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The map label for this gene is czcN [H]

Identifier: 85860087

GI number: 85860087

Start: 2293419

End: 2294027

Strand: Direct

Name: czcN [H]

Synonym: SYN_01562

Alternate gene names: 85860087

Gene position: 2293419-2294027 (Clockwise)

Preceding gene: 85860086

Following gene: 85860099

Centisome position: 72.14

GC content: 40.23

Gene sequence:

>609_bases
ATGAAATCAAATTATGAAATATATCGAACACTTCTGTCTCGCATTGCCGCATTTATATGTTTGTTTTTTTTCTTCACTAC
ACAGAGTTACTGGGAATCAAAGAATGAATACATTTCATTTTCCTTGTTCTTAGCAGGCATCATTCTTGTCGCTATTGCCT
CATTGGGGAGAATGTGGTGTTCACTTTACATTGCCGGCTACAAAGATGACATCCTGGTTACAAAAGGTCCGTATTCCCTG
TGTCGAAACCCTTTGTATTTTTTCAGCATGATCGGAGTGGCCGGAATTGGCTTTGCTACCGAAACTCTCACTTTTCCAAT
AGCTTTCGCTATCCTCTTTGCCCTCTATTATCCTTCTGTTATCAAAAGTGAAGAAAAACGCCTCAAGCAATTATTTGGAA
TTGAGTTTGAGCGATACAAAAGCAGAGTGCCTGCTTTTTTCCCAAAGCTCTCGACCTTTGATGAACCTGAAATTTACTCT
GTTAAACCGGCAGTTTACAGGGACCACATGTTCAGTGCCCTGTGGTTTGTCTGGCTGGTTGGCATACTTGAGGTCATTGA
GGGATTTAAGGAAATCGGACTGCTTAAAGCATTATGGACAATTTATTAA

Upstream 100 bases:

>100_bases
GGATTCCGGGAGGCCGGTTTCGATGATCCGGCGTTTTCTGAAACGTAACTTTTAAAGGGAAAAAATTCTTCCGTGAAATA
CGATTGGAAAAGATAAACAA

Downstream 100 bases:

>100_bases
TTCATGTCAGCAATCAGACCTGACAAAACGCTTATATTTTCTCTCTTTATTTGTTAAGAGAGCTGCGGCCGATTGAGATG
ATTTTCATTGGCTGGCGGAA

Product: nickel-cobalt-cadmium resistance protein

Products: NA

Alternate protein names: Cation efflux system protein CzcN [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKSNYEIYRTLLSRIAAFICLFFFFTTQSYWESKNEYISFSLFLAGIILVAIASLGRMWCSLYIAGYKDDILVTKGPYSL
CRNPLYFFSMIGVAGIGFATETLTFPIAFAILFALYYPSVIKSEEKRLKQLFGIEFERYKSRVPAFFPKLSTFDEPEIYS
VKPAVYRDHMFSALWFVWLVGILEVIEGFKEIGLLKALWTIY

Sequences:

>Translated_202_residues
MKSNYEIYRTLLSRIAAFICLFFFFTTQSYWESKNEYISFSLFLAGIILVAIASLGRMWCSLYIAGYKDDILVTKGPYSL
CRNPLYFFSMIGVAGIGFATETLTFPIAFAILFALYYPSVIKSEEKRLKQLFGIEFERYKSRVPAFFPKLSTFDEPEIYS
VKPAVYRDHMFSALWFVWLVGILEVIEGFKEIGLLKALWTIY
>Mature_202_residues
MKSNYEIYRTLLSRIAAFICLFFFFTTQSYWESKNEYISFSLFLAGIILVAIASLGRMWCSLYIAGYKDDILVTKGPYSL
CRNPLYFFSMIGVAGIGFATETLTFPIAFAILFALYYPSVIKSEEKRLKQLFGIEFERYKSRVPAFFPKLSTFDEPEIYS
VKPAVYRDHMFSALWFVWLVGILEVIEGFKEIGLLKALWTIY

Specific function: Component of the CZC cation-efflux system that confers resistance to cobalt, zinc and cadmium [H]

COG id: COG2020

COG function: function code O; Putative protein-S-isoprenylcysteine methyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To A.xylosoxydans nccN [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007269 [H]

Pfam domain/function: PF04140 ICMT [H]

EC number: NA

Molecular weight: Translated: 23452; Mature: 23452

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNYEIYRTLLSRIAAFICLFFFFTTQSYWESKNEYISFSLFLAGIILVAIASLGRMWC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYIAGYKDDILVTKGPYSLCRNPLYFFSMIGVAGIGFATETLTFPIAFAILFALYYPSV
HHHHCCCCCCEEEECCCHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IKSEEKRLKQLFGIEFERYKSRVPAFFPKLSTFDEPEIYSVKPAVYRDHMFSALWFVWLV
HHHHHHHHHHHHCCHHHHHHHHCCHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
GILEVIEGFKEIGLLKALWTIY
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSNYEIYRTLLSRIAAFICLFFFFTTQSYWESKNEYISFSLFLAGIILVAIASLGRMWC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYIAGYKDDILVTKGPYSLCRNPLYFFSMIGVAGIGFATETLTFPIAFAILFALYYPSV
HHHHCCCCCCEEEECCCHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IKSEEKRLKQLFGIEFERYKSRVPAFFPKLSTFDEPEIYSVKPAVYRDHMFSALWFVWLV
HHHHHHHHHHHHCCHHHHHHHHCCHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
GILEVIEGFKEIGLLKALWTIY
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9044283; 7766206 [H]