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The map label for this gene is nreC [H]

Identifier: 85860164

GI number: 85860164

Start: 2371227

End: 2371874

Strand: Direct

Name: nreC [H]

Synonym: SYN_00775

Alternate gene names: 85860164

Gene position: 2371227-2371874 (Clockwise)

Preceding gene: 85860163

Following gene: 85860165

Centisome position: 74.58

GC content: 50.0

Gene sequence:

>648_bases
ATGGCTATTACCGTCATACTCGCCGACGATCATAAAATCATTCGTGATGGGCTGCGAACACTAATTGAATCACAACAAGG
CATGCAGGTCATCGCTGAAGCGGAAAATGGCAGGGAAACCATCAAACTGGCAAAAGAACTTCAACCCAACGTAGTGATCA
TGGATATCTCCATGCCCGATTTGAACGGTATCGACGCAACCCGGGAAATTGTCAACAGCATTCCGGGGGTAAAGGTTATC
GCGCTTTCCATGCATTCCGACCGGCGGTTCGTATCGGGAATGCTTTCCGCCGGGGCTTCCGGGTATCTCTTGAAAGACTG
CGCTTTTGAAGAACTCGCCAAGGCCATTCGAACCGTCGTGACTAATCATACCTATCTGAGTCCCATGATCTCCGATATCG
TCGTGAAAAGCTATATCAACAAATCCCCGGAGACAACGACGGAAAACGCTCCCTCTCTGACCGCCCGGGAGCGGGAAATG
CTGCAGCTTATGGCTGAAGGAATGACAGCCAAGGAAATTGCGGCTCATCTTTTTGTCAGCGTCAAGACGGTAGAGACACA
CCGACGGAATATCGCCCAAAAATTGAATATCAACCGGGCGGCCGAGTTGATCAAATATGCGATCAGGGAAGGTCTGGTTA
CACTGTAA

Upstream 100 bases:

>100_bases
GGGGTGAACTCCAGATTCGCTCAAAACGCGGAAAGGGGACACATTTTACCCTTATCGCTCCCCATAACACCAGAGACGGC
AATTAAAAGGAGAGAGAAAA

Downstream 100 bases:

>100_bases
AAGACACAACCCGGCGCGTCCCGCATGCATTTTTTCAACAGCTGTCATAAACACCAGAAGGGCAGTTATTCCGAGCCATT
CGCATTCTCATGTTTTTCAA

Product: two-component response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MAITVILADDHKIIRDGLRTLIESQQGMQVIAEAENGRETIKLAKELQPNVVIMDISMPDLNGIDATREIVNSIPGVKVI
ALSMHSDRRFVSGMLSAGASGYLLKDCAFEELAKAIRTVVTNHTYLSPMISDIVVKSYINKSPETTTENAPSLTAREREM
LQLMAEGMTAKEIAAHLFVSVKTVETHRRNIAQKLNINRAAELIKYAIREGLVTL

Sequences:

>Translated_215_residues
MAITVILADDHKIIRDGLRTLIESQQGMQVIAEAENGRETIKLAKELQPNVVIMDISMPDLNGIDATREIVNSIPGVKVI
ALSMHSDRRFVSGMLSAGASGYLLKDCAFEELAKAIRTVVTNHTYLSPMISDIVVKSYINKSPETTTENAPSLTAREREM
LQLMAEGMTAKEIAAHLFVSVKTVETHRRNIAQKLNINRAAELIKYAIREGLVTL
>Mature_214_residues
AITVILADDHKIIRDGLRTLIESQQGMQVIAEAENGRETIKLAKELQPNVVIMDISMPDLNGIDATREIVNSIPGVKVIA
LSMHSDRRFVSGMLSAGASGYLLKDCAFEELAKAIRTVVTNHTYLSPMISDIVVKSYINKSPETTTENAPSLTAREREML
QLMAEGMTAKEIAAHLFVSVKTVETHRRNIAQKLNINRAAELIKYAIREGLVTL

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=36.9668246445498, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=39.2156862745098, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788521, Length=212, Percent_Identity=33.0188679245283, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=30.3921568627451, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787473, Length=187, Percent_Identity=34.7593582887701, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788546, Length=211, Percent_Identity=28.436018957346, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=23.1884057971014, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23714; Mature: 23583

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITVILADDHKIIRDGLRTLIESQQGMQVIAEAENGRETIKLAKELQPNVVIMDISMPD
CEEEEEEECCHHHHHHHHHHHHHCCCCHHEEHHCCCCHHHHHHHHHCCCCEEEEEECCCC
LNGIDATREIVNSIPGVKVIALSMHSDRRFVSGMLSAGASGYLLKDCAFEELAKAIRTVV
CCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TNHTYLSPMISDIVVKSYINKSPETTTENAPSLTAREREMLQLMAEGMTAKEIAAHLFVS
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VKTVETHRRNIAQKLNINRAAELIKYAIREGLVTL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AITVILADDHKIIRDGLRTLIESQQGMQVIAEAENGRETIKLAKELQPNVVIMDISMPD
EEEEEEECCHHHHHHHHHHHHHCCCCHHEEHHCCCCHHHHHHHHHCCCCEEEEEECCCC
LNGIDATREIVNSIPGVKVIALSMHSDRRFVSGMLSAGASGYLLKDCAFEELAKAIRTVV
CCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TNHTYLSPMISDIVVKSYINKSPETTTENAPSLTAREREMLQLMAEGMTAKEIAAHLFVS
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VKTVETHRRNIAQKLNINRAAELIKYAIREGLVTL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]