Click here to switch to the map view.

The map label for this gene is pepQ [H]

Identifier: 85860873

GI number: 85860873

Start: 3034632

End: 3035807

Strand: Direct

Name: pepQ [H]

Synonym: SYN_01652

Alternate gene names: 85860873

Gene position: 3034632-3035807 (Clockwise)

Preceding gene: 85860872

Following gene: 85860875

Centisome position: 95.45

GC content: 52.47

Gene sequence:

>1176_bases
ATGATTTATACTCCGAAAGAAGAGATTATAAACAGGACGGATAAATTAAGGACTTTAATGGGGAGGGCCTCACTCGATGG
GGCCTTCTTCCATTATAAGATCGATTATTTTTACCTCTCAGGAACCATGCAGGACGCCTTTCTCTATGTTCCGCTCAACG
GTGAGCCCAAGCTCTTCGTCCGGCGGGAGATGCGTCGGGCACGGCGGGAATCGCCCCTTTCCGACCTGATCCCCCTTCGA
TCCCTTGAGACCGTCAAGGCCCATATCGGCAACCCGCGGAGAGTTGGTTTTCAGCTTGATGTGATGCCATACAATTTTGT
CATGCGTTTTCAAAAGCTTTTGGGGGATGTTGAACTGGTGGATGTTTCACCGCTGATCATTGACCTCCGAAAGATCAAGA
GCCCCTTTGAAGTCGGGTTGATGGATAAGGCGGCGGCCATTGCCGGGAAGGTTTACGAAAAAATCCCCGAAGTGCTCCGG
GAAGGGATGACTGAGATTGAGCTCGGCGGGATACTGGAAGCCTATGCCAAGACCCTCGGGCATGAAGGACTGCTGCGCAC
ACGATCCCTGATTTTCGAGGCCTATACCTGGCATATTCTGAGTGGGAAGACGGGAAGCATCGTCAGTCAGATGAATTCCC
CCCTGGGTGGCCTGGGCATGTCGCCGGCCTTTCCCGTCGGGGCCAGCCGCAAGAAAATCCGGAGGGGAGAGCCGATCATG
ATCGATTTCGGCATCTGTTATCACGGGTATCAGGTGGATGAGACCCGCATGTTTGCCATCGGCCATATGCCGGAACGTTT
TGCCGATGCCTATGAAGCCTGCCGGGAGATCCATTACCGGGTGCTGGATAAAGCTCTGGAAGGCGTTTCCTGCTCAGAAC
TTTTTCAGTATTCCGTGGAGCTTGCCGACAGGATGGGATATGGCGATTATTATCTCGGTTACACTCCGCACAAAGTCAAT
TTTCTGGCTCACGGAATCGGTATAGAGATTTCTGAACCCCCTTTCATTGCTGCAAAGATGGATTACCCCCTGTTAGAAGG
GATGACGCTGGCGATTGAACCCAAGATGGTCTTTCCGCGACAGGGCGCCTGCGGTATCGAGAATACGGTTTTGATCGAGA
AAGACCGGTATCGCGTGCTCACCCGGATGGATGAAAAGATTATCGTGGTCGATTGA

Upstream 100 bases:

>100_bases
TATCTACATGCAGGGTTGCATGGCGACTGAAGATGCAAATGAAGGACTTGCCTCATTCCTGGAAAAGAGAAAACCGGTGT
TCAAGGACAAATAATCGTCC

Downstream 100 bases:

>100_bases
GATCACTCCTGTAAAGGCGCCCTTGCCGGATATTCCTTCGCTCCAGCTCCCGGTCAATGGCGTTGAGGACGCTCATCTTG
TTTGAAGCCCATGCCGGGGC

Product: xaa-pro aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MIYTPKEEIINRTDKLRTLMGRASLDGAFFHYKIDYFYLSGTMQDAFLYVPLNGEPKLFVRREMRRARRESPLSDLIPLR
SLETVKAHIGNPRRVGFQLDVMPYNFVMRFQKLLGDVELVDVSPLIIDLRKIKSPFEVGLMDKAAAIAGKVYEKIPEVLR
EGMTEIELGGILEAYAKTLGHEGLLRTRSLIFEAYTWHILSGKTGSIVSQMNSPLGGLGMSPAFPVGASRKKIRRGEPIM
IDFGICYHGYQVDETRMFAIGHMPERFADAYEACREIHYRVLDKALEGVSCSELFQYSVELADRMGYGDYYLGYTPHKVN
FLAHGIGIEISEPPFIAAKMDYPLLEGMTLAIEPKMVFPRQGACGIENTVLIEKDRYRVLTRMDEKIIVVD

Sequences:

>Translated_391_residues
MIYTPKEEIINRTDKLRTLMGRASLDGAFFHYKIDYFYLSGTMQDAFLYVPLNGEPKLFVRREMRRARRESPLSDLIPLR
SLETVKAHIGNPRRVGFQLDVMPYNFVMRFQKLLGDVELVDVSPLIIDLRKIKSPFEVGLMDKAAAIAGKVYEKIPEVLR
EGMTEIELGGILEAYAKTLGHEGLLRTRSLIFEAYTWHILSGKTGSIVSQMNSPLGGLGMSPAFPVGASRKKIRRGEPIM
IDFGICYHGYQVDETRMFAIGHMPERFADAYEACREIHYRVLDKALEGVSCSELFQYSVELADRMGYGDYYLGYTPHKVN
FLAHGIGIEISEPPFIAAKMDYPLLEGMTLAIEPKMVFPRQGACGIENTVLIEKDRYRVLTRMDEKIIVVD
>Mature_391_residues
MIYTPKEEIINRTDKLRTLMGRASLDGAFFHYKIDYFYLSGTMQDAFLYVPLNGEPKLFVRREMRRARRESPLSDLIPLR
SLETVKAHIGNPRRVGFQLDVMPYNFVMRFQKLLGDVELVDVSPLIIDLRKIKSPFEVGLMDKAAAIAGKVYEKIPEVLR
EGMTEIELGGILEAYAKTLGHEGLLRTRSLIFEAYTWHILSGKTGSIVSQMNSPLGGLGMSPAFPVGASRKKIRRGEPIM
IDFGICYHGYQVDETRMFAIGHMPERFADAYEACREIHYRVLDKALEGVSCSELFQYSVELADRMGYGDYYLGYTPHKVN
FLAHGIGIEISEPPFIAAKMDYPLLEGMTLAIEPKMVFPRQGACGIENTVLIEKDRYRVLTRMDEKIIVVD

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=304, Percent_Identity=26.6447368421053, Blast_Score=95, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44431; Mature: 44431

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTPKEEIINRTDKLRTLMGRASLDGAFFHYKIDYFYLSGTMQDAFLYVPLNGEPKLFV
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCEEEEEEECCCCCHHH
RREMRRARRESPLSDLIPLRSLETVKAHIGNPRRVGFQLDVMPYNFVMRFQKLLGDVELV
HHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCEEECEEEEECCHHHHHHHHHHHCCEEEE
DVSPLIIDLRKIKSPFEVGLMDKAAAIAGKVYEKIPEVLREGMTEIELGGILEAYAKTLG
ECCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
HEGLLRTRSLIFEAYTWHILSGKTGSIVSQMNSPLGGLGMSPAFPVGASRKKIRRGEPIM
CCHHHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEE
IDFGICYHGYQVDETRMFAIGHMPERFADAYEACREIHYRVLDKALEGVSCSELFQYSVE
EEEEEEECCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LADRMGYGDYYLGYTPHKVNFLAHGIGIEISEPPFIAAKMDYPLLEGMTLAIEPKMVFPR
HHHHCCCCCEEECCCCCEEEEEEECCCEEECCCCEEEEECCCHHHCCEEEEECCCEECCC
QGACGIENTVLIEKDRYRVLTRMDEKIIVVD
CCCCCCCCEEEEECHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MIYTPKEEIINRTDKLRTLMGRASLDGAFFHYKIDYFYLSGTMQDAFLYVPLNGEPKLFV
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCEEEEEEECCCCCHHH
RREMRRARRESPLSDLIPLRSLETVKAHIGNPRRVGFQLDVMPYNFVMRFQKLLGDVELV
HHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCEEECEEEEECCHHHHHHHHHHHCCEEEE
DVSPLIIDLRKIKSPFEVGLMDKAAAIAGKVYEKIPEVLREGMTEIELGGILEAYAKTLG
ECCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
HEGLLRTRSLIFEAYTWHILSGKTGSIVSQMNSPLGGLGMSPAFPVGASRKKIRRGEPIM
CCHHHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEE
IDFGICYHGYQVDETRMFAIGHMPERFADAYEACREIHYRVLDKALEGVSCSELFQYSVE
EEEEEEECCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LADRMGYGDYYLGYTPHKVNFLAHGIGIEISEPPFIAAKMDYPLLEGMTLAIEPKMVFPR
HHHHCCCCCEEECCCCCEEEEEEECCCEEECCCCEEEEECCCHHHCCEEEEECCCEECCC
QGACGIENTVLIEKDRYRVLTRMDEKIIVVD
CCCCCCCCEEEEECHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]