Click here to switch to the map view.

The map label for this gene is rpoC

Identifier: 85858139

GI number: 85858139

Start: 306953

End: 311098

Strand: Direct

Name: rpoC

Synonym: SYN_00063

Alternate gene names: 85858139

Gene position: 306953-311098 (Clockwise)

Preceding gene: 85858138

Following gene: 85858140

Centisome position: 9.65

GC content: 50.07

Gene sequence:

>4146_bases
GTGGAAGATGTTTTTAGCTATTTTGAAAAACCAAAAGATCCGATTCGCTTTAATGCGATAAAAATTTCGATTGCCTCACC
GGACAAGATCCTTTCCTGGTCTTACGGCGAGGTTAAAAAGCCGGAAACCATTAATTACCGAACTTTCAAGCCTGAACGTG
ACGGGCTTTTCTGCGCAAAAATATTTGGTCCTGTGAAGGATTATGAGTGTCTCTGCGGACGCTACAAGCGAATGAAGCAC
AGGGGCGTGGTCTGTGAGAAGTGTGGCGTTGAAGTCATCAAGTCGAAGGTTCGTCGTGAGAGGATGGGGCATATTACCCT
GGCAACGCCGGTTGCCCATATCTGGTTTCTCAAGAGTCTACCCAGCAGGATCGGAAATGTCCTGGACCTTACTTTAAAGG
AATTGGAGCGGATTCTCTATTTTGAATCCTGGATCGTTCTCGATCCCAGGAACACTCCGCTGCGGAAGAAGGATTTACTT
TCGGATGAGGAGTATAACGATCTGAGAGAGCAGTACGGTCCGGATGGATTCCAGGCTGGAATCGGTGCCGAGGCTGTGAG
AAAACTTCTTGAAGAAGTCGATCTTGAGGGGCTCGATGTAGAACTGCGGGATGAGTTGAAGACCGCCTCGTCGGATACCA
AGAGGAAGAAAGTCATCAAGCGATTGAAGGTTATCGAGGCTCTACGGAAATCGGGAAATCGTCCGGAGTGGATGATTCTG
ACGGTGCTACCCGTTATCCCTCCGGATCTGCGTCCCCTTGTTCCTCTGGATGGGGGGCGGTTTGCCACCTCGGATTTGAA
TGACCTTTACCGCCGTGTGATCAACCGGAATAACAGGCTTAAGCGCCTTCAGGAGTTGAACGCTCCTGAAATTATTATTC
GCAATGAAAAAAGAATGCTTCAGGAAGCCGTAGACGTTCTTTTTGATAACGGCAGAAGAGGGAGGGCCATAACGGGGACC
AACAAGAGGCCCTTAAAATCTCTTTCCGATATGCTCAAGGGGAAACAGGGGCGATTCAGACAGAATCTTCTGGGTAAGCG
AGTGGATTATTCAGGCCGTTCCGTGATCACCGTTGGTCCCGACCTGCGGCTGCATCAGTGTGGATTGCCTAAAAAAATGG
CCCTCGAATTGTTTAAACCATTTGTTTACAACAGGCTACAGGAAAAAGGGTACGTCACAACCGTCAAAAGCGCAAAGAAG
ATGGTCGAGCGGGAGACGGCGGAGGTCTGGGATGCTTTGGATGAAGTTGTCCGGGAGTATCCGGTTATGCTGAACCGTGC
GCCGACGCTGCATCGACTGGGACTGCAGGCTTTTGAGCCGGTATTGATAGAAGGAAAAGCCATTCAGCTCCATCCTCTCG
TCTGCACGGCCTTTAACGCGGATTTCGACGGCGATCAGATGGCCGTTCACGTACCGTTATCGATTGAGGCCCAGACGGAA
GCCCGGGTTCTCATGATGTCGACGAACAATATTCTTTCACCGGCAAATGGCAAGCCCATAATCATCCCCAGCCAGGATGT
TGTGCTGGGAATATATTATCTGACGCGTTCAAAGGAAGATGTCCTGGGACATGGCATGAGCTTTTCCAATCCCGAGGAGG
TTCGCTCCGCCTTCGACGCCGGAGCGGTGGAACTACGCGCCAGGATAAAAGTGCGAATCGATGATGAATTGAAGGAGACG
ACCGTAGGACGGGTCATTTTGTATGAGATTATTCCGGAAGCCATTTCTTTTGATGTCATTAATAAAGTGATGAACAAAAA
AGAACTGGCTAATCTGATCGATTACTGCTACCGGCTCTGTGGGGAAAAGACGACGGTTATTCTTGCAGACCGCCTGAAAG
ATATGGGTTTCAAATATGCGACCCATTCAGGGATGTCTTTTGCGGTAAGAAACCTGAATATCCCAAAAAACAAGAAAGAT
ATTGTTGTTCGGGCGGACCGCGACGTTCTGGAAATTCAAAAGCAGTACATGGACGGTTTGATTACCGACGGTGAACGATA
CAATAAGGTGATCGATCTATGGGCCCAGGCGACGGAAAAAATCGCTTCGGAAATGATGGGGGGTATCGAAACCGAGGAGC
AGATTACGACGGAAGGGAAGAAAGTTGTAGAAAGCTTCAATCCGATCTACATGATGGCAGATTCCGGAGCGAGAGGCAGT
AATGCACAGATTCGACAGTTGGCCGGTATGCGGGGGTTGATGGCGAAACCTTCAGGAGAAATTATTGAAACGCCGATTAC
GGCAAACTTCCGGGAAGGTTTGACCGTTCTGCAGTACTTCATTTCAACACACGGAGCAAGAAAGGGGCTTGCCGATACAG
CGCTGAAAACGGCGAACTCCGGTTACCTGACACGGCGGCTGGTTGACGTCGCTCAGGATTGCATTATCACCCAGCAGGAT
TGCGGAACGGTGGATGGCATATCCGTGTCGGCCCTGATGGAGGGCGGAGAGATTATAGAGACAGCTGGAGAACGTGTTCT
TGGGCGTGTCGTGCTTGAAGATATCATGGATCCTTTTACCGGCGAAGTCCTCGTCGGTGCAAATCAGGAAATCGATGAAT
CCCTTTCGGAAAAAATTGACAGGGCGGGGATTGAAAGCGTGAGAATCCGTTCTGTTCTGACCTGCAAGGCCAAGTATGGC
GTTTGTGCACGGTGTTACGGCCGGGACTTGGGTCATGGTCACCTTGTGAATATCGGAGAAGCCGTGGGGATTATTGCTGC
CCAGTCCATTGGAGAACCGGGAACCCAGTTGACTATGAGAACTTTCCATATCGGAGGTACGGCGAAATTTGAAGAGCACT
CAACTCTGGATTCCCGGCACGATGGCATTGTGAAATACGTTGACCTCAACTACGTAGTCAGCAAGATAGGGGAAACGGTT
GTCATGAGCCGCCATGGGGAAATTCACGTCCTTGATGAGCAGTTGAGAAGTCGAGGCAAGTATACTGTCCCATACGGTGC
CCACCTGAAAGTTAAAGACGGTCAGTCCGTCAAAAGAGGGGATCGCATGGCCGAGTGGGATCCTTTCTCAATACCCATTC
TTGCTGAAGTCGATGGAACCGTGAAGTTTGGTGATATCATCGAAGGAAAGACGATGCAGGAACAGGTTGACGAAGTTACC
GGTCTTTCCCGTAAAGTTATTGTTGAATTCAAGGGGGCGGACCTCAGGCCTCGAGTTTCCTTAAAGGATGCCACAGGAAA
GACAGCCAAGGTTCCCGGCACAAACGCGGCGGCAAGACATCTTCTTTCAGTAGGCGTGAACATCGTTGTCTCTGAAGGAG
ACCAGGTCAAAGCCGGTGACATTATCGCCAAGATCCCCAGAGAAACGACCAAAACGAAAGATATTACCGGTGGTCTTCCG
AGGGTTGCAGAGCTTTTTGAAGCGCGGAAGCCCAAGGATTTCGCCGTTATTTCTGAAATCGACGGCGTGGTGTCCTACGG
CAAGGATGCCAAGGGAAAAAGAAAGGTGATCGTAACTCCGGAAATCGGCGATGAAAAGGAATACCTCATCCCCAAAGGAA
AGCATGTCAGCGTCCAGGAAGGTGACCGTGTGATCGCCGGGGAAGCTTTAATGAGCGGTGTCAATAATCCTCATGATCTT
CTCATGATCAAGGGAGAAAAAGCCCTGGCTCGCTACCTTGTTGATGAGGTTCAGGAAGTTTACCGACTGCAGGGCGTGAA
GATCAATGACAAACATATGGAAGTCATTGTACGCCAGATGCTGCGGCGGGTGAAAGTTATCGATCCCGGAGACACTCCCT
TCATGGCTGATGAGCAGGTCGAAAAGTTCAGGTTCCAGGAGGAGAATGAAAAGGCCATTGCCAGAGGAGAGCAGCCGGCC
ATTGGGGAACCTGTTCTTCTGGGTATCACCAAGGCTTCTCTGAGTACGCAGAGCTTTATTTCTGCTGCCTCATTCCAGGA
GACGACACGGGTTCTTACGGAAGCGAGTCTGGCGGGCAAGGTGGATTACCTCCGAGGTTTGAAGGAAAATGTGATTATGG
GTAGATTGATTCCTGCCGGGACTGGGCTTGTGATGTATCGCAAGCTCGGTATTAAAACGGTGGCGGACGAGGATGCTGAA
TCAGTGGAAATCGAGGGTGATGAAAATAGCAATAAGAAATCTCTTGACATGCACGCGGCGAATTGA

Upstream 100 bases:

>100_bases
ATTGCAAAGTCTTTGCCTTGATGTGGAGTTGATTGAGGAAGAATAAAGGAAGTCTTCCCGATAAGCATCACCAAGTCATA
TATAAACGGGAGTAAAAACC

Downstream 100 bases:

>100_bases
TAGTTAACCAGACTTTTCTAAGTCAAGTTAGAATTACGTGAAGTATTGTTTTCGGGAGGAGTAATGCCTACAATAAATCA
GTTAGTTCGAAATGGAAGGC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1381; Mature: 1381

Protein sequence:

>1381_residues
MEDVFSYFEKPKDPIRFNAIKISIASPDKILSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGRYKRMKH
RGVVCEKCGVEVIKSKVRRERMGHITLATPVAHIWFLKSLPSRIGNVLDLTLKELERILYFESWIVLDPRNTPLRKKDLL
SDEEYNDLREQYGPDGFQAGIGAEAVRKLLEEVDLEGLDVELRDELKTASSDTKRKKVIKRLKVIEALRKSGNRPEWMIL
TVLPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLQELNAPEIIIRNEKRMLQEAVDVLFDNGRRGRAITGT
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVITVGPDLRLHQCGLPKKMALELFKPFVYNRLQEKGYVTTVKSAKK
MVERETAEVWDALDEVVREYPVMLNRAPTLHRLGLQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQTE
ARVLMMSTNNILSPANGKPIIIPSQDVVLGIYYLTRSKEDVLGHGMSFSNPEEVRSAFDAGAVELRARIKVRIDDELKET
TVGRVILYEIIPEAISFDVINKVMNKKELANLIDYCYRLCGEKTTVILADRLKDMGFKYATHSGMSFAVRNLNIPKNKKD
IVVRADRDVLEIQKQYMDGLITDGERYNKVIDLWAQATEKIASEMMGGIETEEQITTEGKKVVESFNPIYMMADSGARGS
NAQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITQQD
CGTVDGISVSALMEGGEIIETAGERVLGRVVLEDIMDPFTGEVLVGANQEIDESLSEKIDRAGIESVRIRSVLTCKAKYG
VCARCYGRDLGHGHLVNIGEAVGIIAAQSIGEPGTQLTMRTFHIGGTAKFEEHSTLDSRHDGIVKYVDLNYVVSKIGETV
VMSRHGEIHVLDEQLRSRGKYTVPYGAHLKVKDGQSVKRGDRMAEWDPFSIPILAEVDGTVKFGDIIEGKTMQEQVDEVT
GLSRKVIVEFKGADLRPRVSLKDATGKTAKVPGTNAAARHLLSVGVNIVVSEGDQVKAGDIIAKIPRETTKTKDITGGLP
RVAELFEARKPKDFAVISEIDGVVSYGKDAKGKRKVIVTPEIGDEKEYLIPKGKHVSVQEGDRVIAGEALMSGVNNPHDL
LMIKGEKALARYLVDEVQEVYRLQGVKINDKHMEVIVRQMLRRVKVIDPGDTPFMADEQVEKFRFQEENEKAIARGEQPA
IGEPVLLGITKASLSTQSFISAASFQETTRVLTEASLAGKVDYLRGLKENVIMGRLIPAGTGLVMYRKLGIKTVADEDAE
SVEIEGDENSNKKSLDMHAAN

Sequences:

>Translated_1381_residues
MEDVFSYFEKPKDPIRFNAIKISIASPDKILSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGRYKRMKH
RGVVCEKCGVEVIKSKVRRERMGHITLATPVAHIWFLKSLPSRIGNVLDLTLKELERILYFESWIVLDPRNTPLRKKDLL
SDEEYNDLREQYGPDGFQAGIGAEAVRKLLEEVDLEGLDVELRDELKTASSDTKRKKVIKRLKVIEALRKSGNRPEWMIL
TVLPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLQELNAPEIIIRNEKRMLQEAVDVLFDNGRRGRAITGT
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVITVGPDLRLHQCGLPKKMALELFKPFVYNRLQEKGYVTTVKSAKK
MVERETAEVWDALDEVVREYPVMLNRAPTLHRLGLQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQTE
ARVLMMSTNNILSPANGKPIIIPSQDVVLGIYYLTRSKEDVLGHGMSFSNPEEVRSAFDAGAVELRARIKVRIDDELKET
TVGRVILYEIIPEAISFDVINKVMNKKELANLIDYCYRLCGEKTTVILADRLKDMGFKYATHSGMSFAVRNLNIPKNKKD
IVVRADRDVLEIQKQYMDGLITDGERYNKVIDLWAQATEKIASEMMGGIETEEQITTEGKKVVESFNPIYMMADSGARGS
NAQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITQQD
CGTVDGISVSALMEGGEIIETAGERVLGRVVLEDIMDPFTGEVLVGANQEIDESLSEKIDRAGIESVRIRSVLTCKAKYG
VCARCYGRDLGHGHLVNIGEAVGIIAAQSIGEPGTQLTMRTFHIGGTAKFEEHSTLDSRHDGIVKYVDLNYVVSKIGETV
VMSRHGEIHVLDEQLRSRGKYTVPYGAHLKVKDGQSVKRGDRMAEWDPFSIPILAEVDGTVKFGDIIEGKTMQEQVDEVT
GLSRKVIVEFKGADLRPRVSLKDATGKTAKVPGTNAAARHLLSVGVNIVVSEGDQVKAGDIIAKIPRETTKTKDITGGLP
RVAELFEARKPKDFAVISEIDGVVSYGKDAKGKRKVIVTPEIGDEKEYLIPKGKHVSVQEGDRVIAGEALMSGVNNPHDL
LMIKGEKALARYLVDEVQEVYRLQGVKINDKHMEVIVRQMLRRVKVIDPGDTPFMADEQVEKFRFQEENEKAIARGEQPA
IGEPVLLGITKASLSTQSFISAASFQETTRVLTEASLAGKVDYLRGLKENVIMGRLIPAGTGLVMYRKLGIKTVADEDAE
SVEIEGDENSNKKSLDMHAAN
>Mature_1381_residues
MEDVFSYFEKPKDPIRFNAIKISIASPDKILSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGRYKRMKH
RGVVCEKCGVEVIKSKVRRERMGHITLATPVAHIWFLKSLPSRIGNVLDLTLKELERILYFESWIVLDPRNTPLRKKDLL
SDEEYNDLREQYGPDGFQAGIGAEAVRKLLEEVDLEGLDVELRDELKTASSDTKRKKVIKRLKVIEALRKSGNRPEWMIL
TVLPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLQELNAPEIIIRNEKRMLQEAVDVLFDNGRRGRAITGT
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVITVGPDLRLHQCGLPKKMALELFKPFVYNRLQEKGYVTTVKSAKK
MVERETAEVWDALDEVVREYPVMLNRAPTLHRLGLQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQTE
ARVLMMSTNNILSPANGKPIIIPSQDVVLGIYYLTRSKEDVLGHGMSFSNPEEVRSAFDAGAVELRARIKVRIDDELKET
TVGRVILYEIIPEAISFDVINKVMNKKELANLIDYCYRLCGEKTTVILADRLKDMGFKYATHSGMSFAVRNLNIPKNKKD
IVVRADRDVLEIQKQYMDGLITDGERYNKVIDLWAQATEKIASEMMGGIETEEQITTEGKKVVESFNPIYMMADSGARGS
NAQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITQQD
CGTVDGISVSALMEGGEIIETAGERVLGRVVLEDIMDPFTGEVLVGANQEIDESLSEKIDRAGIESVRIRSVLTCKAKYG
VCARCYGRDLGHGHLVNIGEAVGIIAAQSIGEPGTQLTMRTFHIGGTAKFEEHSTLDSRHDGIVKYVDLNYVVSKIGETV
VMSRHGEIHVLDEQLRSRGKYTVPYGAHLKVKDGQSVKRGDRMAEWDPFSIPILAEVDGTVKFGDIIEGKTMQEQVDEVT
GLSRKVIVEFKGADLRPRVSLKDATGKTAKVPGTNAAARHLLSVGVNIVVSEGDQVKAGDIIAKIPRETTKTKDITGGLP
RVAELFEARKPKDFAVISEIDGVVSYGKDAKGKRKVIVTPEIGDEKEYLIPKGKHVSVQEGDRVIAGEALMSGVNNPHDL
LMIKGEKALARYLVDEVQEVYRLQGVKINDKHMEVIVRQMLRRVKVIDPGDTPFMADEQVEKFRFQEENEKAIARGEQPA
IGEPVLLGITKASLSTQSFISAASFQETTRVLTEASLAGKVDYLRGLKENVIMGRLIPAGTGLVMYRKLGIKTVADEDAE
SVEIEGDENSNKKSLDMHAAN

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=935, Percent_Identity=25.5614973262032, Blast_Score=202, Evalue=2e-51,
Organism=Homo sapiens, GI39725938, Length=308, Percent_Identity=32.1428571428571, Blast_Score=134, Evalue=5e-31,
Organism=Homo sapiens, GI103471997, Length=257, Percent_Identity=31.9066147859922, Blast_Score=92, Evalue=3e-18,
Organism=Escherichia coli, GI2367335, Length=1391, Percent_Identity=59.3817397555715, Blast_Score=1710, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=703, Percent_Identity=26.7425320056899, Blast_Score=182, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71987878, Length=572, Percent_Identity=27.6223776223776, Blast_Score=155, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320061, Length=892, Percent_Identity=23.9910313901345, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324690, Length=228, Percent_Identity=35.5263157894737, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17530899, Length=508, Percent_Identity=29.5275590551181, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281360912, Length=642, Percent_Identity=26.1682242990654, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17647875, Length=371, Percent_Identity=26.9541778975741, Blast_Score=105, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_SYNAS (Q2LQ86)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_460341.1
- ProteinModelPortal:   Q2LQ86
- STRING:   Q2LQ86
- GeneID:   3884602
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00063
- NMPDR:   fig|56780.10.peg.295
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q2LQ86
- BioCyc:   SACI56780:SYN_00063-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 153999; Mature: 153999

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDVFSYFEKPKDPIRFNAIKISIASPDKILSWSYGEVKKPETINYRTFKPERDGLFCAK
CCHHHHHHHCCCCCEEEEEEEEEECCCCCEEECCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGRYKRMKHRGVVCEKCGVEVIKSKVRRERMGHITLATPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHH
PSRIGNVLDLTLKELERILYFESWIVLDPRNTPLRKKDLLSDEEYNDLREQYGPDGFQAG
HHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHCCCCCHHHHHHHHHCCCCHHCC
IGAEAVRKLLEEVDLEGLDVELRDELKTASSDTKRKKVIKRLKVIEALRKSGNRPEWMIL
CCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TVLPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLQELNAPEIIIRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECHHHHH
QEAVDVLFDNGRRGRAITGTNKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVITVGP
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
DLRLHQCGLPKKMALELFKPFVYNRLQEKGYVTTVKSAKKMVERETAEVWDALDEVVREY
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
PVMLNRAPTLHRLGLQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQTE
CHHHCCCCHHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEEEEEEECCCC
ARVLMMSTNNILSPANGKPIIIPSQDVVLGIYYLTRSKEDVLGHGMSFSNPEEVRSAFDA
EEEEEEECCCEECCCCCCEEEECCCCCEEEEEEECCCCHHHHHCCCCCCCHHHHHHHHCC
GAVELRARIKVRIDDELKETTVGRVILYEIIPEAISFDVINKVMNKKELANLIDYCYRLC
CCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
GEKTTVILADRLKDMGFKYATHSGMSFAVRNLNIPKNKKDIVVRADRDVLEIQKQYMDGL
CCCEEEEEHHHHHHCCCEEEECCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHCCC
ITDGERYNKVIDLWAQATEKIASEMMGGIETEEQITTEGKKVVESFNPIYMMADSGARGS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCC
NAQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANS
CHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
GYLTRRLVDVAQDCIITQQDCGTVDGISVSALMEGGEIIETAGERVLGRVVLEDIMDPFT
CHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
GEVLVGANQEIDESLSEKIDRAGIESVRIRSVLTCKAKYGVCARCYGRDLGHGHLVNIGE
CCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHEEEHHCCCCHHHHHCCCCCCCCEEEHHH
AVGIIAAQSIGEPGTQLTMRTFHIGGTAKFEEHSTLDSRHDGIVKYVDLNYVVSKIGETV
HHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCEE
VMSRHGEIHVLDEQLRSRGKYTVPYGAHLKVKDGQSVKRGDRMAEWDPFSIPILAEVDGT
EEECCCCEEEEHHHHHCCCCEECCCCCEEEECCCCCHHHCCCCCCCCCCCCEEEEECCCC
VKFGDIIEGKTMQEQVDEVTGLSRKVIVEFKGADLRPRVSLKDATGKTAKVPGTNAAARH
EEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCEEECCCCCHHHHH
LLSVGVNIVVSEGDQVKAGDIIAKIPRETTKTKDITGGLPRVAELFEARKPKDFAVISEI
HHHCCCEEEEECCCCEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEHHHHH
DGVVSYGKDAKGKRKVIVTPEIGDEKEYLIPKGKHVSVQEGDRVIAGEALMSGVNNPHDL
HHHHHCCCCCCCCEEEEECCCCCCCCCEECCCCCEEECCCCCEEEECHHHHHCCCCCCEE
LMIKGEKALARYLVDEVQEVYRLQGVKINDKHMEVIVRQMLRRVKVIDPGDTPFMADEQV
EEECCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCEEECCCCCCCCCHHHH
EKFRFQEENEKAIARGEQPAIGEPVLLGITKASLSTQSFISAASFQETTRVLTEASLAGK
HHHHCCCCCCHHHHCCCCCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VDYLRGLKENVIMGRLIPAGTGLVMYRKLGIKTVADEDAESVEIEGDENSNKKSLDMHAA
HHHHHHHHHHHHEEEEECCCCCEEEHHHHCCEEECCCCCCEEEEECCCCCCCCCCCCCCC
N
C
>Mature Secondary Structure
MEDVFSYFEKPKDPIRFNAIKISIASPDKILSWSYGEVKKPETINYRTFKPERDGLFCAK
CCHHHHHHHCCCCCEEEEEEEEEECCCCCEEECCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGRYKRMKHRGVVCEKCGVEVIKSKVRRERMGHITLATPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHH
PSRIGNVLDLTLKELERILYFESWIVLDPRNTPLRKKDLLSDEEYNDLREQYGPDGFQAG
HHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHCCCCCHHHHHHHHHCCCCHHCC
IGAEAVRKLLEEVDLEGLDVELRDELKTASSDTKRKKVIKRLKVIEALRKSGNRPEWMIL
CCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TVLPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLQELNAPEIIIRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECHHHHH
QEAVDVLFDNGRRGRAITGTNKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVITVGP
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
DLRLHQCGLPKKMALELFKPFVYNRLQEKGYVTTVKSAKKMVERETAEVWDALDEVVREY
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
PVMLNRAPTLHRLGLQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQTE
CHHHCCCCHHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEEEEEEECCCC
ARVLMMSTNNILSPANGKPIIIPSQDVVLGIYYLTRSKEDVLGHGMSFSNPEEVRSAFDA
EEEEEEECCCEECCCCCCEEEECCCCCEEEEEEECCCCHHHHHCCCCCCCHHHHHHHHCC
GAVELRARIKVRIDDELKETTVGRVILYEIIPEAISFDVINKVMNKKELANLIDYCYRLC
CCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
GEKTTVILADRLKDMGFKYATHSGMSFAVRNLNIPKNKKDIVVRADRDVLEIQKQYMDGL
CCCEEEEEHHHHHHCCCEEEECCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHCCC
ITDGERYNKVIDLWAQATEKIASEMMGGIETEEQITTEGKKVVESFNPIYMMADSGARGS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCC
NAQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANS
CHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
GYLTRRLVDVAQDCIITQQDCGTVDGISVSALMEGGEIIETAGERVLGRVVLEDIMDPFT
CHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
GEVLVGANQEIDESLSEKIDRAGIESVRIRSVLTCKAKYGVCARCYGRDLGHGHLVNIGE
CCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHEEEHHCCCCHHHHHCCCCCCCCEEEHHH
AVGIIAAQSIGEPGTQLTMRTFHIGGTAKFEEHSTLDSRHDGIVKYVDLNYVVSKIGETV
HHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCEE
VMSRHGEIHVLDEQLRSRGKYTVPYGAHLKVKDGQSVKRGDRMAEWDPFSIPILAEVDGT
EEECCCCEEEEHHHHHCCCCEECCCCCEEEECCCCCHHHCCCCCCCCCCCCEEEEECCCC
VKFGDIIEGKTMQEQVDEVTGLSRKVIVEFKGADLRPRVSLKDATGKTAKVPGTNAAARH
EEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCEEECCCCCHHHHH
LLSVGVNIVVSEGDQVKAGDIIAKIPRETTKTKDITGGLPRVAELFEARKPKDFAVISEI
HHHCCCEEEEECCCCEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEHHHHH
DGVVSYGKDAKGKRKVIVTPEIGDEKEYLIPKGKHVSVQEGDRVIAGEALMSGVNNPHDL
HHHHHCCCCCCCCEEEEECCCCCCCCCEECCCCCEEECCCCCEEEECHHHHHCCCCCCEE
LMIKGEKALARYLVDEVQEVYRLQGVKINDKHMEVIVRQMLRRVKVIDPGDTPFMADEQV
EEECCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCEEECCCCCCCCCHHHH
EKFRFQEENEKAIARGEQPAIGEPVLLGITKASLSTQSFISAASFQETTRVLTEASLAGK
HHHHCCCCCCHHHHCCCCCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VDYLRGLKENVIMGRLIPAGTGLVMYRKLGIKTVADEDAESVEIEGDENSNKKSLDMHAA
HHHHHHHHHHHHEEEEECCCCCEEEHHHHCCEEECCCCCCEEEEECCCCCCCCCCCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA