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The map label for this gene is bcd [H]

Identifier: 85375814

GI number: 85375814

Start: 3011418

End: 3012629

Strand: Reverse

Name: bcd [H]

Synonym: ELI_14935

Alternate gene names: 85375814

Gene position: 3012629-3011418 (Counterclockwise)

Preceding gene: 85375815

Following gene: 85375813

Centisome position: 98.7

GC content: 62.87

Gene sequence:

>1212_bases
ATGGCCACACAAATTGAGCCCGCAACCCAGACCGACGAAAACGCCTTCCGCGCGGAAGTGCAGCAGTTTCTGGCGGACAA
TTTTCCCGCCGAACTCAAGGGCCAGTCCAACGCACTAGCCGGCGTGGACGGCCCCACCAACGAAACGCCGGCGCAGACCA
AGTGGCGCGAAGCCGTGGGCGCGCGCGGCTGGGGCACCCCCACCTGGCCGAAGGAATACGGCGGCGGCGGCCTCACCAAG
GCGCAGGCGAAGATCATCGACCAAGAATTCGCCAAGGCGGGTGCCTACAACCCGATCGGCGGCATGGGCGTCATGATGTT
CGGCCCGACGCTGCTCGAATACGGCAACGAGGCACAGAAGCAGGAGCATATTCCGCCGATCTGCCGCGGCGAAATCCGCT
GGTGCCAGGGCTATTCGGAACCCAATGCCGGCTCTGACCTCGCGAACCTCCAGACCTTTGCCGAGGACAAGGGGGACCAC
TACCTTGTCAACGGCCAGAAGACCTGGACCAGCGGCGGCCAATGGGCCGACAAGTGCTTTGCAATTGTACGAACCGACAA
GAGCGACAAGCACAAGGGCATCAGCTTCATGCTGATCGACATGGACACGCCCGGCGTCGAAGTCCGCCCGATCACCATGA
TCAGCGGGACCAGCCCGTTCTGCGAAACCTTTTTCACCGACGTGAAGGTCCCGAAGGAAAACCTCGTCGGCGAGGAAGGC
CAGGGCTGGACCATCGGCAAGCGCCTTCTGCAGCACGAGCGCACCAACATCTCGGGCGGCGGCAGCCTCGCCCGTCTCAT
GGGCCAGAGCCTTGGCGATATCGCCAAGAAGTACCAGCCGACGGGCGCCGACGGCGAACTCGCCGATGCGGTGCTGCGCG
ACAAGATCGCTGATTTCGAGATCCGCTGGAACAGCTTCCTGCTCACTGCGCGCCGCGCGATGGAGGAAAGCAAGGCAGCT
GGCGGCGTCTCCGAAATCAGCTCTGTGCTCAAGAAGCTCGGCACCAAGCTGAGCCAGGAACGCAGCGAATTGCTGATCGA
AATCCGCGGGTTGCAGGGCCTCGGCTGGGAAGGCGACAGCTTCACCGACAGCGAGCTGGAAGCCGTGCGCGGCTGGCTCT
TCGGCAAGGCCACGACGATCTACGGCGGCTCGACCGAAATCCAGAACAACATCATTTCCAAGCGTGTCCTTGGCATGCTG
GATCACCAGTAA

Upstream 100 bases:

>100_bases
TGGTTCTTCACCTACCCGAACAACAATACTGACGGAGGGATTTTCGTCCCCGTAGCCTACATTCTTATCTGTCTTTCCTC
GATTCTTTGAGAAAACGCCC

Downstream 100 bases:

>100_bases
GAGAGGGGAGCTCGAACAATGGCAGTTCTCAACGAAGAACAGGAAATGCTGCGCGACATGGCGCGCGACTGGGCCACCAA
CGAAAGCCCGGTGACCGAGT

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MATQIEPATQTDENAFRAEVQQFLADNFPAELKGQSNALAGVDGPTNETPAQTKWREAVGARGWGTPTWPKEYGGGGLTK
AQAKIIDQEFAKAGAYNPIGGMGVMMFGPTLLEYGNEAQKQEHIPPICRGEIRWCQGYSEPNAGSDLANLQTFAEDKGDH
YLVNGQKTWTSGGQWADKCFAIVRTDKSDKHKGISFMLIDMDTPGVEVRPITMISGTSPFCETFFTDVKVPKENLVGEEG
QGWTIGKRLLQHERTNISGGGSLARLMGQSLGDIAKKYQPTGADGELADAVLRDKIADFEIRWNSFLLTARRAMEESKAA
GGVSEISSVLKKLGTKLSQERSELLIEIRGLQGLGWEGDSFTDSELEAVRGWLFGKATTIYGGSTEIQNNIISKRVLGML
DHQ

Sequences:

>Translated_403_residues
MATQIEPATQTDENAFRAEVQQFLADNFPAELKGQSNALAGVDGPTNETPAQTKWREAVGARGWGTPTWPKEYGGGGLTK
AQAKIIDQEFAKAGAYNPIGGMGVMMFGPTLLEYGNEAQKQEHIPPICRGEIRWCQGYSEPNAGSDLANLQTFAEDKGDH
YLVNGQKTWTSGGQWADKCFAIVRTDKSDKHKGISFMLIDMDTPGVEVRPITMISGTSPFCETFFTDVKVPKENLVGEEG
QGWTIGKRLLQHERTNISGGGSLARLMGQSLGDIAKKYQPTGADGELADAVLRDKIADFEIRWNSFLLTARRAMEESKAA
GGVSEISSVLKKLGTKLSQERSELLIEIRGLQGLGWEGDSFTDSELEAVRGWLFGKATTIYGGSTEIQNNIISKRVLGML
DHQ
>Mature_402_residues
ATQIEPATQTDENAFRAEVQQFLADNFPAELKGQSNALAGVDGPTNETPAQTKWREAVGARGWGTPTWPKEYGGGGLTKA
QAKIIDQEFAKAGAYNPIGGMGVMMFGPTLLEYGNEAQKQEHIPPICRGEIRWCQGYSEPNAGSDLANLQTFAEDKGDHY
LVNGQKTWTSGGQWADKCFAIVRTDKSDKHKGISFMLIDMDTPGVEVRPITMISGTSPFCETFFTDVKVPKENLVGEEGQ
GWTIGKRLLQHERTNISGGGSLARLMGQSLGDIAKKYQPTGADGELADAVLRDKIADFEIRWNSFLLTARRAMEESKAAG
GVSEISSVLKKLGTKLSQERSELLIEIRGLQGLGWEGDSFTDSELEAVRGWLFGKATTIYGGSTEIQNNIISKRVLGMLD
HQ

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=346, Percent_Identity=29.4797687861272, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI226958414, Length=234, Percent_Identity=32.0512820512821, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI226958412, Length=220, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI7656849, Length=350, Percent_Identity=27.4285714285714, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4557231, Length=337, Percent_Identity=26.4094955489614, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI187960098, Length=337, Percent_Identity=26.4094955489614, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI4501859, Length=334, Percent_Identity=26.3473053892216, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI38505218, Length=232, Percent_Identity=31.0344827586207, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4557235, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI76496475, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI211971008, Length=145, Percent_Identity=33.7931034482759, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI48976061, Length=145, Percent_Identity=33.7931034482759, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI21361497, Length=262, Percent_Identity=27.4809160305344, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4501857, Length=313, Percent_Identity=23.3226837060703, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786223, Length=361, Percent_Identity=21.3296398891967, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=345, Percent_Identity=26.0869565217391, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=392, Percent_Identity=27.2959183673469, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=408, Percent_Identity=24.2647058823529, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=347, Percent_Identity=26.2247838616715, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=192, Percent_Identity=30.7291666666667, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=192, Percent_Identity=30.7291666666667, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=214, Percent_Identity=30.3738317757009, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=212, Percent_Identity=28.3018867924528, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=193, Percent_Identity=29.5336787564767, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=208, Percent_Identity=27.4038461538462, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=228, Percent_Identity=30.7017543859649, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=206, Percent_Identity=30.5825242718447, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=228, Percent_Identity=30.7017543859649, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=333, Percent_Identity=24.9249249249249, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=147, Percent_Identity=31.9727891156463, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356377, Length=352, Percent_Identity=31.5340909090909, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646207, Length=355, Percent_Identity=29.8591549295775, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355753, Length=313, Percent_Identity=29.3929712460064, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24666513, Length=194, Percent_Identity=28.8659793814433, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24660351, Length=297, Percent_Identity=27.6094276094276, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363737, Length=202, Percent_Identity=27.7227722772277, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920834, Length=364, Percent_Identity=23.9010989010989, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43944; Mature: 43813

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQIEPATQTDENAFRAEVQQFLADNFPAELKGQSNALAGVDGPTNETPAQTKWREAVG
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCEECCCCCCCCCCCHHHHHHHHC
ARGWGTPTWPKEYGGGGLTKAQAKIIDQEFAKAGAYNPIGGMGVMMFGPTLLEYGNEAQK
CCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHH
QEHIPPICRGEIRWCQGYSEPNAGSDLANLQTFAEDKGDHYLVNGQKTWTSGGQWADKCF
HHCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCEECCCCCHHHHHHE
AIVRTDKSDKHKGISFMLIDMDTPGVEVRPITMISGTSPFCETFFTDVKVPKENLVGEEG
EEEECCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHCCCCHHHCCCCCC
QGWTIGKRLLQHERTNISGGGSLARLMGQSLGDIAKKYQPTGADGELADAVLRDKIADFE
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEE
IRWNSFLLTARRAMEESKAAGGVSEISSVLKKLGTKLSQERSELLIEIRGLQGLGWEGDS
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
FTDSELEAVRGWLFGKATTIYGGSTEIQNNIISKRVLGMLDHQ
CCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATQIEPATQTDENAFRAEVQQFLADNFPAELKGQSNALAGVDGPTNETPAQTKWREAVG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCEECCCCCCCCCCCHHHHHHHHC
ARGWGTPTWPKEYGGGGLTKAQAKIIDQEFAKAGAYNPIGGMGVMMFGPTLLEYGNEAQK
CCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHH
QEHIPPICRGEIRWCQGYSEPNAGSDLANLQTFAEDKGDHYLVNGQKTWTSGGQWADKCF
HHCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCEECCCCCHHHHHHE
AIVRTDKSDKHKGISFMLIDMDTPGVEVRPITMISGTSPFCETFFTDVKVPKENLVGEEG
EEEECCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHCCCCHHHCCCCCC
QGWTIGKRLLQHERTNISGGGSLARLMGQSLGDIAKKYQPTGADGELADAVLRDKIADFE
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEE
IRWNSFLLTARRAMEESKAAGGVSEISSVLKKLGTKLSQERSELLIEIRGLQGLGWEGDS
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
FTDSELEAVRGWLFGKATTIYGGSTEIQNNIISKRVLGMLDHQ
CCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]