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The map label for this gene is fabA [H]

Identifier: 85860831

GI number: 85860831

Start: 2998225

End: 2998815

Strand: Direct

Name: fabA [H]

Synonym: SYN_01697

Alternate gene names: 85860831

Gene position: 2998225-2998815 (Clockwise)

Preceding gene: 85860830

Following gene: 85860832

Centisome position: 94.3

GC content: 51.1

Gene sequence:

>591_bases
ATGACTTACGAAGAATTTTGTAAGCAAGGAAGCTTCTCTCTCGAAGATTTGCTTGCCTTTGCATACGGCAATCTTGTAGA
TGATCGTCCCGATGGCTTTGACGCACGTCTTCCTGCCCCTCCTTTTCTCATGCTGGATCGGATTCTGACGATCACAAGTG
AAGGCCGGCAGGGACGCATCGTAGCGGAGCAGGATATTCGTCTTGACGCCTGGTATTTCCAGTGCCATATGCCCGGCGAC
CCGGTCCAGCCGGGTTGCCTCTGTGTCGATGCCATCTGGCAGCTGCTCGGATTTTATTGCGTCTGGCGGGGTGCATTGGG
TGCCGGAAGAGCGCTGGGATGCAAAAATGTTTCCTTCAACGGTCAGATTCGACCCTACAACCGTTGCGTTCGTTATGAAG
TGGATATTCGTCGTTTTTCCCATTTGAAGGATTCCGGAGCCAGCATTGTGATCGGCGATGCGAAGGTCTTTGTGGATAAT
GAATTGATCACGGAAATTACCCAGGCCCAGACCGGTGTTTTCAGTGGCATTGTTTATCCGGATTATCCAAAACACTCCCG
CAATTCAGTGGGAGGAATGATCAGGAGTTGA

Upstream 100 bases:

>100_bases
AGCATTGGGATGACTTCACTCCCGGCGATCATATTGCGGTTTGCGTTGTGGGAGGCGGTCTGACTTGGGTGCACACCCTT
TTAAAAATTGAGGATATTAA

Downstream 100 bases:

>100_bases
ACATGAGTCAAGACAAACCAGTTGCCATCATCACCGGAGGAGGTACGGGAATCGGTGCGGCCTGTTCCAGAATTCTTTCC
CGGGATGGTTTCCGTGTGGG

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTYEEFCKQGSFSLEDLLAFAYGNLVDDRPDGFDARLPAPPFLMLDRILTITSEGRQGRIVAEQDIRLDAWYFQCHMPGD
PVQPGCLCVDAIWQLLGFYCVWRGALGAGRALGCKNVSFNGQIRPYNRCVRYEVDIRRFSHLKDSGASIVIGDAKVFVDN
ELITEITQAQTGVFSGIVYPDYPKHSRNSVGGMIRS

Sequences:

>Translated_196_residues
MTYEEFCKQGSFSLEDLLAFAYGNLVDDRPDGFDARLPAPPFLMLDRILTITSEGRQGRIVAEQDIRLDAWYFQCHMPGD
PVQPGCLCVDAIWQLLGFYCVWRGALGAGRALGCKNVSFNGQIRPYNRCVRYEVDIRRFSHLKDSGASIVIGDAKVFVDN
ELITEITQAQTGVFSGIVYPDYPKHSRNSVGGMIRS
>Mature_195_residues
TYEEFCKQGSFSLEDLLAFAYGNLVDDRPDGFDARLPAPPFLMLDRILTITSEGRQGRIVAEQDIRLDAWYFQCHMPGDP
VQPGCLCVDAIWQLLGFYCVWRGALGAGRALGCKNVSFNGQIRPYNRCVRYEVDIRRFSHLKDSGASIVIGDAKVFVDNE
LITEITQAQTGVFSGIVYPDYPKHSRNSVGGMIRS

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=171, Percent_Identity=40.3508771929825, Blast_Score=130, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 21953; Mature: 21822

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYEEFCKQGSFSLEDLLAFAYGNLVDDRPDGFDARLPAPPFLMLDRILTITSEGRQGRI
CCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCE
VAEQDIRLDAWYFQCHMPGDPVQPGCLCVDAIWQLLGFYCVWRGALGAGRALGCKNVSFN
EECCCCEEEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GQIRPYNRCVRYEVDIRRFSHLKDSGASIVIGDAKVFVDNELITEITQAQTGVFSGIVYP
CEECCCCCEEEEEEHHHHHHHHCCCCCEEEEECEEEEECHHHHHHHHHHHHHHHCCCCCC
DYPKHSRNSVGGMIRS
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TYEEFCKQGSFSLEDLLAFAYGNLVDDRPDGFDARLPAPPFLMLDRILTITSEGRQGRI
CHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCE
VAEQDIRLDAWYFQCHMPGDPVQPGCLCVDAIWQLLGFYCVWRGALGAGRALGCKNVSFN
EECCCCEEEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GQIRPYNRCVRYEVDIRRFSHLKDSGASIVIGDAKVFVDNELITEITQAQTGVFSGIVYP
CEECCCCCEEEEEEHHHHHHHHCCCCCEEEEECEEEEECHHHHHHHHHHHHHHHCCCCCC
DYPKHSRNSVGGMIRS
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA