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The map label for this gene is helY [H]

Identifier: 85858541

GI number: 85858541

Start: 699671

End: 701773

Strand: Direct

Name: helY [H]

Synonym: SYN_00427

Alternate gene names: 85858541

Gene position: 699671-701773 (Clockwise)

Preceding gene: 85858539

Following gene: 85858542

Centisome position: 22.01

GC content: 52.16

Gene sequence:

>2103_bases
ATGGAGAGTAGCAACACGGCTCATCAGCAAAAAACAAAATGGGGAAACAAACGGTTTTCTTCGGACAGGGAGACAGGGAC
AAAACAGGGAAGAGAAAGGCGCAGACGTACCGCTCGTTCGGCGCGTATGCATCCGGCGATAGAACCTGTTTTGAAAGGCG
TTTTCAAACGGATCGGCAAGCCGCCGGAAAGCGGTTTTGTTCCCGATGAATTTCAGCTTCAAGCCCTGGAAGCGATCAAA
AAAAACGATTGCCTCGTTATGGCGCCCACAGGGTCAGGAAAGACCTGGATCGCGGAACAGGCGATTCTTTCTGTATTCAG
AGCCGGAGGGCGGTGCTGGTACGCTTCGCCCTTGAAGGCGCTGAGCAATGCCAAATGGGTGGAATTCAGTCAGAACTTCG
GCGCTCAGCATGTGGGAATCCTTACGGGAGATACGAAGGAGAATCCGGATGCGCCCATCATCGTCGGGACGACGGAGATA
CTGAGGAATCAGCTTTACGATGTGATGAAGGAAGGGGAAAACCTGCGCTGTGACCTGGTGATCCTGGATGAAGCCCATTA
TCTGGGAGATCGGGACCGCGGGGTGGTCTGGGAAGAAATCATGATCTATCTTCCTGTAAGGGTGAACCTGTTACTTCTTT
CCGCGACAATCGGAAACGGAGACGAAATCGCTGCCTGGTTGTCTTCCCATCGCAACAAGAACTGCACCGTGATCCGGGAA
GAGAAGAGGCCCGTACCCCTTTTCCCTCTTTTTCTTCATCCCTCTGGGCGGATTATGCCACTCATGGAAAATCGGAAACT
GTACGGAAAGGTCGCGGAATACATCGTGGCAAGAAAGACGCGTCGGTCGGGCAGTTTTGCATCCCTGCACTTTGGGGAGA
TCATCAACCTGATGGAGGGATACGCACTGCTGCCTGCCATCTTTTTTCTGAAATCGCGCGCGGAGTGCGATGCCGCGCTG
AAGTCCTGTGCAGGACTTGCTGAAAGGTGTGCGGATGAGCGTTTTTATTATGATCTTGAAGAACTTCTCAGTCGTTTTCC
TTTTCTCCGACAGCACCGGCAGCTATCATTCCTCATTGATTATCGAGTTGCCTCGCACCATGGTGGGCAACTGCCGGCCT
GGAAGTTTTTCGTGGAAAACATGATGAAAAAGGGCCACCTGAGGGCCATTTTTGCAACCTCCACTGTAGCGGCGGGCGTA
AATTATCCCGCCCGGACGATTGTTCTTTTTAATTCGGATCTCTTCAACGGTCATGAATTCTGTCCCATGAGCGGAACGGA
GTTCCACCAGATGACCGGCAGGGCGGGGCGGAGGGGGTTGGATAACATCGGCTTCATGCTGGCCGTTCCGGGGCGTTTTA
TGGATCTGAGTCACATCAGGAAAAGTCTTTTTCAGCCTCCCGATGAAATTCTCAGTCAAATTCGGAGTGATTTTTCCATG
GTGCTGAATCTTCTGCTGTCTCAGACCCCTGAAACGATCCGCGATATTTTCGAGAAATCACTGGCTTCCTATCAACATCA
GAATCTCAATCTGTGGAAGGAATTCTTGAGACATCTTGAATTCCTGAAAGCCGAAGGATTCGTGGATGATCAGGACCGGT
TGACTGAAAACGGCATCTGGGCTTCAAAATTGCGACTTGACCAGCCCCTGTTGATTGCTGAAGGGCTGCGGGCCGGGGGA
TTTCCTTCAGCGGATGAAAAACTGCTGGCCGCTCTGATCGCGCCCTTCGTGAATGATCATGACCAGGAAATCCTGATGGA
TAAGCGTTTTATATCCCGAAAGCTCCGCCGGGCCTTCACACGTCTTGTTACGATGCTGGGACCTTTAACGGAACGCATGA
AGGCCGCCGGTTTTCCTGTCCAACCCCTTTATTTCTGGACAAGCGCGGTGGTTTATGAGTGGGCTTCAGGGGAAGATTGG
GATGAAATCATCAAGAGAACCGGCATAGCTGATGGTGAACTATCCATGCTGGTTCTTCGAGTCGCGGATAATCTGCGACA
GATTGTTTCACTCCGGGATACACACCCTGAAATGGCCCACCTGGCCGCACGGGCGCGGGATGCCATTCTGCGCGAACCCG
TTGTTTTTGAATGGGAGGGGTGA

