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The map label for this gene is fbp

Identifier: 85859647

GI number: 85859647

Start: 1875942

End: 1876940

Strand: Direct

Name: fbp

Synonym: SYN_01924

Alternate gene names: 85859647

Gene position: 1875942-1876940 (Clockwise)

Preceding gene: 85859646

Following gene: 85859654

Centisome position: 59.0

GC content: 51.65

Gene sequence:

>999_bases
ATGCCAATAGAGTTCGAACAGACATTTCGCAATTTTTTAATGGAGCATCAGGAAAAGTACAACCGCACCTACCACTTCCT
GATTCTTATGGATTCCATCATCACAGCGGCCCAGCGCATTGAGCTGTATTATCGCACCGGCGCGCTCAAGGGAAATCTTG
GCATGGCGGGCTCAATCAATGTACAGGGCGAAAGCGTCATGAAGATGGATGATATCGCCAATGAAATCGTACTCCACTAT
CTGGCGGCAAGCAATCGCGTAATTCAGGTTGTGAGCGAAGAAAGCGATGACATCGTCGATATGAACAAGGACGGCGGCCG
CTACTTCGTATATTTCGATCCACTCGACGGATCCTCAAATGTTGCCCATGGCCTGCCGGTCGGGTTTCTGTTCGGCATTG
CCAAGCGCAATCTGGACGGCAATATGAAGGGTCCTGAAGATTTTCATCTCCGCGAAGGCAACGATTATATCGCTGCGGGC
ATGTTTGTCATTCCGACGGGCATGTTCACGCTGGCTCTTCGCGATGCGGGCTGCTGGCGCTTCCATGCCGACGAAACGGC
GACGTATGTCAAACCCATGCGCATGACCCTGCCCGACGATCCCAAAAAATGGGAATTATCATTCAATTCGGCCAATACGA
CCGTCTTCAGCGAAAAAGTCCAGAGTTGGATTCAGGTCAATATAAGTAAATACAAGTTTCGTTATATCGGAGCGCTTGCC
GGTGACTTTCACCGGCTGCTCACAAATGGCGGCCTGTTCATGTATCCGGCAATCGTCAAGCATCCCGATCCAAAAGAAAA
CCGGCCCCAGGGAAAACTGCGGCTTCTGTATGAGGCAAATGTCGTGGCTTTTATGTGCCGGGAAGCCGGCGGCGACGCCA
TTGATGAAACCGGGACGCGCATTATGGAAATCAAACCGGCCGGTCATCACCAGCGCACGACGCTGTATGTGGGTTCCAAG
CCCATCATCGATGAACTTGCCTCCCTGTTCAAGAGTTAG

Upstream 100 bases:

>100_bases
TTCTGAAATCGACTTCGCGCCGTTCCCGAAAGCGGCGCATTGAGGTGCGCGGCAGCACAGTTTCTGCAACGATTTTTTAA
CAGTTTTACAGGAGGGTTTT

Downstream 100 bases:

>100_bases
CGCTGCACATTTCTCAAAAGCTGCGGAATTCGTCTGATAATTCAGGCGAATCCTTTTTTTCGGATCGACAGCGACATTCT
TTACGACAGAGGATTTCGGT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPIEFEQTFRNFLMEHQEKYNRTYHFLILMDSIITAAQRIELYYRTGALKGNLGMAGSINVQGESVMKMDDIANEIVLHY
LAASNRVIQVVSEESDDIVDMNKDGGRYFVYFDPLDGSSNVAHGLPVGFLFGIAKRNLDGNMKGPEDFHLREGNDYIAAG
MFVIPTGMFTLALRDAGCWRFHADETATYVKPMRMTLPDDPKKWELSFNSANTTVFSEKVQSWIQVNISKYKFRYIGALA
GDFHRLLTNGGLFMYPAIVKHPDPKENRPQGKLRLLYEANVVAFMCREAGGDAIDETGTRIMEIKPAGHHQRTTLYVGSK
PIIDELASLFKS

Sequences:

>Translated_332_residues
MPIEFEQTFRNFLMEHQEKYNRTYHFLILMDSIITAAQRIELYYRTGALKGNLGMAGSINVQGESVMKMDDIANEIVLHY
LAASNRVIQVVSEESDDIVDMNKDGGRYFVYFDPLDGSSNVAHGLPVGFLFGIAKRNLDGNMKGPEDFHLREGNDYIAAG
MFVIPTGMFTLALRDAGCWRFHADETATYVKPMRMTLPDDPKKWELSFNSANTTVFSEKVQSWIQVNISKYKFRYIGALA
GDFHRLLTNGGLFMYPAIVKHPDPKENRPQGKLRLLYEANVVAFMCREAGGDAIDETGTRIMEIKPAGHHQRTTLYVGSK
PIIDELASLFKS
>Mature_331_residues
PIEFEQTFRNFLMEHQEKYNRTYHFLILMDSIITAAQRIELYYRTGALKGNLGMAGSINVQGESVMKMDDIANEIVLHYL
AASNRVIQVVSEESDDIVDMNKDGGRYFVYFDPLDGSSNVAHGLPVGFLFGIAKRNLDGNMKGPEDFHLREGNDYIAAGM
FVIPTGMFTLALRDAGCWRFHADETATYVKPMRMTLPDDPKKWELSFNSANTTVFSEKVQSWIQVNISKYKFRYIGALAG
DFHRLLTNGGLFMYPAIVKHPDPKENRPQGKLRLLYEANVVAFMCREAGGDAIDETGTRIMEIKPAGHHQRTTLYVGSKP
IIDELASLFKS

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=326, Percent_Identity=30.9815950920245, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI189083692, Length=333, Percent_Identity=30.9309309309309, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI16579888, Length=333, Percent_Identity=30.9309309309309, Blast_Score=146, Evalue=3e-35,
Organism=Escherichia coli, GI1790679, Length=336, Percent_Identity=33.0357142857143, Blast_Score=161, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17508131, Length=330, Percent_Identity=31.5151515151515, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6323409, Length=331, Percent_Identity=30.5135951661631, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI45550998, Length=334, Percent_Identity=31.437125748503, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI19921562, Length=334, Percent_Identity=31.437125748503, Blast_Score=134, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_SYNAS (Q2LUC0)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_461849.1
- HSSP:   P0A993
- ProteinModelPortal:   Q2LUC0
- SMR:   Q2LUC0
- STRING:   Q2LUC0
- GeneID:   3883230
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_01924
- NMPDR:   fig|56780.10.peg.1788
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   YSINEGS
- PhylomeDB:   Q2LUC0
- BioCyc:   SACI56780:SYN_01924-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR000760
- PANTHER:   PTHR11556
- PRINTS:   PR00115
- PRINTS:   PR00377

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 37530; Mature: 37399

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00124 FBPASE

Important sites: BINDING 209-209 BINDING 235-235 BINDING 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIEFEQTFRNFLMEHQEKYNRTYHFLILMDSIITAAQRIELYYRTGALKGNLGMAGSIN
CCCCHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHEEEEEEECCEECCCCCCEEEE
VQGESVMKMDDIANEIVLHYLAASNRVIQVVSEESDDIVDMNKDGGRYFVYFDPLDGSSN
ECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCEEEEEEECCCCCCC
VAHGLPVGFLFGIAKRNLDGNMKGPEDFHLREGNDYIAAGMFVIPTGMFTLALRDAGCWR
CCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEECEEEECCCEEEEEEECCCCEE
FHADETATYVKPMRMTLPDDPKKWELSFNSANTTVFSEKVQSWIQVNISKYKFRYIGALA
EECCCCCCEECCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHEEEHHHEEEEEEHHHH
GDFHRLLTNGGLFMYPAIVKHPDPKENRPQGKLRLLYEANVVAFMCREAGGDAIDETGTR
HHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCEEEEEEECCEEEEEEHHCCCCCCCCCCCE
IMEIKPAGHHQRTTLYVGSKPIIDELASLFKS
EEEECCCCCCCEEEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
PIEFEQTFRNFLMEHQEKYNRTYHFLILMDSIITAAQRIELYYRTGALKGNLGMAGSIN
CCCHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHEEEEEEECCEECCCCCCEEEE
VQGESVMKMDDIANEIVLHYLAASNRVIQVVSEESDDIVDMNKDGGRYFVYFDPLDGSSN
ECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCEEEEEEECCCCCCC
VAHGLPVGFLFGIAKRNLDGNMKGPEDFHLREGNDYIAAGMFVIPTGMFTLALRDAGCWR
CCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEECEEEECCCEEEEEEECCCCEE
FHADETATYVKPMRMTLPDDPKKWELSFNSANTTVFSEKVQSWIQVNISKYKFRYIGALA
EECCCCCCEECCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHEEEHHHEEEEEEHHHH
GDFHRLLTNGGLFMYPAIVKHPDPKENRPQGKLRLLYEANVVAFMCREAGGDAIDETGTR
HHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCEEEEEEECCEEEEEEHHCCCCCCCCCCCE
IMEIKPAGHHQRTTLYVGSKPIIDELASLFKS
EEEECCCCCCCEEEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA