Click here to switch to the map view.

The map label for this gene is siaT [H]

Identifier: 86360803

GI number: 86360803

Start: 69618

End: 71024

Strand: Direct

Name: siaT [H]

Synonym: RHE_PF00070

Alternate gene names: 86360803

Gene position: 69618-71024 (Clockwise)

Preceding gene: 86360802

Following gene: 86360804

Centisome position: 10.84

GC content: 61.98

Gene sequence:

>1407_bases
ATGCTGCTGCTTCTTGGCTCGTTTCTGCTGCTGATGCTGGTCGGCGTGCCCGTCGCCATTTCGATGGCCGTCGCCTCCGT
GCTTTACATCGTCCTTTACGGCGTGGCGCCCGACATCATCGTCGCCCAGCGCATGATCGCCGGCGTCGAAAGTTTTCCCC
TGCTCGCCGTGCCCTTCTTCATTCTGGCGGGCAATCTGATGAACTCGGCGGGTGTGACCGGCCGCATCTACTCCTTTGCG
GTCGCCCTAGTCGGGTGGATGAAGGGCGGGCTGGCGCAGGTCAATATCATCGGCTCCGTCATCTTCTCCGGCATGTCGGG
CACCGCGCTCGCAGACGCCGCCGGCATCGGCACGATCGAAATCAAGGCAATGAAGGACCACGGCTATCCGGTCGAAGCGG
CGGTCGGCGTCACGGCGGCCTCCGCCACGCTCGGCCCGATCTTTCCCCCGTCGCTGCCCTTCGTCATCTACGGCATGATG
GCGAACGTCTCGATCGGCGCTCTGTTCATGGCCGGTATCCTGCCCGGCGTCGTCATGACGCTGCTGATGATGATCACCGT
CGCCGCCTTCGCCTATCGCAAACGCTGGGGCTCGGACGCACCGTTCAATGTGCGCGAGCTCCTGTCGGCCGGCATGGAAA
TCGTCGTTGTCCTGATGGTGCCTGTGGCGATCTATCTGATGATGCGCGCCGGTCTTTCGATGAACGCCGCGGCGGGTATT
GCCCTCCTCGTGCTTCTGGCGCTCGACTGGTATTTCGGCTTCTCCGCCGTCATGGCGCTGATGACCCCGGTTATCCTGAT
CGGCGGCATGACGATGGGCTGGTTCACGCCGACCGAAGCCGCGGTCGCGGCCGTGCTCTGGTCGCTCTTCCTCGGCCTCG
TGCGCTACCGCACGATGACGCTCTCGACACTCGCCAAGGCGAGCTTCGATACGATCGAGACGACGGCATCCGTTCTCTTC
ATTGTCACCGCGGCTTCCGTCTTCGCATGGCTCTTGACGGCCAGCCAGGCCGCGCAGCTGCTTTCCGATGCGATCCTGTC
GATCACCGACAATAAATGGGTGTTCCTGATCCTGGTGAACCTGCTGATGCTGTTCGTCGGCTGCTTCCTGGATACGATCG
CGGCGATCACCATCCTCGTGCCGATTCTGCTGCCGATCGTCGCCAAGTTCGATATCGACCCGGTTCAGTTTGGCCTGATC
ATGACGCTGAACCTGATGATCGGCCTGTTGCATCCGCCGCTCGGCATGGTGCTTTTCGTGCTGTCCAGAGTGGCGAAACT
CTCGGTCGAACGCACCACCATGGCAATCGTGCCCTGGTTGGTGCCGCTCTTCCTGGCATTGATCCTGATCACCTTCATTC
CCGCCGTATCGCTCTGGCTGCCGCAGCAACTCGGACTGTTGAGATAG

Upstream 100 bases:

>100_bases
ATGCTGATCCGCGCCGTGATCGTCTTCATCGCCAATATGCGCCGTGGCTACTCCGTCCTGGAGCGCCCGGAAGAATTCCA
ATCCGTCGAAGGATGACCCG

Downstream 100 bases:

>100_bases
GATGGCCATGATGCGAACACGTCTGGCACGGCTTTACCAAAAGGGCGATCTCAGGATCGAGGCCGACACCGTTGCGCCCC
CCGGTCCGGGCCAGGTGCTG

Product: C4-dicarboxylate ABC transporter permease

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MLLLLGSFLLLMLVGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFFILAGNLMNSAGVTGRIYSFA
VALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIEIKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMM
ANVSIGALFMAGILPGVVMTLLMMITVAAFAYRKRWGSDAPFNVRELLSAGMEIVVVLMVPVAIYLMMRAGLSMNAAAGI
ALLVLLALDWYFGFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMTLSTLAKASFDTIETTASVLF
IVTAASVFAWLLTASQAAQLLSDAILSITDNKWVFLILVNLLMLFVGCFLDTIAAITILVPILLPIVAKFDIDPVQFGLI
MTLNLMIGLLHPPLGMVLFVLSRVAKLSVERTTMAIVPWLVPLFLALILITFIPAVSLWLPQQLGLLR

Sequences:

>Translated_468_residues
MLLLLGSFLLLMLVGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFFILAGNLMNSAGVTGRIYSFA
VALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIEIKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMM
ANVSIGALFMAGILPGVVMTLLMMITVAAFAYRKRWGSDAPFNVRELLSAGMEIVVVLMVPVAIYLMMRAGLSMNAAAGI
ALLVLLALDWYFGFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMTLSTLAKASFDTIETTASVLF
IVTAASVFAWLLTASQAAQLLSDAILSITDNKWVFLILVNLLMLFVGCFLDTIAAITILVPILLPIVAKFDIDPVQFGLI
MTLNLMIGLLHPPLGMVLFVLSRVAKLSVERTTMAIVPWLVPLFLALILITFIPAVSLWLPQQLGLLR
>Mature_468_residues
MLLLLGSFLLLMLVGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFFILAGNLMNSAGVTGRIYSFA
VALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIEIKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMM
ANVSIGALFMAGILPGVVMTLLMMITVAAFAYRKRWGSDAPFNVRELLSAGMEIVVVLMVPVAIYLMMRAGLSMNAAAGI
ALLVLLALDWYFGFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMTLSTLAKASFDTIETTASVLF
IVTAASVFAWLLTASQAAQLLSDAILSITDNKWVFLILVNLLMLFVGCFLDTIAAITILVPILLPIVAKFDIDPVQFGLI
MTLNLMIGLLHPPLGMVLFVLSRVAKLSVERTTMAIVPWLVPLFLALILITFIPAVSLWLPQQLGLLR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=456, Percent_Identity=33.7719298245614, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 49739; Mature: 49739

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLLGSFLLLMLVGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHCCHHHHHHHH
ILAGNLMNSAGVTGRIYSFAVALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIE
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEE
IKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMMANVSIGALFMAGILPGVVMT
EEEECCCCCCCHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMMITVAAFAYRKRWGSDAPFNVRELLSAGMEIVVVLMVPVAIYLMMRAGLSMNAAAGI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALLVLLALDWYFGFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSTLAKASFDTIETTASVLFIVTAASVFAWLLTASQAAQLLSDAILSITDNKWVFLILVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLMLFVGCFLDTIAAITILVPILLPIVAKFDIDPVQFGLIMTLNLMIGLLHPPLGMVLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
LSRVAKLSVERTTMAIVPWLVPLFLALILITFIPAVSLWLPQQLGLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLLLGSFLLLMLVGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHCCHHHHHHHH
ILAGNLMNSAGVTGRIYSFAVALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIE
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEE
IKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMMANVSIGALFMAGILPGVVMT
EEEECCCCCCCHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMMITVAAFAYRKRWGSDAPFNVRELLSAGMEIVVVLMVPVAIYLMMRAGLSMNAAAGI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALLVLLALDWYFGFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSTLAKASFDTIETTASVLFIVTAASVFAWLLTASQAAQLLSDAILSITDNKWVFLILVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLMLFVGCFLDTIAAITILVPILLPIVAKFDIDPVQFGLIMTLNLMIGLLHPPLGMVLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
LSRVAKLSVERTTMAIVPWLVPLFLALILITFIPAVSLWLPQQLGLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]