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The map label for this gene is 86361091

Identifier: 86361091

GI number: 86361091

Start: 406557

End: 407882

Strand: Direct

Name: 86361091

Synonym: RHE_PF00361

Alternate gene names: NA

Gene position: 406557-407882 (Clockwise)

Preceding gene: 86361089

Following gene: 86361097

Centisome position: 63.28

GC content: 65.69

Gene sequence:

>1326_bases
ATGCCCGCACCATTGACGCGCGTCGACACTACACCGCAGCTACCCGCTGCGGCGGATGCGGTCGTGATCGGCGGCGGCAT
CGTCGGCGTTTTCGCGGCCTATTATCTGTCGCGCCGCGGATTGAAAGTCGCCCTCGTCGAAAAGGGCCTCATCGGGGCCG
AACAGTCGAGCCGCAATTGGGGCTGGTGCCGGCAGCAGAACCGCGATGCCCGTGAATTGCCGATGTCGACGAAGAGCCTC
GATCTTTGGGAGCGCTTCGCCACTGAGACCGGCGAGGACACCGGCTTTCGCCGCTGTGGCCTCCTCTATCTCAGCAATAG
CGCGGAAGAACTCTCCGGCTGGGCTCGCTGGCGCGATTTCGCCCGATCGGTCGGCGTCACGACGCATATGCTGAGCAGCG
CGGAAGCAACCGAACGCGGGGGGGCCACCGGGACCGCGTGGAAAGGCGGGGTCTTTTCGCCGACCGACGGCACCGCCGAT
CCTGCAAGGGCGGCGCCTGCCGTCGCGCGTGCGATCCTGAAACTCGGCGGGACGGTGCATCAGTCCTGTGCGGCCCGCGG
CATCGACATCGAAGGCGGCAGAGTTTCAGGCGTCGTCACGGAGCATGGCATGATTCGAACGAAGGTCGCGATCCTGGCCG
GCGGCGCATGGGCATCAGCCTTCTGCCGCCAGCTCGGCATTCGATTTCCGCAAGCCTCGATCCGCTCGTCGATCCTCTCT
GTGTCGCCAGGCGCGAGCGGGCTGCCGGATGCGCTACATACATCTAGGGTTTCCGTGACACGTCGCGCCGACGGTGGTTA
CACGCTGGCCATCAGCGGCCGCGGCCGCGTCGATCCCACCGCGCAGCAGTTTCGTTTCGCACCGCAGTTCCTGCCGATGT
TTGCCCGGCGCTGGCGAAGTCTGGCACCTGGCGGATTGGAGGGAATTCGCTCGGGCCACGAATCTTTGGCACGGTGGCGG
CTCGACAGGCCGACGCCGATGGAGCGCATGCGCATTCTCGACCCGGCCGTCGATGAGGCGACCATTGCCCTCACACATGC
GCGGGCGATCAAGCTGCTGCCCGCCTTGAAAAAAGCCGAAATCAACGCGGCCTGGGCGGGCTACATCGACAGCACGCCAG
ACGGTGTGCCGGGGATCGGCGAGATTGCCTCCCTCCCGGGATTCATCCTGGCTGCGGGATTCAGCGGCCACGGTTTCGGT
ATCGGACCCGGCGCCGGTCATCTGATTGCCGATATCGTCACGGGCGATGAGCCGATCGTCGATCCCCGGCCCTATCATCC
CAATCGCTTCGCGGCCTCCGCCTGGGGCAAAGTCGCCGATTTCTAA

Upstream 100 bases:

>100_bases
CCAGCCTCCCGCCAAGACGGAATCTTCTGCTGTCGCTGGATGAACTCCGGCAAAGGCGCGGCGGTGAATCCGCTAAACTG
GCTGAAACGGAGACCATGCC

Downstream 100 bases:

>100_bases
AGAGGCGCGTCCCGGGGGAAAGACACGACGCGCCTCAGGAGGCCAAGGGCATCCGCCGATTGGCGAATTGTGACGCCCTG
CGGCCGTCTGCGGTCCGAAA

Product: deaminase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPAPLTRVDTTPQLPAAADAVVIGGGIVGVFAAYYLSRRGLKVALVEKGLIGAEQSSRNWGWCRQQNRDARELPMSTKSL
DLWERFATETGEDTGFRRCGLLYLSNSAEELSGWARWRDFARSVGVTTHMLSSAEATERGGATGTAWKGGVFSPTDGTAD
PARAAPAVARAILKLGGTVHQSCAARGIDIEGGRVSGVVTEHGMIRTKVAILAGGAWASAFCRQLGIRFPQASIRSSILS
VSPGASGLPDALHTSRVSVTRRADGGYTLAISGRGRVDPTAQQFRFAPQFLPMFARRWRSLAPGGLEGIRSGHESLARWR
LDRPTPMERMRILDPAVDEATIALTHARAIKLLPALKKAEINAAWAGYIDSTPDGVPGIGEIASLPGFILAAGFSGHGFG
IGPGAGHLIADIVTGDEPIVDPRPYHPNRFAASAWGKVADF

Sequences:

>Translated_441_residues
MPAPLTRVDTTPQLPAAADAVVIGGGIVGVFAAYYLSRRGLKVALVEKGLIGAEQSSRNWGWCRQQNRDARELPMSTKSL
DLWERFATETGEDTGFRRCGLLYLSNSAEELSGWARWRDFARSVGVTTHMLSSAEATERGGATGTAWKGGVFSPTDGTAD
PARAAPAVARAILKLGGTVHQSCAARGIDIEGGRVSGVVTEHGMIRTKVAILAGGAWASAFCRQLGIRFPQASIRSSILS
VSPGASGLPDALHTSRVSVTRRADGGYTLAISGRGRVDPTAQQFRFAPQFLPMFARRWRSLAPGGLEGIRSGHESLARWR
LDRPTPMERMRILDPAVDEATIALTHARAIKLLPALKKAEINAAWAGYIDSTPDGVPGIGEIASLPGFILAAGFSGHGFG
IGPGAGHLIADIVTGDEPIVDPRPYHPNRFAASAWGKVADF
>Mature_440_residues
PAPLTRVDTTPQLPAAADAVVIGGGIVGVFAAYYLSRRGLKVALVEKGLIGAEQSSRNWGWCRQQNRDARELPMSTKSLD
LWERFATETGEDTGFRRCGLLYLSNSAEELSGWARWRDFARSVGVTTHMLSSAEATERGGATGTAWKGGVFSPTDGTADP
ARAAPAVARAILKLGGTVHQSCAARGIDIEGGRVSGVVTEHGMIRTKVAILAGGAWASAFCRQLGIRFPQASIRSSILSV
SPGASGLPDALHTSRVSVTRRADGGYTLAISGRGRVDPTAQQFRFAPQFLPMFARRWRSLAPGGLEGIRSGHESLARWRL
DRPTPMERMRILDPAVDEATIALTHARAIKLLPALKKAEINAAWAGYIDSTPDGVPGIGEIASLPGFILAAGFSGHGFGI
GPGAGHLIADIVTGDEPIVDPRPYHPNRFAASAWGKVADF

Specific function: Unknown

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=437, Percent_Identity=25.858123569794, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI21361378, Length=437, Percent_Identity=25.858123569794, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI194306651, Length=424, Percent_Identity=22.1698113207547, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20130091, Length=422, Percent_Identity=24.8815165876777, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571104, Length=248, Percent_Identity=28.2258064516129, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 46795; Mature: 46664

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPLTRVDTTPQLPAAADAVVIGGGIVGVFAAYYLSRRGLKVALVEKGLIGAEQSSRNW
CCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCC
GWCRQQNRDARELPMSTKSLDLWERFATETGEDTGFRRCGLLYLSNSAEELSGWARWRDF
CHHHHCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECCCHHHHHHHHHHHHH
ARSVGVTTHMLSSAEATERGGATGTAWKGGVFSPTDGTADPARAAPAVARAILKLGGTVH
HHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
QSCAARGIDIEGGRVSGVVTEHGMIRTKVAILAGGAWASAFCRQLGIRFPQASIRSSILS
HHHHHCCCCCCCCEEEEEEECCCHHHEEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHC
VSPGASGLPDALHTSRVSVTRRADGGYTLAISGRGRVDPTAQQFRFAPQFLPMFARRWRS
CCCCCCCCCHHHHHHHEEEEEECCCCEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHH
LAPGGLEGIRSGHESLARWRLDRPTPMERMRILDPAVDEATIALTHARAIKLLPALKKAE
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHH
INAAWAGYIDSTPDGVPGIGEIASLPGFILAAGFSGHGFGIGPGAGHLIADIVTGDEPIV
CCCEEECCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCHHEEEEECCCCCCC
DPRPYHPNRFAASAWGKVADF
CCCCCCCCCHHHHHCCHHCCC
>Mature Secondary Structure 
PAPLTRVDTTPQLPAAADAVVIGGGIVGVFAAYYLSRRGLKVALVEKGLIGAEQSSRNW
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCC
GWCRQQNRDARELPMSTKSLDLWERFATETGEDTGFRRCGLLYLSNSAEELSGWARWRDF
CHHHHCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECCCHHHHHHHHHHHHH
ARSVGVTTHMLSSAEATERGGATGTAWKGGVFSPTDGTADPARAAPAVARAILKLGGTVH
HHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
QSCAARGIDIEGGRVSGVVTEHGMIRTKVAILAGGAWASAFCRQLGIRFPQASIRSSILS
HHHHHCCCCCCCCEEEEEEECCCHHHEEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHC
VSPGASGLPDALHTSRVSVTRRADGGYTLAISGRGRVDPTAQQFRFAPQFLPMFARRWRS
CCCCCCCCCHHHHHHHEEEEEECCCCEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHH
LAPGGLEGIRSGHESLARWRLDRPTPMERMRILDPAVDEATIALTHARAIKLLPALKKAE
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHH
INAAWAGYIDSTPDGVPGIGEIASLPGFILAAGFSGHGFGIGPGAGHLIADIVTGDEPIV
CCCEEECCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCHHEEEEECCCCCCC
DPRPYHPNRFAASAWGKVADF
CCCCCCCCCHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8682785; 10984043; 8097014 [H]