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The map label for this gene is ytfL [C]

Identifier: 85860285

GI number: 85860285

Start: 2463686

End: 2464984

Strand: Direct

Name: ytfL [C]

Synonym: SYN_01208

Alternate gene names: 85860285

Gene position: 2463686-2464984 (Clockwise)

Preceding gene: 85860282

Following gene: 85860294

Centisome position: 77.49

GC content: 51.81

Gene sequence:

>1299_bases
ATGAACACAATCTTGTTTGAAATTTCGATCATCGTTTTCCTGATCATTCTTAATGGTTTACTTGCTTTATCGGAACTTGC
TCTTGTTTCCGCCAGCAGGGTCCGGTTGGAAAGACTGGCAAAGGAAGGTGACTCCAAGGCACTCACCGCGCTGGAACTCG
CTGATACGCCGGACAGTTTTTTATCCACGATACAAATCGGCATTACGTTTGTCGGCATTCTGGCCGGCGCATTCGGCGGC
GCAACCCTTGCGGGGCCGCTCACCGAATATTTTGCTGTCTTCCCCATGCTTGCCCCGTACGCTCCAACAATCAGCATCGC
AGTCGTCGTCGTCTGCATCACCTATTTATCAATCGTTATCGGCGAACTGGTTCCGAAGCGGCTTGCACTCAGCAACCCGG
AAAAGCTTGCCCGCCTGGTTGCCGTTCCGATCAAACGCCTTTCCCGGCTGGCACATCCCCTGGTTCTCTTGCTGAGCGCT
TCAACCAATCTGACGCTGCGTATCTTTCACGTCCAGCCTTCCACCGAACCGGTTGTCACGGAAGAGGAGATAAGGTTGTT
GATTGACAAGGGTACGCAGGCGGGAACCTTTCAGGAGTTCGAGCAGGATACGATCGAGCGTGTGTTTCGTCTGGCCGACC
GCAGAGTGGCTTACCTGATGACCCCAAAATCTGAGATTGTCTGGCTTGACCTGGATGAAAGCCAGGAGGTGGCACAACGG
AAGATCGCGGAGCATAAATATTCTTTCTACCCTCTCGTCCACGATACGCTTGACAATGTTGTGGGAGTGATTCGTGCGAA
GGAACTTCTTGCCCTGATCATGGAGGGGAAGCCTTTTAATCTGAAAAGCGTCTGCCGTAAACCCCTTTACGTTTCCGAAA
CGACACCTGCAGTCAAGGTACTTGAATTATTCAAAAAATCAGGAATGCACATCGCTTTTGTCGTGGATGAGTACGGTGCG
ATTCTTGGACTCGTCACATTCGACGATATTCTGCATTCCGTCTTCGAAGACATCGAAGAGGGAGGCAATGGTGAAAAGGA
AATCGTGGAAAGGGAAGACGGTTCGTGGCTCATATCGGGAAGTCTGCCCCTGGATGAGTTCATGGATTACATGGAAATCG
GCGAACCGGATGAAGACGAGTTGACCGGAATGAATACCGTGGGCGGTTTTGTCATGACGATGCTCGGCACCGTTCCTGCT
GAGGGACAGCATTTCATCTGGCGCGGACTGAGATGCGAAGTCGTCGACATGGACGGCAGGCGGGTCGACAAGATTATCGT
TTCCCGATTAGAAGGCTGA

Upstream 100 bases:

>100_bases
GTATTTGAAACGACCCTGAACGATTAAAAAACATCATGAGCTTTGGACAACATTTTCAAATTCGGAAAGGAAGCAAAACA
TTACCTTCTGGTAACCCTTC

Downstream 100 bases:

>100_bases
CATAAGCAAAAGGCGTTAATCCCCCCTCAGCAGATCTGATGCGTTCCGCAGGAAAGAATCTGGTAGCCGCGGCTTTTGTT
TCGAAAAACGGTTGTGCCTT

Product: magnesium and cobalt efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MNTILFEISIIVFLIILNGLLALSELALVSASRVRLERLAKEGDSKALTALELADTPDSFLSTIQIGITFVGILAGAFGG
ATLAGPLTEYFAVFPMLAPYAPTISIAVVVVCITYLSIVIGELVPKRLALSNPEKLARLVAVPIKRLSRLAHPLVLLLSA
STNLTLRIFHVQPSTEPVVTEEEIRLLIDKGTQAGTFQEFEQDTIERVFRLADRRVAYLMTPKSEIVWLDLDESQEVAQR
KIAEHKYSFYPLVHDTLDNVVGVIRAKELLALIMEGKPFNLKSVCRKPLYVSETTPAVKVLELFKKSGMHIAFVVDEYGA
ILGLVTFDDILHSVFEDIEEGGNGEKEIVEREDGSWLISGSLPLDEFMDYMEIGEPDEDELTGMNTVGGFVMTMLGTVPA
EGQHFIWRGLRCEVVDMDGRRVDKIIVSRLEG

Sequences:

>Translated_432_residues
MNTILFEISIIVFLIILNGLLALSELALVSASRVRLERLAKEGDSKALTALELADTPDSFLSTIQIGITFVGILAGAFGG
ATLAGPLTEYFAVFPMLAPYAPTISIAVVVVCITYLSIVIGELVPKRLALSNPEKLARLVAVPIKRLSRLAHPLVLLLSA
STNLTLRIFHVQPSTEPVVTEEEIRLLIDKGTQAGTFQEFEQDTIERVFRLADRRVAYLMTPKSEIVWLDLDESQEVAQR
KIAEHKYSFYPLVHDTLDNVVGVIRAKELLALIMEGKPFNLKSVCRKPLYVSETTPAVKVLELFKKSGMHIAFVVDEYGA
ILGLVTFDDILHSVFEDIEEGGNGEKEIVEREDGSWLISGSLPLDEFMDYMEIGEPDEDELTGMNTVGGFVMTMLGTVPA
EGQHFIWRGLRCEVVDMDGRRVDKIIVSRLEG
>Mature_432_residues
MNTILFEISIIVFLIILNGLLALSELALVSASRVRLERLAKEGDSKALTALELADTPDSFLSTIQIGITFVGILAGAFGG
ATLAGPLTEYFAVFPMLAPYAPTISIAVVVVCITYLSIVIGELVPKRLALSNPEKLARLVAVPIKRLSRLAHPLVLLLSA
STNLTLRIFHVQPSTEPVVTEEEIRLLIDKGTQAGTFQEFEQDTIERVFRLADRRVAYLMTPKSEIVWLDLDESQEVAQR
KIAEHKYSFYPLVHDTLDNVVGVIRAKELLALIMEGKPFNLKSVCRKPLYVSETTPAVKVLELFKKSGMHIAFVVDEYGA
ILGLVTFDDILHSVFEDIEEGGNGEKEIVEREDGSWLISGSLPLDEFMDYMEIGEPDEDELTGMNTVGGFVMTMLGTVPA
EGQHFIWRGLRCEVVDMDGRRVDKIIVSRLEG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=372, Percent_Identity=28.494623655914, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1790664, Length=431, Percent_Identity=29.6983758700696, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI145693175, Length=388, Percent_Identity=28.0927835051546, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87082033, Length=362, Percent_Identity=27.0718232044199, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786879, Length=259, Percent_Identity=27.7992277992278, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788119, Length=233, Percent_Identity=28.3261802575107, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47777; Mature: 47777

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTILFEISIIVFLIILNGLLALSELALVSASRVRLERLAKEGDSKALTALELADTPDSF
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHH
LSTIQIGITFVGILAGAFGGATLAGPLTEYFAVFPMLAPYAPTISIAVVVVCITYLSIVI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GELVPKRLALSNPEKLARLVAVPIKRLSRLAHPLVLLLSASTNLTLRIFHVQPSTEPVVT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCCCCC
EEEIRLLIDKGTQAGTFQEFEQDTIERVFRLADRRVAYLMTPKSEIVWLDLDESQEVAQR
HHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCHHHHHHH
KIAEHKYSFYPLVHDTLDNVVGVIRAKELLALIMEGKPFNLKSVCRKPLYVSETTPAVKV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEECCCCHHHHH
LELFKKSGMHIAFVVDEYGAILGLVTFDDILHSVFEDIEEGGNGEKEIVEREDGSWLISG
HHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEC
SLPLDEFMDYMEIGEPDEDELTGMNTVGGFVMTMLGTVPAEGQHFIWRGLRCEVVDMDGR
CCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCC
RVDKIIVSRLEG
HHHHHHHHHCCC
>Mature Secondary Structure
MNTILFEISIIVFLIILNGLLALSELALVSASRVRLERLAKEGDSKALTALELADTPDSF
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHH
LSTIQIGITFVGILAGAFGGATLAGPLTEYFAVFPMLAPYAPTISIAVVVVCITYLSIVI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GELVPKRLALSNPEKLARLVAVPIKRLSRLAHPLVLLLSASTNLTLRIFHVQPSTEPVVT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCCCCC
EEEIRLLIDKGTQAGTFQEFEQDTIERVFRLADRRVAYLMTPKSEIVWLDLDESQEVAQR
HHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCHHHHHHH
KIAEHKYSFYPLVHDTLDNVVGVIRAKELLALIMEGKPFNLKSVCRKPLYVSETTPAVKV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEECCCCHHHHH
LELFKKSGMHIAFVVDEYGAILGLVTFDDILHSVFEDIEEGGNGEKEIVEREDGSWLISG
HHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEC
SLPLDEFMDYMEIGEPDEDELTGMNTVGGFVMTMLGTVPAEGQHFIWRGLRCEVVDMDGR
CCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCC
RVDKIIVSRLEG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]