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The map label for this gene is rpoB

Identifier: 85858138

GI number: 85858138

Start: 302807

End: 306898

Strand: Direct

Name: rpoB

Synonym: SYN_00064

Alternate gene names: 85858138

Gene position: 302807-306898 (Clockwise)

Preceding gene: 85858137

Following gene: 85858139

Centisome position: 9.52

GC content: 47.85

Gene sequence:

>4092_bases
ATGGGCGAGTTTAGAAAAAATTTCGGCCGAATTGAAGAAATTCTGGAAGTACCCAATTTGATCGATATTCAAACCAGATC
GTATGAAACATTTCTTCAGGAGGATGTAGCTCCAGAAAATCGTAAGAATTTCGGCTTGCAGGGTGCGTTTAAAAGCGTAT
TCCCCATTTCGGATTTCAGCGGAAAGTGTTCCTTGGAATTCGTGAGTTACAAGATAGGGGCTGTTCGTTATGACGTGAAC
GAGTGCATTCAGAAGGGGATGACCTATGCGGCTCCCTTGAAGATTGTGGTTCGACTCGTTGTTTTTGACACGGATCGCTT
GTCCGATCAGAAAAACATCCGGGACATCAAAGAGCAGGAGATTTATTTTGGTGAAATTCCTCTGATGACTGAAAAGGGAA
CTTTCATTGTCAATGGAACGGAACGTGTTATTGTCAGCCAACTACACCGATCGCCAGGCATATTTTTTGACCATGATAAG
GGAAAAACACTTACAAGTGGAAAGTTAATCTATTCAGCCAGAATCATTCCCATCCGGGGGTCCTGGCTTGATCTGGAATT
TGATTCCAAGGATCTTCTCTATGTCCGTATAGACCGTCGCAGGAAGATGCCCGTTACTATTCTCCTCAAGGCAATGGGCT
ACTCAACGGAAGATTTATTGAATTATTTCTATGATGTGGAACATATCTTCTGTGAAGGCGAAAATTTTTACGCTGCTGTC
GATGAGTCTCTTGTAGGGCATAAACTTTATGACGACATAAGAGACATCAACACGGGAGAAATTCTTTTTAAGAAAGGGCG
CCGCATCAATAAGGTGATTCTTAAAAGAATCAGGGAACAGCGTGTCGAGCGAATCAAGATGGATGTCGAGGAGCTTCCAG
GAAGAATACTGGCAACCGATATTCTGGATCCGGAAACAGGGGAGGTTCTCTTCCACTGCAATGAGGCGTTGAGTGCCGCA
GGAATCGATGTGGTGCGGGAAAAAGGAATAAGAGAACTGAGCGTCATCAATCTCGGTGAGGACCTGTCCAATGTTTCAAT
AAGAGACACTCTATTGATTGATCGGATGGAAACTCCGGGAGATGCGATCATCGAAATCTACCGTCGTCTTAGACCAAGCA
ATCCTCCTACACCCGATACGGCTCAGAAGTTTTTTAACAGCCTCTTTTTTGAGAATGAAAGTTACGATCTTTCGACTGTC
GGTCGGGCGAAGATGAACTATAAGCTCCGCCTCGATGTTTCCACGGATGTCACCGTCTTGAGAAAAGAAGACATCATGGC
CGCGGTCAAATATCTCATCGACCTTAAAAACGGCGTCCCGGAGTGCAGCGTGGATGACATCGATCATCTCGGGAACCGGA
GAGTGCGTTCCGTCGGGGAATTGATTGAAAACCAGTATCGGATCGGTTTGGTTCGAATGGAACGCGCCATAAAGGAAAAA
ATGAGTCTTCAGGATATCGAGACGATGATGCCTCATGACCTGGTGAATGTAAAGCCCGTATCCGCCGTGGTCAGTGAATT
CTTCGGCAGCAGTCAGCTTTCGCAGTTTATGGATCAGACGAATCCATTATCCGAGATTACCCATAAGAGACGGTTGTCCG
CCCTGGGGCCTGGCGGATTGACAAGAGAGAGAGCCGGTTTTGAAGTTCGCGATGTTCATCCAACCCATTATGGGCGGATC
TGTCCAGTGGAAACGCCGGAAGGGCCGAACATCGGGTTGATTGTTTCGCTCAGTACCTATGCGCGGGTTAATGAATTCGG
TTTCATCGAGACCCCTTACCGGATAGTAAAAGAAGGGCGGGTTCTGCCGGAAGTTAAATTCCTGACCGCAATCGAGGAAG
AAAACCAGGTTATAGCACCTGCTGACCAACCTGTGAACCACGATGGGAGCTTCAAGGGTGATTTAATCTCTGCAAGGAAG
GGGGGGGATTTTGTCAATGTTGTTCCATCGGAGGTCAACATGGTGGATGTATCGCCTAACCAGTTGGTCAGTGTTGCCGC
AACGCTGATCCCCTTTCTGGAGCATGACGATGCAAACCGTGCCCTGATGGGGTCGAACATGCAGCGGCAAGCCGTGCCTC
TGATGAGGCCGGAGATTCCTCTTGTGGGTACCGGTATGGAGCGGATTGTAGCCCGGGATTCAGGTGCTGTTGTGGTGGCA
AAGAGATCGGGAATTGTTGAGAGTGTCGATGCATCGAGAATTGTCATCAAGTGTGAAAGTGCCGAAAAAACAGATCGAGA
TACCGGTGTTGATATTTATACGCTGATCAAATACCAGCGATCGAATCAGGATACCTGCTTCAACCAGAAGGCCATCGTCA
ACAAGGGCCAGCGTGTCAGGAAAGGGGACATCATCGCCGATGGTCCCGCCACTGATAACGGCGAGCTGGCCCTCGGACAC
AACGTCATGGTGGCCTTCATGTCCTGGGGCGGATACAACTACGAAGATTCCATTCTCGTCAGTGAAAGGATAGTCAAGGA
AGATATCTACACTTCCATTCATATCGAAGAATTTGAGACCATGGCCCGGGACACCAAACTGGGTAAAGAAGATATAACTC
GCGATATCCCTAATGTCGGAGAAGAAGCGCTCCGCAATCTGGATGATAGCGGAATCGTTCGAATGGGGGTTTCCGTCAAA
TCCGGTGATATTCTGGTGGGTAAAATTACACCCAAAGGGGAAACGCAGCTTTCATCTGAAGAAAAGCTTCTCCGGGCGAT
TTTTGGCGAAAAGGCCAGCGACGTAAGAGATACCTCGTTACGTGTCCCGCCGGGCGTAGAGGGGACTGTCATCGATGCCA
AGGTATTTACCAGAAAAGGTGCAGAGAAAGATCATCGCTCACAGTATATCGAAGATGAAGCAATCGCCATGCTTCAGAAA
GACAGAGAAGATGAAATCCGGATTATTACTGAAGCAGTGAAGAAGGAAGTCGGTACATTGCTGCAGGGCAAGCAGTCCGG
TGCGAAGATCGTTGATCCGAAAAGAAAGAAAATTTACCTCAAAAAGGGTGATATTATAACACCCGAGATATTAAGTGAAA
TTCCACTCCATTTATGGAAGGAAATCACTGTGGCAGATGACGAAGAAACAGAGCGGGCTGTAGGTCAGATGATGGCCAAT
CTTTACGATAAGATCGAGGTGGTGGAAGCCTATTTCAATGAGAAGACGGAAAAGCTGAAGGCCAGTGATGAGCTGCCGCC
CGGTGTCATCAAGATGGTCAAAGTCTATATTGCCATCAAAAGGAAACTGCAGGCCGGAGACAAGATGGCGGGAAGACATG
GAAACAAGGGCGTCCTCTCAAGAATCTTGCCTGAAGAGGACATGCCCTATTTCAAGGACGGCAGGCCCGTGGACATCGTA
CTGAATCCCCTTGGAGTTCCCTCGCGCATGAATGTGGGACAGATCCTTGAAACTCATCTCGGTTGGGCTGCGAAAGGTCT
TGGGGAAAAACTCAATGACATGCTGGATTCCTATCAGAAAGGAAATCAGTTGAGGGATGAGTTGAAAGGCATCTACCAGT
CAAGAGAATTCGAAAAATTTGTAGACGGGGCAACCGAAGAAGAAACTTATCAGTTTGTGCGAAAGCTCAGAAGGGGCATC
GCCGTTTCATCGCCCGTGTTTGACGGAGCCACTGAATCTGACATCAGAAATATGCTGAAGCTGGCAAATTTACCTTCAAC
TGGACAGGCTATACTCTATGATGGTCGTACGGGTGAGCCGTTCGATCAGGAAATCACCGTGGGCATGATTTACATGCTGA
AACTTCATCATCTTGTGGATAACAAGATTCATGCACGATCTATAGGACCATACTCACTGGTAACCCAGCAGCCTCTTGGA
GGAAAGGCTCAGTTTGGAGGGCAGCGACTTGGAGAGATGGAAGTCTGGGCGATGGAGGCTTACGGCGCAGCGTATTCACT
GCAGGAATTCTTAACCGTCAAATCAGATGATGTAGCCGGCCGAACGAGGATTTATGAAGCGATCGTCAAAGGCGAGAATA
CATCGGAGCCAGGTCTGCCGGAGTCGTTCAATGTGCTGGTAAAAGAATTGCAAAGTCTTTGCCTTGATGTGGAGTTGATT
GAGGAAGAATAA

Upstream 100 bases:

>100_bases
CAAGAAGAAAATAGAAGAAGTCGGCGGAACCGTAGAAGTAAAATAATTCAAAATAAATAACTGAGCATCTTCGGATGCTC
AGTATAAAGTTAGGAATGCC

Downstream 100 bases:

>100_bases
AGGAAGTCTTCCCGATAAGCATCACCAAGTCATATATAAACGGGAGTAAAAACCGTGGAAGATGTTTTTAGCTATTTTGA
AAAACCAAAAGATCCGATTC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1363; Mature: 1362

Protein sequence:

>1363_residues
MGEFRKNFGRIEEILEVPNLIDIQTRSYETFLQEDVAPENRKNFGLQGAFKSVFPISDFSGKCSLEFVSYKIGAVRYDVN
ECIQKGMTYAAPLKIVVRLVVFDTDRLSDQKNIRDIKEQEIYFGEIPLMTEKGTFIVNGTERVIVSQLHRSPGIFFDHDK
GKTLTSGKLIYSARIIPIRGSWLDLEFDSKDLLYVRIDRRRKMPVTILLKAMGYSTEDLLNYFYDVEHIFCEGENFYAAV
DESLVGHKLYDDIRDINTGEILFKKGRRINKVILKRIREQRVERIKMDVEELPGRILATDILDPETGEVLFHCNEALSAA
GIDVVREKGIRELSVINLGEDLSNVSIRDTLLIDRMETPGDAIIEIYRRLRPSNPPTPDTAQKFFNSLFFENESYDLSTV
GRAKMNYKLRLDVSTDVTVLRKEDIMAAVKYLIDLKNGVPECSVDDIDHLGNRRVRSVGELIENQYRIGLVRMERAIKEK
MSLQDIETMMPHDLVNVKPVSAVVSEFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRI
CPVETPEGPNIGLIVSLSTYARVNEFGFIETPYRIVKEGRVLPEVKFLTAIEEENQVIAPADQPVNHDGSFKGDLISARK
GGDFVNVVPSEVNMVDVSPNQLVSVAATLIPFLEHDDANRALMGSNMQRQAVPLMRPEIPLVGTGMERIVARDSGAVVVA
KRSGIVESVDASRIVIKCESAEKTDRDTGVDIYTLIKYQRSNQDTCFNQKAIVNKGQRVRKGDIIADGPATDNGELALGH
NVMVAFMSWGGYNYEDSILVSERIVKEDIYTSIHIEEFETMARDTKLGKEDITRDIPNVGEEALRNLDDSGIVRMGVSVK
SGDILVGKITPKGETQLSSEEKLLRAIFGEKASDVRDTSLRVPPGVEGTVIDAKVFTRKGAEKDHRSQYIEDEAIAMLQK
DREDEIRIITEAVKKEVGTLLQGKQSGAKIVDPKRKKIYLKKGDIITPEILSEIPLHLWKEITVADDEETERAVGQMMAN
LYDKIEVVEAYFNEKTEKLKASDELPPGVIKMVKVYIAIKRKLQAGDKMAGRHGNKGVLSRILPEEDMPYFKDGRPVDIV
LNPLGVPSRMNVGQILETHLGWAAKGLGEKLNDMLDSYQKGNQLRDELKGIYQSREFEKFVDGATEEETYQFVRKLRRGI
AVSSPVFDGATESDIRNMLKLANLPSTGQAILYDGRTGEPFDQEITVGMIYMLKLHHLVDNKIHARSIGPYSLVTQQPLG
GKAQFGGQRLGEMEVWAMEAYGAAYSLQEFLTVKSDDVAGRTRIYEAIVKGENTSEPGLPESFNVLVKELQSLCLDVELI
EEE

Sequences:

>Translated_1363_residues
MGEFRKNFGRIEEILEVPNLIDIQTRSYETFLQEDVAPENRKNFGLQGAFKSVFPISDFSGKCSLEFVSYKIGAVRYDVN
ECIQKGMTYAAPLKIVVRLVVFDTDRLSDQKNIRDIKEQEIYFGEIPLMTEKGTFIVNGTERVIVSQLHRSPGIFFDHDK
GKTLTSGKLIYSARIIPIRGSWLDLEFDSKDLLYVRIDRRRKMPVTILLKAMGYSTEDLLNYFYDVEHIFCEGENFYAAV
DESLVGHKLYDDIRDINTGEILFKKGRRINKVILKRIREQRVERIKMDVEELPGRILATDILDPETGEVLFHCNEALSAA
GIDVVREKGIRELSVINLGEDLSNVSIRDTLLIDRMETPGDAIIEIYRRLRPSNPPTPDTAQKFFNSLFFENESYDLSTV
GRAKMNYKLRLDVSTDVTVLRKEDIMAAVKYLIDLKNGVPECSVDDIDHLGNRRVRSVGELIENQYRIGLVRMERAIKEK
MSLQDIETMMPHDLVNVKPVSAVVSEFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRI
CPVETPEGPNIGLIVSLSTYARVNEFGFIETPYRIVKEGRVLPEVKFLTAIEEENQVIAPADQPVNHDGSFKGDLISARK
GGDFVNVVPSEVNMVDVSPNQLVSVAATLIPFLEHDDANRALMGSNMQRQAVPLMRPEIPLVGTGMERIVARDSGAVVVA
KRSGIVESVDASRIVIKCESAEKTDRDTGVDIYTLIKYQRSNQDTCFNQKAIVNKGQRVRKGDIIADGPATDNGELALGH
NVMVAFMSWGGYNYEDSILVSERIVKEDIYTSIHIEEFETMARDTKLGKEDITRDIPNVGEEALRNLDDSGIVRMGVSVK
SGDILVGKITPKGETQLSSEEKLLRAIFGEKASDVRDTSLRVPPGVEGTVIDAKVFTRKGAEKDHRSQYIEDEAIAMLQK
DREDEIRIITEAVKKEVGTLLQGKQSGAKIVDPKRKKIYLKKGDIITPEILSEIPLHLWKEITVADDEETERAVGQMMAN
LYDKIEVVEAYFNEKTEKLKASDELPPGVIKMVKVYIAIKRKLQAGDKMAGRHGNKGVLSRILPEEDMPYFKDGRPVDIV
LNPLGVPSRMNVGQILETHLGWAAKGLGEKLNDMLDSYQKGNQLRDELKGIYQSREFEKFVDGATEEETYQFVRKLRRGI
AVSSPVFDGATESDIRNMLKLANLPSTGQAILYDGRTGEPFDQEITVGMIYMLKLHHLVDNKIHARSIGPYSLVTQQPLG
GKAQFGGQRLGEMEVWAMEAYGAAYSLQEFLTVKSDDVAGRTRIYEAIVKGENTSEPGLPESFNVLVKELQSLCLDVELI
EEE
>Mature_1362_residues
GEFRKNFGRIEEILEVPNLIDIQTRSYETFLQEDVAPENRKNFGLQGAFKSVFPISDFSGKCSLEFVSYKIGAVRYDVNE
CIQKGMTYAAPLKIVVRLVVFDTDRLSDQKNIRDIKEQEIYFGEIPLMTEKGTFIVNGTERVIVSQLHRSPGIFFDHDKG
KTLTSGKLIYSARIIPIRGSWLDLEFDSKDLLYVRIDRRRKMPVTILLKAMGYSTEDLLNYFYDVEHIFCEGENFYAAVD
ESLVGHKLYDDIRDINTGEILFKKGRRINKVILKRIREQRVERIKMDVEELPGRILATDILDPETGEVLFHCNEALSAAG
IDVVREKGIRELSVINLGEDLSNVSIRDTLLIDRMETPGDAIIEIYRRLRPSNPPTPDTAQKFFNSLFFENESYDLSTVG
RAKMNYKLRLDVSTDVTVLRKEDIMAAVKYLIDLKNGVPECSVDDIDHLGNRRVRSVGELIENQYRIGLVRMERAIKEKM
SLQDIETMMPHDLVNVKPVSAVVSEFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRIC
PVETPEGPNIGLIVSLSTYARVNEFGFIETPYRIVKEGRVLPEVKFLTAIEEENQVIAPADQPVNHDGSFKGDLISARKG
GDFVNVVPSEVNMVDVSPNQLVSVAATLIPFLEHDDANRALMGSNMQRQAVPLMRPEIPLVGTGMERIVARDSGAVVVAK
RSGIVESVDASRIVIKCESAEKTDRDTGVDIYTLIKYQRSNQDTCFNQKAIVNKGQRVRKGDIIADGPATDNGELALGHN
VMVAFMSWGGYNYEDSILVSERIVKEDIYTSIHIEEFETMARDTKLGKEDITRDIPNVGEEALRNLDDSGIVRMGVSVKS
GDILVGKITPKGETQLSSEEKLLRAIFGEKASDVRDTSLRVPPGVEGTVIDAKVFTRKGAEKDHRSQYIEDEAIAMLQKD
REDEIRIITEAVKKEVGTLLQGKQSGAKIVDPKRKKIYLKKGDIITPEILSEIPLHLWKEITVADDEETERAVGQMMANL
YDKIEVVEAYFNEKTEKLKASDELPPGVIKMVKVYIAIKRKLQAGDKMAGRHGNKGVLSRILPEEDMPYFKDGRPVDIVL
NPLGVPSRMNVGQILETHLGWAAKGLGEKLNDMLDSYQKGNQLRDELKGIYQSREFEKFVDGATEEETYQFVRKLRRGIA
VSSPVFDGATESDIRNMLKLANLPSTGQAILYDGRTGEPFDQEITVGMIYMLKLHHLVDNKIHARSIGPYSLVTQQPLGG
KAQFGGQRLGEMEVWAMEAYGAAYSLQEFLTVKSDDVAGRTRIYEAIVKGENTSEPGLPESFNVLVKELQSLCLDVELIE
EE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=292, Percent_Identity=30.8219178082192, Blast_Score=126, Evalue=2e-28,
Organism=Homo sapiens, GI238908503, Length=292, Percent_Identity=30.8219178082192, Blast_Score=126, Evalue=2e-28,
Organism=Homo sapiens, GI4505941, Length=301, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI212286172, Length=84, Percent_Identity=42.8571428571429, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI33469941, Length=84, Percent_Identity=42.8571428571429, Blast_Score=79, Evalue=4e-14,
Organism=Escherichia coli, GI1790419, Length=1365, Percent_Identity=55.1648351648352, Blast_Score=1486, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=292, Percent_Identity=31.1643835616438, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17552304, Length=306, Percent_Identity=28.4313725490196, Blast_Score=115, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324781, Length=292, Percent_Identity=31.1643835616438, Blast_Score=125, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6324725, Length=247, Percent_Identity=31.5789473684211, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=247, Percent_Identity=30.7692307692308, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17647877, Length=301, Percent_Identity=31.5614617940199, Blast_Score=122, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136444, Length=246, Percent_Identity=28.8617886178862, Blast_Score=110, Evalue=5e-24,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_SYNAS (Q2LQ87)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_460340.1
- ProteinModelPortal:   Q2LQ87
- STRING:   Q2LQ87
- GeneID:   3884601
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00064
- NMPDR:   fig|56780.10.peg.294
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   Q2LQ87
- BioCyc:   SACI56780:SYN_00064-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 153163; Mature: 153032

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFRKNFGRIEEILEVPNLIDIQTRSYETFLQEDVAPENRKNFGLQGAFKSVFPISDFS
CCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCC
GKCSLEFVSYKIGAVRYDVNECIQKGMTYAAPLKIVVRLVVFDTDRLSDQKNIRDIKEQE
CCEEEEEEEEEHHHEEECHHHHHHCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHC
IYFGEIPLMTEKGTFIVNGTERVIVSQLHRSPGIFFDHDKGKTLTSGKLIYSARIIPIRG
EEECCCCEEECCCCEEECCHHHHHHHHHHCCCCCEEECCCCCEEECCEEEEEEEEEEEEC
SWLDLEFDSKDLLYVRIDRRRKMPVTILLKAMGYSTEDLLNYFYDVEHIFCEGENFYAAV
CEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCEEEEH
DESLVGHKLYDDIRDINTGEILFKKGRRINKVILKRIREQRVERIKMDVEELPGRILATD
HHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEE
ILDPETGEVLFHCNEALSAAGIDVVREKGIRELSVINLGEDLSNVSIRDTLLIDRMETPG
CCCCCCCCEEEEECHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCEEEHEEEEECCCCCH
DAIIEIYRRLRPSNPPTPDTAQKFFNSLFFENESYDLSTVGRAKMNYKLRLDVSTDVTVL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCEEEEEEEEEECCCCEEEE
RKEDIMAAVKYLIDLKNGVPECSVDDIDHLGNRRVRSVGELIENQYRIGLVRMERAIKEK
EHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSLQDIETMMPHDLVNVKPVSAVVSEFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
TRERAGFEVRDVHPTHYGRICPVETPEGPNIGLIVSLSTYARVNEFGFIETPYRIVKEGR
CHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCCHHHHHCCC
VLPEVKFLTAIEEENQVIAPADQPVNHDGSFKGDLISARKGGDFVNVVPSEVNMVDVSPN
CCCCHHHHHHHCCCCCEECCCCCCCCCCCCCCCCEEECCCCCCEEEECCCCCEEEECCHH
QLVSVAATLIPFLEHDDANRALMGSNMQRQAVPLMRPEIPLVGTGMERIVARDSGAVVVA
HHHHHHHHHHHHHHCCCCCCHHHCCCCHHHCCCCCCCCCCEECCCHHHHHCCCCCCEEEE
KRSGIVESVDASRIVIKCESAEKTDRDTGVDIYTLIKYQRSNQDTCFNQKAIVNKGQRVR
ECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHCCCCCEE
KGDIIADGPATDNGELALGHNVMVAFMSWGGYNYEDSILVSERIVKEDIYTSIHIEEFET
CCCEEECCCCCCCCCEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHEEEHHHHHH
MARDTKLGKEDITRDIPNVGEEALRNLDDSGIVRMGVSVKSGDILVGKITPKGETQLSSE
HHHHHCCCHHHHHHHCCCHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCHH
EKLLRAIFGEKASDVRDTSLRVPPGVEGTVIDAKVFTRKGAEKDHRSQYIEDEAIAMLQK
HHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DREDEIRIITEAVKKEVGTLLQGKQSGAKIVDPKRKKIYLKKGDIITPEILSEIPLHLWK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEECHHHHHHHHHHHHH
EITVADDEETERAVGQMMANLYDKIEVVEAYFNEKTEKLKASDELPPGVIKMVKVYIAIK
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RKLQAGDKMAGRHGNKGVLSRILPEEDMPYFKDGRPVDIVLNPLGVPSRMNVGQILETHL
HHHHCCCHHCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
GWAAKGLGEKLNDMLDSYQKGNQLRDELKGIYQSREFEKFVDGATEEETYQFVRKLRRGI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
AVSSPVFDGATESDIRNMLKLANLPSTGQAILYDGRTGEPFDQEITVGMIYMLKLHHLVD
EECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHC
NKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYSLQEFLTVKSDDVAG
CCEEECCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHCCHHHHHHHHHCCCCCCCH
RTRIYEAIVKGENTSEPGLPESFNVLVKELQSLCLDVELIEEE
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
GEFRKNFGRIEEILEVPNLIDIQTRSYETFLQEDVAPENRKNFGLQGAFKSVFPISDFS
CHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCC
GKCSLEFVSYKIGAVRYDVNECIQKGMTYAAPLKIVVRLVVFDTDRLSDQKNIRDIKEQE
CCEEEEEEEEEHHHEEECHHHHHHCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHC
IYFGEIPLMTEKGTFIVNGTERVIVSQLHRSPGIFFDHDKGKTLTSGKLIYSARIIPIRG
EEECCCCEEECCCCEEECCHHHHHHHHHHCCCCCEEECCCCCEEECCEEEEEEEEEEEEC
SWLDLEFDSKDLLYVRIDRRRKMPVTILLKAMGYSTEDLLNYFYDVEHIFCEGENFYAAV
CEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCEEEEH
DESLVGHKLYDDIRDINTGEILFKKGRRINKVILKRIREQRVERIKMDVEELPGRILATD
HHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEE
ILDPETGEVLFHCNEALSAAGIDVVREKGIRELSVINLGEDLSNVSIRDTLLIDRMETPG
CCCCCCCCEEEEECHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCEEEHEEEEECCCCCH
DAIIEIYRRLRPSNPPTPDTAQKFFNSLFFENESYDLSTVGRAKMNYKLRLDVSTDVTVL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCEEEEEEEEEECCCCEEEE
RKEDIMAAVKYLIDLKNGVPECSVDDIDHLGNRRVRSVGELIENQYRIGLVRMERAIKEK
EHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSLQDIETMMPHDLVNVKPVSAVVSEFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
TRERAGFEVRDVHPTHYGRICPVETPEGPNIGLIVSLSTYARVNEFGFIETPYRIVKEGR
CHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCCHHHHHCCC
VLPEVKFLTAIEEENQVIAPADQPVNHDGSFKGDLISARKGGDFVNVVPSEVNMVDVSPN
CCCCHHHHHHHCCCCCEECCCCCCCCCCCCCCCCEEECCCCCCEEEECCCCCEEEECCHH
QLVSVAATLIPFLEHDDANRALMGSNMQRQAVPLMRPEIPLVGTGMERIVARDSGAVVVA
HHHHHHHHHHHHHHCCCCCCHHHCCCCHHHCCCCCCCCCCEECCCHHHHHCCCCCCEEEE
KRSGIVESVDASRIVIKCESAEKTDRDTGVDIYTLIKYQRSNQDTCFNQKAIVNKGQRVR
ECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHCCCCCEE
KGDIIADGPATDNGELALGHNVMVAFMSWGGYNYEDSILVSERIVKEDIYTSIHIEEFET
CCCEEECCCCCCCCCEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHEEEHHHHHH
MARDTKLGKEDITRDIPNVGEEALRNLDDSGIVRMGVSVKSGDILVGKITPKGETQLSSE
HHHHHCCCHHHHHHHCCCHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCHH
EKLLRAIFGEKASDVRDTSLRVPPGVEGTVIDAKVFTRKGAEKDHRSQYIEDEAIAMLQK
HHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DREDEIRIITEAVKKEVGTLLQGKQSGAKIVDPKRKKIYLKKGDIITPEILSEIPLHLWK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEECHHHHHHHHHHHHH
EITVADDEETERAVGQMMANLYDKIEVVEAYFNEKTEKLKASDELPPGVIKMVKVYIAIK
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RKLQAGDKMAGRHGNKGVLSRILPEEDMPYFKDGRPVDIVLNPLGVPSRMNVGQILETHL
HHHHCCCHHCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
GWAAKGLGEKLNDMLDSYQKGNQLRDELKGIYQSREFEKFVDGATEEETYQFVRKLRRGI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
AVSSPVFDGATESDIRNMLKLANLPSTGQAILYDGRTGEPFDQEITVGMIYMLKLHHLVD
EECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHC
NKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYSLQEFLTVKSDDVAG
CCEEECCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHCCHHHHHHHHHCCCCCCCH
RTRIYEAIVKGENTSEPGLPESFNVLVKELQSLCLDVELIEEE
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA