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The map label for this gene is thuR

Identifier: 86360942

GI number: 86360942

Start: 222246

End: 223259

Strand: Direct

Name: thuR

Synonym: RHE_PF00211

Alternate gene names: 86360942

Gene position: 222246-223259 (Clockwise)

Preceding gene: 86360935

Following gene: 86360949

Centisome position: 34.59

GC content: 60.95

Gene sequence:

>1014_bases
ATGAAACTTCGTGAATTTGCAAAGCAGCTTGGGCTTTCTCCGACGACGGTCAGCCGTGCGCTCAGCGGCTACCCGGAGGT
CAGCGAAGCCACGCGTGCCCGGGTTGCAAGCGAAGCAACGCGGCTTGGCTATCGCCCCGATATCAATGCCGTGCGGCTAA
AGACCGGAAGAGCCGGAGCGATCGGCGTGATGATGGCGCGGTCGGGAGAAATCCATTTCGCTGAATTCATGTCGGGCATG
GCGCAGCGCCTGGAAACGGCCGATACCGATATTCTCATCACGCCCATCACCGCGCATAATGACGACGACGAGATCCAGGC
CTACAGACGCCTGGTCGAAAGCCGCCGCGTGGATGCAGTGATCATTCACTCACCTCGTCCTCGGGACCCGCGGATCGAGA
TGCTGAGTAGCCTGCGTCTGCCTTTCCTGGTTCACGGCCGGTCGGAGACGGAGCACGTTCACGCCTGGCTTGATATCGAT
AATGAAAATGCGGTGCGCAGGTCCACCGAACACCTGCTCGATCTCGGGCACCGCCGCATCGCCATGATCAATGGCCTCAG
GGGCAAGACTTATTCGATCCATCGCGAACAGGGTTTTCGGCTCGCCCATCAGGAGCGTGGACTCATCGCCGACCCCAACA
TGATGATCTGCGATAAATTCTCCGACGAGAGCGGCTTTCGCCATGCCCGCTCCTTCCTCGAGAGAGCAAATGCACCGACC
GCCATCGTCGCCGGTTCCACGATGACGGCGCTTGGGGTTTACCGCGCCGTCCGCTCGCTCGGGATGACGGTGGGACAGGA
TGTTTCCGTCATCGCCCATGACGACGTCTTCCCTTATCTGACGGCCGAAAACATGGTGCCGTCGCTCTCGACAACCCGAT
CTTCCATGCGTGCTGCGGGCACACGCTGCGCCGAACTGACGCTGCAGCTGATCGCCGGACGCGCCGCTGAGGAGGTCCAT
GAATTATGGCCGGTCGAGCTGATCCTACGAGAAAGCACTGCGCCGCCGCGCTGA

Upstream 100 bases:

>100_bases
CTTAATTGAAATCGATTTCAATTATCATCTGATTGGCCACGTGCCCGTTGCGCATCGCCAACGCATCGTCCATTGATTGC
CTGGACAAAGAAGACATCCG

Downstream 100 bases:

>100_bases
CTGGGCGGCTCCTGTCGCCGAGACCTTTCGTCCAGCCGCCAATCGGACTGGAAGCAGGTGAGTTTACCAGATGAGGCAAC
GGCGCAACTGCGCTGTAGCT

Product: trehalose/maltose transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKLREFAKQLGLSPTTVSRALSGYPEVSEATRARVASEATRLGYRPDINAVRLKTGRAGAIGVMMARSGEIHFAEFMSGM
AQRLETADTDILITPITAHNDDDEIQAYRRLVESRRVDAVIIHSPRPRDPRIEMLSSLRLPFLVHGRSETEHVHAWLDID
NENAVRRSTEHLLDLGHRRIAMINGLRGKTYSIHREQGFRLAHQERGLIADPNMMICDKFSDESGFRHARSFLERANAPT
AIVAGSTMTALGVYRAVRSLGMTVGQDVSVIAHDDVFPYLTAENMVPSLSTTRSSMRAAGTRCAELTLQLIAGRAAEEVH
ELWPVELILRESTAPPR

Sequences:

>Translated_337_residues
MKLREFAKQLGLSPTTVSRALSGYPEVSEATRARVASEATRLGYRPDINAVRLKTGRAGAIGVMMARSGEIHFAEFMSGM
AQRLETADTDILITPITAHNDDDEIQAYRRLVESRRVDAVIIHSPRPRDPRIEMLSSLRLPFLVHGRSETEHVHAWLDID
NENAVRRSTEHLLDLGHRRIAMINGLRGKTYSIHREQGFRLAHQERGLIADPNMMICDKFSDESGFRHARSFLERANAPT
AIVAGSTMTALGVYRAVRSLGMTVGQDVSVIAHDDVFPYLTAENMVPSLSTTRSSMRAAGTRCAELTLQLIAGRAAEEVH
ELWPVELILRESTAPPR
>Mature_337_residues
MKLREFAKQLGLSPTTVSRALSGYPEVSEATRARVASEATRLGYRPDINAVRLKTGRAGAIGVMMARSGEIHFAEFMSGM
AQRLETADTDILITPITAHNDDDEIQAYRRLVESRRVDAVIIHSPRPRDPRIEMLSSLRLPFLVHGRSETEHVHAWLDID
NENAVRRSTEHLLDLGHRRIAMINGLRGKTYSIHREQGFRLAHQERGLIADPNMMICDKFSDESGFRHARSFLERANAPT
AIVAGSTMTALGVYRAVRSLGMTVGQDVSVIAHDDVFPYLTAENMVPSLSTTRSSMRAAGTRCAELTLQLIAGRAAEEVH
ELWPVELILRESTAPPR

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=325, Percent_Identity=26.4615384615385, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790369, Length=332, Percent_Identity=26.8072289156627, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789068, Length=295, Percent_Identity=28.4745762711864, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786540, Length=341, Percent_Identity=26.099706744868, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=21.6300940438871, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790194, Length=294, Percent_Identity=26.8707482993197, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788474, Length=335, Percent_Identity=27.1641791044776, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789202, Length=335, Percent_Identity=25.6716417910448, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787906, Length=288, Percent_Identity=23.6111111111111, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI48994940, Length=321, Percent_Identity=24.2990654205607, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37498; Mature: 37498

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLREFAKQLGLSPTTVSRALSGYPEVSEATRARVASEATRLGYRPDINAVRLKTGRAGA
CCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCE
IGVMMARSGEIHFAEFMSGMAQRLETADTDILITPITAHNDDDEIQAYRRLVESRRVDAV
EEEEEECCCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEE
IIHSPRPRDPRIEMLSSLRLPFLVHGRSETEHVHAWLDIDNENAVRRSTEHLLDLGHRRI
EEECCCCCCHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCHHE
AMINGLRGKTYSIHREQGFRLAHQERGLIADPNMMICDKFSDESGFRHARSFLERANAPT
EEEECCCCCEEEEEHHCCCCHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCE
AIVAGSTMTALGVYRAVRSLGMTVGQDVSVIAHDDVFPYLTAENMVPSLSTTRSSMRAAG
EEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEHHHCCCCHHHHHHHHHHHH
TRCAELTLQLIAGRAAEEVHELWPVELILRESTAPPR
HHHHHHHHHHHHCHHHHHHHHHCCHHHEEECCCCCCC
>Mature Secondary Structure
MKLREFAKQLGLSPTTVSRALSGYPEVSEATRARVASEATRLGYRPDINAVRLKTGRAGA
CCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCE
IGVMMARSGEIHFAEFMSGMAQRLETADTDILITPITAHNDDDEIQAYRRLVESRRVDAV
EEEEEECCCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEE
IIHSPRPRDPRIEMLSSLRLPFLVHGRSETEHVHAWLDIDNENAVRRSTEHLLDLGHRRI
EEECCCCCCHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCHHE
AMINGLRGKTYSIHREQGFRLAHQERGLIADPNMMICDKFSDESGFRHARSFLERANAPT
EEEECCCCCEEEEEHHCCCCHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCE
AIVAGSTMTALGVYRAVRSLGMTVGQDVSVIAHDDVFPYLTAENMVPSLSTTRSSMRAAG
EEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEHHHCCCCHHHHHHHHHHHH
TRCAELTLQLIAGRAAEEVHELWPVELILRESTAPPR
HHHHHHHHHHHHCHHHHHHHHHCCHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]