Click here to switch to the map view.

The map label for this gene is speA

Identifier: 86604858

GI number: 86604858

Start: 119962

End: 121887

Strand: Reverse

Name: speA

Synonym: CYA_0128

Alternate gene names: 86604858

Gene position: 121887-119962 (Counterclockwise)

Preceding gene: 86604862

Following gene: 86604854

Centisome position: 4.16

GC content: 63.19

Gene sequence:

>1926_bases
ATGCCGACTTTGACTCGTTCTCCCTGGACACTGCGAGACAGCGAAAAGCTCTATCGCATCTCAGGTTGGGGGGATCCCTA
CTTCCGTATCAACGCCGCCGGTCATGTGGAGGTAACCCCACAGGGCTCACAGCAGCAGGAAGGGGGCATCGACCTGTACC
ACCTGGTAACGGATCTGGTGGCGCGGGGTTTGCAGTTGCCTTTGTTGATTCGCTTTCCCGAGATCGTGGCCGACCGCATG
CGGCGGATTTGTGAGAGCTTTCAGCAGGCCATCGAGCGCTTTGGCTACCCCAACGTCTACCGAGGGGTTTACCCGGTCAA
GGTGAACCAGCAGCGCCACCTGGTGGAAGAGGTGGTCAAGCACGGCCGTGCCTACCACTTTGGCCTGGAGGCGGGATCCA
AGCCGGAGCTGTTGATCGCCCTGGCTCTGCTGGATACACCTGGGGCTTTGTTGATCTGCAACGGCTACAAAGACCGCGAC
TTTATGGAAACGGCCCTCTTGGCCCAGCGGCTGGGGCGCACCCCCATCATCGTCCTGGAACGGCTGCAAGAGCTGGAGCT
GGTGCTGCAAGCTGCCGAGCACCTGGGGATTGATCCCCTGCTGGGGGTGCGGGCCAAGCTGTCCGCCCAGGGCAGTGGCC
GCTGGGGCACCTCGGCTGGGGATCGGGGCAAGTTCGGCCTCACGGCCACCGAGATGTTGCAGGTGGTGGAGCGGCTGCGG
GAAGTCGGCAAGCTGCACTGTCTGCGCCTGTTGCACTACCACATCGGCTCGCAGATCTCGATGGTGAGCGTGCATGGGCG
GGCCGTGCGGGAGGCCAGCCAGATCTACATCGAGCTGGTCAAGCTGGGGGCGCCGATGGGCTATCTGGATGTCGGCGGCG
GCTTGGGGGTCGATTACGACGGATCCCAGTCCACCAGCCACTTTTCCCAGAGCTACAGCCTGGAAGATTACGCCGCCACC
GTGGTGCAGACGGTGCTGACCGCCCTGCAGCCGCACGGGATCCAGCCGCCGGTGCTGGTGACCGAAAGCGGGCGGGCCCT
GATGTCCCACCAGTCGGTGCTGGTCTTCGACATCCAGGATGTCAACGCCGCCAGCCCCTACCCCATGCCCACCCAGCTCA
CCTCCGATGCTGAGGTGATCCAAAAGCTGAACCAGCTCTACTACGAGATCCGGCCCGAGACCCTGGTGGCCGACTATCGC
CGCTGCCAGGAGCTGAAAGAGGCCGCCCTGCGCCAATTTACCGAGGGATCCCTCAGCTTGCGGGAGCGGGCCGAGGTGGA
GCGGCTGTTTTGGAACTGCTCCGACAAGATCTGCACGCTGGCCTACGAGCAGCACCAGGCGGGGCAGCCGGTGGCCGTAG
ATCTCCTGGATCTGGACGAGATGCTGGCCAGCATCTACTACGGCAACTTCTCCCTCTTCCAATCCCTGCCGGATAGCTGG
GCCATCGACCAGGTGTTCCCCATCATGCCCATCCACCGTCTGGACGAGGAGCCGCGCCAGTGGGCCACCCTGGCCGATCT
GACCTGCGACAGCGACGGCAAGATCAACCGCTTCTTTGGCGAAGACGGGCAGATCACCTCGGTTTTGCCGCTGCACGATC
CCAACGGGCAGCCCTACCTGCTGGGGGTGTTTCTGGGGGGCGCCTACCAAGAAATCCTGGGGGATCTGCACAACCTGTTT
GGAGACACCAACGCGGTGCACATCCGCACCCGTCCCGGCGGCTACCAAGTCACCCAAGTCATCAAGGGGGACACCATCGG
CGAAGTGCTGAGCTGGGTGCAGTACAACAGCGAAGACCTGGTGGAAACCCTCCACCACGCCACCGAAGCCGCGCTACAAA
GGGGGCAGATCACTCTAGAGCAGGCTAGGGCGCTGCAGCAGCACTTTGAAGACAACCTGCGGGCCTACACTTACCTGCAC
CGCTAG

Upstream 100 bases:

>100_bases
GCCTTGGAAAAATCTTGACATATCTTGGAATAGGGCAATATATTGTGGATTCTGTGCAGAAATCCTGCGCTGTTCACATC
TCGGTATCTGGGGGACTACT

Downstream 100 bases:

>100_bases
CTGCCCCTCTGCCATCCCGGCTTTAGCTCGTGGGGGTGGTGGGGGTGGCTGAGCCCTGCGCTGTACTCAGTGCCGGGAGT
AGGTCACGGAAGGGGTGGGC

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MPTLTRSPWTLRDSEKLYRISGWGDPYFRINAAGHVEVTPQGSQQQEGGIDLYHLVTDLVARGLQLPLLIRFPEIVADRM
RRICESFQQAIERFGYPNVYRGVYPVKVNQQRHLVEEVVKHGRAYHFGLEAGSKPELLIALALLDTPGALLICNGYKDRD
FMETALLAQRLGRTPIIVLERLQELELVLQAAEHLGIDPLLGVRAKLSAQGSGRWGTSAGDRGKFGLTATEMLQVVERLR
EVGKLHCLRLLHYHIGSQISMVSVHGRAVREASQIYIELVKLGAPMGYLDVGGGLGVDYDGSQSTSHFSQSYSLEDYAAT
VVQTVLTALQPHGIQPPVLVTESGRALMSHQSVLVFDIQDVNAASPYPMPTQLTSDAEVIQKLNQLYYEIRPETLVADYR
RCQELKEAALRQFTEGSLSLRERAEVERLFWNCSDKICTLAYEQHQAGQPVAVDLLDLDEMLASIYYGNFSLFQSLPDSW
AIDQVFPIMPIHRLDEEPRQWATLADLTCDSDGKINRFFGEDGQITSVLPLHDPNGQPYLLGVFLGGAYQEILGDLHNLF
GDTNAVHIRTRPGGYQVTQVIKGDTIGEVLSWVQYNSEDLVETLHHATEAALQRGQITLEQARALQQHFEDNLRAYTYLH
R

Sequences:

>Translated_641_residues
MPTLTRSPWTLRDSEKLYRISGWGDPYFRINAAGHVEVTPQGSQQQEGGIDLYHLVTDLVARGLQLPLLIRFPEIVADRM
RRICESFQQAIERFGYPNVYRGVYPVKVNQQRHLVEEVVKHGRAYHFGLEAGSKPELLIALALLDTPGALLICNGYKDRD
FMETALLAQRLGRTPIIVLERLQELELVLQAAEHLGIDPLLGVRAKLSAQGSGRWGTSAGDRGKFGLTATEMLQVVERLR
EVGKLHCLRLLHYHIGSQISMVSVHGRAVREASQIYIELVKLGAPMGYLDVGGGLGVDYDGSQSTSHFSQSYSLEDYAAT
VVQTVLTALQPHGIQPPVLVTESGRALMSHQSVLVFDIQDVNAASPYPMPTQLTSDAEVIQKLNQLYYEIRPETLVADYR
RCQELKEAALRQFTEGSLSLRERAEVERLFWNCSDKICTLAYEQHQAGQPVAVDLLDLDEMLASIYYGNFSLFQSLPDSW
AIDQVFPIMPIHRLDEEPRQWATLADLTCDSDGKINRFFGEDGQITSVLPLHDPNGQPYLLGVFLGGAYQEILGDLHNLF
GDTNAVHIRTRPGGYQVTQVIKGDTIGEVLSWVQYNSEDLVETLHHATEAALQRGQITLEQARALQQHFEDNLRAYTYLH
R
>Mature_640_residues
PTLTRSPWTLRDSEKLYRISGWGDPYFRINAAGHVEVTPQGSQQQEGGIDLYHLVTDLVARGLQLPLLIRFPEIVADRMR
RICESFQQAIERFGYPNVYRGVYPVKVNQQRHLVEEVVKHGRAYHFGLEAGSKPELLIALALLDTPGALLICNGYKDRDF
METALLAQRLGRTPIIVLERLQELELVLQAAEHLGIDPLLGVRAKLSAQGSGRWGTSAGDRGKFGLTATEMLQVVERLRE
VGKLHCLRLLHYHIGSQISMVSVHGRAVREASQIYIELVKLGAPMGYLDVGGGLGVDYDGSQSTSHFSQSYSLEDYAATV
VQTVLTALQPHGIQPPVLVTESGRALMSHQSVLVFDIQDVNAASPYPMPTQLTSDAEVIQKLNQLYYEIRPETLVADYRR
CQELKEAALRQFTEGSLSLRERAEVERLFWNCSDKICTLAYEQHQAGQPVAVDLLDLDEMLASIYYGNFSLFQSLPDSWA
IDQVFPIMPIHRLDEEPRQWATLADLTCDSDGKINRFFGEDGQITSVLPLHDPNGQPYLLGVFLGGAYQEILGDLHNLFG
DTNAVHIRTRPGGYQVTQVIKGDTIGEVLSWVQYNSEDLVETLHHATEAALQRGQITLEQARALQQHFEDNLRAYTYLHR

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=631, Percent_Identity=39.3026941362916, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71854; Mature: 71722

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLTRSPWTLRDSEKLYRISGWGDPYFRINAAGHVEVTPQGSQQQEGGIDLYHLVTDLV
CCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHH
ARGLQLPLLIRFPEIVADRMRRICESFQQAIERFGYPNVYRGVYPVKVNQQRHLVEEVVK
HCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCEEEEEECHHHHHHHHHHH
HGRAYHFGLEAGSKPELLIALALLDTPGALLICNGYKDRDFMETALLAQRLGRTPIIVLE
CCCEEEEECCCCCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHH
RLQELELVLQAAEHLGIDPLLGVRAKLSAQGSGRWGTSAGDRGKFGLTATEMLQVVERLR
HHHHHHHHHHHHHHCCCCCHHCCHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
EVGKLHCLRLLHYHIGSQISMVSVHGRAVREASQIYIELVKLGAPMGYLDVGGGLGVDYD
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCC
GSQSTSHFSQSYSLEDYAATVVQTVLTALQPHGIQPPVLVTESGRALMSHQSVLVFDIQD
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHCCCCEEEEEECC
VNAASPYPMPTQLTSDAEVIQKLNQLYYEIRPETLVADYRRCQELKEAALRQFTEGSLSL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RERAEVERLFWNCSDKICTLAYEQHQAGQPVAVDLLDLDEMLASIYYGNFSLFQSLPDSW
HHHHHHHHHHHCCCCHHEEEEEHHHCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHCCCCC
AIDQVFPIMPIHRLDEEPRQWATLADLTCDSDGKINRFFGEDGQITSVLPLHDPNGQPYL
CHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEE
LGVFLGGAYQEILGDLHNLFGDTNAVHIRTRPGGYQVTQVIKGDTIGEVLSWVQYNSEDL
EEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEHHHHCCCCHHHHHHHHHCCHHHH
VETLHHATEAALQRGQITLEQARALQQHFEDNLRAYTYLHR
HHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCHHHHHEECC
>Mature Secondary Structure 
PTLTRSPWTLRDSEKLYRISGWGDPYFRINAAGHVEVTPQGSQQQEGGIDLYHLVTDLV
CCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHH
ARGLQLPLLIRFPEIVADRMRRICESFQQAIERFGYPNVYRGVYPVKVNQQRHLVEEVVK
HCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCEEEEEECHHHHHHHHHHH
HGRAYHFGLEAGSKPELLIALALLDTPGALLICNGYKDRDFMETALLAQRLGRTPIIVLE
CCCEEEEECCCCCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHH
RLQELELVLQAAEHLGIDPLLGVRAKLSAQGSGRWGTSAGDRGKFGLTATEMLQVVERLR
HHHHHHHHHHHHHHCCCCCHHCCHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
EVGKLHCLRLLHYHIGSQISMVSVHGRAVREASQIYIELVKLGAPMGYLDVGGGLGVDYD
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCC
GSQSTSHFSQSYSLEDYAATVVQTVLTALQPHGIQPPVLVTESGRALMSHQSVLVFDIQD
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHCCCCEEEEEECC
VNAASPYPMPTQLTSDAEVIQKLNQLYYEIRPETLVADYRRCQELKEAALRQFTEGSLSL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RERAEVERLFWNCSDKICTLAYEQHQAGQPVAVDLLDLDEMLASIYYGNFSLFQSLPDSW
HHHHHHHHHHHCCCCHHEEEEEHHHCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHCCCCC
AIDQVFPIMPIHRLDEEPRQWATLADLTCDSDGKINRFFGEDGQITSVLPLHDPNGQPYL
CHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEE
LGVFLGGAYQEILGDLHNLFGDTNAVHIRTRPGGYQVTQVIKGDTIGEVLSWVQYNSEDL
EEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEHHHHCCCCHHHHHHHHHCCHHHH
VETLHHATEAALQRGQITLEQARALQQHFEDNLRAYTYLHR
HHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]