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The map label for this gene is sucC [H]

Identifier: 85860260

GI number: 85860260

Start: 2446323

End: 2447519

Strand: Direct

Name: sucC [H]

Synonym: SYN_02501

Alternate gene names: 85860260

Gene position: 2446323-2447519 (Clockwise)

Preceding gene: 85860259

Following gene: 85860261

Centisome position: 76.95

GC content: 58.48

Gene sequence:

>1197_bases
GTGCGACGCGACGGATTGCATGGGAAAATGAAGATTTATGAATATCAGGTAAAAGAGTTTTTCCGCAGCTTCGGCATACC
CACACCCCGGGGTGCTGCAGGAAAGACATCGGATGAAATTGTCACCGCCGCGCGATCGCTCGGCGTCATGCCGGTTGTCC
TGAAGTCACAGATCAAGGCGGGAGGCAGAGGCAAGGCCGGGGGAATCCGGACCGCAAACACCCTGGAAGAGGCGGGCCTG
CAGGCAATTGATCTTCTCGGCAGCCGGCTGGTGACAGCTCAAACCGGACCGGCCGGGGAGCAGGTCAACAGCCTGCTCCT
GGAAGAACGCATTGACCACGAACGGGAACTCTATGTGGGAATTCTGGTGGACAGGGAAACAGGGAGGCCGGCTCTTCTGG
TCAGCGGCGAAGGCGGTGTTGATATCGAAAAACTCGGCCGCGAAGCGCCGGGACAGATTCTCTGCGAATCCATTGATCCT
GCTTACGGCCTGCGGTCGTTTCAAGCTTCACGCGTCTTTCTTTCCCTTGGGCTTCCGTCTGCTTCAGCAGCCCGCTGCGC
GGAATTGTCTCTGAGCCTCTACAGGCTGTTCATGGAAATGGACTGTTCCGATGTGGAGATCAATCCCCTCGCCCTCACGA
CATCGGGAGAACCCGTCGCCCTGGATGGCAAAGTCAATGTAGACGACAACGCCCTGTACCGTCACCCGCCCCTGGCCTCC
CTGCATGAGAAGGAAGAGGAGAACGCCCTGGAAGCCGCCGCGTCGGCGCTGGGATTGAATTACATCAAATTGAACGGCAG
TGTGGGCTGCATGGTGAACGGGGCCGGGCTGGCCATGGCGACCATGGATCTCATCAAGATGACAGGCGCCGAGCCGGCGA
ATTTTCTCGATGTGGGAGGAGGGGCGAGCGTTTCCAGGATCAGAGAGGGGCTTCGAATCGTCCTTGCCGACAGGAATGTC
AAGATACTCTTCGTCAACATCTTCGGTGGCATACTCCGCTGCGACACCGTCGCCGAGGGTATTGCCCAGGGCGTAAGAGA
CCTGTCCATCAGCGTTCCGGTGGTGATCCGACTGGAGGGAACCAACAGGGATGAGGGACTGAAGATTCTATCCTCCTCAG
GGCTCAATTTTATCCAGGTAACCGACCTGAGGGAAGCCGTACTGCGGATCGGAGAAGAGGTCGCGAGGGCGGGATGA

Upstream 100 bases:

>100_bases
AGGGCAATACGGGAACGACTGCCCGGGGCCGAGGATCTCAACTTAAAGGCCATGCGCGCGGGCATGGCTGCCGCGCGAAA
GGCTGCACGGAAAGCGGCGG

Downstream 100 bases:

>100_bases
GCATTCTCATCAATGAGAATACGCGCGTGGCAGTGCAGGGGATTACAGGAACCGAAGGCGCTTTTCACGCGCGCCGGATG
ATCGAATACGGGACTAAGGT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRRDGLHGKMKIYEYQVKEFFRSFGIPTPRGAAGKTSDEIVTAARSLGVMPVVLKSQIKAGGRGKAGGIRTANTLEEAGL
QAIDLLGSRLVTAQTGPAGEQVNSLLLEERIDHERELYVGILVDRETGRPALLVSGEGGVDIEKLGREAPGQILCESIDP
AYGLRSFQASRVFLSLGLPSASAARCAELSLSLYRLFMEMDCSDVEINPLALTTSGEPVALDGKVNVDDNALYRHPPLAS
LHEKEEENALEAAASALGLNYIKLNGSVGCMVNGAGLAMATMDLIKMTGAEPANFLDVGGGASVSRIREGLRIVLADRNV
KILFVNIFGGILRCDTVAEGIAQGVRDLSISVPVVIRLEGTNRDEGLKILSSSGLNFIQVTDLREAVLRIGEEVARAG

Sequences:

>Translated_398_residues
MRRDGLHGKMKIYEYQVKEFFRSFGIPTPRGAAGKTSDEIVTAARSLGVMPVVLKSQIKAGGRGKAGGIRTANTLEEAGL
QAIDLLGSRLVTAQTGPAGEQVNSLLLEERIDHERELYVGILVDRETGRPALLVSGEGGVDIEKLGREAPGQILCESIDP
AYGLRSFQASRVFLSLGLPSASAARCAELSLSLYRLFMEMDCSDVEINPLALTTSGEPVALDGKVNVDDNALYRHPPLAS
LHEKEEENALEAAASALGLNYIKLNGSVGCMVNGAGLAMATMDLIKMTGAEPANFLDVGGGASVSRIREGLRIVLADRNV
KILFVNIFGGILRCDTVAEGIAQGVRDLSISVPVVIRLEGTNRDEGLKILSSSGLNFIQVTDLREAVLRIGEEVARAG
>Mature_398_residues
MRRDGLHGKMKIYEYQVKEFFRSFGIPTPRGAAGKTSDEIVTAARSLGVMPVVLKSQIKAGGRGKAGGIRTANTLEEAGL
QAIDLLGSRLVTAQTGPAGEQVNSLLLEERIDHERELYVGILVDRETGRPALLVSGEGGVDIEKLGREAPGQILCESIDP
AYGLRSFQASRVFLSLGLPSASAARCAELSLSLYRLFMEMDCSDVEINPLALTTSGEPVALDGKVNVDDNALYRHPPLAS
LHEKEEENALEAAASALGLNYIKLNGSVGCMVNGAGLAMATMDLIKMTGAEPANFLDVGGGASVSRIREGLRIVLADRNV
KILFVNIFGGILRCDTVAEGIAQGVRDLSISVPVVIRLEGTNRDEGLKILSSSGLNFIQVTDLREAVLRIGEEVARAG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=398, Percent_Identity=39.6984924623116, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=39.1644908616188, Blast_Score=284, Evalue=8e-77,
Organism=Homo sapiens, GI294862256, Length=388, Percent_Identity=37.3711340206186, Blast_Score=268, Evalue=5e-72,
Organism=Escherichia coli, GI1786948, Length=381, Percent_Identity=44.8818897637795, Blast_Score=328, Evalue=4e-91,
Organism=Caenorhabditis elegans, GI17567829, Length=385, Percent_Identity=36.8831168831169, Blast_Score=277, Evalue=7e-75,
Organism=Caenorhabditis elegans, GI17539378, Length=389, Percent_Identity=37.7892030848329, Blast_Score=271, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=38.676844783715, Blast_Score=294, Evalue=1e-80,
Organism=Drosophila melanogaster, GI161078106, Length=387, Percent_Identity=41.8604651162791, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24645208, Length=387, Percent_Identity=41.8604651162791, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=42.2680412371134, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=42.2680412371134, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI21356231, Length=385, Percent_Identity=38.7012987012987, Blast_Score=270, Evalue=1e-72,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42355; Mature: 42355

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRDGLHGKMKIYEYQVKEFFRSFGIPTPRGAAGKTSDEIVTAARSLGVMPVVLKSQIKA
CCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCC
GGRGKAGGIRTANTLEEAGLQAIDLLGSRLVTAQTGPAGEQVNSLLLEERIDHERELYVG
CCCCCCCCCCCHHHHHHHCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
ILVDRETGRPALLVSGEGGVDIEKLGREAPGQILCESIDPAYGLRSFQASRVFLSLGLPS
EEEECCCCCCEEEEECCCCCCHHHHCCCCCCHHHHHCCCCHHHHHHHHHCEEEEEECCCC
ASAARCAELSLSLYRLFMEMDCSDVEINPLALTTSGEPVALDGKVNVDDNALYRHPPLAS
CHHHHHHHHHHHHHHHHHHCCCCCCEECEEEEECCCCEEEECCEECCCCCCEECCCCCHH
LHEKEEENALEAAASALGLNYIKLNGSVGCMVNGAGLAMATMDLIKMTGAEPANFLDVGG
HHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCC
GASVSRIREGLRIVLADRNVKILFVNIFGGILRCDTVAEGIAQGVRDLSISVPVVIRLEG
CCCHHHHHCCEEEEEECCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHCEEECEEEEEEEC
TNRDEGLKILSSSGLNFIQVTDLREAVLRIGEEVARAG
CCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRDGLHGKMKIYEYQVKEFFRSFGIPTPRGAAGKTSDEIVTAARSLGVMPVVLKSQIKA
CCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCC
GGRGKAGGIRTANTLEEAGLQAIDLLGSRLVTAQTGPAGEQVNSLLLEERIDHERELYVG
CCCCCCCCCCCHHHHHHHCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
ILVDRETGRPALLVSGEGGVDIEKLGREAPGQILCESIDPAYGLRSFQASRVFLSLGLPS
EEEECCCCCCEEEEECCCCCCHHHHCCCCCCHHHHHCCCCHHHHHHHHHCEEEEEECCCC
ASAARCAELSLSLYRLFMEMDCSDVEINPLALTTSGEPVALDGKVNVDDNALYRHPPLAS
CHHHHHHHHHHHHHHHHHHCCCCCCEECEEEEECCCCEEEECCEECCCCCCEECCCCCHH
LHEKEEENALEAAASALGLNYIKLNGSVGCMVNGAGLAMATMDLIKMTGAEPANFLDVGG
HHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCC
GASVSRIREGLRIVLADRNVKILFVNIFGGILRCDTVAEGIAQGVRDLSISVPVVIRLEG
CCCHHHHHCCEEEEEECCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHCEEECEEEEEEEC
TNRDEGLKILSSSGLNFIQVTDLREAVLRIGEEVARAG
CCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA