Click here to switch to the map view.

The map label for this gene is 85858712

Identifier: 85858712

GI number: 85858712

Start: 892478

End: 893332

Strand: Direct

Name: 85858712

Synonym: SYN_00180

Alternate gene names: NA

Gene position: 892478-893332 (Clockwise)

Preceding gene: 85858711

Following gene: 85858714

Centisome position: 28.07

GC content: 51.93

Gene sequence:

>855_bases
ATGGATGAAAGAGAAATTTACAGAATGAAGGAAACATTAAGGTCGGTAACGAAAAAGATGCCTCTTGCGGTGGTTGTCGG
GATCATCATCGCAGTTATCCTTTTTTTCCGTCCCTTCGTTCAGATCGGAGCCGGCGAAAGAGGCGTTGTGCTCAATTTCG
GCGCCGTCCAGGATACGGTCCTGGGTGAAGGCCTCCACTTCAGAATTCCCATCATGCAAACGGTCATTCCCGTGGACGTG
AAGGTACAGAAGTCAGAATCCGAGGCTGCCGCAGCATCGTCGGATCTTCAGGATGTGAGTTCGACGGTCGCACTCAATTA
CCATATCATTCCCGATAAGGCGAATATTGTCTATCAGAGCATCGGTCTTGCATTCAAGGAGAGGATCATAGACCCCGCCG
TTCAAGAAGTGGTTAAAGCCGTCACCGCCAAGTACACCGCAGAGGAGCTTATCACAAAGAGGCCGGCAGTAAGCGACGCC
ATGAAGGCGGCCCTCACGGACAGACTTCTTGCGAATAATATCTCCGTCGATGCCTTCTCCATTGTCGGCTTCAGCTTTTC
CAAAGGATTCATGGAAGCGATCGAAGCAAAGCAGACGGCGGAGCAGCTGGCGCTGAAGGCGAAGAGAGATCTGGAGAGGA
TAAAAATAGAAGCGGATCAGAAGGTTGCCGCGGCAAAAGCGGAGGCGGAAGCCTTAAGGCTGCAGCGGGCCAACATTTCC
GCTGATCTGATCGAGCTCAGAAGGATAGAGGCCAATCTCAAAGCAATAGAGAAATGGAACGGAATCATGCCGCAGGTTAC
CGGGGCGGGAGCTGTCCCGTTCATCGGTTTGGGCGGTTCAGAAAAGACTAAATAG

Upstream 100 bases:

>100_bases
TTGTGCCGCTGAAGGGCAGTTTTAGAGTGGCCGGGCCGCCACCAGGGGGTAATTCTCCGGGGCGGCCTTTTTTTAAATCA
GAAAACGGGGAGGAATTTTA

Downstream 100 bases:

>100_bases
CGGAGTAGATGGGAGAGGGAAGGAAGATCTATCAGGCAGAATACTGCTGATTGATCGGAGTCTGTCTCTTAAAGGACGGG
AATTTGAAGTTCAGGAGACA

Product: HflC protein

Products: NA

Alternate protein names: Prohibitin; SPFH Domain / Band 7 Family Protein; SPFH Domain-Containing Protein/Band 7 Family Protein; SPFH Domain Band 7 Family Protein; Band 7 Family Protein; HflC Protein; Band 7 Protein Like; Spfh Domain Band 7 Family Protein; Prohibitin Family Protein; Band 7 Protein Cation Conductance; Membrane Protease Complex Subunit; Spfh Domain Protein; Membrane Protease Subunit; Prohibitin Protein

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MDEREIYRMKETLRSVTKKMPLAVVVGIIIAVILFFRPFVQIGAGERGVVLNFGAVQDTVLGEGLHFRIPIMQTVIPVDV
KVQKSESEAAAASSDLQDVSSTVALNYHIIPDKANIVYQSIGLAFKERIIDPAVQEVVKAVTAKYTAEELITKRPAVSDA
MKAALTDRLLANNISVDAFSIVGFSFSKGFMEAIEAKQTAEQLALKAKRDLERIKIEADQKVAAAKAEAEALRLQRANIS
ADLIELRRIEANLKAIEKWNGIMPQVTGAGAVPFIGLGGSEKTK

Sequences:

>Translated_284_residues
MDEREIYRMKETLRSVTKKMPLAVVVGIIIAVILFFRPFVQIGAGERGVVLNFGAVQDTVLGEGLHFRIPIMQTVIPVDV
KVQKSESEAAAASSDLQDVSSTVALNYHIIPDKANIVYQSIGLAFKERIIDPAVQEVVKAVTAKYTAEELITKRPAVSDA
MKAALTDRLLANNISVDAFSIVGFSFSKGFMEAIEAKQTAEQLALKAKRDLERIKIEADQKVAAAKAEAEALRLQRANIS
ADLIELRRIEANLKAIEKWNGIMPQVTGAGAVPFIGLGGSEKTK
>Mature_284_residues
MDEREIYRMKETLRSVTKKMPLAVVVGIIIAVILFFRPFVQIGAGERGVVLNFGAVQDTVLGEGLHFRIPIMQTVIPVDV
KVQKSESEAAAASSDLQDVSSTVALNYHIIPDKANIVYQSIGLAFKERIIDPAVQEVVKAVTAKYTAEELITKRPAVSDA
MKAALTDRLLANNISVDAFSIVGFSFSKGFMEAIEAKQTAEQLALKAKRDLERIKIEADQKVAAAKAEAEALRLQRANIS
ADLIELRRIEANLKAIEKWNGIMPQVTGAGAVPFIGLGGSEKTK

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6005854, Length=214, Percent_Identity=36.9158878504673, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI221307584, Length=214, Percent_Identity=36.9158878504673, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI4505773, Length=236, Percent_Identity=32.2033898305085, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193205005, Length=213, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17509869, Length=232, Percent_Identity=34.051724137931, Blast_Score=113, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6321571, Length=235, Percent_Identity=31.063829787234, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321670, Length=214, Percent_Identity=32.2429906542056, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24585145, Length=212, Percent_Identity=34.9056603773585, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24585147, Length=212, Percent_Identity=34.9056603773585, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI161077244, Length=196, Percent_Identity=34.6938775510204, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI161077238, Length=196, Percent_Identity=34.6938775510204, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI161077236, Length=196, Percent_Identity=34.6938775510204, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI161077234, Length=196, Percent_Identity=34.6938775510204, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI161077242, Length=196, Percent_Identity=34.6938775510204, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI161077240, Length=196, Percent_Identity=34.6938775510204, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281365192, Length=238, Percent_Identity=29.4117647058824, Blast_Score=88, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30918; Mature: 30918

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEREIYRMKETLRSVTKKMPLAVVVGIIIAVILFFRPFVQIGAGERGVVLNFGAVQDTV
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHH
LGEGLHFRIPIMQTVIPVDVKVQKSESEAAAASSDLQDVSSTVALNYHIIPDKANIVYQS
HCCCCEEEECHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHH
IGLAFKERIIDPAVQEVVKAVTAKYTAEELITKRPAVSDAMKAALTDRLLANNISVDAFS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHH
IVGFSFSKGFMEAIEAKQTAEQLALKAKRDLERIKIEADQKVAAAKAEAEALRLQRANIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
ADLIELRRIEANLKAIEKWNGIMPQVTGAGAVPFIGLGGSEKTK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MDEREIYRMKETLRSVTKKMPLAVVVGIIIAVILFFRPFVQIGAGERGVVLNFGAVQDTV
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHH
LGEGLHFRIPIMQTVIPVDVKVQKSESEAAAASSDLQDVSSTVALNYHIIPDKANIVYQS
HCCCCEEEECHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHH
IGLAFKERIIDPAVQEVVKAVTAKYTAEELITKRPAVSDAMKAALTDRLLANNISVDAFS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHH
IVGFSFSKGFMEAIEAKQTAEQLALKAKRDLERIKIEADQKVAAAKAEAEALRLQRANIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
ADLIELRRIEANLKAIEKWNGIMPQVTGAGAVPFIGLGGSEKTK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA