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The map label for this gene is folE2

Identifier: 85859762

GI number: 85859762

Start: 1997045

End: 1997812

Strand: Direct

Name: folE2

Synonym: SYN_01308

Alternate gene names: 85859762

Gene position: 1997045-1997812 (Clockwise)

Preceding gene: 85859760

Following gene: 85859763

Centisome position: 62.81

GC content: 46.88

Gene sequence:

>768_bases
ATGATCGATATTCAAAATCTGGAAGACCACAGAAAAATCAACATCCAGAAAGTCGGAGTCAAAGGCATCAATTATCCCAT
CGTTGTTCTGGATAAAGCAAAGGGCACGCAGCACGTGAACGCTTCCATAAACATGTACGTCGATCTGCCGCATCATTTCA
AGGGAACGCACATGAGCCGCTTTATCGAAGTCCTCAATGAGTTTCGGGGAGAAATCAACATCCGAACATTTCATACCATC
CTGGAAAAAGTCAGGGATAAACTCAAAGCAGAATCGGCACACATGGAAATCACGTTCCCATATTTCATCGAAAAAACAGC
CCCGGTTTCCGGAGCAAAAAGTCTGATGGACTACATTTGTGCTTTCAGCGGCATGAATGCCGAAAACAAAAAAGATTTTC
TCGTGGGCGTTGTGGTTCCGGTCACAACCGTCTGTCCCTGCTCCAAGGAAATCAGCTGCATGGGCGCCCACAATCAGCGG
AGTCATGTGACGGTCAAAGTCCGATTCAAAAAGTTCTTCTGGCTGGAGGACATCATCCGGCTCGTGGAAACATCAGCCAG
CGGCGAGGTCTATTCCCTTCTCAAGCGCGTGGATGAAAAATACGTGACGGAACAGGGCTATGCGAATCCCATGTTTGTGG
AGGATGTGGTCAGAAACGTCGCGGAACGTCTCAATGAAAATTCCAATCTCACCTGGTACAGCGTTGAAGCGGAAAACTTT
GAAAGCATTCATAATCATAATGCCTATGCCTACGTGGAAAAAGAGTGA

Upstream 100 bases:

>100_bases
TCTTATAATGTATAAGAGCTTTCATCATAAGCTACAGAAAATGGTTATGCGTATATTCTCTCATGAAAGAAGACATCAAC
ATTCCGCATGAAATAAGACT

Downstream 100 bases:

>100_bases
AGCCTATGCCTTCCGATCCTGTAAATTTCTTTAATATATACTCCCACGGCTTCATCAGGACGGCGATCTGCATTCCGGAT
GTCCGCGTCGCCGATACGGA

Product: cytoplasmic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIDIQNLEDHRKINIQKVGVKGINYPIVVLDKAKGTQHVNASINMYVDLPHHFKGTHMSRFIEVLNEFRGEINIRTFHTI
LEKVRDKLKAESAHMEITFPYFIEKTAPVSGAKSLMDYICAFSGMNAENKKDFLVGVVVPVTTVCPCSKEISCMGAHNQR
SHVTVKVRFKKFFWLEDIIRLVETSASGEVYSLLKRVDEKYVTEQGYANPMFVEDVVRNVAERLNENSNLTWYSVEAENF
ESIHNHNAYAYVEKE

Sequences:

>Translated_255_residues
MIDIQNLEDHRKINIQKVGVKGINYPIVVLDKAKGTQHVNASINMYVDLPHHFKGTHMSRFIEVLNEFRGEINIRTFHTI
LEKVRDKLKAESAHMEITFPYFIEKTAPVSGAKSLMDYICAFSGMNAENKKDFLVGVVVPVTTVCPCSKEISCMGAHNQR
SHVTVKVRFKKFFWLEDIIRLVETSASGEVYSLLKRVDEKYVTEQGYANPMFVEDVVRNVAERLNENSNLTWYSVEAENF
ESIHNHNAYAYVEKE
>Mature_255_residues
MIDIQNLEDHRKINIQKVGVKGINYPIVVLDKAKGTQHVNASINMYVDLPHHFKGTHMSRFIEVLNEFRGEINIRTFHTI
LEKVRDKLKAESAHMEITFPYFIEKTAPVSGAKSLMDYICAFSGMNAENKKDFLVGVVVPVTTVCPCSKEISCMGAHNQR
SHVTVKVRFKKFFWLEDIIRLVETSASGEVYSLLKRVDEKYVTEQGYANPMFVEDVVRNVAERLNENSNLTWYSVEAENF
ESIHNHNAYAYVEKE

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_SYNAS (Q2LUP0)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_461964.1
- ProteinModelPortal:   Q2LUP0
- SMR:   Q2LUP0
- STRING:   Q2LUP0
- GeneID:   3882569
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_01308
- NMPDR:   fig|56780.10.peg.1907
- eggNOG:   COG1469
- HOGENOM:   HBG626871
- OMA:   SLMDYEV
- BioCyc:   SACI56780:SYN_01308-MONOMER
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 29293; Mature: 29293

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIQNLEDHRKINIQKVGVKGINYPIVVLDKAKGTQHVNASINMYVDLPHHFKGTHMSR
CCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCEEECCEEEEEEECCCCCCCCHHHH
FIEVLNEFRGEINIRTFHTILEKVRDKLKAESAHMEITFPYFIEKTAPVSGAKSLMDYIC
HHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEHHEEECCCCCCHHHHHHHHHH
AFSGMNAENKKDFLVGVVVPVTTVCPCSKEISCMGAHNQRSHVTVKVRFKKFFWLEDIIR
HHCCCCCCCCCCEEEEEEEHHHHCCCCCCCCEEECCCCCCCEEEEEEEEHHHHHHHHHHH
LVETSASGEVYSLLKRVDEKYVTEQGYANPMFVEDVVRNVAERLNENSNLTWYSVEAENF
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
ESIHNHNAYAYVEKE
HHHHCCCEEEEEECC
>Mature Secondary Structure
MIDIQNLEDHRKINIQKVGVKGINYPIVVLDKAKGTQHVNASINMYVDLPHHFKGTHMSR
CCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCEEECCEEEEEEECCCCCCCCHHHH
FIEVLNEFRGEINIRTFHTILEKVRDKLKAESAHMEITFPYFIEKTAPVSGAKSLMDYIC
HHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEHHEEECCCCCCHHHHHHHHHH
AFSGMNAENKKDFLVGVVVPVTTVCPCSKEISCMGAHNQRSHVTVKVRFKKFFWLEDIIR
HHCCCCCCCCCCEEEEEEEHHHHCCCCCCCCEEECCCCCCCEEEEEEEEHHHHHHHHHHH
LVETSASGEVYSLLKRVDEKYVTEQGYANPMFVEDVVRNVAERLNENSNLTWYSVEAENF
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
ESIHNHNAYAYVEKE
HHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA