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The map label for this gene is yjmC [H]

Identifier: 86361158

GI number: 86361158

Start: 481156

End: 481863

Strand: Direct

Name: yjmC [H]

Synonym: RHE_PF00428

Alternate gene names: 86361158

Gene position: 481156-481863 (Clockwise)

Preceding gene: 86361156

Following gene: 86361159

Centisome position: 74.89

GC content: 65.68

Gene sequence:

>708_bases
ATGTCGGATGAGGTTCTATTCGATCTGGCGGAAGCCGAAAGCTTGGCGATGCGCGCCTGCCGGGCGGCAGGCGCCAGCGA
AGCCACCGCCCGTTCCCTCGTGGACGCCACCTTGTCCGCCGCGCTTTATGGACCCCCGGCCGTCGGGTTTCCGCATTTCG
TCGATTACCTCGACAGCTTCCGCGAGGGCCGCATCAATCGCGACCCCGCTCCCACCTGTGAGCGTCCTTACCCCGCCTTC
TTCGCCGCGGACGCCGATCGGGGGATAGCGCAGCTCGGTTTCGAACTTGCCTTCAAGGATCTGGTCGAAGCGGTGCGTAC
GCTCGGGGTCGCGGTCTTCACGCAAACGAACAGCTATACCACAGGAGAACTCGGCTATTACGTTCGCCGTCTCGCCGGCG
AAGGGATCGTCGGCATCGCCGCAACCAACGCCAATGCCATGGTGGTCGCCAAAGCGGGCGGCCCCGCCGTCTACAGTACG
AATCCGATGGCCTTCGGCTTTCCGCTTGGCGACGGATCGCCCCCGCTCCTCATCGACCAGGCGTCGAGCGCGACCGCCTA
TGTCAACGTCGCCGCAGCCGCGGCGGAGGGACGCAGCATCCCGGAGGGATGGGCCGTCGATGAAGCGGGACAGGAAACTC
AGGATGCCGCAAGAGCGGCGGAGCTCTCCTTCACTTCGGCGGGCGCAAGGGCGCTAATGTGGCGCTGA

Upstream 100 bases:

>100_bases
GTACATTTTCCCTGTCAGCGCGTCGCCACCTTTGGTAAAGAAACCTCTGAACGGCCCGGACCGGTCGGTCTGCAAGGAGA
GAAACAGGAGCAGATTCAAG

Downstream 100 bases:

>100_bases
TGGTGGAAATGCTGTCGGCCGGCCTGTCCCGTCGCCCCTGGTGATTGGATACACCGTCTTTCAGATCGGGGAGCGCCAGC
CCCGCTGTCGGGTCGACAAT

Product: putative malate dehydrogenase protein

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSDEVLFDLAEAESLAMRACRAAGASEATARSLVDATLSAALYGPPAVGFPHFVDYLDSFREGRINRDPAPTCERPYPAF
FAADADRGIAQLGFELAFKDLVEAVRTLGVAVFTQTNSYTTGELGYYVRRLAGEGIVGIAATNANAMVVAKAGGPAVYST
NPMAFGFPLGDGSPPLLIDQASSATAYVNVAAAAAEGRSIPEGWAVDEAGQETQDAARAAELSFTSAGARALMWR

Sequences:

>Translated_235_residues
MSDEVLFDLAEAESLAMRACRAAGASEATARSLVDATLSAALYGPPAVGFPHFVDYLDSFREGRINRDPAPTCERPYPAF
FAADADRGIAQLGFELAFKDLVEAVRTLGVAVFTQTNSYTTGELGYYVRRLAGEGIVGIAATNANAMVVAKAGGPAVYST
NPMAFGFPLGDGSPPLLIDQASSATAYVNVAAAAAEGRSIPEGWAVDEAGQETQDAARAAELSFTSAGARALMWR
>Mature_234_residues
SDEVLFDLAEAESLAMRACRAAGASEATARSLVDATLSAALYGPPAVGFPHFVDYLDSFREGRINRDPAPTCERPYPAFF
AADADRGIAQLGFELAFKDLVEAVRTLGVAVFTQTNSYTTGELGYYVRRLAGEGIVGIAATNANAMVVAKAGGPAVYSTN
PMAFGFPLGDGSPPLLIDQASSATAYVNVAAAAAEGRSIPEGWAVDEAGQETQDAARAAELSFTSAGARALMWR

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=215, Percent_Identity=28.8372093023256, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787020, Length=217, Percent_Identity=27.1889400921659, Blast_Score=75, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24667904, Length=221, Percent_Identity=23.9819004524887, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24667908, Length=221, Percent_Identity=23.9819004524887, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45553211, Length=221, Percent_Identity=23.9819004524887, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24667912, Length=221, Percent_Identity=23.9819004524887, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 24527; Mature: 24395

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDEVLFDLAEAESLAMRACRAAGASEATARSLVDATLSAALYGPPAVGFPHFVDYLDSF
CCCHHEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
REGRINRDPAPTCERPYPAFFAADADRGIAQLGFELAFKDLVEAVRTLGVAVFTQTNSYT
HCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
TGELGYYVRRLAGEGIVGIAATNANAMVVAKAGGPAVYSTNPMAFGFPLGDGSPPLLIDQ
CHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCEEEECCCEEEEEECCCCCCCEEEEC
ASSATAYVNVAAAAAEGRSIPEGWAVDEAGQETQDAARAAELSFTSAGARALMWR
CCCCEEEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure 
SDEVLFDLAEAESLAMRACRAAGASEATARSLVDATLSAALYGPPAVGFPHFVDYLDSF
CCHHEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
REGRINRDPAPTCERPYPAFFAADADRGIAQLGFELAFKDLVEAVRTLGVAVFTQTNSYT
HCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
TGELGYYVRRLAGEGIVGIAATNANAMVVAKAGGPAVYSTNPMAFGFPLGDGSPPLLIDQ
CHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCEEEECCCEEEEEECCCCCCCEEEEC
ASSATAYVNVAAAAAEGRSIPEGWAVDEAGQETQDAARAAELSFTSAGARALMWR
CCCCEEEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]