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The map label for this gene is kamA [H]

Identifier: 85858714

GI number: 85858714

Start: 893762

End: 894781

Strand: Direct

Name: kamA [H]

Synonym: SYN_00182

Alternate gene names: 85858714

Gene position: 893762-894781 (Clockwise)

Preceding gene: 85858712

Following gene: 85858715

Centisome position: 28.11

GC content: 58.82

Gene sequence:

>1020_bases
GTGGACGATGCGGACTGGAAGGACTGGCGATGGCAGGTCAGAAACCGGATACGGTCGGGCAGACAGCTTGCCGAATTGCT
GAAGGAGGCGCCGATTGCGGCCGGATCGTTGCGGGCCGTGATCCGGACTTACCCCTTTTCCATTACGCCTTACTATTTTT
CCCTCATTCGAGAGGGGGATCCCGATGATCCCATCCGGTTTCAGTGCGTTCCCGACCCCCGGGAGGTTTCGTTTTCCCTG
GGGGGAGTGGACGATCCCCTCGAGGAATCCAGGGATATGCCCGTTCCGGGGCTGATCCATCGCTATGCTGATCGCTGCCT
GATCATGGCGACTTCGAAGTGCATGATGTACTGCCGGCATTGCAACCGCAAGCGAAGATGGAAAGCGGGTGCGGCGGACA
GGGCCCCTTTGCGGGCCATGATCGATTATGTAGCCGCGACGCCGGGAATCCGTGAGGTCATTGTTTCCGGGGGCGACCCT
CTGACGCTGCCTGAGAAAGTGCTGGACGAGTTTCTCGGGGCTCTGCGGGCCATTCCCCATGTGGAGGTTCTGCGCATCGG
CAGCCGGATTCCCGTTGTCCTGCCCATGCGGATCACTGTTCCTCTGGTGCGCATTCTGCGGAAGCATCGTCCCTTGTGGT
TCAACACGCAGTTCAACTCCCCCCGGGAGATCACGCCCGAATCCGCTGAGGCCTGTGAACGGCTGGTGGATGCCGGGATT
CCCGTTTCCAACCAGTCGGTACTCCTTAAGGGAATCAACGACGATTATGAGACGATGCGCAGACTTCTGTACGGGTTGCA
GCGTATTTCCGTGCGGCCTTATTATCTGTTTCAGTGTGATCCCGTGCGGGGCGCCGATCATTTCCGGGTCGATTTCTGGA
AGGGCATGGAAATGATGGAGCGGATTTCCCGTCAGACTTCCGGCCTCTGCCTGCCCCGTTATGTCATCGATGTTCCCGGC
GGCAAAGGAAAAATGTCCCTCCAGACCTTCTCCCTGCTCGCTGATTCCGACATATCCTGA

Upstream 100 bases:

>100_bases
TGGAGATGGGGTGTAAAATATTATAAAGAATAAGAAGAAGGTCAAAAGCGCAATCGTCGGTGCGGATATCAATAAGGACG
GACGCGGACCCTGGAAAGAT

Downstream 100 bases:

>100_bases
ACTATCCCGAAGACATAACATTTTTTTGACAAGGGGCTGGAAATGAATTAAGAAGCGGCACATCGTATTCAGGAATAAAA
AGTTGTTAAAAATCCCAAAA

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MDDADWKDWRWQVRNRIRSGRQLAELLKEAPIAAGSLRAVIRTYPFSITPYYFSLIREGDPDDPIRFQCVPDPREVSFSL
GGVDDPLEESRDMPVPGLIHRYADRCLIMATSKCMMYCRHCNRKRRWKAGAADRAPLRAMIDYVAATPGIREVIVSGGDP
LTLPEKVLDEFLGALRAIPHVEVLRIGSRIPVVLPMRITVPLVRILRKHRPLWFNTQFNSPREITPESAEACERLVDAGI
PVSNQSVLLKGINDDYETMRRLLYGLQRISVRPYYLFQCDPVRGADHFRVDFWKGMEMMERISRQTSGLCLPRYVIDVPG
GKGKMSLQTFSLLADSDIS

Sequences:

>Translated_339_residues
MDDADWKDWRWQVRNRIRSGRQLAELLKEAPIAAGSLRAVIRTYPFSITPYYFSLIREGDPDDPIRFQCVPDPREVSFSL
GGVDDPLEESRDMPVPGLIHRYADRCLIMATSKCMMYCRHCNRKRRWKAGAADRAPLRAMIDYVAATPGIREVIVSGGDP
LTLPEKVLDEFLGALRAIPHVEVLRIGSRIPVVLPMRITVPLVRILRKHRPLWFNTQFNSPREITPESAEACERLVDAGI
PVSNQSVLLKGINDDYETMRRLLYGLQRISVRPYYLFQCDPVRGADHFRVDFWKGMEMMERISRQTSGLCLPRYVIDVPG
GKGKMSLQTFSLLADSDIS
>Mature_339_residues
MDDADWKDWRWQVRNRIRSGRQLAELLKEAPIAAGSLRAVIRTYPFSITPYYFSLIREGDPDDPIRFQCVPDPREVSFSL
GGVDDPLEESRDMPVPGLIHRYADRCLIMATSKCMMYCRHCNRKRRWKAGAADRAPLRAMIDYVAATPGIREVIVSGGDP
LTLPEKVLDEFLGALRAIPHVEVLRIGSRIPVVLPMRITVPLVRILRKHRPLWFNTQFNSPREITPESAEACERLVDAGI
PVSNQSVLLKGINDDYETMRRLLYGLQRISVRPYYLFQCDPVRGADHFRVDFWKGMEMMERISRQTSGLCLPRYVIDVPG
GKGKMSLQTFSLLADSDIS

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=326, Percent_Identity=32.5153374233129, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 38720; Mature: 38720

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDADWKDWRWQVRNRIRSGRQLAELLKEAPIAAGSLRAVIRTYPFSITPYYFSLIREGD
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCC
PDDPIRFQCVPDPREVSFSLGGVDDPLEESRDMPVPGLIHRYADRCLIMATSKCMMYCRH
CCCCEEEEECCCHHHCEEECCCCCCCHHHCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHH
CNRKRRWKAGAADRAPLRAMIDYVAATPGIREVIVSGGDPLTLPEKVLDEFLGALRAIPH
CCHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
VEVLRIGSRIPVVLPMRITVPLVRILRKHRPLWFNTQFNSPREITPESAEACERLVDAGI
HHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCC
PVSNQSVLLKGINDDYETMRRLLYGLQRISVRPYYLFQCDPVRGADHFRVDFWKGMEMME
CCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEHHHHHHHHHHH
RISRQTSGLCLPRYVIDVPGGKGKMSLQTFSLLADSDIS
HHHHHHCCCCCCEEEEECCCCCCCEEHHHHHHHHCCCCC
>Mature Secondary Structure
MDDADWKDWRWQVRNRIRSGRQLAELLKEAPIAAGSLRAVIRTYPFSITPYYFSLIREGD
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCC
PDDPIRFQCVPDPREVSFSLGGVDDPLEESRDMPVPGLIHRYADRCLIMATSKCMMYCRH
CCCCEEEEECCCHHHCEEECCCCCCCHHHCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHH
CNRKRRWKAGAADRAPLRAMIDYVAATPGIREVIVSGGDPLTLPEKVLDEFLGALRAIPH
CCHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
VEVLRIGSRIPVVLPMRITVPLVRILRKHRPLWFNTQFNSPREITPESAEACERLVDAGI
HHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCC
PVSNQSVLLKGINDDYETMRRLLYGLQRISVRPYYLFQCDPVRGADHFRVDFWKGMEMME
CCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEHHHHHHHHHHH
RISRQTSGLCLPRYVIDVPGGKGKMSLQTFSLLADSDIS
HHHHHHCCCCCCEEEEECCCCCCCEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]