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The map label for this gene is des [H]

Identifier: 86360863

GI number: 86360863

Start: 139259

End: 140323

Strand: Direct

Name: des [H]

Synonym: RHE_PF00132

Alternate gene names: 86360863

Gene position: 139259-140323 (Clockwise)

Preceding gene: 86360862

Following gene: 86360864

Centisome position: 21.67

GC content: 57.75

Gene sequence:

>1065_bases
ATGAGAAGCCAAGCCGGCCAGTTGCACGAGCCGTTTGAAGACTCCGCCGGTGCGTGGCTGAAGATCCTCGCGAAATACCG
GCAACCGAGCTTTTGGCGCAGCGCGTTCGAGTTGTCTGTGACAGCTGTCCCGTTCGCGCTGCTATGGGTCGGCGCGTATG
CCTCTTTGCTGCAAGACTTTTGGCCCGGCTACATACTGATCCTGCCAGCCGCCGCCTTCCTGCTCCGGTTATTCATGATC
CAGCACGATTGCGGGCACGGTTCATTCTTCGCCCGGCGAAAGCTGGATACGTGGACAGGAAGGGCACTCGGCGTTTTGAC
ACTAACGCCTTACGATTATTGGCGGCAAACACATGCCGAACATCATGCATCTGCTGGCAATCTTGATAAGCGTGGCATCG
GCGACATCACGACCTTGACGCTCGAGGAATACCGCGCCCGTTCTCGAACCGGGCGACTCGCCTACCGACTTTACAGGCAT
CCGATCGTCATGTTTGGCATTGGACCCGCCTGGCTCTTTATCTTCAAGCAACGCCTGCCGATCGGGATGATGCAAGCGGG
AGCCCTGCCTTGGGTTTCCACGATGGCCACGAATGTAGCGATCGCGATCGTAGGCGGCCTGGTAATATGGGCGATTGGAC
CTATCCCCTTCCTGCTGGTTCATCTGCCCGTCGTTCTGCTGGCAGGGGCAGCCGGCGTCTGGCTATTTTATGTCCAACAT
CAGTTCGAGGAAACGCACTGGTCGAAGACCGGAGAATGGAAATTTCCGCAGGCCGCTCTTCACGGCGCGTCACATTACGA
TCTTCCGCTCGTGCTTCGATGGCTGACCGGGAATATCGGTATCCACCATATCCACCATCTTTCAAGCCGCATTCCGTATT
ACCGGCTTCCGGAAGTCCTGCGCAATCACCCCGAGTTGGTGGCCATTGGCCGCGTCACCCTTTGGCAAAGCCTCGAATGT
GTCCGGCTTGCTTTATGGGATGAACAGAGCGGCAGGCTCATCTCCTTCCGCGAGGCCGAGAGCCTCGGCCCGTCGATATC
TGACCGCTTTATGCGGTTCGTTTGA

Upstream 100 bases:

>100_bases
CGCTATGCCGCGCGTAAGGCTCGTCGCGCTTGACGGCCGGAACATCCGACCGTGGCTCCCGCAAATTTGCATCGTCGTCC
AAAAGGAAATCAGAAAACCT

Downstream 100 bases:

>100_bases
ATAGCATGTTAGGATCCAAGATGATTGCCACCGCTAAAATAAGTCCCAATACGGCCGCTTTGAGGGTCACTTTGACGCCT
CCCCAGATCAGAGGCCTGAA

Product: fatty acid desaturase protein

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MRSQAGQLHEPFEDSAGAWLKILAKYRQPSFWRSAFELSVTAVPFALLWVGAYASLLQDFWPGYILILPAAAFLLRLFMI
QHDCGHGSFFARRKLDTWTGRALGVLTLTPYDYWRQTHAEHHASAGNLDKRGIGDITTLTLEEYRARSRTGRLAYRLYRH
PIVMFGIGPAWLFIFKQRLPIGMMQAGALPWVSTMATNVAIAIVGGLVIWAIGPIPFLLVHLPVVLLAGAAGVWLFYVQH
QFEETHWSKTGEWKFPQAALHGASHYDLPLVLRWLTGNIGIHHIHHLSSRIPYYRLPEVLRNHPELVAIGRVTLWQSLEC
VRLALWDEQSGRLISFREAESLGPSISDRFMRFV

Sequences:

>Translated_354_residues
MRSQAGQLHEPFEDSAGAWLKILAKYRQPSFWRSAFELSVTAVPFALLWVGAYASLLQDFWPGYILILPAAAFLLRLFMI
QHDCGHGSFFARRKLDTWTGRALGVLTLTPYDYWRQTHAEHHASAGNLDKRGIGDITTLTLEEYRARSRTGRLAYRLYRH
PIVMFGIGPAWLFIFKQRLPIGMMQAGALPWVSTMATNVAIAIVGGLVIWAIGPIPFLLVHLPVVLLAGAAGVWLFYVQH
QFEETHWSKTGEWKFPQAALHGASHYDLPLVLRWLTGNIGIHHIHHLSSRIPYYRLPEVLRNHPELVAIGRVTLWQSLEC
VRLALWDEQSGRLISFREAESLGPSISDRFMRFV
>Mature_354_residues
MRSQAGQLHEPFEDSAGAWLKILAKYRQPSFWRSAFELSVTAVPFALLWVGAYASLLQDFWPGYILILPAAAFLLRLFMI
QHDCGHGSFFARRKLDTWTGRALGVLTLTPYDYWRQTHAEHHASAGNLDKRGIGDITTLTLEEYRARSRTGRLAYRLYRH
PIVMFGIGPAWLFIFKQRLPIGMMQAGALPWVSTMATNVAIAIVGGLVIWAIGPIPFLLVHLPVVLLAGAAGVWLFYVQH
QFEETHWSKTGEWKFPQAALHGASHYDLPLVLRWLTGNIGIHHIHHLSSRIPYYRLPEVLRNHPELVAIGRVTLWQSLEC
VRLALWDEQSGRLISFREAESLGPSISDRFMRFV

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 40270; Mature: 40270

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSQAGQLHEPFEDSAGAWLKILAKYRQPSFWRSAFELSVTAVPFALLWVGAYASLLQDF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPGYILILPAAAFLLRLFMIQHDCGHGSFFARRKLDTWTGRALGVLTLTPYDYWRQTHAE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHH
HHASAGNLDKRGIGDITTLTLEEYRARSRTGRLAYRLYRHPIVMFGIGPAWLFIFKQRLP
HHCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHCC
IGMMQAGALPWVSTMATNVAIAIVGGLVIWAIGPIPFLLVHLPVVLLAGAAGVWLFYVQH
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
QFEETHWSKTGEWKFPQAALHGASHYDLPLVLRWLTGNIGIHHIHHLSSRIPYYRLPEVL
HHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
RNHPELVAIGRVTLWQSLECVRLALWDEQSGRLISFREAESLGPSISDRFMRFV
HCCCCEEEECHHHHHHHHHHHHHEEECCCCCCEEEEHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure
MRSQAGQLHEPFEDSAGAWLKILAKYRQPSFWRSAFELSVTAVPFALLWVGAYASLLQDF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPGYILILPAAAFLLRLFMIQHDCGHGSFFARRKLDTWTGRALGVLTLTPYDYWRQTHAE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHH
HHASAGNLDKRGIGDITTLTLEEYRARSRTGRLAYRLYRHPIVMFGIGPAWLFIFKQRLP
HHCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHCC
IGMMQAGALPWVSTMATNVAIAIVGGLVIWAIGPIPFLLVHLPVVLLAGAAGVWLFYVQH
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
QFEETHWSKTGEWKFPQAALHGASHYDLPLVLRWLTGNIGIHHIHHLSSRIPYYRLPEVL
HHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
RNHPELVAIGRVTLWQSLECVRLALWDEQSGRLISFREAESLGPSISDRFMRFV
HCCCCEEEECHHHHHHHHHHHHHEEECCCCCCEEEEHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]