| Definition | Syntrophus aciditrophicus SB chromosome, complete genome. |
|---|---|
| Accession | NC_007759 |
| Length | 3,179,300 |
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The map label for this gene is paaF [C]
Identifier: 85859760
GI number: 85859760
Start: 1995851
End: 1996651
Strand: Direct
Name: paaF [C]
Synonym: SYN_01309
Alternate gene names: 85859760
Gene position: 1995851-1996651 (Clockwise)
Preceding gene: 85859759
Following gene: 85859762
Centisome position: 62.78
GC content: 54.68
Gene sequence:
>801_bases GTGACAGGGGGACAAAATCTCATGGCATATGAAACGATACTCCTCAAAATCGAGGGTAATATTGCAACGATAACGATCAA TCGCCCCCCCATGAATCCCCTGAACAGCGGAGTTTTCCGGGATGTCATTGCGGCCACTCGAGAAATCGAAGCCGACGATA ATGTCAAGGTCATCATTCTGGACAGCACCGGAGACAAGGCTTTCGCCGCCGGCGCCGACGTCAAGGAAATGGTTAATTTG ACGCCGGTCGAGATCTACGATTTCAGCCTGAACTTCCGCAAGGCCTGTGAATGTTTTGCAGCCAATCCGCTTCCTACGAT TGCCGTCATCAAGGGATTCGCCCTTGGAGGCGGCTGCGAAATGGCCATGGCCTGTGACCTTAGAATCGCTGCCGACAACG CAAAATTCGGTCAGCCGGAAATTAATCTGGGTGTGACTCCCGGAGCGGGCGGTACGCAGAGGTTGACCCGTCTGGTCGGC GCTGCCCGGGCCAAGGAGCTGATCCTTACGGGCGACATGATCGACGCGGCAACAGCGGAGAGAATCGGCCTCGTAAATAA AGTCGTGCCTCTGGCGGAACTGGATGCCGCTGTGGCCGCCCTGGCGGAGAAACTGGCGTCCAAACCGAAAGTCAGCCTGA AACTGTGCAAATCCGCGATCAACACGGCAGAGGATGTCGACATCAGCAGCGGTATCGCCTTTGAAGTTCTGACGTTCTCC CTTGCCAATGCATCTGCTGACAAGCTGGAGGGAATGAAGGCGCTTCTTGAAAAGCGTAAAGCGAATTTTCAAGACAAGTA G
Upstream 100 bases:
>100_bases AACAATGGACGTCCGCTGGAATCCCCCTCTATCCATCAAACTGCTGCTGAAATCAGGCAGGCTGGGTCGCAAAAACGGCG CCGGCTGGTACAAGTACTAA
Downstream 100 bases:
>100_bases GCTTCTATTCCTTAAAAGACGATTCGGAAGGGAAGCCTGATCTGGAAACCGGATTTCTCCCTGAAATTCAACATCCTGGA AATTTCAGCGTATCTGTTTA
Product: enoyl-CoA hydratase
Products: NA
Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]
Number of amino acids: Translated: 266; Mature: 265
Protein sequence:
>266_residues MTGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIILDSTGDKAFAAGADVKEMVNL TPVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCEMAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVG AARAKELILTGDMIDAATAERIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFS LANASADKLEGMKALLEKRKANFQDK
Sequences:
>Translated_266_residues MTGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIILDSTGDKAFAAGADVKEMVNL TPVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCEMAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVG AARAKELILTGDMIDAATAERIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFS LANASADKLEGMKALLEKRKANFQDK >Mature_265_residues TGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIILDSTGDKAFAAGADVKEMVNLT PVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCEMAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVGA ARAKELILTGDMIDAATAERIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFSL ANASADKLEGMKALLEKRKANFQDK
Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=261, Percent_Identity=42.5287356321839, Blast_Score=195, Evalue=4e-50, Organism=Homo sapiens, GI4502327, Length=250, Percent_Identity=36.8, Blast_Score=127, Evalue=1e-29, Organism=Homo sapiens, GI68989263, Length=212, Percent_Identity=32.0754716981132, Blast_Score=115, Evalue=6e-26, Organism=Homo sapiens, GI20127408, Length=198, Percent_Identity=35.3535353535354, Blast_Score=110, Evalue=9e-25, Organism=Homo sapiens, GI150378541, Length=252, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI31542718, Length=229, Percent_Identity=32.7510917030568, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=26.3636363636364, Blast_Score=85, Evalue=9e-17, Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=26.3636363636364, Blast_Score=85, Evalue=9e-17, Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=26.3636363636364, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI261878539, Length=114, Percent_Identity=39.4736842105263, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI70995211, Length=242, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI62530384, Length=225, Percent_Identity=25.7777777777778, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI213417737, Length=217, Percent_Identity=26.7281105990783, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI157694516, Length=217, Percent_Identity=26.7281105990783, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI37594469, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI37594471, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI157694520, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI295842266, Length=223, Percent_Identity=24.2152466367713, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI25453481, Length=263, Percent_Identity=24.3346007604563, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI51538573, Length=263, Percent_Identity=24.3346007604563, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4757968, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI49355787, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4757966, Length=252, Percent_Identity=24.6031746031746, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI51538581, Length=252, Percent_Identity=24.6031746031746, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI221136756, Length=236, Percent_Identity=25, Blast_Score=64, Evalue=9e-11, Organism=Homo