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The map label for this gene is fhuA

Identifier: 86361199

GI number: 86361199

Start: 528482

End: 530656

Strand: Reverse

Name: fhuA

Synonym: RHE_PF00469

Alternate gene names: 86361199

Gene position: 530656-528482 (Counterclockwise)

Preceding gene: 86361202

Following gene: 86361198

Centisome position: 82.59

GC content: 60.23

Gene sequence:

>2175_bases
ATGGCGCGTGTTTTTTTGAATGTTTCTAATAATGTATCGCGAATTTACAGAGAAAGTCTTTTTGCGACGACCGCGATCCT
CCTGATCGGCATTGCAGCATCGCCGGCTGCTGCCCAGAGCGCCTCCGCAGGTGACACCGCGACGACGCTGGAGCCAATCG
TCATTCAAGGTGCATCCTCTGATAGCAAGGCCGACCGGACGTCGGTCACCGCCAAGAACAGCGCCGGCGCGACCAAGATC
AGCACGCCGCTCGTCGAGACGCCACGTTCCGTTTCGGTCACCACCGAGAAGGAGATCGAGCAGCGCGGCGCCCAGACAGT
CATCGAGGCGGTGCGTTATACGGCCGGCGTGACGACCGGGCCGAACGGCTTCGATCCGCGTTTCGACCAGATCTACATTC
GCGGCTTCAACATCACCACAGTCGGAGACTTTCGTGACAGCCTGCGCCAGCCCTACATCAATTACGGCATGTTCCGCACC
GATCCCTATCAGCTGCAGCGCGTCGAGGTGATCAAGGGACCGGTTTCCGTTCTCTACGGCGCGGGATCGCCGGGCGGCCT
GATCAACAAGATATCGAAGCTTCCGACCGAGGAGCCGATCCGCGAAGTCGGCATCAGCTACGGCACTGAGGACCGGCTGC
AGGGGATGTTCGATTTCGGTGGGCCGATCGGCGAAGGCAAAGACGATTTTCTCTATCGCATCGTCGGCCTCGCCCGCCGC
GGTGATACCAATTTCGACATTGCCGACGACCGCTATTTCCTGGCGCCGTCCTTCACCTGGAAGCCCGACGAGGGCACGAT
GTTCACGGTGTACGGCCTGGCGCAGTCGGACGAGACCGACTCCAACGTCGGCGCGATCACGACCTTGGACGGGAAGATCC
ACGAGCTCAGGGAGAGCGATCCCGACTACGACGACCAGAAGGTCAGGCAGCAGCAGGTCGGCTATCAGTTCGAGCATGAA
TTCGACAACGGCCTGACCTTCCGGCAGAACCTGCGTTACTCGCATCTCAATCTGGAGGCTCGCTATCTCGGTGTTACCGG
CTGGACCGGGACCGTCGCGCATCGTGGCACAAATGCGATCCGCGACGAAATGAACGTGTTCCAGGTCGACAACCAGCTCG
AATCGAAGTTCGACACGGGCCCGTTGGCCCATACGATGCTGTTCGGGCTCGACTACACCAATCTCCAGTCGAGCTTTGGC
TACGGCGCCGGCGCTGCCGATCCGGCGTTCGACTTCGATATCGCCAATCCGACCTATGGTGTCTCGGGCGCCACGCCGGA
CTACAGCATCCTGGCTTCCGATGCCGACATGCGGCAGGTCGGCATTTACGCGCTGGACCAGATCGAGGTCGGGAACTGGC
GGTTCAACCTCGGCGGCCGGCAGACCTGGGTGAACCAGACGCGCGATGCGATTTTGCCCGCGGTCAGCTCGGAGGAGGTC
GATAAGAACGCCTTCTCCTGGCAAGCCGGTGCCCTCTACCTCTTCGACAACGGCATTGCTCCCTTCGTCTCCTACGCCAC
CTCGTTCGATCCGGTGACCAACCGTTCGACCTCAGGCAAGATCCTGGCGCCGACAGAGGGTGAACAGTACGAGGTAGGTG
TGAAATACCAGCCGCCGGGCTCCGACATCCTGCTGTCGGCCATTGCCTATCACATCGTCGAAAAGAACAAGCCGGTGCTG
GTCGACCCGCTGTTGTTTGCCTATGGATCGATCGGTGAGGTGACCGGAAAGGGTATCGAACTGGAAGCCCGCGCGGCGGT
AGCCGATGGCTGGGATCTCATTGCGGCCTACACCTACAACCATTCAGAAGTGACGGGAGGCGGCGAAAACGAGGGCAATA
CGCCAGCCCTCACACCTTCACATGTCGCCAGCCTCTGGGCCAACTACACGTTCCAGGAAACCAACCCCTTCCATGGCCTT
TCCGTCGGCGCGGGTGTCCGTTATGTCAGCGAGAATTGGACGGATACGGCGAATACGTCAAAGAACCCCTCGAGCTTCTA
CATCGACGCGTCCGCCGCTTATGACTTCGGCGCGGTCGACAAGAAATACGAAGGCCTGACTGCAGCCTTCAATATCCGCA
ACATCGCCGATGAACGCGATACCGTTTGCAACGAGGGCTTCTGCTACCTCGGCCAGGGTCGCAACATGACCGGCACCCTG
AAGTATCGGTGGTAG

Upstream 100 bases:

>100_bases
AGATCATCGAATAAAAGCTGACAAAAATAATCACCTTATGTTGACAAGCTCTATTTCGCTCCATAGGTTCCGCCCGCATC
CGTGACGTAGGGACCAAGCA

Downstream 100 bases:

>100_bases
CACCATGGCGGCGGAGATGAACGGGGCGGCCTCACGCCCTTCGATCGCCGATCATCCTGTCGCCCACCAGGCGGTCGACC
TCGACGGCCTGGTGGGCGAT

Product: ferrichrome-iron transporter, receptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MARVFLNVSNNVSRIYRESLFATTAILLIGIAASPAAAQSASAGDTATTLEPIVIQGASSDSKADRTSVTAKNSAGATKI
STPLVETPRSVSVTTEKEIEQRGAQTVIEAVRYTAGVTTGPNGFDPRFDQIYIRGFNITTVGDFRDSLRQPYINYGMFRT
DPYQLQRVEVIKGPVSVLYGAGSPGGLINKISKLPTEEPIREVGISYGTEDRLQGMFDFGGPIGEGKDDFLYRIVGLARR
GDTNFDIADDRYFLAPSFTWKPDEGTMFTVYGLAQSDETDSNVGAITTLDGKIHELRESDPDYDDQKVRQQQVGYQFEHE
FDNGLTFRQNLRYSHLNLEARYLGVTGWTGTVAHRGTNAIRDEMNVFQVDNQLESKFDTGPLAHTMLFGLDYTNLQSSFG
YGAGAADPAFDFDIANPTYGVSGATPDYSILASDADMRQVGIYALDQIEVGNWRFNLGGRQTWVNQTRDAILPAVSSEEV
DKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILAPTEGEQYEVGVKYQPPGSDILLSAIAYHIVEKNKPVL
VDPLLFAYGSIGEVTGKGIELEARAAVADGWDLIAAYTYNHSEVTGGGENEGNTPALTPSHVASLWANYTFQETNPFHGL
SVGAGVRYVSENWTDTANTSKNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTGTL
KYRW

Sequences:

>Translated_724_residues
MARVFLNVSNNVSRIYRESLFATTAILLIGIAASPAAAQSASAGDTATTLEPIVIQGASSDSKADRTSVTAKNSAGATKI
STPLVETPRSVSVTTEKEIEQRGAQTVIEAVRYTAGVTTGPNGFDPRFDQIYIRGFNITTVGDFRDSLRQPYINYGMFRT
DPYQLQRVEVIKGPVSVLYGAGSPGGLINKISKLPTEEPIREVGISYGTEDRLQGMFDFGGPIGEGKDDFLYRIVGLARR
GDTNFDIADDRYFLAPSFTWKPDEGTMFTVYGLAQSDETDSNVGAITTLDGKIHELRESDPDYDDQKVRQQQVGYQFEHE
FDNGLTFRQNLRYSHLNLEARYLGVTGWTGTVAHRGTNAIRDEMNVFQVDNQLESKFDTGPLAHTMLFGLDYTNLQSSFG
YGAGAADPAFDFDIANPTYGVSGATPDYSILASDADMRQVGIYALDQIEVGNWRFNLGGRQTWVNQTRDAILPAVSSEEV
DKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILAPTEGEQYEVGVKYQPPGSDILLSAIAYHIVEKNKPVL
VDPLLFAYGSIGEVTGKGIELEARAAVADGWDLIAAYTYNHSEVTGGGENEGNTPALTPSHVASLWANYTFQETNPFHGL
SVGAGVRYVSENWTDTANTSKNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTGTL
KYRW
>Mature_723_residues
ARVFLNVSNNVSRIYRESLFATTAILLIGIAASPAAAQSASAGDTATTLEPIVIQGASSDSKADRTSVTAKNSAGATKIS
TPLVETPRSVSVTTEKEIEQRGAQTVIEAVRYTAGVTTGPNGFDPRFDQIYIRGFNITTVGDFRDSLRQPYINYGMFRTD
PYQLQRVEVIKGPVSVLYGAGSPGGLINKISKLPTEEPIREVGISYGTEDRLQGMFDFGGPIGEGKDDFLYRIVGLARRG
DTNFDIADDRYFLAPSFTWKPDEGTMFTVYGLAQSDETDSNVGAITTLDGKIHELRESDPDYDDQKVRQQQVGYQFEHEF
DNGLTFRQNLRYSHLNLEARYLGVTGWTGTVAHRGTNAIRDEMNVFQVDNQLESKFDTGPLAHTMLFGLDYTNLQSSFGY
GAGAADPAFDFDIANPTYGVSGATPDYSILASDADMRQVGIYALDQIEVGNWRFNLGGRQTWVNQTRDAILPAVSSEEVD
KNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILAPTEGEQYEVGVKYQPPGSDILLSAIAYHIVEKNKPVLV
DPLLFAYGSIGEVTGKGIELEARAAVADGWDLIAAYTYNHSEVTGGGENEGNTPALTPSHVASLWANYTFQETNPFHGLS
VGAGVRYVSENWTDTANTSKNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTGTLK
YRW

Specific function: Involved in the initial step of iron uptake by binding chrysobactin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=704, Percent_Identity=32.9545454545455, Blast_Score=347, Evalue=2e-96,
Organism=Escherichia coli, GI1787344, Length=780, Percent_Identity=23.974358974359, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1787024, Length=705, Percent_Identity=23.2624113475177, Blast_Score=116, Evalue=7e-27,
Organism=Escherichia coli, GI1790743, Length=683, Percent_Identity=22.4011713030747, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79085; Mature: 78954

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVFLNVSNNVSRIYRESLFATTAILLIGIAASPAAAQSASAGDTATTLEPIVIQGASS
CEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCHHCCCCCCCCCCCCCEEEEECCCC
DSKADRTSVTAKNSAGATKISTPLVETPRSVSVTTEKEIEQRGAQTVIEAVRYTAGVTTG
CCCCCCCEEEECCCCCCCEECCCHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCC
PNGFDPRFDQIYIRGFNITTVGDFRDSLRQPYINYGMFRTDPYQLQRVEVIKGPVSVLYG
CCCCCCCCCEEEEEEEEEEEEHHHHHHHCCCHHHCCCEECCHHHEEEEEEECCCEEEEEE
AGSPGGLINKISKLPTEEPIREVGISYGTEDRLQGMFDFGGPIGEGKDDFLYRIVGLARR
CCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
GDTNFDIADDRYFLAPSFTWKPDEGTMFTVYGLAQSDETDSNVGAITTLDGKIHELRESD
CCCCCEECCCCEEECCCCEECCCCCCEEEEEEECCCCCCCCCCCEEEEECCHHHHHHCCC
PDYDDQKVRQQQVGYQFEHEFDNGLTFRQNLRYSHLNLEARYLGVTGWTGTVAHRGTNAI
CCCCHHHHHHHHCCCEEEECCCCCCEEHHCCCEEEEEEEEEEEEEECCCCCHHHCCCHHH
RDEMNVFQVDNQLESKFDTGPLAHTMLFGLDYTNLQSSFGYGAGAADPAFDFDIANPTYG
HHCCHHEEECHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEECCCCCCC
VSGATPDYSILASDADMRQVGIYALDQIEVGNWRFNLGGRQTWVNQTRDAILPAVSSEEV
CCCCCCCCEEEECCCCCHHCCEEEEEEEEECCEEEECCCCHHHHHHHHHHHCCCCCCCCC
DKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILAPTEGEQYEVGVKYQPPG
CCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCC
SDILLSAIAYHIVEKNKPVLVDPLLFAYGSIGEVTGKGIELEARAAVADGWDLIAAYTYN
CHHHHHHHHHHHHCCCCCEEECHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEC
HSEVTGGGENEGNTPALTPSHVASLWANYTFQETNPFHGLSVGAGVRYVSENWTDTANTS
CCEECCCCCCCCCCCCCCHHHHHHHHHCCEECCCCCCCCEECCCCEEEECCCCCCCCCCC
KNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTGTL
CCCCEEEEECCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHCCCCEEEECCCCCEEEE
KYRW
EECC
>Mature Secondary Structure 
ARVFLNVSNNVSRIYRESLFATTAILLIGIAASPAAAQSASAGDTATTLEPIVIQGASS
EEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCHHCCCCCCCCCCCCCEEEEECCCC
DSKADRTSVTAKNSAGATKISTPLVETPRSVSVTTEKEIEQRGAQTVIEAVRYTAGVTTG
CCCCCCCEEEECCCCCCCEECCCHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCC
PNGFDPRFDQIYIRGFNITTVGDFRDSLRQPYINYGMFRTDPYQLQRVEVIKGPVSVLYG
CCCCCCCCCEEEEEEEEEEEEHHHHHHHCCCHHHCCCEECCHHHEEEEEEECCCEEEEEE
AGSPGGLINKISKLPTEEPIREVGISYGTEDRLQGMFDFGGPIGEGKDDFLYRIVGLARR
CCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
GDTNFDIADDRYFLAPSFTWKPDEGTMFTVYGLAQSDETDSNVGAITTLDGKIHELRESD
CCCCCEECCCCEEECCCCEECCCCCCEEEEEEECCCCCCCCCCCEEEEECCHHHHHHCCC
PDYDDQKVRQQQVGYQFEHEFDNGLTFRQNLRYSHLNLEARYLGVTGWTGTVAHRGTNAI
CCCCHHHHHHHHCCCEEEECCCCCCEEHHCCCEEEEEEEEEEEEEECCCCCHHHCCCHHH
RDEMNVFQVDNQLESKFDTGPLAHTMLFGLDYTNLQSSFGYGAGAADPAFDFDIANPTYG
HHCCHHEEECHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEECCCCCCC
VSGATPDYSILASDADMRQVGIYALDQIEVGNWRFNLGGRQTWVNQTRDAILPAVSSEEV
CCCCCCCCEEEECCCCCHHCCEEEEEEEEECCEEEECCCCHHHHHHHHHHHCCCCCCCCC
DKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILAPTEGEQYEVGVKYQPPG
CCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCC
SDILLSAIAYHIVEKNKPVLVDPLLFAYGSIGEVTGKGIELEARAAVADGWDLIAAYTYN
CHHHHHHHHHHHHCCCCCEEECHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEC
HSEVTGGGENEGNTPALTPSHVASLWANYTFQETNPFHGLSVGAGVRYVSENWTDTANTS
CCEECCCCCCCCCCCCCCHHHHHHHHHCCEECCCCCCCCEECCCCEEEECCCCCCCCCCC
KNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTGTL
CCCCEEEEECCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHCCCCEEEECCCCCEEEE
KYRW
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8576065 [H]