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The map label for this gene is queC

Identifier: 85860086

GI number: 85860086

Start: 2292671

End: 2293366

Strand: Direct

Name: queC

Synonym: SYN_01561

Alternate gene names: 85860086

Gene position: 2292671-2293366 (Clockwise)

Preceding gene: 85860085

Following gene: 85860087

Centisome position: 72.11

GC content: 55.32

Gene sequence:

>696_bases
ATGAGTCCAAAGAAAAAGGCCGTTGTCCTGCTCAGCGGCGGGCTGGATTCCGCCACCACCATGGCAATCGCGAAAGCGGA
AAACTATGAACTTTACGCCCTCACCTTCCAGTACGGCCAGCGCCACGCCGTCGAACTGGAGGCGGCCAGGCGCATCGCCG
CCGCTCTGGGCGCGAAGGAGCATCTTTTTATTTCTATTGATTTAAGAATCATCGGGGGATCAGCCCTTACAGGGCCTTTT
GAAGTCCCGAAAAAACAGGAGGGAGAAGAGACATCGGCGGAAATTCCCGTAACCTACGTCCCAGCCAGAAACACCATCTT
CCTCTCCTACGCCCTGGCATGGGCAGAGGTCTTACAGATATCGGAAATCTTTATCGGCGTGAACGCGGTGGATTACAGCG
GATATCCCGACTGCCGTCCTGAATATATTACAGCCTTTGAAGCCATGGCCAATCTCGCCATCAAGGCGGCTGTGGAAGGC
ACAATGCGCGTGAAAATCCGCACCCCGCTGATTGATCTCTCCAAGGCGGACATCATTCGCAAGGGCATGGCCCTGAGTGT
GGACTATGGACTGACCCACAGCTGCTACGATCCCTTGCCTGATGGAAAGCCCTGCGGGCAATGCGACAGTTGTCATCTCC
GCAGAAAGGGATTCCGGGAGGCCGGTTTCGATGATCCGGCGTTTTCTGAAACGTAA

Upstream 100 bases:

>100_bases
GTCGCATGTTTACATCATATCGAGGATACAGAGACGAAGCCGGTGCAGTCAGATGAGGAAAGACGACCTGGCATAAAAAG
TTAAAACATGAGGCATTTGT

Downstream 100 bases:

>100_bases
CTTTTAAAGGGAAAAAATTCTTCCGTGAAATACGATTGGAAAAGATAAACAAATGAAATCAAATTATGAAATATATCGAA
CACTTCTGTCTCGCATTGCC

Product: queuosine biosynthesis protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSPKKKAVVLLSGGLDSATTMAIAKAENYELYALTFQYGQRHAVELEAARRIAAALGAKEHLFISIDLRIIGGSALTGPF
EVPKKQEGEETSAEIPVTYVPARNTIFLSYALAWAEVLQISEIFIGVNAVDYSGYPDCRPEYITAFEAMANLAIKAAVEG
TMRVKIRTPLIDLSKADIIRKGMALSVDYGLTHSCYDPLPDGKPCGQCDSCHLRRKGFREAGFDDPAFSET

Sequences:

>Translated_231_residues
MSPKKKAVVLLSGGLDSATTMAIAKAENYELYALTFQYGQRHAVELEAARRIAAALGAKEHLFISIDLRIIGGSALTGPF
EVPKKQEGEETSAEIPVTYVPARNTIFLSYALAWAEVLQISEIFIGVNAVDYSGYPDCRPEYITAFEAMANLAIKAAVEG
TMRVKIRTPLIDLSKADIIRKGMALSVDYGLTHSCYDPLPDGKPCGQCDSCHLRRKGFREAGFDDPAFSET
>Mature_230_residues
SPKKKAVVLLSGGLDSATTMAIAKAENYELYALTFQYGQRHAVELEAARRIAAALGAKEHLFISIDLRIIGGSALTGPFE
VPKKQEGEETSAEIPVTYVPARNTIFLSYALAWAEVLQISEIFIGVNAVDYSGYPDCRPEYITAFEAMANLAIKAAVEGT
MRVKIRTPLIDLSKADIIRKGMALSVDYGLTHSCYDPLPDGKPCGQCDSCHLRRKGFREAGFDDPAFSET

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=231, Percent_Identity=34.6320346320346, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_SYNAS (Q2LVL3)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_462288.1
- ProteinModelPortal:   Q2LVL3
- SMR:   Q2LVL3
- STRING:   Q2LVL3
- GeneID:   3883502
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_01561
- NMPDR:   fig|56780.10.peg.2224
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q2LVL3
- BioCyc:   SACI56780:SYN_01561-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25171; Mature: 25040

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPKKKAVVLLSGGLDSATTMAIAKAENYELYALTFQYGQRHAVELEAARRIAAALGAKE
CCCCCEEEEEEECCCCCHHEEEEEECCCCEEEEEEEECCCCEEEHHHHHHHHHHHHCCCC
HLFISIDLRIIGGSALTGPFEVPKKQEGEETSAEIPVTYVPARNTIFLSYALAWAEVLQI
EEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHH
SEIFIGVNAVDYSGYPDCRPEYITAFEAMANLAIKAAVEGTMRVKIRTPLIDLSKADIIR
HHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEECCEEEEEEECCEECCCHHHHHH
KGMALSVDYGLTHSCYDPLPDGKPCGQCDSCHLRRKGFREAGFDDPAFSET
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
SPKKKAVVLLSGGLDSATTMAIAKAENYELYALTFQYGQRHAVELEAARRIAAALGAKE
CCCCEEEEEEECCCCCHHEEEEEECCCCEEEEEEEECCCCEEEHHHHHHHHHHHHCCCC
HLFISIDLRIIGGSALTGPFEVPKKQEGEETSAEIPVTYVPARNTIFLSYALAWAEVLQI
EEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHH
SEIFIGVNAVDYSGYPDCRPEYITAFEAMANLAIKAAVEGTMRVKIRTPLIDLSKADIIR
HHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEECCEEEEEEECCEECCCHHHHHH
KGMALSVDYGLTHSCYDPLPDGKPCGQCDSCHLRRKGFREAGFDDPAFSET
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA