Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 85858471

GI number: 85858471

Start: 627617

End: 628726

Strand: Direct

Name: mrdB [H]

Synonym: SYN_00550

Alternate gene names: 85858471

Gene position: 627617-628726 (Clockwise)

Preceding gene: 85858470

Following gene: 85858472

Centisome position: 19.74

GC content: 45.95

Gene sequence:

>1110_bases
ATGAGGTTTGACCGTCGACTGATCTTTAATTTTGACTGGACCCTGCTTATCCTTGTACTGACGATCTGTGCGGTAGGGGT
TTTAAACATCTACAGTGCCGGTTACAGCTTTTCCGGCACCAAGGCAAATCCCTTCTATATCAAGCAGTTACAGTGGATAC
TGATTGGTCTTTTCTGCATGAGTATCGTGTTTTGCCTTGATTACCGATTGATCAGTCAATATGCTTACATTCTGCATGGC
GTGGCGGTTTTATTTCTGATCATCGTCTTTTTTCACGGGTATGCAACACATGGGTCGCAACGCTGGATTTCCCTGGGGAA
TTTTTCTTTTCAGCCTTCTGAACTGGTCAAATTAACTATTATACTGGCGCTTGCAAAATATTTCGATGATCATAAGCTTA
CCTCAGGTTATCGCCTGAGGGAGCTGCTGATTCCCTTCCTGTTTCTTCTGGTTCCCTTTATCCTGATTCTGAAGCAGCCC
GATCTGGGAACCGCACTGGTCCTTCTTATTGTTTTCGCCTCCATGATCCTGTTTGTGGGAATCCGGTGGAAATCGCTGGC
CTGCGTAATTTCGCTGGTTGTTTCCATGACGCCTGTCAGCTGGTATTTTCTGAAAGAATATCAAAGAGAAAGAGTTCTAA
CTTTTTTGAATCCCGAACGCGATCCCCTGGGATCCGGATATCATATCATCCAGTCCATGATCGCAGTTGGCTCGGGGGGG
ATTCTTGGCAAAGGATACCTGAAAGGAACTCAGACGCAGCTGCAGTTTCTTCCGGAACAACAGACGGATTTTGTTTTTTC
TGTATTTGCCGAAGAGTGGGGATTCCTGGGAGGGGGGATGGTGATCGTCCTTTTTATGTCTCTGATTCTCTGGAGTCTGA
AAATCGCTCTCCATTCACGGGATTTTCTGGGAACATTGATTGCGTACGGACTGGCGGTCCTGTTTTTTTGGGAAGTCTTA
ATCAATATCGGAATGGTTCTTGGGATGATGCCCGTTGTAGGCATTCCCCTGCCTTTCTTGAGTTACGGCGGCTCAGCCAT
TGTTTCATTGCTGATCTGTGTAGGATTGCTTTTAAATGTCAGTATGAGAAGGTATATTCTGCAGCCCTGA

Upstream 100 bases:

>100_bases
CTGCAAAACAACCGTAAAAAGGGATGAGGGCAGGATTGAAAAAGATGAAATCGCGAAATAATAAAAATATCGGCAAATTG
AATTTTTCAGTGGGCGCGGC

Downstream 100 bases:

>100_bases
GATATGCAAACGGAAAAGAATGAAGCTGACATGAAGAACGTAATTTCCATCCAAAAGTTCTTGACAATCACTTTGAGTTA
TGATTAATGCAAGCTCGCCT

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MRFDRRLIFNFDWTLLILVLTICAVGVLNIYSAGYSFSGTKANPFYIKQLQWILIGLFCMSIVFCLDYRLISQYAYILHG
VAVLFLIIVFFHGYATHGSQRWISLGNFSFQPSELVKLTIILALAKYFDDHKLTSGYRLRELLIPFLFLLVPFILILKQP
DLGTALVLLIVFASMILFVGIRWKSLACVISLVVSMTPVSWYFLKEYQRERVLTFLNPERDPLGSGYHIIQSMIAVGSGG
ILGKGYLKGTQTQLQFLPEQQTDFVFSVFAEEWGFLGGGMVIVLFMSLILWSLKIALHSRDFLGTLIAYGLAVLFFWEVL
INIGMVLGMMPVVGIPLPFLSYGGSAIVSLLICVGLLLNVSMRRYILQP

Sequences:

>Translated_369_residues
MRFDRRLIFNFDWTLLILVLTICAVGVLNIYSAGYSFSGTKANPFYIKQLQWILIGLFCMSIVFCLDYRLISQYAYILHG
VAVLFLIIVFFHGYATHGSQRWISLGNFSFQPSELVKLTIILALAKYFDDHKLTSGYRLRELLIPFLFLLVPFILILKQP
DLGTALVLLIVFASMILFVGIRWKSLACVISLVVSMTPVSWYFLKEYQRERVLTFLNPERDPLGSGYHIIQSMIAVGSGG
ILGKGYLKGTQTQLQFLPEQQTDFVFSVFAEEWGFLGGGMVIVLFMSLILWSLKIALHSRDFLGTLIAYGLAVLFFWEVL
INIGMVLGMMPVVGIPLPFLSYGGSAIVSLLICVGLLLNVSMRRYILQP
>Mature_369_residues
MRFDRRLIFNFDWTLLILVLTICAVGVLNIYSAGYSFSGTKANPFYIKQLQWILIGLFCMSIVFCLDYRLISQYAYILHG
VAVLFLIIVFFHGYATHGSQRWISLGNFSFQPSELVKLTIILALAKYFDDHKLTSGYRLRELLIPFLFLLVPFILILKQP
DLGTALVLLIVFASMILFVGIRWKSLACVISLVVSMTPVSWYFLKEYQRERVLTFLNPERDPLGSGYHIIQSMIAVGSGG
ILGKGYLKGTQTQLQFLPEQQTDFVFSVFAEEWGFLGGGMVIVLFMSLILWSLKIALHSRDFLGTLIAYGLAVLFFWEVL
INIGMVLGMMPVVGIPLPFLSYGGSAIVSLLICVGLLLNVSMRRYILQP

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=322, Percent_Identity=38.8198757763975, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=31.043956043956, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41698; Mature: 41698

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDRRLIFNFDWTLLILVLTICAVGVLNIYSAGYSFSGTKANPFYIKQLQWILIGLFCM
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SIVFCLDYRLISQYAYILHGVAVLFLIIVFFHGYATHGSQRWISLGNFSFQPSELVKLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHH
ILALAKYFDDHKLTSGYRLRELLIPFLFLLVPFILILKQPDLGTALVLLIVFASMILFVG
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IRWKSLACVISLVVSMTPVSWYFLKEYQRERVLTFLNPERDPLGSGYHIIQSMIAVGSGG
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
ILGKGYLKGTQTQLQFLPEQQTDFVFSVFAEEWGFLGGGMVIVLFMSLILWSLKIALHSR
CEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DFLGTLIAYGLAVLFFWEVLINIGMVLGMMPVVGIPLPFLSYGGSAIVSLLICVGLLLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHH
SMRRYILQP
HHHHHHCCC
>Mature Secondary Structure
MRFDRRLIFNFDWTLLILVLTICAVGVLNIYSAGYSFSGTKANPFYIKQLQWILIGLFCM
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SIVFCLDYRLISQYAYILHGVAVLFLIIVFFHGYATHGSQRWISLGNFSFQPSELVKLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHH
ILALAKYFDDHKLTSGYRLRELLIPFLFLLVPFILILKQPDLGTALVLLIVFASMILFVG
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IRWKSLACVISLVVSMTPVSWYFLKEYQRERVLTFLNPERDPLGSGYHIIQSMIAVGSGG
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
ILGKGYLKGTQTQLQFLPEQQTDFVFSVFAEEWGFLGGGMVIVLFMSLILWSLKIALHSR
CEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DFLGTLIAYGLAVLFFWEVLINIGMVLGMMPVVGIPLPFLSYGGSAIVSLLICVGLLLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHH
SMRRYILQP
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]