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The map label for this gene is argE

Identifier: 86361065

GI number: 86361065

Start: 376008

End: 377132

Strand: Direct

Name: argE

Synonym: RHE_PF00335

Alternate gene names: 86361065

Gene position: 376008-377132 (Clockwise)

Preceding gene: 86361063

Following gene: 86361066

Centisome position: 58.52

GC content: 65.24

Gene sequence:

>1125_bases
ATGCAGGCAATTGAAATCCTCGAAAGGTTGGTCGGCTTTCCCTCGGTCGTCGGCACGCCGAACGGCGAGATCGTTGGGTG
GATCAGGCATTACCTGCAAAGGCACGGTATTGTCGTCACGGAGATTGCCGGCCCCGAGGGCGACCGGTCGAACCTCTTCG
TAACGATAGGTCCAAGGGAGACGCCGGGTTACATCCTCTCCGGCCATATGGACGTCGTTCCCGCCACGGAAGGCGGGTGG
AGCAGCGATCCGTTCCGTCTCCGCGCCGAAACGGACCGCCTCTACGGTCGCGGAACCACCGACATGAAGGGCTTTCTCGC
CGTCGTGCTTGCCGCCGTCCCGGCACTCGCGGCGGCACAACTCCGCCGACCCATCCACCTCGCTCTTTCCTACGATGAGG
AGGCAGGCTGCCGCGGGGTCCCGCACATGATCGCCCGCCTGCCTGAGCTCTGTGCACCTCCGCTCGGCGCGATTATCGGC
GAACCGAGCGGCATGCGGGCGATCCGAGCGCACAAGGGCAAGGCGGCCGCTCGGCTGACGGTCAGAGGCCGGTCCGGCCA
TTCCTCGCGCCCCGACCGGGGACTAAATGCAATCCATGCCATGACCGACATCTTGGTTTGCGCCAGCGCCGAAGCCGAAC
GGCTGGCGCAGGGTCCGTTCGAACATGTTTTCGAACCGCCCTATTCCTCCCTCCAGGTCGGCACATTGAAGGGTGGCCAG
GCGGTCAACATCATTCCCGATAGCTGCGAAGCCGAGTTCGAGGCGAGGGCTATTTCCGGAATCGACCCGGCCACGCTGCT
GGCGCCGCTGCGAACGATGGCCGACGCACTGCGGCAACGCGGCTTTCAGTCGGAATGGCGCGAACTCAGCGCCTATCCGG
CGCTGTCGCTTGCCGCCGATGCGCCGCTTGCACGCTTGCTTGGCGAACTCACCGGTGTCGAGCCACTCGCCGCCGTCAGC
TACGGCACCGAGGCCGGTCTTTTCCAGCGCGCAGGCATCGATGCGATCATCTGCGGGCCGGGCGATATCGCCCGTGCTCA
CCGACCGGACGAATTCATCCTCGCGAACGAACTCCTGGCCTGCCAGGCGATGATCGAGGCACTCGCCCGACGTTGCATCG
CCTGA

Upstream 100 bases:

>100_bases
GCCGGGTCTCTACAGTCATCGGCCAGATCCCGACCGCCGCCCGTACCTTTGACCGCGAGTGGGCCGGTGCAATTCTATAT
CCCGCGATGCGAGGAAGCTC

Downstream 100 bases:

>100_bases
CCGTCAGATCAAGGAGCCGATGCAATGACCTTTCTCTTCAATTCCGATGCGAAGCGCGGCGCTATATTCGCCGAGGCCTT
CGCGCGCGAACTGCCCGACA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MQAIEILERLVGFPSVVGTPNGEIVGWIRHYLQRHGIVVTEIAGPEGDRSNLFVTIGPRETPGYILSGHMDVVPATEGGW
SSDPFRLRAETDRLYGRGTTDMKGFLAVVLAAVPALAAAQLRRPIHLALSYDEEAGCRGVPHMIARLPELCAPPLGAIIG
EPSGMRAIRAHKGKAAARLTVRGRSGHSSRPDRGLNAIHAMTDILVCASAEAERLAQGPFEHVFEPPYSSLQVGTLKGGQ
AVNIIPDSCEAEFEARAISGIDPATLLAPLRTMADALRQRGFQSEWRELSAYPALSLAADAPLARLLGELTGVEPLAAVS
YGTEAGLFQRAGIDAIICGPGDIARAHRPDEFILANELLACQAMIEALARRCIA

Sequences:

>Translated_374_residues
MQAIEILERLVGFPSVVGTPNGEIVGWIRHYLQRHGIVVTEIAGPEGDRSNLFVTIGPRETPGYILSGHMDVVPATEGGW
SSDPFRLRAETDRLYGRGTTDMKGFLAVVLAAVPALAAAQLRRPIHLALSYDEEAGCRGVPHMIARLPELCAPPLGAIIG
EPSGMRAIRAHKGKAAARLTVRGRSGHSSRPDRGLNAIHAMTDILVCASAEAERLAQGPFEHVFEPPYSSLQVGTLKGGQ
AVNIIPDSCEAEFEARAISGIDPATLLAPLRTMADALRQRGFQSEWRELSAYPALSLAADAPLARLLGELTGVEPLAAVS
YGTEAGLFQRAGIDAIICGPGDIARAHRPDEFILANELLACQAMIEALARRCIA
>Mature_374_residues
MQAIEILERLVGFPSVVGTPNGEIVGWIRHYLQRHGIVVTEIAGPEGDRSNLFVTIGPRETPGYILSGHMDVVPATEGGW
SSDPFRLRAETDRLYGRGTTDMKGFLAVVLAAVPALAAAQLRRPIHLALSYDEEAGCRGVPHMIARLPELCAPPLGAIIG
EPSGMRAIRAHKGKAAARLTVRGRSGHSSRPDRGLNAIHAMTDILVCASAEAERLAQGPFEHVFEPPYSSLQVGTLKGGQ
AVNIIPDSCEAEFEARAISGIDPATLLAPLRTMADALRQRGFQSEWRELSAYPALSLAADAPLARLLGELTGVEPLAAVS
YGTEAGLFQRAGIDAIICGPGDIARAHRPDEFILANELLACQAMIEALARRCIA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=223, Percent_Identity=29.5964125560538, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1790395, Length=363, Percent_Identity=31.6804407713499, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788816, Length=345, Percent_Identity=25.5072463768116, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551016, Length=385, Percent_Identity=25.974025974026, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 39892; Mature: 39892

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIEILERLVGFPSVVGTPNGEIVGWIRHYLQRHGIVVTEIAGPEGDRSNLFVTIGPRE
CCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCC
TPGYILSGHMDVVPATEGGWSSDPFRLRAETDRLYGRGTTDMKGFLAVVLAAVPALAAAQ
CCCEEEECCEEEEECCCCCCCCCCEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LRRPIHLALSYDEEAGCRGVPHMIARLPELCAPPLGAIIGEPSGMRAIRAHKGKAAARLT
HCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHCCCCCEEEEE
VRGRSGHSSRPDRGLNAIHAMTDILVCASAEAERLAQGPFEHVFEPPYSSLQVGTLKGGQ
EECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHCCCCCCCEEEEEECCCC
AVNIIPDSCEAEFEARAISGIDPATLLAPLRTMADALRQRGFQSEWRELSAYPALSLAAD
EEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCC
APLARLLGELTGVEPLAAVSYGTEAGLFQRAGIDAIICGPGDIARAHRPDEFILANELLA
CHHHHHHHHHCCCCHHHHHHCCCCCCHHHHCCCCEEEECCCHHHHCCCCCHHHHHHHHHH
CQAMIEALARRCIA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MQAIEILERLVGFPSVVGTPNGEIVGWIRHYLQRHGIVVTEIAGPEGDRSNLFVTIGPRE
CCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCC
TPGYILSGHMDVVPATEGGWSSDPFRLRAETDRLYGRGTTDMKGFLAVVLAAVPALAAAQ
CCCEEEECCEEEEECCCCCCCCCCEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LRRPIHLALSYDEEAGCRGVPHMIARLPELCAPPLGAIIGEPSGMRAIRAHKGKAAARLT
HCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHCCCCCEEEEE
VRGRSGHSSRPDRGLNAIHAMTDILVCASAEAERLAQGPFEHVFEPPYSSLQVGTLKGGQ
EECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHCCCCCCCEEEEEECCCC
AVNIIPDSCEAEFEARAISGIDPATLLAPLRTMADALRQRGFQSEWRELSAYPALSLAAD
EEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHCC
APLARLLGELTGVEPLAAVSYGTEAGLFQRAGIDAIICGPGDIARAHRPDEFILANELLA
CHHHHHHHHHCCCCHHHHHHCCCCCCHHHHCCCCEEEECCCHHHHCCCCCHHHHHHHHHH
CQAMIEALARRCIA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10692366 [H]