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The map label for this gene is spoVD [H]

Identifier: 85858519

GI number: 85858519

Start: 670537

End: 672540

Strand: Direct

Name: spoVD [H]

Synonym: SYN_01739

Alternate gene names: 85858519

Gene position: 670537-672540 (Clockwise)

Preceding gene: 85858518

Following gene: 85858520

Centisome position: 21.09

GC content: 47.95

Gene sequence:

>2004_bases
ATGAGCACGGAATCGAAAAAATGGCTGAAATTTCGACTGATGACGTTATTGGTCTTTTTTGTGATTTTATTTGTCGCTCT
TTTTTCACGGGCTCTTCATCTTCAGATTCTGTCCGGGGAAACGTTAAAGATTCTCGCAGAAAAGCAGCATACCAAAACCC
TGCTCCTTCCGCCTGAGCGCGGGATCATCTTTGATCGGAATGGGGAAAAAATTGCGGCGAGCCTGCAGGTTGATTCAGTC
TGTGCCGATCCCTCAAAAATGGCCCGTCCCGCTGACGCAGCGGAAAGAATTACATCGCTTCTTAACATTGATCGGCAGGT
AGTGATGAAAAAACTTCTGCATTCAAAAAATTTCTGCTGGATTGCCCGCAGAATTCCGCCGGAGCTTGCTCAGAAAGTTG
AGGAAGCGAAAATCGAAGGAGTTTTTCTTGTCAAGGAGCCGAAGAGATTTTACCCGAATGGAGATCTTGCTGGCCAGTTG
GTTGGTCTTGTAGGGTTGGATTCCGTCGGGCTGGAGGGGTTGGAGATCAAGTATGATCAGTACCTTAAGGGCACTCCGGA
AAAATTGATCTGGACTAGGGATGCGAAGGGAAGAATCCTATATCACCGGGCTGAAAAAGCTTCTGTGTCTTCCGATGAAA
GTATCAATATGATTCTTACAATAGACAGTCGAATCCAGTATCTTGTTGAATCCCAACTCAAAGCCGCCGTTCAGGAAAAA
GGGGCCAAAGGCGGACTGGCGATTGTGATGGATCCCAAAACCGGTGAAATTCTCGCATTGGCCAATTCTCCAAGTTTTGA
CCCCAATGTATTACTGAGCGTATCTTCCAATAATAAGAAAAATAAAGTAATTACCGATTGTTTTGATCCCGGATCCACGT
TCAAGCCTTTCCTCGTTGCCGCCGCCCTTGAAGAGGGAACTGTCCGGGAAAATGATCGCTTCTATTGCGAAAATGGATCT
TATACCATTGCCAACCGGGTTATTCATGAAGCCAACCGTAAGCGTCACGGCGCTTTGACGGTTCATGACATTCTTAAATA
TTCCAGTAATATCGGCTCAGTTAAAATAGCCGAAAAGCTGGGCAAAGAAAAATTTTATGAGTATATCCGGGCTTTCGGCT
TCGGAGCTAAGACAGGAATCGATCTGCCCGGGGAAATTCCTGGCTTGCTGCGTCCCGTGGATAACTGGACGCGGGTGGAT
GCGGCAACCATCGCTTTCGGGCAGGGGGTTTCGGTTACAGCCATTCAAATGATTACTGCTCTTTCCACGATTGCCAATCA
GGGGACGATGATGAAACCGTATGTTGTCAAAGCCCTTGTGGACAAAAAAGGGCAGATTGTCCACAATTATTCCCCAACTG
CTGTAAGGCAGGTCATTTCCCCGGACACAGCCAGGCGTCTTACCGCGATTATGACGGATGTGGTCGGACAGGAAGATGGC
ACTGGAAAAAACGCCCGGATTGAAAATGTCTCTGTTGCTGGAAAAACGGGAACCGCACAGAAGTTTGATTTTTCCCGGGG
TGTTTATTCATCGGAACGCGTCAAAACTTCTTTTATGGGATTTTTCCCGGCCGAGGATCCCCAGATTGCCATGCTGGTCA
TTCTTGACGAGCCACAGAAGGACCGGTGGGGCGGTGTCGCTTCAGCCCCTGTTTTCAAGGCTATCGGCGAACAGATCCTG
ATGTGTTTTAAAACCCATATCCGTCCCAATCCTCTTCCCGGAATGGAGCAGGAAAAGAACATCAACAACTCGGACATCAG
CCTCAGTCTGGTTTCTTCTTCCCGGATAATCAATGCTGATGCGGCAGCGAGTTTGGAAGCAGATGAATCATTAATTCCTG
ATTTTCTCGGACTGAGCATCCGGGATGTTCTCAGAACAGCGAGGAAACGAGGTATTGAAGTCAGGATCGAGGGCAATGGA
TGGGCTGTTAAACAGCATCCGGTACCCGGCACACCGATAGCGCATTCAACCCATTGTTCCGTGATCTTCGATCACGGGAA
TTAA

Upstream 100 bases:

>100_bases
AGGCGCCGAATCGTATCGAATCCATTGCGAAAGAGAAATTGCAGATGGTGTACCCTCAAAGAGAACAGGTGATTCATCTT
GGGGAAATCGGGGACAAACA

Downstream 100 bases:

>100_bases
AAAGGCCTTTATGAAATGAACCTTTCGATCTTGTTGAAGGGAATCAACATTCTGGGAATTTCCGGACCTTCAGGCAGTGA
AGTGAACGTGAGTTCCGTAT

Product: division specific D,D-transpeptidase / cell division protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MSTESKKWLKFRLMTLLVFFVILFVALFSRALHLQILSGETLKILAEKQHTKTLLLPPERGIIFDRNGEKIAASLQVDSV
CADPSKMARPADAAERITSLLNIDRQVVMKKLLHSKNFCWIARRIPPELAQKVEEAKIEGVFLVKEPKRFYPNGDLAGQL
VGLVGLDSVGLEGLEIKYDQYLKGTPEKLIWTRDAKGRILYHRAEKASVSSDESINMILTIDSRIQYLVESQLKAAVQEK
GAKGGLAIVMDPKTGEILALANSPSFDPNVLLSVSSNNKKNKVITDCFDPGSTFKPFLVAAALEEGTVRENDRFYCENGS
YTIANRVIHEANRKRHGALTVHDILKYSSNIGSVKIAEKLGKEKFYEYIRAFGFGAKTGIDLPGEIPGLLRPVDNWTRVD
AATIAFGQGVSVTAIQMITALSTIANQGTMMKPYVVKALVDKKGQIVHNYSPTAVRQVISPDTARRLTAIMTDVVGQEDG
TGKNARIENVSVAGKTGTAQKFDFSRGVYSSERVKTSFMGFFPAEDPQIAMLVILDEPQKDRWGGVASAPVFKAIGEQIL
MCFKTHIRPNPLPGMEQEKNINNSDISLSLVSSSRIINADAAASLEADESLIPDFLGLSIRDVLRTARKRGIEVRIEGNG
WAVKQHPVPGTPIAHSTHCSVIFDHGN

Sequences:

>Translated_667_residues
MSTESKKWLKFRLMTLLVFFVILFVALFSRALHLQILSGETLKILAEKQHTKTLLLPPERGIIFDRNGEKIAASLQVDSV
CADPSKMARPADAAERITSLLNIDRQVVMKKLLHSKNFCWIARRIPPELAQKVEEAKIEGVFLVKEPKRFYPNGDLAGQL
VGLVGLDSVGLEGLEIKYDQYLKGTPEKLIWTRDAKGRILYHRAEKASVSSDESINMILTIDSRIQYLVESQLKAAVQEK
GAKGGLAIVMDPKTGEILALANSPSFDPNVLLSVSSNNKKNKVITDCFDPGSTFKPFLVAAALEEGTVRENDRFYCENGS
YTIANRVIHEANRKRHGALTVHDILKYSSNIGSVKIAEKLGKEKFYEYIRAFGFGAKTGIDLPGEIPGLLRPVDNWTRVD
AATIAFGQGVSVTAIQMITALSTIANQGTMMKPYVVKALVDKKGQIVHNYSPTAVRQVISPDTARRLTAIMTDVVGQEDG
TGKNARIENVSVAGKTGTAQKFDFSRGVYSSERVKTSFMGFFPAEDPQIAMLVILDEPQKDRWGGVASAPVFKAIGEQIL
MCFKTHIRPNPLPGMEQEKNINNSDISLSLVSSSRIINADAAASLEADESLIPDFLGLSIRDVLRTARKRGIEVRIEGNG
WAVKQHPVPGTPIAHSTHCSVIFDHGN
>Mature_666_residues
STESKKWLKFRLMTLLVFFVILFVALFSRALHLQILSGETLKILAEKQHTKTLLLPPERGIIFDRNGEKIAASLQVDSVC
ADPSKMARPADAAERITSLLNIDRQVVMKKLLHSKNFCWIARRIPPELAQKVEEAKIEGVFLVKEPKRFYPNGDLAGQLV
GLVGLDSVGLEGLEIKYDQYLKGTPEKLIWTRDAKGRILYHRAEKASVSSDESINMILTIDSRIQYLVESQLKAAVQEKG
AKGGLAIVMDPKTGEILALANSPSFDPNVLLSVSSNNKKNKVITDCFDPGSTFKPFLVAAALEEGTVRENDRFYCENGSY
TIANRVIHEANRKRHGALTVHDILKYSSNIGSVKIAEKLGKEKFYEYIRAFGFGAKTGIDLPGEIPGLLRPVDNWTRVDA
ATIAFGQGVSVTAIQMITALSTIANQGTMMKPYVVKALVDKKGQIVHNYSPTAVRQVISPDTARRLTAIMTDVVGQEDGT
GKNARIENVSVAGKTGTAQKFDFSRGVYSSERVKTSFMGFFPAEDPQIAMLVILDEPQKDRWGGVASAPVFKAIGEQILM
CFKTHIRPNPLPGMEQEKNINNSDISLSLVSSSRIINADAAASLEADESLIPDFLGLSIRDVLRTARKRGIEVRIEGNGW
AVKQHPVPGTPIAHSTHCSVIFDHGN

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=593, Percent_Identity=31.0286677908938, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1786854, Length=613, Percent_Identity=23.8172920065253, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 73383; Mature: 73251

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTESKKWLKFRLMTLLVFFVILFVALFSRALHLQILSGETLKILAEKQHTKTLLLPPER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEECCCCCEEEECCCC
GIIFDRNGEKIAASLQVDSVCADPSKMARPADAAERITSLLNIDRQVVMKKLLHSKNFCW
CEEECCCCCEEEEEEEECHHCCCHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEE
IARRIPPELAQKVEEAKIEGVFLVKEPKRFYPNGDLAGQLVGLVGLDSVGLEGLEIKYDQ
EEECCCHHHHHHHHHHHCCEEEEEECCHHHCCCCCHHHHHHHHEECCCCCCCCEEEEHHH
YLKGTPEKLIWTRDAKGRILYHRAEKASVSSDESINMILTIDSRIQYLVESQLKAAVQEK
HHCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHC
GAKGGLAIVMDPKTGEILALANSPSFDPNVLLSVSSNNKKNKVITDCFDPGSTFKPFLVA
CCCCCEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCHHHHH
AALEEGTVRENDRFYCENGSYTIANRVIHEANRKRHGALTVHDILKYSSNIGSVKIAEKL
HHHHCCCCCCCCCEEEECCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHH
GKEKFYEYIRAFGFGAKTGIDLPGEIPGLLRPVDNWTRVDAATIAFGQGVSVTAIQMITA
CHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCHHCCCEEEEECCCCCHHHHHHHHH
LSTIANQGTMMKPYVVKALVDKKGQIVHNYSPTAVRQVISPDTARRLTAIMTDVVGQEDG
HHHHHCCCCCCCHHHHHHHHCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
TGKNARIENVSVAGKTGTAQKFDFSRGVYSSERVKTSFMGFFPAEDPQIAMLVILDEPQK
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHEECCCCCCCCEEEEEEECCCCC
DRWGGVASAPVFKAIGEQILMCFKTHIRPNPLPGMEQEKNINNSDISLSLVSSSRIINAD
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCEEEEEECCCEEECCC
AAASLEADESLIPDFLGLSIRDVLRTARKRGIEVRIEGNGWAVKQHPVPGTPIAHSTHCS
CCCCCCCCHHHCCHHHCCCHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCCCCCCEEE
VIFDHGN
EEEECCC
>Mature Secondary Structure 
STESKKWLKFRLMTLLVFFVILFVALFSRALHLQILSGETLKILAEKQHTKTLLLPPER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEECCCCCEEEECCCC
GIIFDRNGEKIAASLQVDSVCADPSKMARPADAAERITSLLNIDRQVVMKKLLHSKNFCW
CEEECCCCCEEEEEEEECHHCCCHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEE
IARRIPPELAQKVEEAKIEGVFLVKEPKRFYPNGDLAGQLVGLVGLDSVGLEGLEIKYDQ
EEECCCHHHHHHHHHHHCCEEEEEECCHHHCCCCCHHHHHHHHEECCCCCCCCEEEEHHH
YLKGTPEKLIWTRDAKGRILYHRAEKASVSSDESINMILTIDSRIQYLVESQLKAAVQEK
HHCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHC
GAKGGLAIVMDPKTGEILALANSPSFDPNVLLSVSSNNKKNKVITDCFDPGSTFKPFLVA
CCCCCEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCHHHHH
AALEEGTVRENDRFYCENGSYTIANRVIHEANRKRHGALTVHDILKYSSNIGSVKIAEKL
HHHHCCCCCCCCCEEEECCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHH
GKEKFYEYIRAFGFGAKTGIDLPGEIPGLLRPVDNWTRVDAATIAFGQGVSVTAIQMITA
CHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCHHCCCEEEEECCCCCHHHHHHHHH
LSTIANQGTMMKPYVVKALVDKKGQIVHNYSPTAVRQVISPDTARRLTAIMTDVVGQEDG
HHHHHCCCCCCCHHHHHHHHCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
TGKNARIENVSVAGKTGTAQKFDFSRGVYSSERVKTSFMGFFPAEDPQIAMLVILDEPQK
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHEECCCCCCCCEEEEEEECCCCC
DRWGGVASAPVFKAIGEQILMCFKTHIRPNPLPGMEQEKNINNSDISLSLVSSSRIINAD
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCEEEEEECCCEEECCC
AAASLEADESLIPDFLGLSIRDVLRTARKRGIEVRIEGNGWAVKQHPVPGTPIAHSTHCS
CCCCCCCCHHHCCHHHCCCHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCCCCCCEEE
VIFDHGN
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]