sapiens, GI221136753, Length=236, Percent_Identity=25, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1787659, Length=265, Percent_Identity=35.0943396226415, Blast_Score=155, Evalue=3e-39, Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=32.6848249027237, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=29.8850574712644, Blast_Score=113, Evalue=2e-26, Organism=Escherichia coli, GI1788682, Length=197, Percent_Identity=38.0710659898477, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=33.206106870229, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=30.1526717557252, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1790281, Length=215, Percent_Identity=34.8837209302326, Blast_Score=100, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17554946, Length=259, Percent_Identity=37.8378378378378, Blast_Score=171, Evalue=3e-43, Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=38.0566801619433, Blast_Score=166, Evalue=8e-42, Organism=Caenorhabditis elegans, GI17540714, Length=240, Percent_Identity=37.0833333333333, Blast_Score=147, Evalue=7e-36, Organism=Caenorhabditis elegans, GI17558304, Length=190, Percent_Identity=33.1578947368421, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI25144276, Length=184, Percent_Identity=35.3260869565217, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17508953, Length=184, Percent_Identity=35.3260869565217, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17508951, Length=184, Percent_Identity=35.3260869565217, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17560910, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17549921, Length=218, Percent_Identity=26.1467889908257, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17534483, Length=251, Percent_Identity=26.2948207171315, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17536985, Length=264, Percent_Identity=24.6212121212121, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17535521, Length=220, Percent_Identity=25.9090909090909, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17540306, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6320241, Length=208, Percent_Identity=28.8461538461538, Blast_Score=87, Evalue=3e-18, Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=44.0613026819923, Blast_Score=215, Evalue=3e-56, Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=44.0613026819923, Blast_Score=215, Evalue=3e-56, Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=38.4905660377359, Blast_Score=162, Evalue=2e-40, Organism=Drosophila melanogaster, GI24650670, Length=257, Percent_Identity=31.5175097276265, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24583165, Length=190, Percent_Identity=28.4210526315789, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21357171, Length=239, Percent_Identity=30.5439330543933, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI19921018, Length=186, Percent_Identity=29.5698924731183, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI28571730, Length=267, Percent_Identity=29.2134831460674, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571729, Length=267, Percent_Identity=29.2134831460674, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI19922422, Length=263, Percent_Identity=24.3346007604563, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI19920382, Length=212, Percent_Identity=26.4150943396226, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI45550169, Length=145, Percent_Identity=31.7241379310345, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24654903, Length=212, Percent_Identity=21.6981132075472, Blast_Score=72, Evalue=3e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.116 [H]
Molecular weight: Translated: 28057; Mature: 27926
Theoretical pI: Translated: 4.88; Mature: 4.88
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIIL CCCCCCEEEEEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE DSTGDKAFAAGADVKEMVNLTPVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCE ECCCCCEEECCCCHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHCEECCCCCC MAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVGAARAKELILTGDMIDAATAE EEEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHH RIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFS HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCCCCEEEHHHHH LANASADKLEGMKALLEKRKANFQDK HCCCCHHHHHHHHHHHHHHHCCCCCC >Mature Secondary Structure TGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIIL CCCCCEEEEEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE DSTGDKAFAAGADVKEMVNLTPVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCE ECCCCCEEECCCCHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHCEECCCCCC MAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVGAARAKELILTGDMIDAATAE EEEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHH RIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFS HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCCCCEEEHHHHH LANASADKLEGMKALLEKRKANFQDK HCCCCHHHHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA