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The map label for this gene is nreB [H]

Identifier: 85860163

GI number: 85860163

Start: 2369464

End: 2371212

Strand: Direct

Name: nreB [H]

Synonym: SYN_00776

Alternate gene names: 85860163

Gene position: 2369464-2371212 (Clockwise)

Preceding gene: 85860161

Following gene: 85860164

Centisome position: 74.53

GC content: 47.74

Gene sequence:

>1749_bases
ATGATGATGAAAAATCCCCAAACATACCGACTGCCCTTACTTTCTGAGAGCTGCTCAGTGCGCTCATCGCAGCAGCCGGC
TCTGAATTCGGTACAGGATGAGATTCATCCCCTTCTGAAGAAAGCCTTTTCAGAAAATATCCGCAGCAGGGAACATGGAC
GGAAGCTGAGGAAAAATCTTCCTTCTGATGAAAATTTATTAAATCGTTATAAAGTATTTTTTGATTCCGCCCCCGTGGGA
TGCATCATCATCAACGAAAAGGGCTATATCAGGCATATCAACGGAACCGGCGCTGCCATGTTGAACAGCAGCGATATAAA
CCAGCTTCAGGGAAAATCTTTTTTCCGCTTTATTTCCAGGGAAGATCGCCTCATGTTTCTTGCGCATCTGAAGAGCTGCT
CCGAAAGCGGAACGAATGAAAACATAGAAGTTCACCTTCGAACCTGGAATCGTCAGCCGCACATTCCCGTGCAGATTCAT
ACCGTTTTCCATGACGCTGATCCTGGGAGCAAACCTTTTTTTCTCTCCGTCATAACCAACATCAGCGAACACAAGCAGAT
GGAAGAGGCCTTGAGACGCAGTGAGGCCTGTTATCGCCATATCGTGGAAGATCATACGGAAATGATCTGCAGCTGTTTAC
GGAACTGGAAAATCACCTTTGTCAACGAAGCCATGTGCAATGTTTTCGGGACACCCCGTGACGAATTTATCGGGATGCCA
CTTGTCAAGTTCATCGACAAACAGGATCGGAAAAAAGTAAAGGAACTGCTGGCTTCACTGAATTCTTCCAACCCCATAAA
AACCGTGGAACACCGCGTGGTGATGCCCGATGGGCAAAGCCGCTGGCATCGCTGGATTCACAGGGTCATCTATAACCGCA
AAGGGCTGTTTGTGGAATATCAATCTGCGGGCCGTGACATAACCGAGCAGAAAGAAACTCAGGAAGCGTTGCTGAAAGCT
CACAGCGAACTGGAACAGAAGGTCGGTGAGCGCACAGCTGAACTGGCAAGGATTAATGAAACTCTCAGGGAAGAAATCGC
GGAACACAAGGAAACACAGAGAAAATTTCTCGCCAGTCATGAACAGCTCCGGGCACTGACATCTGACTTGATTACAACCG
AAGAGAGAGAACGAAGACTCATTGCCACAGAGCTTCACGACCATATCGGTCAGACATTGGCCGTTACCCGGATCAAGCTC
GAGATGCTGCATGCGTTAGCGTCATACAGCGGTTTTGCCGAAGCGCTGGAGGAAATTCAAGGTTTTGTCAAGCAGGCCAT
CCAGGAAACCCGTTCCCTTATGACAAAATTAAGCCCTCCGGTATTTTACGAACTCGGTTTGACGGCCGCTTTGGAATGGC
TGGTCCAGCACTTCGACGAACAGCATAACCTGAAGATTGTTTATAAAGGAATGAGCAATCATTTATCGCTGAAACAGGAT
ATTCAAATTCTTCTTCTGCAGGCGACGCGGGAGCTCCTGATGAACGTCGTAAAGCATGCCGGTGTGGAAAAAGCGGAAGT
TATCCTAAAAGCCAACAGGAAGCAGATTCAGATCGATGTCATCGATCATGGTTCAGGATTTGACGTATCACAAATCGGAA
CACCCGTAGACTGGAGAGGAGGTTTCGGTATCTTCAGCATTCATGAACGATTGAAGAATCTCGGGGGTGAACTCCAGATT
CGCTCAAAACGCGGAAAGGGGACACATTTTACCCTTATCGCTCCCCATAACACCAGAGACGGCAATTAA

