSQEGCLRVGQPAPDFSATAVYDMEFKTVRLSDYRGKKYVVLFFYPLDFTFVCPTEITAFSDRYDEFAKLDTEILGVSVD
SEYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVLDPAAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRT
LQAIQYVQAHPDEVCPANWQPGQRTLNPDPVKSKEFFAAVAK
>Mature_201_residues
SQEGCLRVGQPAPDFSATAVYDMEFKTVRLSDYRGKKYVVLFFYPLDFTFVCPTEITAFSDRYDEFAKLDTEILGVSVDS
EYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVLDPAAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRTL
QAIQYVQAHPDEVCPANWQPGQRTLNPDPVKSKEFFAAVAK

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=59.2783505154639, Blast_Score=239, Evalue=8e-64,
Organism=Homo sapiens, GI4505591, Length=195, Percent_Identity=57.4358974358974, Blast_Score=235, Evalue=2e-62,
Organism=Homo sapiens, GI32455266, Length=195, Percent_Identity=57.4358974358974, Blast_Score=235, Evalue=2e-62,
Organism=Homo sapiens, GI32455264, Length=195, Percent_Identity=57.4358974358974, Blast_Score=235, Evalue=2e-62,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=57.8125, Blast_Score=231, Evalue=4e-61,
Organism=Homo sapiens, GI32483377, Length=188, Percent_Identity=57.9787234042553, Blast_Score=228, Evalue=3e-60,
Organism=Homo sapiens, GI5453549, Length=190, Percent_Identity=55.7894736842105, Blast_Score=225, Evalue=2e-59,
Organism=Homo sapiens, GI33188454, Length=91, Percent_Identity=67.032967032967, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI4758638, Length=192, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=6e-17,
Organism=Escherichia coli, GI1786822, Length=173, Percent_Identity=35.8381502890173, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32565831, Length=189, Percent_Identity=56.6137566137566, Blast_Score=218, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193204376, Length=189, Percent_Identity=56.6137566137566, Blast_Score=218, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17554494, Length=189, Percent_Identity=50.7936507936508, Blast_Score=205, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI25153706, Length=190, Percent_Identity=27.3684210526316, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=195, Percent_Identity=49.7435897435897, Blast_Score=181, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6320661, Length=190, Percent_Identity=48.9473684210526, Blast_Score=179, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6319407, Length=203, Percent_Identity=31.0344827586207, Blast_Score=101, Evalue=7e-23,
Organism=Drosophila melanogaster, GI17738015, Length=196, Percent_Identity=59.1836734693878, Blast_Score=240, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24656348, Length=190, Percent_Identity=56.3157894736842, Blast_Score=224, Evalue=4e-59,
Organism=Drosophila melanogaster, GI17864676, Length=190, Percent_Identity=56.3157894736842, Blast_Score=224, Evalue=4e-59,
Organism=Drosophila melanogaster, GI17157991, Length=194, Percent_Identity=53.0927835051546, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24641739, Length=194, Percent_Identity=53.0927835051546, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=48.1675392670157, Blast_Score=194, Evalue=4e-50,
Organism=Drosophila melanogaster, GI17975518, Length=189, Percent_Identity=32.8042328042328, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24652434, Length=189, Percent_Identity=32.8042328042328, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24652436, Length=189, Percent_Identity=32.8042328042328, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24581278, Length=195, Percent_Identity=27.6923076923077, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22565; Mature: 22434

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEGCLRVGQPAPDFSATAVYDMEFKTVRLSDYRGKKYVVLFFYPLDFTFVCPTEITAF
CCCCCCEECCCCCCCCCCEEEEEEEEEEEEEECCCCCEEEEEEEECCCEEEECCCHHHHH
SDRYDEFAKLDTEILGVSVDSEYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVL
HHHHHHHHHHCHHHEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHC
DPAAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRTLQAIQYVQAHPDEVCPANWQ
CCCCHHHEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGQRTLNPDPVKSKEFFAAVAK
CCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SQEGCLRVGQPAPDFSATAVYDMEFKTVRLSDYRGKKYVVLFFYPLDFTFVCPTEITAF
CCCCCEECCCCCCCCCCEEEEEEEEEEEEEECCCCCEEEEEEEECCCEEEECCCHHHHH
SDRYDEFAKLDTEILGVSVDSEYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVL
HHHHHHHHHHCHHHEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHC
DPAAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRTLQAIQYVQAHPDEVCPANWQ
CCCCHHHEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGQRTLNPDPVKSKEFFAAVAK
CCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]