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The map label for this gene is atpH

Identifier: 85858474

GI number: 85858474

Start: 630085

End: 630630

Strand: Direct

Name: atpH

Synonym: SYN_00547

Alternate gene names: 85858474

Gene position: 630085-630630 (Clockwise)

Preceding gene: 85858473

Following gene: 85858475

Centisome position: 19.82

GC content: 43.96

Gene sequence:

>546_bases
TTGATCAACAGCGGTATTGCAAAGCGGTATGCCAGAGCGTTCTTTGATATTGCCGGCGAAGACAAACTCTACGAAAAGTA
TTATGAAGAGTTGAGTGGATTCGCACGGATCGTTCAGGGAGACAGAAATCTTAAGGAATTTCTTGCGAATCCTGTCTTCA
ATCAGGCTGAAAAGAAAGCTGTAGTGGAAGCAATTATTCAGAAGATCAGAATGTCGGATATGACGACGAACTTTTTGAAA
TTGCTGGTGGATAAGAAAAGAATAGGAATGCTTGCCGAAATTGCGGATTACTATCGCGTATTGATGGATGAAGTATTGAA
GAGAGTCCGGGTGAGTGTGAAAACGGCTTTTCCGTTGCCGGCTGATGTGACCTCGGACATTAAGCAGGGTCTGGAACAGA
TGACCGGCAAGCAGACAGAAATCGTTGTTGAGGAAGATCGTTCTCTGCTGGGTGGTATTGTCATCAGAGTAGGGGATACG
CTTTATGATGGAAGCATAAAGACTCAGTTGAGTAATATAAGGAATCTCTTAGGGGAGGCAGTATAG

Upstream 100 bases:

>100_bases
TGTCCGTCCATGTGGCTGAAGATATTTTAAAGAGGAATATAACCCCGGAAGATCATCAGAGTATGGTTAAAGATTACTTG
GATAAGGTGGTGAGAAAACA

Downstream 100 bases:

>100_bases
ACCATGGATACAATCAAGGCAGAGGAAATAAGTCAAATAATATCCAAGCAAATTCGGGATTATGAGAAGAAGCTTGATGT
CAGTGAAACCGGTACCGTCC

Product: ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MINSGIAKRYARAFFDIAGEDKLYEKYYEELSGFARIVQGDRNLKEFLANPVFNQAEKKAVVEAIIQKIRMSDMTTNFLK
LLVDKKRIGMLAEIADYYRVLMDEVLKRVRVSVKTAFPLPADVTSDIKQGLEQMTGKQTEIVVEEDRSLLGGIVIRVGDT
LYDGSIKTQLSNIRNLLGEAV

Sequences:

>Translated_181_residues
MINSGIAKRYARAFFDIAGEDKLYEKYYEELSGFARIVQGDRNLKEFLANPVFNQAEKKAVVEAIIQKIRMSDMTTNFLK
LLVDKKRIGMLAEIADYYRVLMDEVLKRVRVSVKTAFPLPADVTSDIKQGLEQMTGKQTEIVVEEDRSLLGGIVIRVGDT
LYDGSIKTQLSNIRNLLGEAV
>Mature_181_residues
MINSGIAKRYARAFFDIAGEDKLYEKYYEELSGFARIVQGDRNLKEFLANPVFNQAEKKAVVEAIIQKIRMSDMTTNFLK
LLVDKKRIGMLAEIADYYRVLMDEVLKRVRVSVKTAFPLPADVTSDIKQGLEQMTGKQTEIVVEEDRSLLGGIVIRVGDT
LYDGSIKTQLSNIRNLLGEAV

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=179, Percent_Identity=27.3743016759777, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71984710, Length=179, Percent_Identity=23.463687150838, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71984717, Length=179, Percent_Identity=23.463687150838, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320504, Length=182, Percent_Identity=23.6263736263736, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647054, Length=168, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_SYNAS (Q2LQZ8)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_460676.1
- ProteinModelPortal:   Q2LQZ8
- SMR:   Q2LQZ8
- STRING:   Q2LQZ8
- GeneID:   3884821
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00547
- NMPDR:   fig|56780.10.peg.623
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- PhylomeDB:   Q2LQZ8
- BioCyc:   SACI56780:SYN_00547-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 20456; Mature: 20456

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSGIAKRYARAFFDIAGEDKLYEKYYEELSGFARIVQGDRNLKEFLANPVFNQAEKKA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHH
VVEAIIQKIRMSDMTTNFLKLLVDKKRIGMLAEIADYYRVLMDEVLKRVRVSVKTAFPLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ADVTSDIKQGLEQMTGKQTEIVVEEDRSLLGGIVIRVGDTLYDGSIKTQLSNIRNLLGEA
CCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHCC
V
C
>Mature Secondary Structure
MINSGIAKRYARAFFDIAGEDKLYEKYYEELSGFARIVQGDRNLKEFLANPVFNQAEKKA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHH
VVEAIIQKIRMSDMTTNFLKLLVDKKRIGMLAEIADYYRVLMDEVLKRVRVSVKTAFPLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ADVTSDIKQGLEQMTGKQTEIVVEEDRSLLGGIVIRVGDTLYDGSIKTQLSNIRNLLGEA
CCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA