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The map label for this gene is phoP [H]

Identifier: 85859021

GI number: 85859021

Start: 1200162

End: 1200899

Strand: Direct

Name: phoP [H]

Synonym: SYN_00981

Alternate gene names: 85859021

Gene position: 1200162-1200899 (Clockwise)

Preceding gene: 85859019

Following gene: 85859023

Centisome position: 37.75

GC content: 54.47

Gene sequence:

>738_bases
ATGGAAGGCGGAACAAAGGAGGATTTCATGCCCACAGGACAGAAGCGCATCCTGGTTGTGGATGACGAAAAGGATATCGT
GGAACTCCTGACCTTTAATCTGGAAAAGGAAGGCTTTGCCGTCACGCAGGCTTTCGATGGAGAAGAGGCGTTAAAAACAA
TCCGGACCAATAAGCCGGATCTTGTGATTCTCGATCTGATGCTGCCCGGCGTTTCAGGACTGGATATCTGTCGGCAGGTA
CGCCGCAACGAGGAGACAGAAACCCTTCCTGTTATCATGCTAACTGCGAAAGGCGAGCCGCTGGACAAGGTCGTTGGTCT
GGAAATCGGGGCTGATGATTACATCACCAAACCGTTCAACGTGCGGGAACTGGTGGCGCGGGTGAGAGCCGTGCTGCGCC
GGTCCAGTCAGCGGCCGAAGGAAGCTTCGGAAGGGACATTCACATTTCAGGGGCTTCATGTGGATTATCGAACCTACCAG
GTTTCTGTGGACGGGAAAAAGATTGAACTGGGACCGACGGAGATCAAACTGCTGCGGTGCCTTACCCGCCAGCCCGGGAG
GGTCTTCAGCCGGGATCAGTTGCTCGATGCCGTCTGGGGAGAGGAGGCCTTCGTAGAGCCCAGGACGGTTGATGTCCATA
TCAGCCGCCTGCGAGCGGATATTGAACAGGATAAAGAAAAACCGAAATATATACTGACCGTCCGGGGGATCGGCTACAAA
TTCGCCGATGGTTCCTGA

Upstream 100 bases:

>100_bases
TCAGAGACGAGACCAAGGCGGCAACGCTGAGACGACTAAGTCGTCCACAGGGTGAACTGAATGGAGTCGATAACGAAGAT
ATCGAGGAGAACGCCTCAAT

Downstream 100 bases:

>100_bases
TCCAGGAAATACCCTTCAATTTCTTCTGGCTCCCACAAGGTCCGCGTTAAGCCGCAACCCTTGAACAGTATGGTCACCAG
TTTTCCGTCCCGAGTACCGA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MEGGTKEDFMPTGQKRILVVDDEKDIVELLTFNLEKEGFAVTQAFDGEEALKTIRTNKPDLVILDLMLPGVSGLDICRQV
RRNEETETLPVIMLTAKGEPLDKVVGLEIGADDYITKPFNVRELVARVRAVLRRSSQRPKEASEGTFTFQGLHVDYRTYQ
VSVDGKKIELGPTEIKLLRCLTRQPGRVFSRDQLLDAVWGEEAFVEPRTVDVHISRLRADIEQDKEKPKYILTVRGIGYK
FADGS

Sequences:

>Translated_245_residues
MEGGTKEDFMPTGQKRILVVDDEKDIVELLTFNLEKEGFAVTQAFDGEEALKTIRTNKPDLVILDLMLPGVSGLDICRQV
RRNEETETLPVIMLTAKGEPLDKVVGLEIGADDYITKPFNVRELVARVRAVLRRSSQRPKEASEGTFTFQGLHVDYRTYQ
VSVDGKKIELGPTEIKLLRCLTRQPGRVFSRDQLLDAVWGEEAFVEPRTVDVHISRLRADIEQDKEKPKYILTVRGIGYK
FADGS
>Mature_245_residues
MEGGTKEDFMPTGQKRILVVDDEKDIVELLTFNLEKEGFAVTQAFDGEEALKTIRTNKPDLVILDLMLPGVSGLDICRQV
RRNEETETLPVIMLTAKGEPLDKVVGLEIGADDYITKPFNVRELVARVRAVLRRSSQRPKEASEGTFTFQGLHVDYRTYQ
VSVDGKKIELGPTEIKLLRCLTRQPGRVFSRDQLLDAVWGEEAFVEPRTVDVHISRLRADIEQDKEKPKYILTVRGIGYK
FADGS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=47.8070175438597, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=41.5929203539823, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=42.7350427350427, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=42.1276595744681, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=40.0881057268723, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=36.8888888888889, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=40.1785714285714, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=36.2068965517241, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=37.1681415929204, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=34.9557522123894, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=34.4978165938865, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=33.6283185840708, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=31.8965517241379, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.9059829059829, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788550, Length=127, Percent_Identity=35.4330708661417, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=123, Percent_Identity=34.9593495934959, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27680; Mature: 27680

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGGTKEDFMPTGQKRILVVDDEKDIVELLTFNLEKEGFAVTQAFDGEEALKTIRTNKPD
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCC
LVILDLMLPGVSGLDICRQVRRNEETETLPVIMLTAKGEPLDKVVGLEIGADDYITKPFN
EEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHEEEEEECCCCCCCCCCC
VRELVARVRAVLRRSSQRPKEASEGTFTFQGLHVDYRTYQVSVDGKKIELGPTEIKLLRC
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEEEEECCCEEEECHHHHHHHHH
LTRQPGRVFSRDQLLDAVWGEEAFVEPRTVDVHISRLRADIEQDKEKPKYILTVRGIGYK
HHCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCEEEEEECCCEE
FADGS
ECCCC
>Mature Secondary Structure
MEGGTKEDFMPTGQKRILVVDDEKDIVELLTFNLEKEGFAVTQAFDGEEALKTIRTNKPD
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCC
LVILDLMLPGVSGLDICRQVRRNEETETLPVIMLTAKGEPLDKVVGLEIGADDYITKPFN
EEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHEEEEEECCCCCCCCCCC
VRELVARVRAVLRRSSQRPKEASEGTFTFQGLHVDYRTYQVSVDGKKIELGPTEIKLLRC
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEEEEECCCEEEECHHHHHHHHH
LTRQPGRVFSRDQLLDAVWGEEAFVEPRTVDVHISRLRADIEQDKEKPKYILTVRGIGYK
HHCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCEEEEEECCCEE
FADGS
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]