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The map label for this gene is menB [H]

Identifier: 85860871

GI number: 85860871

Start: 3032541

End: 3033689

Strand: Direct

Name: menB [H]

Synonym: SYN_01654

Alternate gene names: 85860871

Gene position: 3032541-3033689 (Clockwise)

Preceding gene: 85860870

Following gene: 85860872

Centisome position: 95.38

GC content: 52.92

Gene sequence:

>1149_bases
ATGAGTTTAGATTGGATGCCAAGAGAACACGGGTTAAAGAATCACAGCCGACATACTGAACAGTGGTGGGGCACGGAAGC
ACCCTGCACCGTATACGAGAAGAGACCCTTGAAGGACCCCAAGGGTAATGTAGTTCCCGGCCTTTACAGCGCCTGGATCA
GACTGAACAACCCGGGCCAGTACAATTCTTATACAACCGAGATGGTTAAAGGTGTTATCGCCGGTTTTGAGAATTCCTCC
ACCGACCGCGAAGTCGTTGCCGTCGTCTTCACCGGAACAGGTCCTAATGCCTTCTGTACAGGCGGCAACACGAAGGAATA
TTCCGAATATTACAGCATGAGACCGGAAGAATACGGCTCCTACATGGAACTGTTCAACAATATGGTGGACTCCATCCTGA
TGTGCAAAAAACCGGTCATCTGCCGCGTTAACGGCATGAGAGTGGCTGGTGGTCAGGAAATCGGCACTGCCACAGACATT
ACCGTTTCTTCCGACTTGGCCATTTTCGGTCAGGCCGGACCCCGCCACGGCTCAGCCCCCGTCGGCGGCGCCTCCGATTT
TCTCCCCTGGTTCCTCAGCATTGAAGACGCCATGTGGAACTGCGTAAGCTGTGAAATGTGGTCTGCCTACAAGATGAAAG
CCAAAAACCTCATCTCCAAGGCCCTTCCCGTGCTGAAGGACGACAAAGGCAACTGGGTAAGAAACCCCCAGGTCTATACC
GACACCTATGTAAAAGACGGCGAGATCGTTTACGGCGAACCCAAGACCGGCGAAGAAGCCAAACAGGCACGTGCCTGGGT
CAACGAGAAACTGAAGAACAACGATTACGATTTCTCCCTCATCGATGCCGAAGTCGACCGGATTGTCTGGGTTTTCGCAA
ATCTGTTCCCCGGCTGCCTGATGAAATCCATCGACGGCATCCGCCAGAAGAAGAAATTCTGGTGGGATCAGATCAAGAAC
GACCACCGTTACTGGCTCGGCACCAACATGATGGGCGAAGCCTTCCTGGGCTTCGGCGCATTCAACACGAAGAAGATCAC
CGGAAAAGACACGATCGACTTCATAAAGAATCGTCAGCTGATCGCGGAAGGCGCCCTGGTCGACGAAGCTTTCATGGAGC
AGGTCCTCGGAAAACCGCTGGCAAAATAA

Upstream 100 bases:

>100_bases
ATGATGAAGTTCACAAAGCCGGTTCTCCGGAAAAGAGAATTGTTTTGAAGCCTGATTTTTAGAAAATCACCAAATAAAAT
AACGTATAAGGGGGATTAGT

Downstream 100 bases:

>100_bases
TTTTCAGATTCAAATTAAAGGGGGGGACTCCCCCCCTTTTTTATTTCAAACAGCTCCACAAAAAGGCTGAGAGAACTGAG
CGTGATATTCATGAGCTCTT

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSLDWMPREHGLKNHSRHTEQWWGTEAPCTVYEKRPLKDPKGNVVPGLYSAWIRLNNPGQYNSYTTEMVKGVIAGFENSS
TDREVVAVVFTGTGPNAFCTGGNTKEYSEYYSMRPEEYGSYMELFNNMVDSILMCKKPVICRVNGMRVAGGQEIGTATDI
TVSSDLAIFGQAGPRHGSAPVGGASDFLPWFLSIEDAMWNCVSCEMWSAYKMKAKNLISKALPVLKDDKGNWVRNPQVYT
DTYVKDGEIVYGEPKTGEEAKQARAWVNEKLKNNDYDFSLIDAEVDRIVWVFANLFPGCLMKSIDGIRQKKKFWWDQIKN
DHRYWLGTNMMGEAFLGFGAFNTKKITGKDTIDFIKNRQLIAEGALVDEAFMEQVLGKPLAK

Sequences:

>Translated_382_residues
MSLDWMPREHGLKNHSRHTEQWWGTEAPCTVYEKRPLKDPKGNVVPGLYSAWIRLNNPGQYNSYTTEMVKGVIAGFENSS
TDREVVAVVFTGTGPNAFCTGGNTKEYSEYYSMRPEEYGSYMELFNNMVDSILMCKKPVICRVNGMRVAGGQEIGTATDI
TVSSDLAIFGQAGPRHGSAPVGGASDFLPWFLSIEDAMWNCVSCEMWSAYKMKAKNLISKALPVLKDDKGNWVRNPQVYT
DTYVKDGEIVYGEPKTGEEAKQARAWVNEKLKNNDYDFSLIDAEVDRIVWVFANLFPGCLMKSIDGIRQKKKFWWDQIKN
DHRYWLGTNMMGEAFLGFGAFNTKKITGKDTIDFIKNRQLIAEGALVDEAFMEQVLGKPLAK
>Mature_381_residues
SLDWMPREHGLKNHSRHTEQWWGTEAPCTVYEKRPLKDPKGNVVPGLYSAWIRLNNPGQYNSYTTEMVKGVIAGFENSST
DREVVAVVFTGTGPNAFCTGGNTKEYSEYYSMRPEEYGSYMELFNNMVDSILMCKKPVICRVNGMRVAGGQEIGTATDIT
VSSDLAIFGQAGPRHGSAPVGGASDFLPWFLSIEDAMWNCVSCEMWSAYKMKAKNLISKALPVLKDDKGNWVRNPQVYTD
TYVKDGEIVYGEPKTGEEAKQARAWVNEKLKNNDYDFSLIDAEVDRIVWVFANLFPGCLMKSIDGIRQKKKFWWDQIKND
HRYWLGTNMMGEAFLGFGAFNTKKITGKDTIDFIKNRQLIAEGALVDEAFMEQVLGKPLAK

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Escherichia coli, GI1788597, Length=186, Percent_Identity=26.3440860215054, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=176, Percent_Identity=30.6818181818182, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=175, Percent_Identity=29.1428571428571, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI20129971, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653477, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 43102; Mature: 42971

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50270 NGF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDWMPREHGLKNHSRHTEQWWGTEAPCTVYEKRPLKDPKGNVVPGLYSAWIRLNNPGQ
CCCCCCCHHCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCC
YNSYTTEMVKGVIAGFENSSTDREVVAVVFTGTGPNAFCTGGNTKEYSEYYSMRPEEYGS
CCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHHHHHCCCHHHHH
YMELFNNMVDSILMCKKPVICRVNGMRVAGGQEIGTATDITVSSDLAIFGQAGPRHGSAP
HHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCEEEEEECCCEEEEECCCCCCCCCC
VGGASDFLPWFLSIEDAMWNCVSCEMWSAYKMKAKNLISKALPVLKDDKGNWVRNPQVYT
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEE
DTYVKDGEIVYGEPKTGEEAKQARAWVNEKLKNNDYDFSLIDAEVDRIVWVFANLFPGCL
CCEEECCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
MKSIDGIRQKKKFWWDQIKNDHRYWLGTNMMGEAFLGFGAFNTKKITGKDTIDFIKNRQL
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCCEECCCHHHHHHHCCHH
IAEGALVDEAFMEQVLGKPLAK
HHHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLDWMPREHGLKNHSRHTEQWWGTEAPCTVYEKRPLKDPKGNVVPGLYSAWIRLNNPGQ
CCCCCCHHCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCC
YNSYTTEMVKGVIAGFENSSTDREVVAVVFTGTGPNAFCTGGNTKEYSEYYSMRPEEYGS
CCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHHHHHCCCHHHHH
YMELFNNMVDSILMCKKPVICRVNGMRVAGGQEIGTATDITVSSDLAIFGQAGPRHGSAP
HHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCEEEEEECCCEEEEECCCCCCCCCC
VGGASDFLPWFLSIEDAMWNCVSCEMWSAYKMKAKNLISKALPVLKDDKGNWVRNPQVYT
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEE
DTYVKDGEIVYGEPKTGEEAKQARAWVNEKLKNNDYDFSLIDAEVDRIVWVFANLFPGCL
CCEEECCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
MKSIDGIRQKKKFWWDQIKNDHRYWLGTNMMGEAFLGFGAFNTKKITGKDTIDFIKNRQL
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCCCCEECCCHHHHHHHCCHH
IAEGALVDEAFMEQVLGKPLAK
HHHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]