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The map label for this gene is katA [H]

Identifier: 85860726

GI number: 85860726

Start: 2907006

End: 2908544

Strand: Direct

Name: katA [H]

Synonym: SYN_02396

Alternate gene names: 85860726

Gene position: 2907006-2908544 (Clockwise)

Preceding gene: 85860725

Following gene: 85860727

Centisome position: 91.44

GC content: 58.74

Gene sequence:

>1539_bases
TTGTTAATAGTTCAGCCAACCTTTCCCGGCTTTCTGCCGGGACAACGCAAAATAAGGGAGGAGAAAGCAATGAGCAAGGA
AAAGAAATTAACGACCCGGGCCGGCGCCCCCGTCGTCGACAACAACAACATCATGACTGCCGGGCCACGAGGGCCACAGC
TTCTGCAGGATGTCTGGTACCTGGAGAAAATGGCCCACTTTGACCGGGAGGTGATTCCCGAACGGCGGATGCATGCCAAG
GGCTCCGGCGCCTACGGCACCTTCACCATCACCCAGGACATCACCAGGTACACGAAGGCAAAGATCTTTTCCGAGATTGG
GAAAAAAACAGAGATGTTCGCGCGCTTTTCCACGGTGGCCGGAGAACGCGGCGCTGCCGACGCCGAGCGGGACATTCGCG
GTTTTGCGCTTAAATTCTACACCGAGGAGGGTAACTGGGATCTGGTGGGCAACAACACGCCCGTCTTCTTCCTCCGCGAC
CCGCTCAAATTTCCGGACCTCAACCATGTCGTCCATCGCGATCCGCGCACCAATCTGCGTAACGCCAACAGCATGTGGGA
CTTCTGGACGTCCCTGCCTGAGGCCCTGCATCAGGTGACCGTGGTAATGAGTGACCGCGGGATCCCGGCAAGCTATCGTC
ACATGCACGGCTTCGGCAGCCACACCTTCAGCTTCATCAGCCCCAAAAACGAGCGCTACTGGGTCAAGTTCCACTTCCGC
ACCCAGCAGGGGATCAAAAATCTCACCGACGCGGAGGCTGAGGCTGCAATCGGCCAATGCAGGGAAAGCCATCAGCGGGA
TCTCTACTACAGCATCGAGAACGGCGATTTTCCGCGCTGGACCATGTACGTCCAGATCATGACTGAAGAGCAGGCCCTGA
ACCATCCCTACAACCCCTTCGACCTGACCAAGGTCTGGTATCACAGCGATTATCCCCTCATCGAGGTCGGAGTCATGGAG
CTGAACAGGAACCCGGAAAACTACTTCGCCGAGGTCGAACAGTCCGCCTTCAATCCGGCCCACGTCGTGCCCGGCATTGG
TTTTTCACCCGACAAGATGCTCCAGGGTCGCCTCTTCTCCTACGGCGACGCCCAGCGCTACCGGCTCGGCGTAAACCATC
TCTCGATCCCCGTAAACGCACCCCGCTGTCCCTTCCACAGTTATCACCGCGACGGCCAGATGCGGGTAGACGGCAACTAC
GGTTCGACCATCGGCTACGAACCCAACAGCTACGGCGAGTGGCAGGAGCAGATCGACTTCGCCGAACCGCCCCTTAAGCT
CTATGGCGACGCCAAGAACTGGAACTTCCGCGAGGACGATGACGACTACTACACTCAGCCCGGCAAACTCTTCCGCCTGA
TGAGTCCGGAGCAGCAGCAGGCCCTTTTCGGGAACACCGCCCGCGCCATCGCAGAAGCTGCAAAAGAGATCAAGATGCGC
CACATCGGCAACTGCATGAAGGCCGACCCGGCCTACGGCAAAGGAGTGGCCGACGCCCTGGGCCTTCCTCCGTATCCCAT
GAGCGATATCTGCGCGTAA

Upstream 100 bases:

>100_bases
TACCTGTCTCAATCAAACTCACAAAAAGAATTTCTGAAATAAACATTGTTTTTGCCATCTAAATAAGATAATTTCTTATT
TAGAAAATCGTCAGCGGCCA

Downstream 100 bases:

>100_bases
GCCTTGTTTGTCTCTGCTCACACCGACCTGAGCAGGCGGCGGCTCCAAAGAAGATCGGGCAGCCGCCTGCTTTTTTCGTC
AGACCGATCCCTGTCGGCAG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MLIVQPTFPGFLPGQRKIREEKAMSKEKKLTTRAGAPVVDNNNIMTAGPRGPQLLQDVWYLEKMAHFDREVIPERRMHAK
GSGAYGTFTITQDITRYTKAKIFSEIGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRD
PLKFPDLNHVVHRDPRTNLRNANSMWDFWTSLPEALHQVTVVMSDRGIPASYRHMHGFGSHTFSFISPKNERYWVKFHFR
TQQGIKNLTDAEAEAAIGQCRESHQRDLYYSIENGDFPRWTMYVQIMTEEQALNHPYNPFDLTKVWYHSDYPLIEVGVME
LNRNPENYFAEVEQSAFNPAHVVPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHLSIPVNAPRCPFHSYHRDGQMRVDGNY
GSTIGYEPNSYGEWQEQIDFAEPPLKLYGDAKNWNFREDDDDYYTQPGKLFRLMSPEQQQALFGNTARAIAEAAKEIKMR
HIGNCMKADPAYGKGVADALGLPPYPMSDICA

Sequences:

>Translated_512_residues
MLIVQPTFPGFLPGQRKIREEKAMSKEKKLTTRAGAPVVDNNNIMTAGPRGPQLLQDVWYLEKMAHFDREVIPERRMHAK
GSGAYGTFTITQDITRYTKAKIFSEIGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRD
PLKFPDLNHVVHRDPRTNLRNANSMWDFWTSLPEALHQVTVVMSDRGIPASYRHMHGFGSHTFSFISPKNERYWVKFHFR
TQQGIKNLTDAEAEAAIGQCRESHQRDLYYSIENGDFPRWTMYVQIMTEEQALNHPYNPFDLTKVWYHSDYPLIEVGVME
LNRNPENYFAEVEQSAFNPAHVVPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHLSIPVNAPRCPFHSYHRDGQMRVDGNY
GSTIGYEPNSYGEWQEQIDFAEPPLKLYGDAKNWNFREDDDDYYTQPGKLFRLMSPEQQQALFGNTARAIAEAAKEIKMR
HIGNCMKADPAYGKGVADALGLPPYPMSDICA
>Mature_512_residues
MLIVQPTFPGFLPGQRKIREEKAMSKEKKLTTRAGAPVVDNNNIMTAGPRGPQLLQDVWYLEKMAHFDREVIPERRMHAK
GSGAYGTFTITQDITRYTKAKIFSEIGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRD
PLKFPDLNHVVHRDPRTNLRNANSMWDFWTSLPEALHQVTVVMSDRGIPASYRHMHGFGSHTFSFISPKNERYWVKFHFR
TQQGIKNLTDAEAEAAIGQCRESHQRDLYYSIENGDFPRWTMYVQIMTEEQALNHPYNPFDLTKVWYHSDYPLIEVGVME
LNRNPENYFAEVEQSAFNPAHVVPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHLSIPVNAPRCPFHSYHRDGQMRVDGNY
GSTIGYEPNSYGEWQEQIDFAEPPLKLYGDAKNWNFREDDDDYYTQPGKLFRLMSPEQQQALFGNTARAIAEAAKEIKMR
HIGNCMKADPAYGKGVADALGLPPYPMSDICA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=484, Percent_Identity=50.6198347107438, Blast_Score=494, Evalue=1e-139,
Organism=Escherichia coli, GI48994891, Length=523, Percent_Identity=39.961759082218, Blast_Score=359, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71998444, Length=473, Percent_Identity=50.3171247357294, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI25147792, Length=477, Percent_Identity=48.4276729559748, Blast_Score=471, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI25151141, Length=502, Percent_Identity=47.0119521912351, Blast_Score=471, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6320462, Length=504, Percent_Identity=43.8492063492063, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321525, Length=517, Percent_Identity=36.3636363636364, Blast_Score=300, Evalue=3e-82,
Organism=Drosophila melanogaster, GI17981717, Length=476, Percent_Identity=48.109243697479, Blast_Score=456, Evalue=1e-128,
Organism=Drosophila melanogaster, GI19920968, Length=477, Percent_Identity=43.8155136268344, Blast_Score=421, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 58658; Mature: 58658

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVQPTFPGFLPGQRKIREEKAMSKEKKLTTRAGAPVVDNNNIMTAGPRGPQLLQDVWY
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECCCCCHHHHHHHHH
LEKMAHFDREVIPERRMHAKGSGAYGTFTITQDITRYTKAKIFSEIGKKTEMFARFSTVA
HHHHHHHHHHHCCHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
GERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHVVHRDPRTNLR
CCCCCCCHHHCCCEEEEEEEEECCCEEEECCCCCEEEEECCCCCCCCCHHHCCCCCCCCC
NANSMWDFWTSLPEALHQVTVVMSDRGIPASYRHMHGFGSHTFSFISPKNERYWVKFHFR
CCCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHCCCCCCEEEEECCCCCEEEEEEEEE
TQQGIKNLTDAEAEAAIGQCRESHQRDLYYSIENGDFPRWTMYVQIMTEEQALNHPYNPF
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEEHHHHHCCCCCCC
DLTKVWYHSDYPLIEVGVMELNRNPENYFAEVEQSAFNPAHVVPGIGFSPDKMLQGRLFS
EEEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHC
YGDAQRYRLGVNHLSIPVNAPRCPFHSYHRDGQMRVDGNYGSTIGYEPNSYGEWQEQIDF
CCCCHHEEECCCEEEECCCCCCCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHCCC
AEPPLKLYGDAKNWNFREDDDDYYTQPGKLFRLMSPEQQQALFGNTARAIAEAAKEIKMR
CCCCCEEEECCCCCCCCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
HIGNCMKADPAYGKGVADALGLPPYPMSDICA
HHCCHHCCCCCCCCCHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MLIVQPTFPGFLPGQRKIREEKAMSKEKKLTTRAGAPVVDNNNIMTAGPRGPQLLQDVWY
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECCCCCHHHHHHHHH
LEKMAHFDREVIPERRMHAKGSGAYGTFTITQDITRYTKAKIFSEIGKKTEMFARFSTVA
HHHHHHHHHHHCCHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
GERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHVVHRDPRTNLR
CCCCCCCHHHCCCEEEEEEEEECCCEEEECCCCCEEEEECCCCCCCCCHHHCCCCCCCCC
NANSMWDFWTSLPEALHQVTVVMSDRGIPASYRHMHGFGSHTFSFISPKNERYWVKFHFR
CCCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHCCCCCCEEEEECCCCCEEEEEEEEE
TQQGIKNLTDAEAEAAIGQCRESHQRDLYYSIENGDFPRWTMYVQIMTEEQALNHPYNPF
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEEHHHHHCCCCCCC
DLTKVWYHSDYPLIEVGVMELNRNPENYFAEVEQSAFNPAHVVPGIGFSPDKMLQGRLFS
EEEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHC
YGDAQRYRLGVNHLSIPVNAPRCPFHSYHRDGQMRVDGNYGSTIGYEPNSYGEWQEQIDF
CCCCHHEEECCCEEEECCCCCCCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHCCC
AEPPLKLYGDAKNWNFREDDDDYYTQPGKLFRLMSPEQQQALFGNTARAIAEAAKEIKMR
CCCCCEEEECCCCCCCCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
HIGNCMKADPAYGKGVADALGLPPYPMSDICA
HHCCHHCCCCCCCCCHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA