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The map label for this gene is fadE25 [H]

Identifier: 85858067

GI number: 85858067

Start: 230609

End: 231853

Strand: Direct

Name: fadE25 [H]

Synonym: SYN_02587

Alternate gene names: 85858067

Gene position: 230609-231853 (Clockwise)

Preceding gene: 85858066

Following gene: 85858079

Centisome position: 7.25

GC content: 54.14

Gene sequence:

>1245_bases
TTGAAGGGGCCAATCAAATTCAACGCATTGTCGTTGCAAGGGAGATCCGTGATGAGCAATCAAAGTAATGATACCACAAT
CACTCAAAGGAGAGATACAATGAACGAACTTACCGAAGAGCAAAAACTTTTAATGGAAATGGTGCGCAATCTGGCGGTTA
GGGAAATTGCGCCGAGGGCCATAGAAATAGATGAGAATCATTCTTTTCCGGTGCATGCCCGGGACCTCTTCGCGGATCTG
GGGCTTCTGAGCCCGCTGGTGCCTGTCGAATACGGCGGAACAGGAATGGATATTACGACTTTTGCGATGGTCCTTGAGGA
AATCGGCAAGGTTTGCGCTTCCACCGCCCTGATGCTGCTCGCTCAGGCTGACGGCATGCTGTCCATCATCCTGGACGGCA
GCCCGGCCCTCAAGGAGAAGTATCTGCCCCGGTTTGGCGAAAAATCCACGCTGATGACCGCCTTTGCCGCCACAGAACCG
GGAGCCGGTTCGGATTTGCTGGCCATGAAAACCCGTGCAGTCAAGAAGGGCGACAAGTACGTGATCAACGGACAGAAATG
TTTTATCACCAATGGTTCTGTGGCTGACATCCTCACGGTGTGGGCTTATACGGATCCGTCAAAAGGCGCGAAAGGCATGA
GCACCTTTGTGGTGGAAAGAGGCACTCCCGGTTTGATTTACGGCCACAATGAAAAAAAGATGGGGATGCGTGGATGCCCC
AACTCCGAACTCTTCTTCGAGGACCTGGAAGTTCCTGCGGAAAACCTGGTCGGTGAAGAAGGCAAAGGATTCGCCTATCT
CATGGGTGCGCTTTCCATTAACCGTGTTTTCTGTGCATCCCAGGCTGTGGGCATTGCTCAGGGAGCTCTGGAAAGGGCCA
TGCAGCACACCCGCGAGCGTGAACAGTTCGGCAAGCCCATCGCCCATCTGACTCCGATCCAGTTCATGATCGCCGATATG
GCGACTGAAGTCGAAGCCGCGCGCCTCCTGGTCCGGAAGGCGACAACACTGCTCGATGCAAAAGACAAACGAGGACCACT
GATCGGTGGAATGGCCAAGACATTTGCCAGCGATACGGCGATGAAGGTGACGACCGACGCGGTTCAGGTTATGGGCGGGT
CGGGTTATATGCAGGAATACCAGGTGGAGCGAATGATGCGCGAGGCCAAGTTGACCCAGATTTACACGGGAACCAACCAG
ATCACCCGAATGGTCACCGGCCGCAGCCTGTTGTTTCCGTCGTAA

Upstream 100 bases:

>100_bases
AAAATCACCACCGATGCGATTCAGGTCTTTGGCGGATATGGCTACACGCATGATTATCCGGTGGAGCGCATGTTCCGGGA
TGCGAAACTGACCCAGATCT

Downstream 100 bases:

>100_bases
CTGAAGTCAATGTCAATGATTCAAGTAAACAGGACCTGCCGGTAACGGCAGGTCTGGATTTACCGCATCGGCCCCGCGCA
AGTCAGGGCAATCGGTTCCG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKGPIKFNALSLQGRSVMSNQSNDTTITQRRDTMNELTEEQKLLMEMVRNLAVREIAPRAIEIDENHSFPVHARDLFADL
GLLSPLVPVEYGGTGMDITTFAMVLEEIGKVCASTALMLLAQADGMLSIILDGSPALKEKYLPRFGEKSTLMTAFAATEP
GAGSDLLAMKTRAVKKGDKYVINGQKCFITNGSVADILTVWAYTDPSKGAKGMSTFVVERGTPGLIYGHNEKKMGMRGCP
NSELFFEDLEVPAENLVGEEGKGFAYLMGALSINRVFCASQAVGIAQGALERAMQHTREREQFGKPIAHLTPIQFMIADM
ATEVEAARLLVRKATTLLDAKDKRGPLIGGMAKTFASDTAMKVTTDAVQVMGGSGYMQEYQVERMMREAKLTQIYTGTNQ
ITRMVTGRSLLFPS

Sequences:

>Translated_414_residues
MKGPIKFNALSLQGRSVMSNQSNDTTITQRRDTMNELTEEQKLLMEMVRNLAVREIAPRAIEIDENHSFPVHARDLFADL
GLLSPLVPVEYGGTGMDITTFAMVLEEIGKVCASTALMLLAQADGMLSIILDGSPALKEKYLPRFGEKSTLMTAFAATEP
GAGSDLLAMKTRAVKKGDKYVINGQKCFITNGSVADILTVWAYTDPSKGAKGMSTFVVERGTPGLIYGHNEKKMGMRGCP
NSELFFEDLEVPAENLVGEEGKGFAYLMGALSINRVFCASQAVGIAQGALERAMQHTREREQFGKPIAHLTPIQFMIADM
ATEVEAARLLVRKATTLLDAKDKRGPLIGGMAKTFASDTAMKVTTDAVQVMGGSGYMQEYQVERMMREAKLTQIYTGTNQ
ITRMVTGRSLLFPS
>Mature_414_residues
MKGPIKFNALSLQGRSVMSNQSNDTTITQRRDTMNELTEEQKLLMEMVRNLAVREIAPRAIEIDENHSFPVHARDLFADL
GLLSPLVPVEYGGTGMDITTFAMVLEEIGKVCASTALMLLAQADGMLSIILDGSPALKEKYLPRFGEKSTLMTAFAATEP
GAGSDLLAMKTRAVKKGDKYVINGQKCFITNGSVADILTVWAYTDPSKGAKGMSTFVVERGTPGLIYGHNEKKMGMRGCP
NSELFFEDLEVPAENLVGEEGKGFAYLMGALSINRVFCASQAVGIAQGALERAMQHTREREQFGKPIAHLTPIQFMIADM
ATEVEAARLLVRKATTLLDAKDKRGPLIGGMAKTFASDTAMKVTTDAVQVMGGSGYMQEYQVERMMREAKLTQIYTGTNQ
ITRMVTGRSLLFPS

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=40.4255319148936, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=40.4255319148936, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI4557233, Length=381, Percent_Identity=40.6824146981627, Blast_Score=271, Evalue=9e-73,
Organism=Homo sapiens, GI226958412, Length=392, Percent_Identity=35.7142857142857, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI7656849, Length=393, Percent_Identity=34.8600508905852, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI4501859, Length=371, Percent_Identity=37.1967654986523, Blast_Score=241, Evalue=8e-64,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=36.3372093023256, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=33.7730870712401, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI76496475, Length=334, Percent_Identity=37.125748502994, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI4557235, Length=334, Percent_Identity=37.125748502994, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI21361497, Length=381, Percent_Identity=32.8083989501312, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=28.2321899736148, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7669494, Length=353, Percent_Identity=28.6118980169972, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI48976061, Length=347, Percent_Identity=27.3775216138329, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI211971008, Length=347, Percent_Identity=27.3775216138329, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI38505218, Length=338, Percent_Identity=26.9230769230769, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=32.8912466843501, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=28.2321899736148, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87082384, Length=283, Percent_Identity=27.5618374558304, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=397, Percent_Identity=36.7758186397985, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17534899, Length=386, Percent_Identity=36.7875647668394, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=37.9947229551451, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17538396, Length=416, Percent_Identity=34.8557692307692, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=34.6774193548387, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=33.4231805929919, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=33.6927223719677, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI71985184, Length=380, Percent_Identity=35.2631578947368, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=40, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI71985192, Length=315, Percent_Identity=35.2380952380952, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=33.4558823529412, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17551932, Length=358, Percent_Identity=31.0055865921788, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17505929, Length=351, Percent_Identity=31.0541310541311, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=220, Percent_Identity=36.8181818181818, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=27.3684210526316, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17531909, Length=235, Percent_Identity=31.063829787234, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17562446, Length=303, Percent_Identity=28.0528052805281, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=265, Percent_Identity=27.5471698113208, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=265, Percent_Identity=27.5471698113208, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531913, Length=170, Percent_Identity=28.2352941176471, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=41.3793103448276, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI21356377, Length=384, Percent_Identity=38.5416666666667, Blast_Score=261, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24666513, Length=369, Percent_Identity=36.0433604336043, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI21355753, Length=387, Percent_Identity=36.6925064599483, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=35.5437665782493, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI281363737, Length=341, Percent_Identity=35.4838709677419, Blast_Score=208, Evalue=7e-54,
Organism=Drosophila melanogaster, GI19920834, Length=388, Percent_Identity=28.0927835051546, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 45179; Mature: 45179

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGPIKFNALSLQGRSVMSNQSNDTTITQRRDTMNELTEEQKLLMEMVRNLAVREIAPRA
CCCCEEEEEEEECCCHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IEIDENHSFPVHARDLFADLGLLSPLVPVEYGGTGMDITTFAMVLEEIGKVCASTALMLL
EEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQADGMLSIILDGSPALKEKYLPRFGEKSTLMTAFAATEPGAGSDLLAMKTRAVKKGDKY
HHCCCEEEEEECCCHHHHHHHCCCCCCCHHHEEEEECCCCCCCCCHHHHHHHHHHCCCEE
VINGQKCFITNGSVADILTVWAYTDPSKGAKGMSTFVVERGTPGLIYGHNEKKMGMRGCP
EECCCEEEEECCCHHHHEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCC
NSELFFEDLEVPAENLVGEEGKGFAYLMGALSINRVFCASQAVGIAQGALERAMQHTRER
CCCEEHHHHCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFGKPIAHLTPIQFMIADMATEVEAARLLVRKATTLLDAKDKRGPLIGGMAKTFASDTA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCC
MKVTTDAVQVMGGSGYMQEYQVERMMREAKLTQIYTGTNQITRMVTGRSLLFPS
EEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKGPIKFNALSLQGRSVMSNQSNDTTITQRRDTMNELTEEQKLLMEMVRNLAVREIAPRA
CCCCEEEEEEEECCCHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IEIDENHSFPVHARDLFADLGLLSPLVPVEYGGTGMDITTFAMVLEEIGKVCASTALMLL
EEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQADGMLSIILDGSPALKEKYLPRFGEKSTLMTAFAATEPGAGSDLLAMKTRAVKKGDKY
HHCCCEEEEEECCCHHHHHHHCCCCCCCHHHEEEEECCCCCCCCCHHHHHHHHHHCCCEE
VINGQKCFITNGSVADILTVWAYTDPSKGAKGMSTFVVERGTPGLIYGHNEKKMGMRGCP
EECCCEEEEECCCHHHHEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCC
NSELFFEDLEVPAENLVGEEGKGFAYLMGALSINRVFCASQAVGIAQGALERAMQHTRER
CCCEEHHHHCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFGKPIAHLTPIQFMIADMATEVEAARLLVRKATTLLDAKDKRGPLIGGMAKTFASDTA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCC
MKVTTDAVQVMGGSGYMQEYQVERMMREAKLTQIYTGTNQITRMVTGRSLLFPS
EEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]