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The map label for this gene is sucD [H]

Identifier: 85860261

GI number: 85860261

Start: 2447516

End: 2448391

Strand: Direct

Name: sucD [H]

Synonym: SYN_02502

Alternate gene names: 85860261

Gene position: 2447516-2448391 (Clockwise)

Preceding gene: 85860260

Following gene: 85860262

Centisome position: 76.98

GC content: 58.45

Gene sequence:

>876_bases
ATGAGCATTCTCATCAATGAGAATACGCGCGTGGCAGTGCAGGGGATTACAGGAACCGAAGGCGCTTTTCACGCGCGCCG
GATGATCGAATACGGGACTAAGGTCGTTGCCGGCGTCACACCGGGAAAAGGCGGACTTGTCCATGACGGCGTGCCGGTTT
TTGATTCAATGCGGGAGGCGGCACAGGAGACGGCCCCCGACGTCTCGGTGATTTTTGTGCCTGCCCCTTACGCCGCCGAT
GCAGTCATGGAGGCTACGGAGGCGGGGATAAAGCTGGTGGTCTGCCCTGCCGAAGGAATCCCCGTGCTTGATACGGTTCT
TGCCCGCCGCTATCTTGAAGAAAGAAAGGTGATGCTTATCGGCCCCAATACACCGGGCATTATTTCACCGGGCAAGTGTA
AGGTCGGCCTGATGGCCGGATATATTCACCGTCAGGGATCCGTGGGGGTCGTTTCCAGAAGCGGGACGCTGACCTACGAA
GCCGTTCACCAGTTGAGCCGGAAGGGAATCGGGCAGTCGACCTGTCTCGGCATTGGGGGTGATCCTGTTGTCGGACTTTC
TTTTGTCGATATTCTTCAACTTTACGAGGAAGATCCGGGGACCAAGGCCGTCGTCCTCATCGGCGAAATTGGAGGCAGTA
TGGAGGAAAAGGCGGCGGAATTCTTCAGAACGACGATGACGAAACCCCTGATCGCCTACATCGCCGGCGTGACGGCCCCC
CCGGAACGGCGCATGGGCCACGCGGGGGCCATCATTTCCAGGAACCGCGGAGGGGCTCAGGAAAAGATCCGGGCCTTGGA
GGATGCCGGGGTCATTGTGGTAAGAAATCCCGCGGAAATCGGCGATATCGTGGAAAGCGCACTCCATCTACGGTGA

Upstream 100 bases:

>100_bases
AGGGACTGAAGATTCTATCCTCCTCAGGGCTCAATTTTATCCAGGTAACCGACCTGAGGGAAGCCGTACTGCGGATCGGA
GAAGAGGTCGCGAGGGCGGG

Downstream 100 bases:

>100_bases
GGCCCCGGGCTGTCTCCACAGCCGTTGACAATATCTCTTTTCAATCTTTTATCCCCGTGTTAAAAATGAATTGTTGCATA
CCCTTTATTCAAGGAGGACT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSILINENTRVAVQGITGTEGAFHARRMIEYGTKVVAGVTPGKGGLVHDGVPVFDSMREAAQETAPDVSVIFVPAPYAAD
AVMEATEAGIKLVVCPAEGIPVLDTVLARRYLEERKVMLIGPNTPGIISPGKCKVGLMAGYIHRQGSVGVVSRSGTLTYE
AVHQLSRKGIGQSTCLGIGGDPVVGLSFVDILQLYEEDPGTKAVVLIGEIGGSMEEKAAEFFRTTMTKPLIAYIAGVTAP
PERRMGHAGAIISRNRGGAQEKIRALEDAGVIVVRNPAEIGDIVESALHLR

Sequences:

>Translated_291_residues
MSILINENTRVAVQGITGTEGAFHARRMIEYGTKVVAGVTPGKGGLVHDGVPVFDSMREAAQETAPDVSVIFVPAPYAAD
AVMEATEAGIKLVVCPAEGIPVLDTVLARRYLEERKVMLIGPNTPGIISPGKCKVGLMAGYIHRQGSVGVVSRSGTLTYE
AVHQLSRKGIGQSTCLGIGGDPVVGLSFVDILQLYEEDPGTKAVVLIGEIGGSMEEKAAEFFRTTMTKPLIAYIAGVTAP
PERRMGHAGAIISRNRGGAQEKIRALEDAGVIVVRNPAEIGDIVESALHLR
>Mature_290_residues
SILINENTRVAVQGITGTEGAFHARRMIEYGTKVVAGVTPGKGGLVHDGVPVFDSMREAAQETAPDVSVIFVPAPYAADA
VMEATEAGIKLVVCPAEGIPVLDTVLARRYLEERKVMLIGPNTPGIISPGKCKVGLMAGYIHRQGSVGVVSRSGTLTYEA
VHQLSRKGIGQSTCLGIGGDPVVGLSFVDILQLYEEDPGTKAVVLIGEIGGSMEEKAAEFFRTTMTKPLIAYIAGVTAPP
ERRMGHAGAIISRNRGGAQEKIRALEDAGVIVVRNPAEIGDIVESALHLR

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=52.3809523809524, Blast_Score=275, Evalue=3e-74,
Organism=Homo sapiens, GI38569423, Length=251, Percent_Identity=35.4581673306773, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI38569421, Length=251, Percent_Identity=35.4581673306773, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1786949, Length=288, Percent_Identity=56.5972222222222, Blast_Score=344, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=53.0821917808219, Blast_Score=297, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=52.0547945205479, Blast_Score=293, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI17557344, Length=249, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17551266, Length=249, Percent_Identity=32.9317269076305, Blast_Score=104, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6324716, Length=290, Percent_Identity=43.7931034482759, Blast_Score=232, Evalue=7e-62,
Organism=Drosophila melanogaster, GI21356559, Length=296, Percent_Identity=50.3378378378378, Blast_Score=296, Evalue=9e-81,
Organism=Drosophila melanogaster, GI28574296, Length=285, Percent_Identity=54.0350877192982, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI281363477, Length=252, Percent_Identity=32.1428571428571, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363475, Length=252, Percent_Identity=32.1428571428571, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363473, Length=252, Percent_Identity=32.1428571428571, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30666; Mature: 30535

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINENTRVAVQGITGTEGAFHARRMIEYGTKVVAGVTPGKGGLVHDGVPVFDSMREA
CEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCEEECCCCHHHHHHHH
AQETAPDVSVIFVPAPYAADAVMEATEAGIKLVVCPAEGIPVLDTVLARRYLEERKVMLI
HHHCCCCEEEEEEECCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEE
GPNTPGIISPGKCKVGLMAGYIHRQGSVGVVSRSGTLTYEAVHQLSRKGIGQSTCLGIGG
CCCCCCCCCCCCCEEEEEEHEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCC
DPVVGLSFVDILQLYEEDPGTKAVVLIGEIGGSMEEKAAEFFRTTMTKPLIAYIAGVTAP
CCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PERRMGHAGAIISRNRGGAQEKIRALEDAGVIVVRNPAEIGDIVESALHLR
HHHHCCCCCEEEECCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SILINENTRVAVQGITGTEGAFHARRMIEYGTKVVAGVTPGKGGLVHDGVPVFDSMREA
EEEEECCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCEEECCCCHHHHHHHH
AQETAPDVSVIFVPAPYAADAVMEATEAGIKLVVCPAEGIPVLDTVLARRYLEERKVMLI
HHHCCCCEEEEEEECCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEE
GPNTPGIISPGKCKVGLMAGYIHRQGSVGVVSRSGTLTYEAVHQLSRKGIGQSTCLGIGG
CCCCCCCCCCCCCEEEEEEHEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCC
DPVVGLSFVDILQLYEEDPGTKAVVLIGEIGGSMEEKAAEFFRTTMTKPLIAYIAGVTAP
CCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PERRMGHAGAIISRNRGGAQEKIRALEDAGVIVVRNPAEIGDIVESALHLR
HHHHCCCCCEEEECCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA