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The map label for this gene is uppP

Identifier: 85860727

GI number: 85860727

Start: 2908829

End: 2909860

Strand: Direct

Name: uppP

Synonym: SYN_02394

Alternate gene names: 85860727

Gene position: 2908829-2909860 (Clockwise)

Preceding gene: 85860726

Following gene: 85860732

Centisome position: 91.49

GC content: 59.21

Gene sequence:

>1032_bases
TTGAAGAAACACCACCTCCGACATGCTCTGCTTGTTCTTTCAGCCGCAATCCTTCTCGCGGTTTCATGCTCCTTTTCCGC
TGCCTCCGCCTCCGCGTCCCCGCCCGCATCCGAGAAAAAAATCGCCGTATGGGAGGCCGCGATCCTGGGAGTTGTCGAAG
GCATCACGGAATATCTGCCCATCTCTTCCACAGGACACCTGATCCTTGCCAGCCACGCCCTGGGTATGACGCAGTTCAGT
GAAACGCGCGGCCCCCTGGGCACTCTCATGGTTAAAAACGACGCCATGGACTCTTACAACATTGTCATTCAGCTCGGGGC
GATCCTTGCCGTCCTGGGACTTTATCGCAAGCGGGTGAAACAGATGCTGAAAGGATTGAGCGGGGCTTTGGCTGTCCTTG
TATCCCGCAGGTCGGTCACGGCACTGGGGGATTCTGAGCGGCAGGGGCTCAAGCTCCTTGGACTGCTGCTGCTCGCCTTC
CTGCCGGCCGCCGTGTTCGGGAAACTCTTTCATGAAGTCATCGAGACGTATCTTTTTGGCCCGCTGCCCGTGGTGTACGC
CCTGGTGGCCGGCGGGGTCCTGATGATCGGAGTGGAGTATTTCTTCTGGCTGAAGGATCGCAACCGGCTGCGCATATCCG
ATGTCAATTCGATGTTCTACCGGCAGGCCCTGTTCATCGGGATGATGCAGGTGGTGTCGATGTGGCCGGGAACGAGCCGG
AGCATGATCACCATGATCGCCGGGCTGATCGTCGGCCTCGACATGATCGCGGCCGCCGAGTTCAGTTTTCTCCTGGCCCT
GCCGACCCTCGGCGCGGCGACGCTGTATTCCGGATACAAAAACTGGCATGCCCTTGATGATTCCGCCGGAATGCTGGCCC
TGGCAGTGGGACTGGCCGTGAGCTGGCTGACCGCCGTGATCGCCGTAAAAGCCCTGGTCAGATGGCTGACCCATCACGGC
CTCATCCCCTTCGGCGTATATAGAATCCTGCTGGCAGGGGTTCTGCTCATCTACTTCTGGCAGTGGAGATGA

Upstream 100 bases:

>100_bases
CCTTAAGCTCTCTGTCCCGGAAAGGATTTACAAATTTACTCAAAGCCGTTTCCCTCATTCCCCGGAATGACAGGATACCG
CTTTGTCAGGAGATCTTTTA

Downstream 100 bases:

>100_bases
CGGAGTTGAGTTCTACATCGAAACTATGCCTTGGACGACGGTGTCATCGTTTCCTGAATGATCGCCTTATCTATCCCGCA
CCGCCCCGGCCGCCCTGCTT

Product: bacitracin resistance protein

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKKHHLRHALLVLSAAILLAVSCSFSAASASASPPASEKKIAVWEAAILGVVEGITEYLPISSTGHLILASHALGMTQFS
ETRGPLGTLMVKNDAMDSYNIVIQLGAILAVLGLYRKRVKQMLKGLSGALAVLVSRRSVTALGDSERQGLKLLGLLLLAF
LPAAVFGKLFHEVIETYLFGPLPVVYALVAGGVLMIGVEYFFWLKDRNRLRISDVNSMFYRQALFIGMMQVVSMWPGTSR
SMITMIAGLIVGLDMIAAAEFSFLLALPTLGAATLYSGYKNWHALDDSAGMLALAVGLAVSWLTAVIAVKALVRWLTHHG
LIPFGVYRILLAGVLLIYFWQWR

Sequences:

>Translated_343_residues
MKKHHLRHALLVLSAAILLAVSCSFSAASASASPPASEKKIAVWEAAILGVVEGITEYLPISSTGHLILASHALGMTQFS
ETRGPLGTLMVKNDAMDSYNIVIQLGAILAVLGLYRKRVKQMLKGLSGALAVLVSRRSVTALGDSERQGLKLLGLLLLAF
LPAAVFGKLFHEVIETYLFGPLPVVYALVAGGVLMIGVEYFFWLKDRNRLRISDVNSMFYRQALFIGMMQVVSMWPGTSR
SMITMIAGLIVGLDMIAAAEFSFLLALPTLGAATLYSGYKNWHALDDSAGMLALAVGLAVSWLTAVIAVKALVRWLTHHG
LIPFGVYRILLAGVLLIYFWQWR
>Mature_343_residues
MKKHHLRHALLVLSAAILLAVSCSFSAASASASPPASEKKIAVWEAAILGVVEGITEYLPISSTGHLILASHALGMTQFS
ETRGPLGTLMVKNDAMDSYNIVIQLGAILAVLGLYRKRVKQMLKGLSGALAVLVSRRSVTALGDSERQGLKLLGLLLLAF
LPAAVFGKLFHEVIETYLFGPLPVVYALVAGGVLMIGVEYFFWLKDRNRLRISDVNSMFYRQALFIGMMQVVSMWPGTSR
SMITMIAGLIVGLDMIAAAEFSFLLALPTLGAATLYSGYKNWHALDDSAGMLALAVGLAVSWLTAVIAVKALVRWLTHHG
LIPFGVYRILLAGVLLIYFWQWR

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=295, Percent_Identity=38.3050847457627, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_SYNAS (Q2LXE8)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_462930.1
- STRING:   Q2LXE8
- GeneID:   3882491
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_02394
- NMPDR:   fig|56780.10.peg.2857
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- PhylomeDB:   Q2LXE8
- BioCyc:   SACI56780:SYN_02394-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 37216; Mature: 37216

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17b24780)-; HASH(0x17dd9014)-; HASH(0x17b736d0)-; HASH(0x1806bd38)-; HASH(0x182cb464)-; HASH(0x18689518)-; HASH(0x189439f0)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHHLRHALLVLSAAILLAVSCSFSAASASASPPASEKKIAVWEAAILGVVEGITEYLP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
ISSTGHLILASHALGMTQFSETRGPLGTLMVKNDAMDSYNIVIQLGAILAVLGLYRKRVK
CCCCCCEEEEHHHHCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
QMLKGLSGALAVLVSRRSVTALGDSERQGLKLLGLLLLAFLPAAVFGKLFHEVIETYLFG
HHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLPVVYALVAGGVLMIGVEYFFWLKDRNRLRISDVNSMFYRQALFIGMMQVVSMWPGTSR
HHHHHHHHHHCCHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SMITMIAGLIVGLDMIAAAEFSFLLALPTLGAATLYSGYKNWHALDDSAGMLALAVGLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
SWLTAVIAVKALVRWLTHHGLIPFGVYRILLAGVLLIYFWQWR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MKKHHLRHALLVLSAAILLAVSCSFSAASASASPPASEKKIAVWEAAILGVVEGITEYLP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
ISSTGHLILASHALGMTQFSETRGPLGTLMVKNDAMDSYNIVIQLGAILAVLGLYRKRVK
CCCCCCEEEEHHHHCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
QMLKGLSGALAVLVSRRSVTALGDSERQGLKLLGLLLLAFLPAAVFGKLFHEVIETYLFG
HHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLPVVYALVAGGVLMIGVEYFFWLKDRNRLRISDVNSMFYRQALFIGMMQVVSMWPGTSR
HHHHHHHHHHCCHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SMITMIAGLIVGLDMIAAAEFSFLLALPTLGAATLYSGYKNWHALDDSAGMLALAVGLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
SWLTAVIAVKALVRWLTHHGLIPFGVYRILLAGVLLIYFWQWR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA