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The map label for this gene is fadB1 [H]

Identifier: 85860872

GI number: 85860872

Start: 3033855

End: 3034625

Strand: Direct

Name: fadB1 [H]

Synonym: SYN_01653

Alternate gene names: 85860872

Gene position: 3033855-3034625 (Clockwise)

Preceding gene: 85860871

Following gene: 85860873

Centisome position: 95.43

GC content: 51.36

Gene sequence:

>771_bases
ATGGGATTCAACACTATTCTTTTTGAAAAGAAAGACAAAGTTGCCACAATTACACTGAATGTCCCCAATTCAAACTGGCT
TACCATACCGATGATGAAAGAGATCAACGAAGCTCTGATGGATGTCAAGAAGGATCCGACCATTCAGCTTCTCGTTTTCG
ATCATGCCGGTGATAAAGCCTTCTGTGACGGTGTCGATGTTGCCGATCACGTCCCCGAAAAAGTGGACGAGATGATCGAC
CTGTTCCACGGCATGTTCCGCAACATGGCCGCCATGGATGTGACCTCCGTATGCCTGGTCAACGGCCGTTCCCTAGGCGG
CGGTTGCGAACTCATGGCCTTCTGCGACATCGTCATCGCCTCCGAGAAGGCCAAGATCGGGCAGCCCGAAATCAACCTTG
CCGTCTTCCCGCCTGTGGCTGCGGCCTGGTTCCCCAAGATTATGGGTCTTAAAAAGGCAATGGAACTGATCCTCACCGGA
AAGATCATTTCGGCGAAAGAAGCGGAAGCCATTGGGCTGGTCAATGTCGTACTCCCGGTGGAAGGTTTCAGGGAAGCCGC
ACAGAAATTCATGGCTGATTTCACCAGCAAGAGCAGACCCGTTGCGATGTGGGCCCGTCGCGCCATCATGGCCGGCCTTA
ATTTGGATTTCCTCCAGGCCCTTAAAGCATCGGAAATTATCTACATGCAGGGTTGCATGGCGACTGAAGATGCAAATGAA
GGACTTGCCTCATTCCTGGAAAAGAGAAAACCGGTGTTCAAGGACAAATAA

Upstream 100 bases:

>100_bases
GCTGAGAGAACTGAGCGTGATATTCATGAGCTCTTTACGGATTAATCTCAGCCCTTGACTTCACAATTTCACTTTAACCT
CAAGAGAAAGGGAGATTGTT

Downstream 100 bases:

>100_bases
TCGTCCATGATTTATACTCCGAAAGAAGAGATTATAAACAGGACGGATAAATTAAGGACTTTAATGGGGAGGGCCTCACT
CGATGGGGCCTTCTTCCATT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGFNTILFEKKDKVATITLNVPNSNWLTIPMMKEINEALMDVKKDPTIQLLVFDHAGDKAFCDGVDVADHVPEKVDEMID
LFHGMFRNMAAMDVTSVCLVNGRSLGGGCELMAFCDIVIASEKAKIGQPEINLAVFPPVAAAWFPKIMGLKKAMELILTG
KIISAKEAEAIGLVNVVLPVEGFREAAQKFMADFTSKSRPVAMWARRAIMAGLNLDFLQALKASEIIYMQGCMATEDANE
GLASFLEKRKPVFKDK

Sequences:

>Translated_256_residues
MGFNTILFEKKDKVATITLNVPNSNWLTIPMMKEINEALMDVKKDPTIQLLVFDHAGDKAFCDGVDVADHVPEKVDEMID
LFHGMFRNMAAMDVTSVCLVNGRSLGGGCELMAFCDIVIASEKAKIGQPEINLAVFPPVAAAWFPKIMGLKKAMELILTG
KIISAKEAEAIGLVNVVLPVEGFREAAQKFMADFTSKSRPVAMWARRAIMAGLNLDFLQALKASEIIYMQGCMATEDANE
GLASFLEKRKPVFKDK
>Mature_255_residues
GFNTILFEKKDKVATITLNVPNSNWLTIPMMKEINEALMDVKKDPTIQLLVFDHAGDKAFCDGVDVADHVPEKVDEMIDL
FHGMFRNMAAMDVTSVCLVNGRSLGGGCELMAFCDIVIASEKAKIGQPEINLAVFPPVAAAWFPKIMGLKKAMELILTGK
IISAKEAEAIGLVNVVLPVEGFREAAQKFMADFTSKSRPVAMWARRAIMAGLNLDFLQALKASEIIYMQGCMATEDANEG
LASFLEKRKPVFKDK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=260, Percent_Identity=33.4615384615385, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=26.8, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4502327, Length=238, Percent_Identity=30.2521008403361, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI260274832, Length=260, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI45643119, Length=260, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI260275230, Length=260, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI37594469, Length=176, Percent_Identity=30.6818181818182, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI37594471, Length=176, Percent_Identity=30.6818181818182, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI25453481, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI51538573, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4757966, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI51538581, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI116235487, Length=189, Percent_Identity=31.2169312169312, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4757968, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI49355787, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI221136756, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI221136753, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI221307494, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI68989263, Length=231, Percent_Identity=28.1385281385281, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788597, Length=267, Percent_Identity=32.5842696629214, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=28.740157480315, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=25.0922509225092, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=28.8461538461538, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788682, Length=210, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790281, Length=205, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=25.9541984732824, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=33.6032388663968, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=32.0158102766798, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=233, Percent_Identity=29.1845493562232, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=253, Percent_Identity=29.6442687747036, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=253, Percent_Identity=28.0632411067194, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=180, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=180, Percent_Identity=28.8888888888889, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=247, Percent_Identity=24.2914979757085, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=209, Percent_Identity=25.8373205741627, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=205, Percent_Identity=26.3414634146341, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129971, Length=249, Percent_Identity=34.136546184739, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653477, Length=249, Percent_Identity=34.136546184739, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653139, Length=253, Percent_Identity=31.6205533596838, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=24.8031496062992, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357171, Length=185, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24654903, Length=184, Percent_Identity=25.5434782608696, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28135; Mature: 28004

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFNTILFEKKDKVATITLNVPNSNWLTIPMMKEINEALMDVKKDPTIQLLVFDHAGDKA
CCCCCEEEECCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCC
FCDGVDVADHVPEKVDEMIDLFHGMFRNMAAMDVTSVCLVNGRSLGGGCELMAFCDIVIA
CCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHC
SEKAKIGQPEINLAVFPPVAAAWFPKIMGLKKAMELILTGKIISAKEAEAIGLVNVVLPV
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHEEEEEEECC
EGFREAAQKFMADFTSKSRPVAMWARRAIMAGLNLDFLQALKASEIIYMQGCMATEDANE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCHH
GLASFLEKRKPVFKDK
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GFNTILFEKKDKVATITLNVPNSNWLTIPMMKEINEALMDVKKDPTIQLLVFDHAGDKA
CCCCEEEECCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCC
FCDGVDVADHVPEKVDEMIDLFHGMFRNMAAMDVTSVCLVNGRSLGGGCELMAFCDIVIA
CCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHC
SEKAKIGQPEINLAVFPPVAAAWFPKIMGLKKAMELILTGKIISAKEAEAIGLVNVVLPV
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHEEEEEEECC
EGFREAAQKFMADFTSKSRPVAMWARRAIMAGLNLDFLQALKASEIIYMQGCMATEDANE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCHH
GLASFLEKRKPVFKDK
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]