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The map label for this gene is ydeP [H]

Identifier: 86361146

GI number: 86361146

Start: 468324

End: 470618

Strand: Reverse

Name: ydeP [H]

Synonym: RHE_PF00416

Alternate gene names: 86361146

Gene position: 470618-468324 (Counterclockwise)

Preceding gene: 86361147

Following gene: 86361145

Centisome position: 73.25

GC content: 62.18

Gene sequence:

>2295_bases
ATGGACACAAAATTTATCGGCAAGAAATCGGCGGCAGCCGGCGGCTGGGGCGCTCTGAAAAGCTGCGGCAAACAATTGCT
GCAAAGCGGCATGCCGGTCTCGGGGGCGCGGACGATGCTGAAGGCGAACCAGCCGGACGGCTTCGATTGCCCGGGCTGCG
CCTGGGGCGATCCGGAACACGGCTCGTCGTTCGAATTTTGTGAAAACGGCGTGAAGGCCGTCGCCTGGGAGGCGACAGAA
AAGCGGGCGACACCCGCCTTCTTCGCGGCGAATACCGTCTCCGAGCTTCGCCGGTTGTCGGATTACGAACTGGAACTCAA
TGGCCGCCTCACGCATCCGATGCGTTACGATGCTGCGAGCGACCGTTATCTGCCGGTGGCGTGGGAGGATGCTTTTGCCG
AGATCGGCAGCATTCTGAAGGGCCTCGATAATCCCAATCGGGCGGAGTTCTATACGTCCGGCCGCGCCAGCAACGAGGCT
GCCTTCCTCTATCAGCTGTTCGTGCGCATCTACGGCACCAACAATTTTCCCGATTGTTCCAACATGTGTCACGAGGCAAG
TGGAATCGCGCTGAACCAGGCGATCGGCGTCGGCAAGGGCACCGTGCTTCTGGAGGACTTCGAGGAGGCCGATGCGATCT
TCGTGATCGGCCAGAACCCCGGAACCAATCATCCCCGAATGCTCGGCGACCTGCGCCGGGCGGCGATGCGCGGCGCGCGG
ATCGTCGTCTTCAATCCGATCCGCGAGCGCGGGTTGGAGCGTTTCTCCGATCCGCAGGACAAGATCGAGATGCTGCGCGG
CGGCGCGACCGATATCGCCGGCCTCTATCTGCAACCGCAGCTCGGCGGCGACATGGCCGCTGTGCGTGGAATGGCAAAGG
CGGTGCTGGCCGCGGAAGACGCTGCAGTTGCCGCCGGTCTGCCGCCGGTTCTCGATCATGCGTTCCTGGCCGACCATTGC
GCCGGGTTTGCGCAATACCGGGCAGCGGTCGAGGCGACGGCCTGGGCTGATATCGAAGACCAATCGGGGCTAAGCCGACA
GGACATCGAAGAGGCCGCCGATGTCTATATCAGGGCCGAACGGGTCATCTGCACCTGGGCAATGGGAGTGACCCAGCACC
GGCATTCGGTGGCGACGATCCGGGAGATCGCCAACTTCATGTTCCTGCGCGGCAATATTGGCAAGCCTGGCGCCGGTCTT
TGCCCGGTTCGCGGCCATTCCAACGTCCAGGGAGACCGGACCGTCGGCATCAATGAAAAGCCTGCGGACGGTTTCCTCGA
TGCGCTGGAGAAGCATTTCGGCTTCTCCGTGCCGCGTGACCATGGCCACCATGTTCTTGCCGCGATCGGGGCGATGCTTG
ACGGGTCGGCCGAGGCCTTCATCGGGCTTGGCGGCAATTTTGCCCGTGCGACGCCCGACAGCGCACTGGTCGAAAAAGCG
CTTCGGCAGCTGAAGCTGACGGTGCACATCGCCACCAAACCCAATCATTCACATCTGATGCCCGGCGAGGCGTCCTTCAT
TCTGCCCTGCCTCGGGCGTACCGAGATGGATCTGAACGCTGCCGGTAATTCTCAACTCATCAGTGTCGAAGACTCGATGA
GCATGGTGCATGGATCAGCCGGCATCAATCGCCCCGCCTCGCCGCATCTCCTCTCGGAAGTCGCCATCATTGCCGGCATT
GCGCAGGCAACGGTCGGCTCCTCCGTGGCCGACTGGGCAGAGCTGGCCGACGACTACGACCGCATCCGCAATCATATCGA
GGCGACTATTCCCGGCTTTGAAAACTATAATGCCCGCCTTCGCAAGCCGCGCGGTTTCCATCTGCGCAATCCGGCCGCCC
ATCGGGAGTGGCAGACGCCGGCAGGCAGGGCATCATTCTCTTGCCCGGCGCTTCCAGAGCAGACCGTGCACCAGCGTGCG
CGAAGAGGCGAGGGGCGTTTCGCTCTGCAGACGTTCCGGTCGCACGACCAATACAATACGACGGTCTATGGTCTCGATGA
CCGATATCGCGGTGTCTACGGAGAGCGGCAGGTCATCTTCATTCATCCGGCGGATCTGAAGGCGATGAATGCCGAGGCTG
GTGACCGTGTCGACGTGATCGGCGATCACGATGACGGCATCGAGCGTATCGCGCGGGATTTCCGCTTCGTGCCCTATGAT
ATTCCGCAGGGCAGCATTGCCGGCTATTACCCGGAACTGAACGTGCTCGTGCCGCTTGGCAGTGCCGGCGAGGAAAGCGA
TACGCCGACCTCGAAATCGATCATGGTTTCGTTGCGCAAGCGAGACGCCGCGTGA

Upstream 100 bases:

>100_bases
CTTAAGGAAACCGGTTAGGGTCCGCGCTCGATAGGTTTCTTCTATCGAGCCATCGTTCGTACACCCTTGATGTTTAGCGC
CCTTCAACAATACAGGGCGC

Downstream 100 bases:

>100_bases
GTAGCGAAGCTATCGGCGCAGACCGATTTCTTGCCCTTGTCGCTGCGGCGCAGGATAGGGACATCGGACTGACCTCCATA
CAGGCTGGTCTGCTCGTCGC

Product: formate dehydrogenase alpha chain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MDTKFIGKKSAAAGGWGALKSCGKQLLQSGMPVSGARTMLKANQPDGFDCPGCAWGDPEHGSSFEFCENGVKAVAWEATE
KRATPAFFAANTVSELRRLSDYELELNGRLTHPMRYDAASDRYLPVAWEDAFAEIGSILKGLDNPNRAEFYTSGRASNEA
AFLYQLFVRIYGTNNFPDCSNMCHEASGIALNQAIGVGKGTVLLEDFEEADAIFVIGQNPGTNHPRMLGDLRRAAMRGAR
IVVFNPIRERGLERFSDPQDKIEMLRGGATDIAGLYLQPQLGGDMAAVRGMAKAVLAAEDAAVAAGLPPVLDHAFLADHC
AGFAQYRAAVEATAWADIEDQSGLSRQDIEEAADVYIRAERVICTWAMGVTQHRHSVATIREIANFMFLRGNIGKPGAGL
CPVRGHSNVQGDRTVGINEKPADGFLDALEKHFGFSVPRDHGHHVLAAIGAMLDGSAEAFIGLGGNFARATPDSALVEKA
LRQLKLTVHIATKPNHSHLMPGEASFILPCLGRTEMDLNAAGNSQLISVEDSMSMVHGSAGINRPASPHLLSEVAIIAGI
AQATVGSSVADWAELADDYDRIRNHIEATIPGFENYNARLRKPRGFHLRNPAAHREWQTPAGRASFSCPALPEQTVHQRA
RRGEGRFALQTFRSHDQYNTTVYGLDDRYRGVYGERQVIFIHPADLKAMNAEAGDRVDVIGDHDDGIERIARDFRFVPYD
IPQGSIAGYYPELNVLVPLGSAGEESDTPTSKSIMVSLRKRDAA

Sequences:

>Translated_764_residues
MDTKFIGKKSAAAGGWGALKSCGKQLLQSGMPVSGARTMLKANQPDGFDCPGCAWGDPEHGSSFEFCENGVKAVAWEATE
KRATPAFFAANTVSELRRLSDYELELNGRLTHPMRYDAASDRYLPVAWEDAFAEIGSILKGLDNPNRAEFYTSGRASNEA
AFLYQLFVRIYGTNNFPDCSNMCHEASGIALNQAIGVGKGTVLLEDFEEADAIFVIGQNPGTNHPRMLGDLRRAAMRGAR
IVVFNPIRERGLERFSDPQDKIEMLRGGATDIAGLYLQPQLGGDMAAVRGMAKAVLAAEDAAVAAGLPPVLDHAFLADHC
AGFAQYRAAVEATAWADIEDQSGLSRQDIEEAADVYIRAERVICTWAMGVTQHRHSVATIREIANFMFLRGNIGKPGAGL
CPVRGHSNVQGDRTVGINEKPADGFLDALEKHFGFSVPRDHGHHVLAAIGAMLDGSAEAFIGLGGNFARATPDSALVEKA
LRQLKLTVHIATKPNHSHLMPGEASFILPCLGRTEMDLNAAGNSQLISVEDSMSMVHGSAGINRPASPHLLSEVAIIAGI
AQATVGSSVADWAELADDYDRIRNHIEATIPGFENYNARLRKPRGFHLRNPAAHREWQTPAGRASFSCPALPEQTVHQRA
RRGEGRFALQTFRSHDQYNTTVYGLDDRYRGVYGERQVIFIHPADLKAMNAEAGDRVDVIGDHDDGIERIARDFRFVPYD
IPQGSIAGYYPELNVLVPLGSAGEESDTPTSKSIMVSLRKRDAA
>Mature_764_residues
MDTKFIGKKSAAAGGWGALKSCGKQLLQSGMPVSGARTMLKANQPDGFDCPGCAWGDPEHGSSFEFCENGVKAVAWEATE
KRATPAFFAANTVSELRRLSDYELELNGRLTHPMRYDAASDRYLPVAWEDAFAEIGSILKGLDNPNRAEFYTSGRASNEA
AFLYQLFVRIYGTNNFPDCSNMCHEASGIALNQAIGVGKGTVLLEDFEEADAIFVIGQNPGTNHPRMLGDLRRAAMRGAR
IVVFNPIRERGLERFSDPQDKIEMLRGGATDIAGLYLQPQLGGDMAAVRGMAKAVLAAEDAAVAAGLPPVLDHAFLADHC
AGFAQYRAAVEATAWADIEDQSGLSRQDIEEAADVYIRAERVICTWAMGVTQHRHSVATIREIANFMFLRGNIGKPGAGL
CPVRGHSNVQGDRTVGINEKPADGFLDALEKHFGFSVPRDHGHHVLAAIGAMLDGSAEAFIGLGGNFARATPDSALVEKA
LRQLKLTVHIATKPNHSHLMPGEASFILPCLGRTEMDLNAAGNSQLISVEDSMSMVHGSAGINRPASPHLLSEVAIIAGI
AQATVGSSVADWAELADDYDRIRNHIEATIPGFENYNARLRKPRGFHLRNPAAHREWQTPAGRASFSCPALPEQTVHQRA
RRGEGRFALQTFRSHDQYNTTVYGLDDRYRGVYGERQVIFIHPADLKAMNAEAGDRVDVIGDHDDGIERIARDFRFVPYD
IPQGSIAGYYPELNVLVPLGSAGEESDTPTSKSIMVSLRKRDAA

Specific function: Probably involved in acid resistance [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787778, Length=758, Percent_Identity=49.868073878628, Blast_Score=763, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=453, Percent_Identity=27.3730684326711, Blast_Score=155, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: NA

Molecular weight: Translated: 82878; Mature: 82878

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKFIGKKSAAAGGWGALKSCGKQLLQSGMPVSGARTMLKANQPDGFDCPGCAWGDPEH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GSSFEFCENGVKAVAWEATEKRATPAFFAANTVSELRRLSDYELELNGRLTHPMRYDAAS
CCCHHHHHCCCEEEEEECHHCCCCCHHHHHHHHHHHHHCCCCEEEECCEECCCEECCCCC
DRYLPVAWEDAFAEIGSILKGLDNPNRAEFYTSGRASNEAAFLYQLFVRIYGTNNFPDCS
CCEEEEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHH
NMCHEASGIALNQAIGVGKGTVLLEDFEEADAIFVIGQNPGTNHPRMLGDLRRAAMRGAR
HHHHHHCCCEEHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCE
IVVFNPIRERGLERFSDPQDKIEMLRGGATDIAGLYLQPQLGGDMAAVRGMAKAVLAAED
EEEECCHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
AAVAAGLPPVLDHAFLADHCAGFAQYRAAVEATAWADIEDQSGLSRQDIEEAADVYIRAE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEEEEC
RVICTWAMGVTQHRHSVATIREIANFMFLRGNIGKPGAGLCPVRGHSNVQGDRTVGINEK
CEEEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCC
PADGFLDALEKHFGFSVPRDHGHHVLAAIGAMLDGSAEAFIGLGGNFARATPDSALVEKA
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHH
LRQLKLTVHIATKPNHSHLMPGEASFILPCLGRTEMDLNAAGNSQLISVEDSMSMVHGSA
HHHEEEEEEEEECCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCEEEEHHHHHHHHCCC
GINRPASPHLLSEVAIIAGIAQATVGSSVADWAELADDYDRIRNHIEATIPGFENYNARL
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEE
RKPRGFHLRNPAAHREWQTPAGRASFSCPALPEQTVHQRARRGEGRFALQTFRSHDQYNT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCC
TVYGLDDRYRGVYGERQVIFIHPADLKAMNAEAGDRVDVIGDHDDGIERIARDFRFVPYD
EEEECCHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEE
IPQGSIAGYYPELNVLVPLGSAGEESDTPTSKSIMVSLRKRDAA
CCCCCCCEECCCEEEEEECCCCCCCCCCCCCHHHHEEEHHHCCC
>Mature Secondary Structure
MDTKFIGKKSAAAGGWGALKSCGKQLLQSGMPVSGARTMLKANQPDGFDCPGCAWGDPEH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GSSFEFCENGVKAVAWEATEKRATPAFFAANTVSELRRLSDYELELNGRLTHPMRYDAAS
CCCHHHHHCCCEEEEEECHHCCCCCHHHHHHHHHHHHHCCCCEEEECCEECCCEECCCCC
DRYLPVAWEDAFAEIGSILKGLDNPNRAEFYTSGRASNEAAFLYQLFVRIYGTNNFPDCS
CCEEEEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHH
NMCHEASGIALNQAIGVGKGTVLLEDFEEADAIFVIGQNPGTNHPRMLGDLRRAAMRGAR
HHHHHHCCCEEHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCE
IVVFNPIRERGLERFSDPQDKIEMLRGGATDIAGLYLQPQLGGDMAAVRGMAKAVLAAED
EEEECCHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
AAVAAGLPPVLDHAFLADHCAGFAQYRAAVEATAWADIEDQSGLSRQDIEEAADVYIRAE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEEEEC
RVICTWAMGVTQHRHSVATIREIANFMFLRGNIGKPGAGLCPVRGHSNVQGDRTVGINEK
CEEEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCC
PADGFLDALEKHFGFSVPRDHGHHVLAAIGAMLDGSAEAFIGLGGNFARATPDSALVEKA
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHH
LRQLKLTVHIATKPNHSHLMPGEASFILPCLGRTEMDLNAAGNSQLISVEDSMSMVHGSA
HHHEEEEEEEEECCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCEEEEHHHHHHHHCCC
GINRPASPHLLSEVAIIAGIAQATVGSSVADWAELADDYDRIRNHIEATIPGFENYNARL
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEE
RKPRGFHLRNPAAHREWQTPAGRASFSCPALPEQTVHQRARRGEGRFALQTFRSHDQYNT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCC
TVYGLDDRYRGVYGERQVIFIHPADLKAMNAEAGDRVDVIGDHDDGIERIARDFRFVPYD
EEEECCHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEE
IPQGSIAGYYPELNVLVPLGSAGEESDTPTSKSIMVSLRKRDAA
CCCCCCCEECCCEEEEEECCCCCCCCCCCCCHHHHEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]