Upstream 100 bases:

>100_bases
GAGTATAAAAATGTTTGAATCATTCATTATCGCGAGTTGACTGTGTATTTCTCGAGATTCATGACGTGTTTCAGAGTTCA
GCCTAATTAAGCAAGTTGAA

Downstream 100 bases:

>100_bases
AAGGAGAGAGAAAAATGGCTATTACCGTCATACTCGCCGACGATCATAAAATCATTCGTGATGGGCTGCGAACACTAATT
GAATCACAACAAGGCATGCA

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MMMKNPQTYRLPLLSESCSVRSSQQPALNSVQDEIHPLLKKAFSENIRSREHGRKLRKNLPSDENLLNRYKVFFDSAPVG
CIIINEKGYIRHINGTGAAMLNSSDINQLQGKSFFRFISREDRLMFLAHLKSCSESGTNENIEVHLRTWNRQPHIPVQIH
TVFHDADPGSKPFFLSVITNISEHKQMEEALRRSEACYRHIVEDHTEMICSCLRNWKITFVNEAMCNVFGTPRDEFIGMP
LVKFIDKQDRKKVKELLASLNSSNPIKTVEHRVVMPDGQSRWHRWIHRVIYNRKGLFVEYQSAGRDITEQKETQEALLKA
HSELEQKVGERTAELARINETLREEIAEHKETQRKFLASHEQLRALTSDLITTEERERRLIATELHDHIGQTLAVTRIKL
EMLHALASYSGFAEALEEIQGFVKQAIQETRSLMTKLSPPVFYELGLTAALEWLVQHFDEQHNLKIVYKGMSNHLSLKQD
IQILLLQATRELLMNVVKHAGVEKAEVILKANRKQIQIDVIDHGSGFDVSQIGTPVDWRGGFGIFSIHERLKNLGGELQI
RSKRGKGTHFTLIAPHNTRDGN

Sequences:

>Translated_582_residues
MMMKNPQTYRLPLLSESCSVRSSQQPALNSVQDEIHPLLKKAFSENIRSREHGRKLRKNLPSDENLLNRYKVFFDSAPVG
CIIINEKGYIRHINGTGAAMLNSSDINQLQGKSFFRFISREDRLMFLAHLKSCSESGTNENIEVHLRTWNRQPHIPVQIH
TVFHDADPGSKPFFLSVITNISEHKQMEEALRRSEACYRHIVEDHTEMICSCLRNWKITFVNEAMCNVFGTPRDEFIGMP
LVKFIDKQDRKKVKELLASLNSSNPIKTVEHRVVMPDGQSRWHRWIHRVIYNRKGLFVEYQSAGRDITEQKETQEALLKA
HSELEQKVGERTAELARINETLREEIAEHKETQRKFLASHEQLRALTSDLITTEERERRLIATELHDHIGQTLAVTRIKL
EMLHALASYSGFAEALEEIQGFVKQAIQETRSLMTKLSPPVFYELGLTAALEWLVQHFDEQHNLKIVYKGMSNHLSLKQD
IQILLLQATRELLMNVVKHAGVEKAEVILKANRKQIQIDVIDHGSGFDVSQIGTPVDWRGGFGIFSIHERLKNLGGELQI
RSKRGKGTHFTLIAPHNTRDGN
>Mature_582_residues
MMMKNPQTYRLPLLSESCSVRSSQQPALNSVQDEIHPLLKKAFSENIRSREHGRKLRKNLPSDENLLNRYKVFFDSAPVG
CIIINEKGYIRHINGTGAAMLNSSDINQLQGKSFFRFISREDRLMFLAHLKSCSESGTNENIEVHLRTWNRQPHIPVQIH
TVFHDADPGSKPFFLSVITNISEHKQMEEALRRSEACYRHIVEDHTEMICSCLRNWKITFVNEAMCNVFGTPRDEFIGMP
LVKFIDKQDRKKVKELLASLNSSNPIKTVEHRVVMPDGQSRWHRWIHRVIYNRKGLFVEYQSAGRDITEQKETQEALLKA
HSELEQKVGERTAELARINETLREEIAEHKETQRKFLASHEQLRALTSDLITTEERERRLIATELHDHIGQTLAVTRIKL
EMLHALASYSGFAEALEEIQGFVKQAIQETRSLMTKLSPPVFYELGLTAALEWLVQHFDEQHNLKIVYKGMSNHLSLKQD
IQILLLQATRELLMNVVKHAGVEKAEVILKANRKQIQIDVIDHGSGFDVSQIGTPVDWRGGFGIFSIHERLKNLGGELQI
RSKRGKGTHFTLIAPHNTRDGN

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=202, Percent_Identity=28.7128712871287, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66887; Mature: 66887

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMKNPQTYRLPLLSESCSVRSSQQPALNSVQDEIHPLLKKAFSENIRSREHGRKLRKNL
CCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSDENLLNRYKVFFDSAPVGCIIINEKGYIRHINGTGAAMLNSSDINQLQGKSFFRFISR
CCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHCC
EDRLMFLAHLKSCSESGTNENIEVHLRTWNRQPHIPVQIHTVFHDADPGSKPFFLSVITN
CCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCHHHHHHC
ISEHKQMEEALRRSEACYRHIVEDHTEMICSCLRNWKITFVNEAMCNVFGTPRDEFIGMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCHHHHCCCH
LVKFIDKQDRKKVKELLASLNSSNPIKTVEHRVVMPDGQSRWHRWIHRVIYNRKGLFVEY
HHHHHCHHHHHHHHHHHHHCCCCCCCCHHHCEEECCCCHHHHHHHHHHHHHCCCCCEEEE
QSAGRDITEQKETQEALLKAHSELEQKVGERTAELARINETLREEIAEHKETQRKFLASH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQLRALTSDLITTEERERRLIATELHDHIGQTLAVTRIKLEMLHALASYSGFAEALEEIQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVKQAIQETRSLMTKLSPPVFYELGLTAALEWLVQHFDEQHNLKIVYKGMSNHLSLKQD
HHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHH
IQILLLQATRELLMNVVKHAGVEKAEVILKANRKQIQIDVIDHGSGFDVSQIGTPVDWRG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEECCCCCCHHHCCCCCCCCC
GFGIFSIHERLKNLGGELQIRSKRGKGTHFTLIAPHNTRDGN
CCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MMMKNPQTYRLPLLSESCSVRSSQQPALNSVQDEIHPLLKKAFSENIRSREHGRKLRKNL
CCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSDENLLNRYKVFFDSAPVGCIIINEKGYIRHINGTGAAMLNSSDINQLQGKSFFRFISR
CCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHCC
EDRLMFLAHLKSCSESGTNENIEVHLRTWNRQPHIPVQIHTVFHDADPGSKPFFLSVITN
CCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCHHHHHHC
ISEHKQMEEALRRSEACYRHIVEDHTEMICSCLRNWKITFVNEAMCNVFGTPRDEFIGMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCHHHHCCCH
LVKFIDKQDRKKVKELLASLNSSNPIKTVEHRVVMPDGQSRWHRWIHRVIYNRKGLFVEY
HHHHHCHHHHHHHHHHHHHCCCCCCCCHHHCEEECCCCHHHHHHHHHHHHHCCCCCEEEE
QSAGRDITEQKETQEALLKAHSELEQKVGERTAELARINETLREEIAEHKETQRKFLASH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQLRALTSDLITTEERERRLIATELHDHIGQTLAVTRIKLEMLHALASYSGFAEALEEIQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVKQAIQETRSLMTKLSPPVFYELGLTAALEWLVQHFDEQHNLKIVYKGMSNHLSLKQD
HHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHH
IQILLLQATRELLMNVVKHAGVEKAEVILKANRKQIQIDVIDHGSGFDVSQIGTPVDWRG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEECCCCCCHHHCCCCCCCCC
GFGIFSIHERLKNLGGELQIRSKRGKGTHFTLIAPHNTRDGN
CCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA