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The map label for this gene is rpe [H]

Identifier: 85860497

GI number: 85860497

Start: 2678264

End: 2678950

Strand: Direct

Name: rpe [H]

Synonym: SYN_01763

Alternate gene names: 85860497

Gene position: 2678264-2678950 (Clockwise)

Preceding gene: 85860494

Following gene: 85860498

Centisome position: 84.24

GC content: 58.81

Gene sequence:

>687_bases
ATGAAAAAAATTGCCCCTTCAATCCTTTCCGCCGATTTCAGCCGTCTGGGCGACGAGATCGCCGCCGTGGAGGCTGCCGG
AGCGGACTGGATCCATATCGATGTAATGGACGGCCACTTCGTCCCCAATCTGACGATCGGACCGCCGGTCGTCAAGTCTC
TGCGCAAGGTCACAAGGCTGCCCTTTGATGTCCATCTGATGATCGACAACCCGGATTCTTATCTTGACGCATTCATCGAC
GCCGGCTGCGATATCCTGACCGTTCACGCGGAAGCGGCAGTTCACCTGCACCGCACCATCTCCTATATCAGGGAACGGGG
CGTTTCGGCCGGTGTTTCAGTCAATCCGGCAACCCCTTTGAGTCTGCTGGAAGACATCCTGCCCGATCTGGATCTGCTTC
TCATCATGACCGTGAACCCCGGTTTCGGCGGACAGCAGTTTATCCCCACGATGCTGCCGAAAATCCGCAAGGCCAAGGCC
ATGATTTCGGCGGTTTCCCCCCGGATCGTCATCGAAGTGGACGGGGGGATCAACCTGGATAACATTTCAACCGTCGCCCA
GGCCGGAGCGGATGTCCTCGTTGCGGGCTCCGCCGTTTTCGCGAGCGGCGATTATGGCCTTACCCTGCCGGCCATGCGCG
CCCTGCTGGAAAACAGCCCGGAACCCTGTACATTCCCGACAGCCTGA

Upstream 100 bases:

>100_bases
TGACGGCCCGGCGGAGATGTTGTAACGGTTTCCGGGTGATGTCATCTTTAATCTGAAATTGGAATGACCTGACATAATTT
AAGGATTGCGGTTTTAACTT

Downstream 100 bases:

>100_bases
ACTTTCTTTTCCCGCCATGCACATTATCATCGACGGCTACAACCTGATCAGGCAATCCGATTTCCTCCGCCATTTTGAAC
GCCGAAGCCTGGAAGCCGGG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKKIAPSILSADFSRLGDEIAAVEAAGADWIHIDVMDGHFVPNLTIGPPVVKSLRKVTRLPFDVHLMIDNPDSYLDAFID
AGCDILTVHAEAAVHLHRTISYIRERGVSAGVSVNPATPLSLLEDILPDLDLLLIMTVNPGFGGQQFIPTMLPKIRKAKA
MISAVSPRIVIEVDGGINLDNISTVAQAGADVLVAGSAVFASGDYGLTLPAMRALLENSPEPCTFPTA

Sequences:

>Translated_228_residues
MKKIAPSILSADFSRLGDEIAAVEAAGADWIHIDVMDGHFVPNLTIGPPVVKSLRKVTRLPFDVHLMIDNPDSYLDAFID
AGCDILTVHAEAAVHLHRTISYIRERGVSAGVSVNPATPLSLLEDILPDLDLLLIMTVNPGFGGQQFIPTMLPKIRKAKA
MISAVSPRIVIEVDGGINLDNISTVAQAGADVLVAGSAVFASGDYGLTLPAMRALLENSPEPCTFPTA
>Mature_228_residues
MKKIAPSILSADFSRLGDEIAAVEAAGADWIHIDVMDGHFVPNLTIGPPVVKSLRKVTRLPFDVHLMIDNPDSYLDAFID
AGCDILTVHAEAAVHLHRTISYIRERGVSAGVSVNPATPLSLLEDILPDLDLLLIMTVNPGFGGQQFIPTMLPKIRKAKA
MISAVSPRIVIEVDGGINLDNISTVAQAGADVLVAGSAVFASGDYGLTLPAMRALLENSPEPCTFPTA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=204, Percent_Identity=42.6470588235294, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI219879828, Length=204, Percent_Identity=40.6862745098039, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI24307923, Length=159, Percent_Identity=32.0754716981132, Blast_Score=94, Evalue=7e-20,
Organism=Escherichia coli, GI1789788, Length=214, Percent_Identity=52.3364485981308, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=38.0710659898477, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1790754, Length=212, Percent_Identity=33.0188679245283, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17552948, Length=225, Percent_Identity=42.6666666666667, Blast_Score=183, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6322341, Length=214, Percent_Identity=43.4579439252336, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=41.0377358490566, Blast_Score=173, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24201; Mature: 24201

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAPSILSADFSRLGDEIAAVEAAGADWIHIDVMDGHFVPNLTIGPPVVKSLRKVTRL
CCCCHHHHHHHHHHHHCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCC
PFDVHLMIDNPDSYLDAFIDAGCDILTVHAEAAVHLHRTISYIRERGVSAGVSVNPATPL
CCEEEEEECCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
SLLEDILPDLDLLLIMTVNPGFGGQQFIPTMLPKIRKAKAMISAVSPRIVIEVDGGINLD
HHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
NISTVAQAGADVLVAGSAVFASGDYGLTLPAMRALLENSPEPCTFPTA
HHHHHHHCCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKKIAPSILSADFSRLGDEIAAVEAAGADWIHIDVMDGHFVPNLTIGPPVVKSLRKVTRL
CCCCHHHHHHHHHHHHCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCC
PFDVHLMIDNPDSYLDAFIDAGCDILTVHAEAAVHLHRTISYIRERGVSAGVSVNPATPL
CCEEEEEECCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
SLLEDILPDLDLLLIMTVNPGFGGQQFIPTMLPKIRKAKAMISAVSPRIVIEVDGGINLD
HHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
NISTVAQAGADVLVAGSAVFASGDYGLTLPAMRALLENSPEPCTFPTA
HHHHHHHCCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]