Upstream 100 bases:

>100_bases
CCGATCCGTGGTACTGAATTTTAAACAAATCAAGGGGCTCGTCCAGTTTAAACGAAGGCAAAAGGTGTCGAGACGACCCG
AAAGGTAAATTGAATATACA

Downstream 100 bases:

>100_bases
TTGCATGAGCGTTTTCGGCGAAGAAAATGCAATAAGCCTATAATTGAAGCTTGACATATTCATCTGGATCAGGGTATAAG
GCCAAATTCGCATATGAGAA

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 700

Protein sequence:

>700_residues
MESSNTAHQQKTKWGNKRFSSDRETGTKQGRERRRRTARSARMHPAIEPVLKGVFKRIGKPPESGFVPDEFQLQALEAIK
KNDCLVMAPTGSGKTWIAEQAILSVFRAGGRCWYASPLKALSNAKWVEFSQNFGAQHVGILTGDTKENPDAPIIVGTTEI
LRNQLYDVMKEGENLRCDLVILDEAHYLGDRDRGVVWEEIMIYLPVRVNLLLLSATIGNGDEIAAWLSSHRNKNCTVIRE
EKRPVPLFPLFLHPSGRIMPLMENRKLYGKVAEYIVARKTRRSGSFASLHFGEIINLMEGYALLPAIFFLKSRAECDAAL
KSCAGLAERCADERFYYDLEELLSRFPFLRQHRQLSFLIDYRVASHHGGQLPAWKFFVENMMKKGHLRAIFATSTVAAGV
NYPARTIVLFNSDLFNGHEFCPMSGTEFHQMTGRAGRRGLDNIGFMLAVPGRFMDLSHIRKSLFQPPDEILSQIRSDFSM
VLNLLLSQTPETIRDIFEKSLASYQHQNLNLWKEFLRHLEFLKAEGFVDDQDRLTENGIWASKLRLDQPLLIAEGLRAGG
FPSADEKLLAALIAPFVNDHDQEILMDKRFISRKLRRAFTRLVTMLGPLTERMKAAGFPVQPLYFWTSAVVYEWASGEDW
DEIIKRTGIADGELSMLVLRVADNLRQIVSLRDTHPEMAHLAARARDAILREPVVFEWEG

Sequences:

>Translated_700_residues
MESSNTAHQQKTKWGNKRFSSDRETGTKQGRERRRRTARSARMHPAIEPVLKGVFKRIGKPPESGFVPDEFQLQALEAIK
KNDCLVMAPTGSGKTWIAEQAILSVFRAGGRCWYASPLKALSNAKWVEFSQNFGAQHVGILTGDTKENPDAPIIVGTTEI
LRNQLYDVMKEGENLRCDLVILDEAHYLGDRDRGVVWEEIMIYLPVRVNLLLLSATIGNGDEIAAWLSSHRNKNCTVIRE
EKRPVPLFPLFLHPSGRIMPLMENRKLYGKVAEYIVARKTRRSGSFASLHFGEIINLMEGYALLPAIFFLKSRAECDAAL
KSCAGLAERCADERFYYDLEELLSRFPFLRQHRQLSFLIDYRVASHHGGQLPAWKFFVENMMKKGHLRAIFATSTVAAGV
NYPARTIVLFNSDLFNGHEFCPMSGTEFHQMTGRAGRRGLDNIGFMLAVPGRFMDLSHIRKSLFQPPDEILSQIRSDFSM
VLNLLLSQTPETIRDIFEKSLASYQHQNLNLWKEFLRHLEFLKAEGFVDDQDRLTENGIWASKLRLDQPLLIAEGLRAGG
FPSADEKLLAALIAPFVNDHDQEILMDKRFISRKLRRAFTRLVTMLGPLTERMKAAGFPVQPLYFWTSAVVYEWASGEDW
DEIIKRTGIADGELSMLVLRVADNLRQIVSLRDTHPEMAHLAARARDAILREPVVFEWEG
>Mature_700_residues
MESSNTAHQQKTKWGNKRFSSDRETGTKQGRERRRRTARSARMHPAIEPVLKGVFKRIGKPPESGFVPDEFQLQALEAIK
KNDCLVMAPTGSGKTWIAEQAILSVFRAGGRCWYASPLKALSNAKWVEFSQNFGAQHVGILTGDTKENPDAPIIVGTTEI
LRNQLYDVMKEGENLRCDLVILDEAHYLGDRDRGVVWEEIMIYLPVRVNLLLLSATIGNGDEIAAWLSSHRNKNCTVIRE
EKRPVPLFPLFLHPSGRIMPLMENRKLYGKVAEYIVARKTRRSGSFASLHFGEIINLMEGYALLPAIFFLKSRAECDAAL
KSCAGLAERCADERFYYDLEELLSRFPFLRQHRQLSFLIDYRVASHHGGQLPAWKFFVENMMKKGHLRAIFATSTVAAGV
NYPARTIVLFNSDLFNGHEFCPMSGTEFHQMTGRAGRRGLDNIGFMLAVPGRFMDLSHIRKSLFQPPDEILSQIRSDFSM
VLNLLLSQTPETIRDIFEKSLASYQHQNLNLWKEFLRHLEFLKAEGFVDDQDRLTENGIWASKLRLDQPLLIAEGLRAGG
FPSADEKLLAALIAPFVNDHDQEILMDKRFISRKLRRAFTRLVTMLGPLTERMKAAGFPVQPLYFWTSAVVYEWASGEDW
DEIIKRTGIADGELSMLVLRVADNLRQIVSLRDTHPEMAHLAARARDAILREPVVFEWEG

Specific function: Unknown

COG id: COG4581

COG function: function code L; Superfamily II RNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI67782311, Length=475, Percent_Identity=36, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI193211480, Length=479, Percent_Identity=34.6555323590814, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI40217847, Length=430, Percent_Identity=26.2790697674419, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI169218225, Length=430, Percent_Identity=25.8139534883721, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI76880486, Length=406, Percent_Identity=25.1231527093596, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI149274648, Length=328, Percent_Identity=25.609756097561, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI222831595, Length=205, Percent_Identity=28.2926829268293, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17542826, Length=457, Percent_Identity=32.1663019693654, Blast_Score=205, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI133930973, Length=493, Percent_Identity=31.237322515213, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17537127, Length=403, Percent_Identity=27.0471464019851, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17537519, Length=427, Percent_Identity=26.2295081967213, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17552356, Length=179, Percent_Identity=29.0502793296089, Blast_Score=77, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322411, Length=466, Percent_Identity=32.8326180257511, Blast_Score=210, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6323430, Length=186, Percent_Identity=45.1612903225806, Blast_Score=157, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6321710, Length=387, Percent_Identity=24.2894056847545, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864608, Length=475, Percent_Identity=33.6842105263158, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI17933658, Length=472, Percent_Identity=31.9915254237288, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17933644, Length=386, Percent_Identity=26.9430051813472, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28574898, Length=393, Percent_Identity=25.6997455470738, Blast_Score=88, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR012961
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF08148 DSHCT; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 79596; Mature: 79596

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSNTAHQQKTKWGNKRFSSDRETGTKQGRERRRRTARSARMHPAIEPVLKGVFKRIGK
CCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PPESGFVPDEFQLQALEAIKKNDCLVMAPTGSGKTWIAEQAILSVFRAGGRCWYASPLKA
CCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCHHHH
LSNAKWVEFSQNFGAQHVGILTGDTKENPDAPIIVGTTEILRNQLYDVMKEGENLRCDLV
HCCCCEEEEHHCCCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCEEEEE
ILDEAHYLGDRDRGVVWEEIMIYLPVRVNLLLLSATIGNGDEIAAWLSSHRNKNCTVIRE
EEECHHHCCCCCCCHHHHHHHHHHCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEC
EKRPVPLFPLFLHPSGRIMPLMENRKLYGKVAEYIVARKTRRSGSFASLHFGEIINLMEG
CCCCCCEEEEEECCCCCEEEHHHCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
YALLPAIFFLKSRAECDAALKSCAGLAERCADERFYYDLEELLSRFPFLRQHRQLSFLID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHEE
YRVASHHGGQLPAWKFFVENMMKKGHLRAIFATSTVAAGVNYPARTIVLFNSDLFNGHEF
EEHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCEEEEEEECCCCCCCCC
CPMSGTEFHQMTGRAGRRGLDNIGFMLAVPGRFMDLSHIRKSLFQPPDEILSQIRSDFSM
CCCCCCHHHHHHCHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VLNLLLSQTPETIRDIFEKSLASYQHQNLNLWKEFLRHLEFLKAEGFVDDQDRLTENGIW
HHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
ASKLRLDQPLLIAEGLRAGGFPSADEKLLAALIAPFVNDHDQEILMDKRFISRKLRRAFT
HHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RLVTMLGPLTERMKAAGFPVQPLYFWTSAVVYEWASGEDWDEIIKRTGIADGELSMLVLR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHCCCCCCHHHHHHHH
VADNLRQIVSLRDTHPEMAHLAARARDAILREPVVFEWEG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MESSNTAHQQKTKWGNKRFSSDRETGTKQGRERRRRTARSARMHPAIEPVLKGVFKRIGK
CCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PPESGFVPDEFQLQALEAIKKNDCLVMAPTGSGKTWIAEQAILSVFRAGGRCWYASPLKA
CCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCHHHH
LSNAKWVEFSQNFGAQHVGILTGDTKENPDAPIIVGTTEILRNQLYDVMKEGENLRCDLV
HCCCCEEEEHHCCCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCEEEEE
ILDEAHYLGDRDRGVVWEEIMIYLPVRVNLLLLSATIGNGDEIAAWLSSHRNKNCTVIRE
EEECHHHCCCCCCCHHHHHHHHHHCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEC
EKRPVPLFPLFLHPSGRIMPLMENRKLYGKVAEYIVARKTRRSGSFASLHFGEIINLMEG
CCCCCCEEEEEECCCCCEEEHHHCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
YALLPAIFFLKSRAECDAALKSCAGLAERCADERFYYDLEELLSRFPFLRQHRQLSFLID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHEE
YRVASHHGGQLPAWKFFVENMMKKGHLRAIFATSTVAAGVNYPARTIVLFNSDLFNGHEF
EEHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCEEEEEEECCCCCCCCC
CPMSGTEFHQMTGRAGRRGLDNIGFMLAVPGRFMDLSHIRKSLFQPPDEILSQIRSDFSM
CCCCCCHHHHHHCHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VLNLLLSQTPETIRDIFEKSLASYQHQNLNLWKEFLRHLEFLKAEGFVDDQDRLTENGIW
HHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
ASKLRLDQPLLIAEGLRAGGFPSADEKLLAALIAPFVNDHDQEILMDKRFISRKLRRAFT
HHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RLVTMLGPLTERMKAAGFPVQPLYFWTSAVVYEWASGEDWDEIIKRTGIADGELSMLVLR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHCCCCCCHHHHHHHH
VADNLRQIVSLRDTHPEMAHLAARARDAILREPVVFEWEG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]