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The map label for this gene is exuR [H]

Identifier: 86360800

GI number: 86360800

Start: 67085

End: 67843

Strand: Direct

Name: exuR [H]

Synonym: RHE_PF00067

Alternate gene names: 86360800

Gene position: 67085-67843 (Clockwise)

Preceding gene: 86360798

Following gene: 86360801

Centisome position: 10.44

GC content: 64.43

Gene sequence:

>759_bases
ATGTTTTCGCCCGTTGAATCGCGCCGCCTCTACAGGCAGGTAGCGGATCAGATTCGTTCGATGATCGCCGGCGGCGAGCT
TGTCGTCGGTCAGAAGTTGCCGGCCGAGCGCGAGCTGGCGGAGCAATTGTCGGTCTCACGCCCGACCGTCCGCGAGGCGT
TGATCGTTCTCGAGGTCGAAGGTCTCGTCAACATCCGCATGGGCTCCGGCATCTATGTGGTGCGCCGGCAGGGCATCAGC
ATGGCGACAAGCGAAAGCGAGCCGGTGGAGGGACCCTTCGAATTGCTGCAGGCGCGCGCCATCATCGAGTGCGCCATCGC
CGAAGAGGCGGCAACCCGCGCCGGGCCGGAAGACATCGCTGTGCTCGACGAGGCGCTGAGGCGCATGAGCGGTGGCCTCG
ACGACGCGGCGACTGTGCTCGCCGCCGACCGCGCCTTCCATACAGGAATTGCCGCCATCATCGGCAATGCCACCCTGATC
CGCGTGACGGGCGAGATGTTCGACATGCGCATGACCCCTTATTTCGCGAAGCTGGCCAGCCATTTCGAGGGGCCGCCGAC
ATGGCGCAGTGCCGTCGATGAGCACCGGGCGATCCGCGATGCAATAGCCGCCGGCGATACGGCAGGCGCAAAAGCTGCGA
TGCGTGCCCATCTCACCCTGTCGCAGAAAAGATTTTCCGAGAGCTTCGGGGAGGAGTTTTCGGGAGAGGAGGAGCGCGGC
CGCGACAAGGCGGCTGCGAAAGGAGCCACCAAGACTTAA

Upstream 100 bases:

>100_bases
GCGACGCATTGACGCACAACTGCGAGGATGTTACCAATCGAATTGGTCAGGCCAGTTGACCAGCTGCGCGCTTGAGGAGA
AGCCCGCCGAGGAGGCCGGA

Downstream 100 bases:

>100_bases
ACCCGAGCTCGGGAGGAGAGAGCAATGAAGAGCAGACTGGCAATGATACTGTGCACCGCAGCCGCGATCATGGCGACGAC
GGCGGTCGCCCATGCCCAGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MFSPVESRRLYRQVADQIRSMIAGGELVVGQKLPAERELAEQLSVSRPTVREALIVLEVEGLVNIRMGSGIYVVRRQGIS
MATSESEPVEGPFELLQARAIIECAIAEEAATRAGPEDIAVLDEALRRMSGGLDDAATVLAADRAFHTGIAAIIGNATLI
RVTGEMFDMRMTPYFAKLASHFEGPPTWRSAVDEHRAIRDAIAAGDTAGAKAAMRAHLTLSQKRFSESFGEEFSGEEERG
RDKAAAKGATKT

Sequences:

>Translated_252_residues
MFSPVESRRLYRQVADQIRSMIAGGELVVGQKLPAERELAEQLSVSRPTVREALIVLEVEGLVNIRMGSGIYVVRRQGIS
MATSESEPVEGPFELLQARAIIECAIAEEAATRAGPEDIAVLDEALRRMSGGLDDAATVLAADRAFHTGIAAIIGNATLI
RVTGEMFDMRMTPYFAKLASHFEGPPTWRSAVDEHRAIRDAIAAGDTAGAKAAMRAHLTLSQKRFSESFGEEFSGEEERG
RDKAAAKGATKT
>Mature_252_residues
MFSPVESRRLYRQVADQIRSMIAGGELVVGQKLPAERELAEQLSVSRPTVREALIVLEVEGLVNIRMGSGIYVVRRQGIS
MATSESEPVEGPFELLQARAIIECAIAEEAATRAGPEDIAVLDEALRRMSGGLDDAATVLAADRAFHTGIAAIIGNATLI
RVTGEMFDMRMTPYFAKLASHFEGPPTWRSAVDEHRAIRDAIAAGDTAGAKAAMRAHLTLSQKRFSESFGEEFSGEEERG
RDKAAAKGATKT

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=238, Percent_Identity=37.3949579831933, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790780, Length=233, Percent_Identity=36.9098712446352, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1790032, Length=237, Percent_Identity=36.2869198312236, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789621, Length=225, Percent_Identity=30.6666666666667, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786303, Length=231, Percent_Identity=32.9004329004329, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789353, Length=232, Percent_Identity=26.2931034482759, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994955, Length=214, Percent_Identity=26.6355140186916, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27230; Mature: 27230

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSPVESRRLYRQVADQIRSMIAGGELVVGQKLPAERELAEQLSVSRPTVREALIVLEVE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHEEEEC
GLVNIRMGSGIYVVRRQGISMATSESEPVEGPFELLQARAIIECAIAEEAATRAGPEDIA
CEEEEEECCCEEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VLDEALRRMSGGLDDAATVLAADRAFHTGIAAIIGNATLIRVTGEMFDMRMTPYFAKLAS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCHHHHHHHH
HFEGPPTWRSAVDEHRAIRDAIAAGDTAGAKAAMRAHLTLSQKRFSESFGEEFSGEEERG
HCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
RDKAAAKGATKT
CHHHHHCCCCCC
>Mature Secondary Structure
MFSPVESRRLYRQVADQIRSMIAGGELVVGQKLPAERELAEQLSVSRPTVREALIVLEVE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHEEEEC
GLVNIRMGSGIYVVRRQGISMATSESEPVEGPFELLQARAIIECAIAEEAATRAGPEDIA
CEEEEEECCCEEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VLDEALRRMSGGLDDAATVLAADRAFHTGIAAIIGNATLIRVTGEMFDMRMTPYFAKLAS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCHHHHHHHH
HFEGPPTWRSAVDEHRAIRDAIAAGDTAGAKAAMRAHLTLSQKRFSESFGEEFSGEEERG
HCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
RDKAAAKGATKT
CHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA