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The map label for this gene is yycF [H]

Identifier: 85860919

GI number: 85860919

Start: 3090900

End: 3092108

Strand: Direct

Name: yycF [H]

Synonym: SYN_00230

Alternate gene names: 85860919

Gene position: 3090900-3092108 (Clockwise)

Preceding gene: 85860918

Following gene: 85860920

Centisome position: 97.22

GC content: 51.86

Gene sequence:

>1209_bases
ATGAAGGAAAAAATCCTGATCATTGATGATTCCCCGGACATCCGGGCATTGCTCGCCCGCTTCCTCAGGAAGGCCGGCTA
TGACATTGCGGAAGCTCACGATGGCGAGGACGGTCTGAGGCAGGTGAAAGCATGGAAACCGGATCTGATTCTCCTGGATA
TCGTCATGCCCGGCATTGACGGCTATCAGGTCTGCCGGAGCATCAAGGGCGATTCCTGCTCCAGAGACATCCCCGTCATT
TTTCTTTCTGCGCGGTCTGAGGCGGCTGACAAGATCAAAGGTCTGGCAATCGGTGGTGCGGATTACATTACCAAGCCTTT
TGACCGGGGAGAAGTGATGGCCCGCATCGAAAATCAGTTTAAGATCCGCCATCTGACCTACGAGCTGATCCTCGCCAACG
CTGAACTGACGGAAAAACAGAAACGTCTGGATGAGGATCTCCAGGCGGCTGCCGGAATCCAGCGAAGTCTTTTGCCACAG
AAAATTCCTCAGATAGAGGGATTGGATATCGCGTGGAAGTTTATGCCCTCCGAACAGATCGGCGGCGACATTTTCAACGT
GCTCCGTCTCGATGAGGACCACATCGGATTTTACATGATCGACATCAGCGGCCATGGAGTGCCTGCGGCCCTCGTGACGT
TTTCCGTATCCCAGGCACTCCAGCCCCATATGGGCTATACCATCAGGAAAATACCCGGGTCCGTGGCCTGTCCCGACTAC
GAAATCGTGCCTCCGCAGGAGGTTCTGAAGGCCTTGGATGGAGAATACCCCTGGGATCGTTTCGAAAAGTTTCTGACGAT
CATCTACCTGATCGTCAATCTCCGCGAAGGAAGTCTCGTTTACAGTAACGCCGCTCATCCACCGCCTCTTCTTCTCCATC
AAGACGGAGCATTCAAGCTGCTTGACAAAGGGGGCACCATCATCGGTCTGGATGGAATCCTGCCCTTTGAAGAGGGAGAG
GAGACGGTTCGGGAAGGAGACAAGATCCTGCTCTATACCGATGGGGTGTTTGAATTTACAAATGAAGAAGGGGAAATTTT
CGGAGAGAAACGGTTTTATGACGTTGTGAAAAGTCTGATCCAAAAGCCGATCAGCGCGATTCTGGATGAGATCGTTGCCG
CAATTCAGAATTATGTCAAGGGAGCAAACCTTCAGGATGATGTAAGTCTCCTGGGCATTGAATTCAAGAAGAGGAAAATA
AACACCTGA

Upstream 100 bases:

>100_bases
CCATTCTGAACATTGCCCGTTCCGGAAAATTCTCCAGTGACAGAGCCGTTTCCGAGTACGCTGGACTCATCTGGAATACA
GAATCCGTCAAGGAAGGGTA

Downstream 100 bases:

>100_bases
GGTGGTAAATCATGCAATTACACCAGACAAAAAATGGGGATGTCCTGATCGTAAAACCTTTGGAAAAAAGGATCGACGCC
GCTACCGCAACGGAATTTAA

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MKEKILIIDDSPDIRALLARFLRKAGYDIAEAHDGEDGLRQVKAWKPDLILLDIVMPGIDGYQVCRSIKGDSCSRDIPVI
FLSARSEAADKIKGLAIGGADYITKPFDRGEVMARIENQFKIRHLTYELILANAELTEKQKRLDEDLQAAAGIQRSLLPQ
KIPQIEGLDIAWKFMPSEQIGGDIFNVLRLDEDHIGFYMIDISGHGVPAALVTFSVSQALQPHMGYTIRKIPGSVACPDY
EIVPPQEVLKALDGEYPWDRFEKFLTIIYLIVNLREGSLVYSNAAHPPPLLLHQDGAFKLLDKGGTIIGLDGILPFEEGE
ETVREGDKILLYTDGVFEFTNEEGEIFGEKRFYDVVKSLIQKPISAILDEIVAAIQNYVKGANLQDDVSLLGIEFKKRKI
NT

Sequences:

>Translated_402_residues
MKEKILIIDDSPDIRALLARFLRKAGYDIAEAHDGEDGLRQVKAWKPDLILLDIVMPGIDGYQVCRSIKGDSCSRDIPVI
FLSARSEAADKIKGLAIGGADYITKPFDRGEVMARIENQFKIRHLTYELILANAELTEKQKRLDEDLQAAAGIQRSLLPQ
KIPQIEGLDIAWKFMPSEQIGGDIFNVLRLDEDHIGFYMIDISGHGVPAALVTFSVSQALQPHMGYTIRKIPGSVACPDY
EIVPPQEVLKALDGEYPWDRFEKFLTIIYLIVNLREGSLVYSNAAHPPPLLLHQDGAFKLLDKGGTIIGLDGILPFEEGE
ETVREGDKILLYTDGVFEFTNEEGEIFGEKRFYDVVKSLIQKPISAILDEIVAAIQNYVKGANLQDDVSLLGIEFKKRKI
NT
>Mature_402_residues
MKEKILIIDDSPDIRALLARFLRKAGYDIAEAHDGEDGLRQVKAWKPDLILLDIVMPGIDGYQVCRSIKGDSCSRDIPVI
FLSARSEAADKIKGLAIGGADYITKPFDRGEVMARIENQFKIRHLTYELILANAELTEKQKRLDEDLQAAAGIQRSLLPQ
KIPQIEGLDIAWKFMPSEQIGGDIFNVLRLDEDHIGFYMIDISGHGVPAALVTFSVSQALQPHMGYTIRKIPGSVACPDY
EIVPPQEVLKALDGEYPWDRFEKFLTIIYLIVNLREGSLVYSNAAHPPPLLLHQDGAFKLLDKGGTIIGLDGILPFEEGE
ETVREGDKILLYTDGVFEFTNEEGEIFGEKRFYDVVKSLIQKPISAILDEIVAAIQNYVKGANLQDDVSLLGIEFKKRKI
NT

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=41.8803418803419, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788394, Length=132, Percent_Identity=39.3939393939394, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789809, Length=113, Percent_Identity=39.8230088495575, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082012, Length=123, Percent_Identity=39.0243902439024, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1786911, Length=121, Percent_Identity=40.495867768595, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790860, Length=120, Percent_Identity=32.5, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1786784, Length=139, Percent_Identity=30.2158273381295, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790863, Length=114, Percent_Identity=35.0877192982456, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787229, Length=119, Percent_Identity=33.6134453781513, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787375, Length=114, Percent_Identity=30.7017543859649, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787487, Length=216, Percent_Identity=25.462962962963, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=32.5, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=124, Percent_Identity=33.0645161290323, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI2367329, Length=125, Percent_Identity=34.4, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=26.0504201680672, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789402, Length=114, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 44910; Mature: 44910

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKILIIDDSPDIRALLARFLRKAGYDIAEAHDGEDGLRQVKAWKPDLILLDIVMPGID
CCCCEEEEECCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCC
GYQVCRSIKGDSCSRDIPVIFLSARSEAADKIKGLAIGGADYITKPFDRGEVMARIENQF
HHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHCEEEECCHHHHCCCCCCHHHHHHHHHHH
KIRHLTYELILANAELTEKQKRLDEDLQAAAGIQRSLLPQKIPQIEGLDIAWKFMPSEQI
HHHEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
GGDIFNVLRLDEDHIGFYMIDISGHGVPAALVTFSVSQALQPHMGYTIRKIPGSVACPDY
CHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHCCEEEEECCCCCCCCCC
EIVPPQEVLKALDGEYPWDRFEKFLTIIYLIVNLREGSLVYSNAAHPPPLLLHQDGAFKL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCEEE
LDKGGTIIGLDGILPFEEGEETVREGDKILLYTDGVFEFTNEEGEIFGEKRFYDVVKSLI
EECCCCEEEECCCCCCCCCHHHHHCCCEEEEEECCEEEEECCCCCEECHHHHHHHHHHHH
QKPISAILDEIVAAIQNYVKGANLQDDVSLLGIEFKKRKINT
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEHHCCCCC
>Mature Secondary Structure
MKEKILIIDDSPDIRALLARFLRKAGYDIAEAHDGEDGLRQVKAWKPDLILLDIVMPGID
CCCCEEEEECCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCC
GYQVCRSIKGDSCSRDIPVIFLSARSEAADKIKGLAIGGADYITKPFDRGEVMARIENQF
HHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHCEEEECCHHHHCCCCCCHHHHHHHHHHH
KIRHLTYELILANAELTEKQKRLDEDLQAAAGIQRSLLPQKIPQIEGLDIAWKFMPSEQI
HHHEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
GGDIFNVLRLDEDHIGFYMIDISGHGVPAALVTFSVSQALQPHMGYTIRKIPGSVACPDY
CHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHCCEEEEECCCCCCCCCC
EIVPPQEVLKALDGEYPWDRFEKFLTIIYLIVNLREGSLVYSNAAHPPPLLLHQDGAFKL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCEEE
LDKGGTIIGLDGILPFEEGEETVREGDKILLYTDGVFEFTNEEGEIFGEKRFYDVVKSLI
EECCCCEEEECCCCCCCCCHHHHHCCCEEEEEECCEEEEECCCCCEECHHHHHHHHHHHH
QKPISAILDEIVAAIQNYVKGANLQDDVSLLGIEFKKRKINT
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]