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The map label for this gene is endR [H]

Identifier: 86360986

GI number: 86360986

Start: 274051

End: 275121

Strand: Direct

Name: endR [H]

Synonym: RHE_PF00256

Alternate gene names: 86360986

Gene position: 274051-275121 (Clockwise)

Preceding gene: 86360981

Following gene: 86360990

Centisome position: 42.65

GC content: 63.12

Gene sequence:

>1071_bases
ATGGAAGATTCCGCTGGTCCGAAACGTTCAGTCACGGTCGCCGACGTCGCGAAGGCGGCACGGGTGTCGAAAGCGACGGC
CGCCCGCGTGCTTGGAGGCTACGGCGTCGTCAGCGACAAGATCAAGGATCAGGTCATGGCGGCGGCGGCCGCACTCGAAT
ACCGGCCGAACGAACTTGCGCGAAGCATGAGCACTGGCCGGTCCGGCATCATCGGGATCGTCGTCGGCGATATCGAAAAT
GCGTTCTTCAGTCTGGCAGTGCGCGGCATCAGCGATGCGGCTCGGCTCGCAGGCTTCGACGTGATCATTTCCAATTCGGG
CGAGAAGCTCGAAGCGGAGAAATCAGCCGTCGACCTCCTGATCGGCAAGCGTGTCGATGGCTTGATTGTCACGCCCGCCC
GCTGCGACAGCATCGAACATCTCCGGCATGTCGGCCGCGCCGGTATGCCGCTGGTCCTCTTCGACCGGAGTATCCCGGAG
CTCGCTGTCGACGCCGTGACCGGCGATGATCGCGAGGCCGCCATCGCCGCCGCCCGGTTTATGGTCGAGGCGGGACATCG
ACGTCTCGCTTACGTCTCGGCCATGGACCCCGAAGGCGACGGCCTCACCGATCTCACGCGGATATCGAATTCTGCCGTGC
GTGAACGCGTGGAGGGCTTCGTCAGCGTCCTGACGGAGGCAGGCTTGCCCAGTCCCCTTCACTATGTGCGGCTCGGTGCG
ACCGACCAAGCGCAGACGGACGCCGTGATGAAACGTCTGCTCTCGGACCCATCGCCGCCAACGGCGATCCTCGCATCGGA
TAGCCTGGTGGGGCTGCGCGTCTTCAAGTCGCTGCAATCACTCGGCCTCTCAATTCCCGACGATATCTCGATGATTTCCT
TCCTGGATGCCGATTGGACAAGCGTTACCGTTCCCCCGATTACCGTCGTCGATCAGCGCGTTTACGAGATGGGCAAACTC
GCCGGCGAGCGGCTCGTCGCCCGCATTGAACAGATCCCCCTTGCCGTTGAACGGCTGCGAGTCAGCACCAGCCTCGTCAT
ACGCAGTTCGGTCGCAAGGATTGGCCGGTGA

Upstream 100 bases:

>100_bases
CCCGCAATGATACCGGTCTCCAATCAAAAGAGACCGGTCTCACGACAGATTTGATAACTGTCAATTGACCGCCCGTCAAC
AACTCTTGTAGTGCTGCGGC

Downstream 100 bases:

>100_bases
GTTTGGTCCTAAGCAGGATGTGAAGCGAGGTCTAATCGAAAAGTTCACCGTGGCCAATCTGCTCCCGCTTGCCTGGCACG
TCGCTAATCGCGGGGTCGTC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MEDSAGPKRSVTVADVAKAARVSKATAARVLGGYGVVSDKIKDQVMAAAAALEYRPNELARSMSTGRSGIIGIVVGDIEN
AFFSLAVRGISDAARLAGFDVIISNSGEKLEAEKSAVDLLIGKRVDGLIVTPARCDSIEHLRHVGRAGMPLVLFDRSIPE
LAVDAVTGDDREAAIAAARFMVEAGHRRLAYVSAMDPEGDGLTDLTRISNSAVRERVEGFVSVLTEAGLPSPLHYVRLGA
TDQAQTDAVMKRLLSDPSPPTAILASDSLVGLRVFKSLQSLGLSIPDDISMISFLDADWTSVTVPPITVVDQRVYEMGKL
AGERLVARIEQIPLAVERLRVSTSLVIRSSVARIGR

Sequences:

>Translated_356_residues
MEDSAGPKRSVTVADVAKAARVSKATAARVLGGYGVVSDKIKDQVMAAAAALEYRPNELARSMSTGRSGIIGIVVGDIEN
AFFSLAVRGISDAARLAGFDVIISNSGEKLEAEKSAVDLLIGKRVDGLIVTPARCDSIEHLRHVGRAGMPLVLFDRSIPE
LAVDAVTGDDREAAIAAARFMVEAGHRRLAYVSAMDPEGDGLTDLTRISNSAVRERVEGFVSVLTEAGLPSPLHYVRLGA
TDQAQTDAVMKRLLSDPSPPTAILASDSLVGLRVFKSLQSLGLSIPDDISMISFLDADWTSVTVPPITVVDQRVYEMGKL
AGERLVARIEQIPLAVERLRVSTSLVIRSSVARIGR
>Mature_356_residues
MEDSAGPKRSVTVADVAKAARVSKATAARVLGGYGVVSDKIKDQVMAAAAALEYRPNELARSMSTGRSGIIGIVVGDIEN
AFFSLAVRGISDAARLAGFDVIISNSGEKLEAEKSAVDLLIGKRVDGLIVTPARCDSIEHLRHVGRAGMPLVLFDRSIPE
LAVDAVTGDDREAAIAAARFMVEAGHRRLAYVSAMDPEGDGLTDLTRISNSAVRERVEGFVSVLTEAGLPSPLHYVRLGA
TDQAQTDAVMKRLLSDPSPPTAILASDSLVGLRVFKSLQSLGLSIPDDISMISFLDADWTSVTVPPITVVDQRVYEMGKL
AGERLVARIEQIPLAVERLRVSTSLVIRSSVARIGR

Specific function: Putative repressor of the endoglucanase operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=344, Percent_Identity=29.6511627906977, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790194, Length=341, Percent_Identity=27.8592375366569, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788474, Length=313, Percent_Identity=31.9488817891374, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787948, Length=347, Percent_Identity=25.6484149855908, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789202, Length=350, Percent_Identity=27.1428571428571, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789068, Length=310, Percent_Identity=27.4193548387097, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787906, Length=332, Percent_Identity=25.6024096385542, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=27.2445820433437, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787580, Length=345, Percent_Identity=23.768115942029, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786268, Length=321, Percent_Identity=24.2990654205607, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786540, Length=321, Percent_Identity=25.8566978193146, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790715, Length=329, Percent_Identity=19.4528875379939, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37855; Mature: 37855

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDSAGPKRSVTVADVAKAARVSKATAARVLGGYGVVSDKIKDQVMAAAAALEYRPNELA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHH
RSMSTGRSGIIGIVVGDIENAFFSLAVRGISDAARLAGFDVIISNSGEKLEAEKSAVDLL
HHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
IGKRVDGLIVTPARCDSIEHLRHVGRAGMPLVLFDRSIPELAVDAVTGDDREAAIAAARF
HCCCCCCEEECCHHCCHHHHHHHHCCCCCCEEEECCCCCHHHHECCCCCCHHHHHHHHHH
MVEAGHRRLAYVSAMDPEGDGLTDLTRISNSAVRERVEGFVSVLTEAGLPSPLHYVRLGA
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
TDQAQTDAVMKRLLSDPSPPTAILASDSLVGLRVFKSLQSLGLSIPDDISMISFLDADWT
CCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
SVTVPPITVVDQRVYEMGKLAGERLVARIEQIPLAVERLRVSTSLVIRSSVARIGR
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEDSAGPKRSVTVADVAKAARVSKATAARVLGGYGVVSDKIKDQVMAAAAALEYRPNELA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHH
RSMSTGRSGIIGIVVGDIENAFFSLAVRGISDAARLAGFDVIISNSGEKLEAEKSAVDLL
HHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
IGKRVDGLIVTPARCDSIEHLRHVGRAGMPLVLFDRSIPELAVDAVTGDDREAAIAAARF
HCCCCCCEEECCHHCCHHHHHHHHCCCCCCEEEECCCCCHHHHECCCCCCHHHHHHHHHH
MVEAGHRRLAYVSAMDPEGDGLTDLTRISNSAVRERVEGFVSVLTEAGLPSPLHYVRLGA
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
TDQAQTDAVMKRLLSDPSPPTAILASDSLVGLRVFKSLQSLGLSIPDDISMISFLDADWT
CCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
SVTVPPITVVDQRVYEMGKLAGERLVARIEQIPLAVERLRVSTSLVIRSSVARIGR
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2307659; 1639817 [H]