| Definition | Syntrophus aciditrophicus SB chromosome, complete genome. |
|---|---|
| Accession | NC_007759 |
| Length | 3,179,300 |
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The map label for this gene is murF [H]
Identifier: 85858522
GI number: 85858522
Start: 674333
End: 675760
Strand: Direct
Name: murF [H]
Synonym: SYN_01742
Alternate gene names: 85858522
Gene position: 674333-675760 (Clockwise)
Preceding gene: 85858521
Following gene: 85858523
Centisome position: 21.21
GC content: 53.5
Gene sequence:
>1428_bases TTGGACCATAATTCAACACCACAATTTTCTGTTGACGAGCTGCTTGAGGCGGTGGGGGGAACGCTTTTGCAGGGGAGCAC GGATTCCATCATCCGTGGTGTATCAACCGATACCCGACAGCTTGTTGCAGGCAATCTCTATATTCCCCTGAAGGGAGCGA ATTTTGACGGGCATGATTTTCTGGATGTCGCTGTCAAGAAAGGTGCTGGTGGAGTGCTTGTGGATGTCCATCATGCCTTT ATTCTGGAGACGGGTTCAAAAAAGACCGACGGCTGCCTTAAGATTCTCGTGGACGATACTCTGAAGGCTCTGGGGGATCT GGCCCGTTTCTGGCGGAGAGCGGTTGGGCGGCCGGTGATAGCCATCACCGGGAGTTCAGGCAAGACAACGACGAAAGAAA TGACCGCCGCGATCCTTGAACAGACTTTTTCCGTGCTCAAAACGGAGGGAAATCTGAACAATCTGATCGGATTGCCGTTG ACCCTGCTGCGTATGCATCGAGGGCACGATCTGGCCCTTGTGGAGTTGGGCACCAATGCCAGGGGTGAAATCAAACGGTT GACAGAAATCGCGGAACCTGATATCGGGCTCGTTACCAATATCGGCCCGGCCCATCTGGAAGGACTGAAGACCCTGGAGA TCATCAGGGAGGAAAAAGGGGATCTCTACGGCACCATGCCAAAGTCCGGTCTGGCCGTATTTAATGCGGACGATGAGGCC ATGGCCCCTTTGAGGCGGTCTTGGCAGGGTAAAATGTTGACATACGGGATAACATCCCGGGCTGATATGACTGCATCTGA TATTGCGAAGTGGGGTGAATCGGGGCAGTCTTTTACTTTGAATGCCGGCTCCGAGTCCACTGTGGTCCACCTGTCTGCAT TCGGCATGCATAACATTTACAATGCCCTGGCCGCGGCTGCGCTGTCCAGGGCTGCCGGTATCGGCATTAATGAAATTTCC CAAGGTCTCCGGAACTTCCATCCTGTAGCTGCTCGTTTTGAAGTCCACTTCCTGCCGAATGGCGCTTTTCTCGTTGACGA TACCTATAATGCCAATCCGGCATCCGTTCGTGAAGCTCTGAAAACGATCCAGACTTTGAAGGGAAACCATCGCAGTGTGG TTGTTCTCGCCGATATGCTGGAGCTTGGCGACCAGGCGGAGCGGCTTCATGAAACCGTTGGGAGCGAGGCCGCCGCAACT GATGTGGACCGCCTTTTTCTGAAAGGCTCCCTTTCCCGGTCGACGGCTGCCGGGGCGATCAAAGGCGGCATGACGGAAGA GCGGATTCTTTTTTTTGAAGACCCTGAAGAGATTCTCGATGACGTCCTCTCCTTCGTCGAAGCGGGGGACTGGATCCTTG TCAAAGGATCGCGGCTGATGAAAATGGAAGAAATCGTCAAGAAAATTCTTGATCGGACTCCGGCATAA
Upstream 100 bases:
>100_bases ATCATCGCTGATCTGGAATTAAAAGAATTGCCTGCTTGGGCATGTAAAGTCTTCAAAAAGCCAAAGAGAAAAATCGTCGA TCCGGGGCGGGGAGGTTTTT
Downstream 100 bases:
>100_bases ACGGATTGAAACAGAATGCTTTATCACCTTCTCTATCCACTGCATACAACCTATTCCTATTTTAATGTCTTCCGCTACAT CACGTTCCGGACGATATATG
Product: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase
Products: NA
Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]
Number of amino acids: Translated: 475; Mature: 475
Protein sequence:
>475_residues MDHNSTPQFSVDELLEAVGGTLLQGSTDSIIRGVSTDTRQLVAGNLYIPLKGANFDGHDFLDVAVKKGAGGVLVDVHHAF ILETGSKKTDGCLKILVDDTLKALGDLARFWRRAVGRPVIAITGSSGKTTTKEMTAAILEQTFSVLKTEGNLNNLIGLPL TLLRMHRGHDLALVELGTNARGEIKRLTEIAEPDIGLVTNIGPAHLEGLKTLEIIREEKGDLYGTMPKSGLAVFNADDEA MAPLRRSWQGKMLTYGITSRADMTASDIAKWGESGQSFTLNAGSESTVVHLSAFGMHNIYNALAAAALSRAAGIGINEIS QGLRNFHPVAARFEVHFLPNGAFLVDDTYNANPASVREALKTIQTLKGNHRSVVVLADMLELGDQAERLHETVGSEAAAT DVDRLFLKGSLSRSTAAGAIKGGMTEERILFFEDPEEILDDVLSFVEAGDWILVKGSRLMKMEEIVKKILDRTPA
Sequences:
>Translated_475_residues MDHNSTPQFSVDELLEAVGGTLLQGSTDSIIRGVSTDTRQLVAGNLYIPLKGANFDGHDFLDVAVKKGAGGVLVDVHHAF ILETGSKKTDGCLKILVDDTLKALGDLARFWRRAVGRPVIAITGSSGKTTTKEMTAAILEQTFSVLKTEGNLNNLIGLPL TLLRMHRGHDLALVELGTNARGEIKRLTEIAEPDIGLVTNIGPAHLEGLKTLEIIREEKGDLYGTMPKSGLAVFNADDEA MAPLRRSWQGKMLTYGITSRADMTASDIAKWGESGQSFTLNAGSESTVVHLSAFGMHNIYNALAAAALSRAAGIGINEIS QGLRNFHPVAARFEVHFLPNGAFLVDDTYNANPASVREALKTIQTLKGNHRSVVVLADMLELGDQAERLHETVGSEAAAT DVDRLFLKGSLSRSTAAGAIKGGMTEERILFFEDPEEILDDVLSFVEAGDWILVKGSRLMKMEEIVKKILDRTPA >Mature_475_residues MDHNSTPQFSVDELLEAVGGTLLQGSTDSIIRGVSTDTRQLVAGNLYIPLKGANFDGHDFLDVAVKKGAGGVLVDVHHAF ILETGSKKTDGCLKILVDDTLKALGDLARFWRRAVGRPVIAITGSSGKTTTKEMTAAILEQTFSVLKTEGNLNNLIGLPL TLLRMHRGHDLALVELGTNARGEIKRLTEIAEPDIGLVTNIGPAHLEGLKTLEIIREEKGDLYGTMPKSGLAVFNADDEA MAPLRRSWQGKMLTYGITSRADMTASDIAKWGESGQSFTLNAGSESTVVHLSAFGMHNIYNALAAAALSRAAGIGINEIS QGLRNFHPVAARFEVHFLPNGAFLVDDTYNANPASVREALKTIQTLKGNHRSVVVLADMLELGDQAERLHETVGSEAAAT DVDRLFLKGSLSRSTAAGAIKGGMTEERILFFEDPEEILDDVLSFVEAGDWILVKGSRLMKMEEIVKKILDRTPA
Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]
COG id: COG0770
COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786274, Length=461, Percent_Identity=38.6117136659436, Blast_Score=233, Evalue=2e-62,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005863 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.10 [H]
Molecular weight: Translated: 51180; Mature: 51180
Theoretical pI: Translated: 5.62; Mature: 5.62
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDHNSTPQFSVDELLEAVGGTLLQGSTDSIIRGVSTDTRQLVAGNLYIPLKGANFDGHDF CCCCCCCCCCHHHHHHHHCCEEECCCHHHHHHCCCCCCHHHEECCEEEEEECCCCCCCHH LDVAVKKGAGGVLVDVHHAFILETGSKKTDGCLKILVDDTLKALGDLARFWRRAVGRPVI HHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEE AITGSSGKTTTKEMTAAILEQTFSVLKTEGNLNNLIGLPLTLLRMHRGHDLALVELGTNA EEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC RGEIKRLTEIAEPDIGLVTNIGPAHLEGLKTLEIIREEKGDLYGTMPKSGLAVFNADDEA CHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCHHH MAPLRRSWQGKMLTYGITSRADMTASDIAKWGESGQSFTLNAGSESTVVHLSAFGMHNIY HHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEEHHHHHHHH NALAAAALSRAAGIGINEISQGLRNFHPVAARFEVHFLPNGAFLVDDTYNANPASVREAL HHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEEECCCEEEEECCCCCCHHHHHHHH KTIQTLKGNHRSVVVLADMLELGDQAERLHETVGSEAAATDVDRLFLKGSLSRSTAAGAI HHHHHHCCCCCEEEEEHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHH KGGMTEERILFFEDPEEILDDVLSFVEAGDWILVKGSRLMKMEEIVKKILDRTPA CCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MDHNSTPQFSVDELLEAVGGTLLQGSTDSIIRGVSTDTRQLVAGNLYIPLKGANFDGHDF CCCCCCCCCCHHHHHHHHCCEEECCCHHHHHHCCCCCCHHHEECCEEEEEECCCCCCCHH LDVAVKKGAGGVLVDVHHAFILETGSKKTDGCLKILVDDTLKALGDLARFWRRAVGRPVI HHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEE AITGSSGKTTTKEMTAAILEQTFSVLKTEGNLNNLIGLPLTLLRMHRGHDLALVELGTNA EEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC RGEIKRLTEIAEPDIGLVTNIGPAHLEGLKTLEIIREEKGDLYGTMPKSGLAVFNADDEA CHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCHHH MAPLRRSWQGKMLTYGITSRADMTASDIAKWGESGQSFTLNAGSESTVVHLSAFGMHNIY HHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEEHHHHHHHH NALAAAALSRAAGIGINEISQGLRNFHPVAARFEVHFLPNGAFLVDDTYNANPASVREAL HHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEEECCCEEEEECCCCCCHHHHHHHH KTIQTLKGNHRSVVVLADMLELGDQAERLHETVGSEAAATDVDRLFLKGSLSRSTAAGAI HHHHHHCCCCCEEEEEHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHH KGGMTEERILFFEDPEEILDDVLSFVEAGDWILVKGSRLMKMEEIVKKILDRTPA CCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]