Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 85860830

GI number: 85860830

Start: 2997248

End: 2998228

Strand: Direct

Name: fabH [H]

Synonym: SYN_01698

Alternate gene names: 85860830

Gene position: 2997248-2998228 (Clockwise)

Preceding gene: 85860829

Following gene: 85860831

Centisome position: 94.27

GC content: 51.99

Gene sequence:

>981_bases
ATGTTATATCTACATGGCTTAGGACATTTTCACCCTGAAAATGTCATCAGCAATCAATTCCTGGAAGAACTCGATATCGG
CACGAACGAAGAGTGGATTATCGAGCGGGTGGGTATTCTTTCTCGGCGAACAGTCCTGCCTCTGGATTACATCCGTTCGA
CCAGAAACCAGGATCAGCGGGCAGCTTTTGAGGCTGCTGAATACAACAACGCACAGACAGGCTCTTTTGCGGCCAGAATG
GCCCTTGAGCGGGCAGGCATTTCCCCTGAAGACATCGGCATGGTCATTTCGGGAAGTTCCGCCCAGGACATGCTGACACC
AGCGGAAGCATCGACGGTCGCCGGAGAGTTGAACATTGACGTTCCCTGTTTCGACATAAATTCCGCATGCAGCACCTTCG
GTATGCATATCAATGTCCTTGGCATGATGAAACCGGAAGCTCTTCCTCCCTTTGTGCTGCTCGTCAACCCCGAAAATATG
ACACGAAACGTGAATTACGCGGATCGCAGCGTAGCCGTCCTCTGGGGTGACGGAAGTGCGGCCGCGGTGGTTTCCACACG
GGAACGTTCCCGTGCCGTTTTTCTCTCCAGCCACTGCGATTCGAAACCTACCGCATGGGAAAAGGTCATGATTCCCCGGA
TGGGCTATTTTCAGCAGGATGGGCATGCGGTTCAGGGGTTTGCCATCCGCAAGACAACAGAATCGATTCGTGCCCTGCAA
TCTTTGTATCCGGTCAACCGTTTTGTCGGCCATCAGGCAAATCTCGGCATGCTTCGCACAGCTTGTGAGCGTACAGGAAT
CACGGAAGATCAGCATTGGCATAATGTTGAACTTTTTGGCAATACAGGCTGCTCAAGCGCCCCTGCCGTATTGAGTCAGC
ATTGGGATGACTTCACTCCCGGCGATCATATTGCGGTTTGCGTTGTGGGAGGCGGTCTGACTTGGGTGCACACCCTTTTA
AAAATTGAGGATATTAAATGA

Upstream 100 bases:

>100_bases
ATGAGATTTCCAAGCTCGTTCGTGATGTTCATATAATTGACATTTACGAGGGAACCCGTGAAGTCCAGAACATGATCATC
GGGCGGGAACTTGTATAATT

Downstream 100 bases:

>100_bases
CTTACGAAGAATTTTGTAAGCAAGGAAGCTTCTCTCTCGAAGATTTGCTTGCCTTTGCATACGGCAATCTTGTAGATGAT
CGTCCCGATGGCTTTGACGC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLYLHGLGHFHPENVISNQFLEELDIGTNEEWIIERVGILSRRTVLPLDYIRSTRNQDQRAAFEAAEYNNAQTGSFAARM
ALERAGISPEDIGMVISGSSAQDMLTPAEASTVAGELNIDVPCFDINSACSTFGMHINVLGMMKPEALPPFVLLVNPENM
TRNVNYADRSVAVLWGDGSAAAVVSTRERSRAVFLSSHCDSKPTAWEKVMIPRMGYFQQDGHAVQGFAIRKTTESIRALQ
SLYPVNRFVGHQANLGMLRTACERTGITEDQHWHNVELFGNTGCSSAPAVLSQHWDDFTPGDHIAVCVVGGGLTWVHTLL
KIEDIK

Sequences:

>Translated_326_residues
MLYLHGLGHFHPENVISNQFLEELDIGTNEEWIIERVGILSRRTVLPLDYIRSTRNQDQRAAFEAAEYNNAQTGSFAARM
ALERAGISPEDIGMVISGSSAQDMLTPAEASTVAGELNIDVPCFDINSACSTFGMHINVLGMMKPEALPPFVLLVNPENM
TRNVNYADRSVAVLWGDGSAAAVVSTRERSRAVFLSSHCDSKPTAWEKVMIPRMGYFQQDGHAVQGFAIRKTTESIRALQ
SLYPVNRFVGHQANLGMLRTACERTGITEDQHWHNVELFGNTGCSSAPAVLSQHWDDFTPGDHIAVCVVGGGLTWVHTLL
KIEDIK
>Mature_326_residues
MLYLHGLGHFHPENVISNQFLEELDIGTNEEWIIERVGILSRRTVLPLDYIRSTRNQDQRAAFEAAEYNNAQTGSFAARM
ALERAGISPEDIGMVISGSSAQDMLTPAEASTVAGELNIDVPCFDINSACSTFGMHINVLGMMKPEALPPFVLLVNPENM
TRNVNYADRSVAVLWGDGSAAAVVSTRERSRAVFLSSHCDSKPTAWEKVMIPRMGYFQQDGHAVQGFAIRKTTESIRALQ
SLYPVNRFVGHQANLGMLRTACERTGITEDQHWHNVELFGNTGCSSAPAVLSQHWDDFTPGDHIAVCVVGGGLTWVHTLL
KIEDIK

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=332, Percent_Identity=24.6987951807229, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35915; Mature: 35915

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLHGLGHFHPENVISNQFLEELDIGTNEEWIIERVGILSRRTVLPLDYIRSTRNQDQR
CEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHH
AAFEAAEYNNAQTGSFAARMALERAGISPEDIGMVISGSSAQDMLTPAEASTVAGELNID
HHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHCCEEEECCCCHHHCCCCCHHHEECEEEEC
VPCFDINSACSTFGMHINVLGMMKPEALPPFVLLVNPENMTRNVNYADRSVAVLWGDGSA
EEEEECCHHHHHHCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCE
AAVVSTRERSRAVFLSSHCDSKPTAWEKVMIPRMGYFQQDGHAVQGFAIRKTTESIRALQ
EEEEEECCCCCEEEEECCCCCCCCCHHHEECCCCCCCCCCCCEEEEEEEEHHHHHHHHHH
SLYPVNRFVGHQANLGMLRTACERTGITEDQHWHNVELFGNTGCSSAPAVLSQHWDDFTP
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCC
GDHIAVCVVGGGLTWVHTLLKIEDIK
CCCEEEEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLYLHGLGHFHPENVISNQFLEELDIGTNEEWIIERVGILSRRTVLPLDYIRSTRNQDQR
CEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHH
AAFEAAEYNNAQTGSFAARMALERAGISPEDIGMVISGSSAQDMLTPAEASTVAGELNID
HHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHCCEEEECCCCHHHCCCCCHHHEECEEEEC
VPCFDINSACSTFGMHINVLGMMKPEALPPFVLLVNPENMTRNVNYADRSVAVLWGDGSA
EEEEECCHHHHHHCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCE
AAVVSTRERSRAVFLSSHCDSKPTAWEKVMIPRMGYFQQDGHAVQGFAIRKTTESIRALQ
EEEEEECCCCCEEEEECCCCCCCCCHHHEECCCCCCCCCCCCEEEEEEEEHHHHHHHHHH
SLYPVNRFVGHQANLGMLRTACERTGITEDQHWHNVELFGNTGCSSAPAVLSQHWDDFTP
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCC
GDHIAVCVVGGGLTWVHTLLKIEDIK
CCCEEEEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA