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The map label for this gene is panC [H]

Identifier: 85859080

GI number: 85859080

Start: 1255470

End: 1256348

Strand: Direct

Name: panC [H]

Synonym: SYN_00420

Alternate gene names: 85859080

Gene position: 1255470-1256348 (Clockwise)

Preceding gene: 85859079

Following gene: 85859081

Centisome position: 39.49

GC content: 50.4

Gene sequence:

>879_bases
GTGGGGACTATACGACCGATGAAGATCATTCACGCGGTTCACGAGATGCAGGACTATTCCGAAGCTCTGAGGAAGGCAGG
CAGGAGGATCGCCTTTGTTCCGACGATGGGCTATTTTCACGAAGGTCATCTCGACCTGATGCGTGAAGGCAGAAAAAGAT
CAGACTGTCTGGTCGTCAGCATTTACGTAAACCCGACCCAGTTCGGCGCCAGTGAAGATCTGGAAAAGTATCCACGAAAC
TTCGACCGGGACAGCCAATTGGCGGAAGAAGTCGGCGTGGATGTCATTTTCTTTCCCTCCAATGCCGAAATGTACCCGGT
AAACTACCAGACTTATGTCACTGTGGAAGAAGTGACAAAAAATCTCTGCGGTCTGTCCAGACCGGGACATTTTCGGGGCG
TTGCCACTGTATGCGCCAAACTGTTCAACATGGTTAAACCTCATGCGGCGATCTTCGGTAAAAAAGATTTTCAGCAACTG
GTGACGATAAAACGGATGGTTGCTGATTTGAATATGGATCTTGAAATCGTCGGCATGCCGACAACAAGAGAAAAAGACGG
GCTTGCCATGAGTTCCCGTAATGTTTATCTCAGCCCGGAGGAAAGGGAATCGGCCCTCTGTCTGAGCCGATCACTGCTGA
TGGCACGGGAGCGATATGATCAGGGGGAACGGGATGCCGGGCGGATACTGCAATCGATCAAAGCCTATATCGAAAGCGTT
CCCTCCACGCGAATCGATTATCTGAAAATCTGCAGTACGACGACCATGCAGGATGTTCAGAGCCTGGATCAGGAGTCCGT
TCTGGCGCTTGCCGTATTTGTCGGTTCCACGAGACTTATAGACAATCACGTGTTCGGTGAAGAGCTGAACATCAGATAA

Upstream 100 bases:

>100_bases
TCACCGCTTGGATCCGCTGAAGGACTGAGACGGAAGGCACAGGAAGAACGAAATTTCAAGGGATTATAGCCTCCCCGTCC
AGAATGGGGAGGCTTTTTTT

Downstream 100 bases:

>100_bases
AAAAGAAATCACGACATCGGACAGGAACGCGCTTCTGTGCCGAGGGGAAGGTGAATCCATGCAAAGGTTGATGCTTAAAT
CCAAAATTCACAGAGCGACC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MGTIRPMKIIHAVHEMQDYSEALRKAGRRIAFVPTMGYFHEGHLDLMREGRKRSDCLVVSIYVNPTQFGASEDLEKYPRN
FDRDSQLAEEVGVDVIFFPSNAEMYPVNYQTYVTVEEVTKNLCGLSRPGHFRGVATVCAKLFNMVKPHAAIFGKKDFQQL
VTIKRMVADLNMDLEIVGMPTTREKDGLAMSSRNVYLSPEERESALCLSRSLLMARERYDQGERDAGRILQSIKAYIESV
PSTRIDYLKICSTTTMQDVQSLDQESVLALAVFVGSTRLIDNHVFGEELNIR

Sequences:

>Translated_292_residues
MGTIRPMKIIHAVHEMQDYSEALRKAGRRIAFVPTMGYFHEGHLDLMREGRKRSDCLVVSIYVNPTQFGASEDLEKYPRN
FDRDSQLAEEVGVDVIFFPSNAEMYPVNYQTYVTVEEVTKNLCGLSRPGHFRGVATVCAKLFNMVKPHAAIFGKKDFQQL
VTIKRMVADLNMDLEIVGMPTTREKDGLAMSSRNVYLSPEERESALCLSRSLLMARERYDQGERDAGRILQSIKAYIESV
PSTRIDYLKICSTTTMQDVQSLDQESVLALAVFVGSTRLIDNHVFGEELNIR
>Mature_291_residues
GTIRPMKIIHAVHEMQDYSEALRKAGRRIAFVPTMGYFHEGHLDLMREGRKRSDCLVVSIYVNPTQFGASEDLEKYPRNF
DRDSQLAEEVGVDVIFFPSNAEMYPVNYQTYVTVEEVTKNLCGLSRPGHFRGVATVCAKLFNMVKPHAAIFGKKDFQQLV
TIKRMVADLNMDLEIVGMPTTREKDGLAMSSRNVYLSPEERESALCLSRSLLMARERYDQGERDAGRILQSIKAYIESVP
STRIDYLKICSTTTMQDVQSLDQESVLALAVFVGSTRLIDNHVFGEELNIR

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=280, Percent_Identity=43.5714285714286, Blast_Score=235, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6322046, Length=312, Percent_Identity=37.1794871794872, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 33132; Mature: 33000

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTIRPMKIIHAVHEMQDYSEALRKAGRRIAFVPTMGYFHEGHLDLMREGRKRSDCLVVS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCCCCEEEEE
IYVNPTQFGASEDLEKYPRNFDRDSQLAEEVGVDVIFFPSNAEMYPVNYQTYVTVEEVTK
EEECCHHCCCCHHHHHCCCCCCHHHHHHHHHCCEEEEECCCCEEEECCCEEEEEHHHHHH
NLCGLSRPGHFRGVATVCAKLFNMVKPHAAIFGKKDFQQLVTIKRMVADLNMDLEIVGMP
HHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEECC
TTREKDGLAMSSRNVYLSPEERESALCLSRSLLMARERYDQGERDAGRILQSIKAYIESV
CCCCCCCCEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
PSTRIDYLKICSTTTMQDVQSLDQESVLALAVFVGSTRLIDNHVFGEELNIR
CCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GTIRPMKIIHAVHEMQDYSEALRKAGRRIAFVPTMGYFHEGHLDLMREGRKRSDCLVVS
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCCCCEEEEE
IYVNPTQFGASEDLEKYPRNFDRDSQLAEEVGVDVIFFPSNAEMYPVNYQTYVTVEEVTK
EEECCHHCCCCHHHHHCCCCCCHHHHHHHHHCCEEEEECCCCEEEECCCEEEEEHHHHHH
NLCGLSRPGHFRGVATVCAKLFNMVKPHAAIFGKKDFQQLVTIKRMVADLNMDLEIVGMP
HHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEECC
TTREKDGLAMSSRNVYLSPEERESALCLSRSLLMARERYDQGERDAGRILQSIKAYIESV
CCCCCCCCEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
PSTRIDYLKICSTTTMQDVQSLDQESVLALAVFVGSTRLIDNHVFGEELNIR
CCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA